MeSH term | MeSH ID | Detail |
---|---|---|
Dermatitis, Contact | D003877 | 59 associated lipids |
Tongue Neoplasms | D014062 | 15 associated lipids |
Carcinogenesis | D063646 | 3 associated lipids |
Ursolic acid is a lipid of Prenol Lipids (PR) class. Ursolic acid is associated with abnormalities such as Aortic Valve Insufficiency, Marles Greenberg Persaud syndrome, Infection, Arthritis and Dermatitis. The involved functions are known as Transcription, Genetic, Metabolic Inhibition, Cell physiology, Cell Differentiation process and Apoptosis. Ursolic acid often locates in Blood, Bacterial Fimbria, soluble, Extracellular and Microglial. The associated genes with ursolic acid are STAT3 gene, Genes, Reporter, IMPACT gene, ITSN2 gene and casamino acids. The related lipids are lysophosphatidic acid, Lipopolysaccharides, Steroids, cholanic acid and 1-palmitoyl-2-oleoylphosphatidylethanolamine. The related experimental models are Mouse Model, Knock-out and Cancer Model.
To understand associated biological information of ursolic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
ursolic acid is suspected in Aortic Valve Insufficiency, Dermatitis, Muscular Atrophy, Bury, Marles Greenberg Persaud syndrome, Obesity and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with ursolic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Dermatitis, Contact | D003877 | 59 associated lipids |
Tongue Neoplasms | D014062 | 15 associated lipids |
Carcinogenesis | D063646 | 3 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.' (Prasad S et al., 2012) and Mouse Model are used in the study 'A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.' (Wilkinson K et al., 2011).
Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Cancer Model are used in the study 'Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.' (Cho J et al., 2015).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ma XH et al. | [Studies on the preventive and therapeutic effects of ursolic acid (UA) on acute hepatic injury in rats]. | 1986 | Yao Xue Xue Bao | pmid:3776541 |
Meng YQ et al. | [Synthesis and anti-tumor activity of ursolic acid derivatives]. | 2011 | Yao Xue Xue Bao | pmid:21800543 |
Ahumada C et al. | Influence of the parasite Viscum cruciatum Sieber on the chemical constituents of Crataegus monogyna Jacq. | 2001 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:11837662 |
Jedinák A et al. | Antiprotease and antimetastatic activity of ursolic acid isolated from Salvia officinalis. | 2006 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:17294686 |
Li D et al. | [Effects of ursolic acid on c-Cbl-associated protein expression in 3T3-L1 adipocytes with insulin resistance]. | 2012 | Zhong Xi Yi Jie He Xue Bao | pmid:22883405 |
Wang L et al. | [Effects of ursolic acid in ameliorating insulin resistance in liver of KKAy mice via peroxisome proliferator-activated receptors α and γ]. | 2012 | Zhong Xi Yi Jie He Xue Bao | pmid:22805086 |
Zhang HP and Tao L | [Studies on the chemical constituents of Buddleja albiflora (II)]. | 2010 | Zhong Yao Cai | pmid:21049618 |
Yu XH et al. | [Study on ursolic acid extraction rate by ultramicro smashing and conventional smashing from leaves of Paulownia fortunei]. | 2008 | Zhong Yao Cai | pmid:19230417 |
Duan WD et al. | [Chemical constituents from the flower of Paulownia fortunei( seem. ) Hemsl]. | 2007 | Zhong Yao Cai | pmid:17571764 |
Yuan G and Yi Y | [Studies on chemical constituents of the roots of Salacia hainanensis]. | 2005 | Zhong Yao Cai | pmid:15934239 |