| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinogenesis | D063646 | 3 associated lipids |
| Tongue Neoplasms | D014062 | 15 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
Total
3
ursolic acid
Ursolic acid is a lipid of Prenol Lipids (PR) class. Ursolic acid is associated with abnormalities such as Aortic Valve Insufficiency, Marles Greenberg Persaud syndrome, Infection, Arthritis and Dermatitis. The involved functions are known as Transcription, Genetic, Metabolic Inhibition, Cell physiology, Cell Differentiation process and Apoptosis. Ursolic acid often locates in Blood, Bacterial Fimbria, soluble, Extracellular and Microglial. The associated genes with ursolic acid are STAT3 gene, Genes, Reporter, IMPACT gene, ITSN2 gene and casamino acids. The related lipids are lysophosphatidic acid, Lipopolysaccharides, Steroids, cholanic acid and 1-palmitoyl-2-oleoylphosphatidylethanolamine. The related experimental models are Mouse Model, Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of ursolic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with ursolic acid?
ursolic acid is suspected in Aortic Valve Insufficiency, Dermatitis, Muscular Atrophy, Bury, Marles Greenberg Persaud syndrome, Obesity and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with ursolic acid
PubChem Associated disorders and diseases
What pathways are associated with ursolic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with ursolic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with ursolic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with ursolic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with ursolic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with ursolic acid?
Mouse Model
Mouse Model are used in the study 'Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.' (Prasad S et al., 2012) and Mouse Model are used in the study 'A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.' (Wilkinson K et al., 2011).
Knock-out
Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Cancer Model
Cancer Model are used in the study 'Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.' (Cho J et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with ursolic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:15460442 | ||||
| Aggarwal BB et al. | From chemoprevention to chemotherapy: common targets and common goals. | 2004 | Expert Opin Investig Drugs | pmid:15461561 |
| Mallavadhani UV et al. | Antimicrobial activity of some pentacyclic triterpenes and their synthesized 3-O-lipophilic chains. | 2004 | Biol. Pharm. Bull. | pmid:15467198 |
| Saeidnia S et al. | Two new monoterpene glycosides and trypanocidal terpenoids from Dracocephalum kotschyi. | 2004 | Chem. Pharm. Bull. | pmid:15467247 |
| Tokar M and Klimek B | Isolation and identification of biologically active compounds from Forsythia viridissima flowers. | 2004 May-Jun | Acta Pol Pharm | pmid:15481244 |
| Neurath AR et al. | Punica granatum (Pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide. | 2004 | BMC Infect. Dis. | pmid:15485580 |
| Dorai T and Aggarwal BB | Role of chemopreventive agents in cancer therapy. | 2004 | Cancer Lett. | pmid:15488631 |
| Taketa AT et al. | Triterpenoids from Brazilian Ilex species and their in vitro antitrypanosomal activity. | 2004 | J. Nat. Prod. | pmid:15497942 |
| pmid:15499915 | ||||
| pmid:15519169 | ||||
| Harmand PO et al. | Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells. | 2005 | Int. J. Cancer | pmid:15523687 |
| Gao J et al. | Hepatoprotective activity of Terminalia catappa L. leaves and its two triterpenoids. | 2004 | J. Pharm. Pharmacol. | pmid:15525453 |
| Achiwa Y et al. | Ursolic acid induces Bax-dependent apoptosis through the caspase-3 pathway in endometrial cancer SNG-II cells. | 2005 | Oncol. Rep. | pmid:15583801 |
| Park JH et al. | Antiinflammatory activity of Synurus deltoides. | 2004 | Phytother Res | pmid:15597310 |
| León F et al. | Lanostanoid triterpenes from Laetiporus sulphureus and apoptosis induction on HL-60 human myeloid leukemia cells. | 2004 | J. Nat. Prod. | pmid:15620242 |
| pmid:15621609 | ||||
| pmid:15631502 | ||||
| Yoshida M et al. | Antiproliferative constituents from Umbelliferae plants VII. Active triterpenes and rosmarinic acid from Centella asiatica. | 2005 | Biol. Pharm. Bull. | pmid:15635187 |
| Urech K et al. | Apoptosis inducing activity of viscin, a lipophilic extract from Viscum album L. | 2005 | J. Pharm. Pharmacol. | pmid:15638998 |
| pmid:15640935 |