ursolic acid

Ursolic acid is a lipid of Prenol Lipids (PR) class. Ursolic acid is associated with abnormalities such as Aortic Valve Insufficiency, Marles Greenberg Persaud syndrome, Infection, Arthritis and Dermatitis. The involved functions are known as Transcription, Genetic, Metabolic Inhibition, Cell physiology, Cell Differentiation process and Apoptosis. Ursolic acid often locates in Blood, Bacterial Fimbria, soluble, Extracellular and Microglial. The associated genes with ursolic acid are STAT3 gene, Genes, Reporter, IMPACT gene, ITSN2 gene and casamino acids. The related lipids are lysophosphatidic acid, Lipopolysaccharides, Steroids, cholanic acid and 1-palmitoyl-2-oleoylphosphatidylethanolamine. The related experimental models are Mouse Model, Knock-out and Cancer Model.

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Introduction

To understand associated biological information of ursolic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ursolic acid?

ursolic acid is suspected in Aortic Valve Insufficiency, Dermatitis, Muscular Atrophy, Bury, Marles Greenberg Persaud syndrome, Obesity and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ursolic acid

MeSH term MeSH ID Detail
Dermatitis, Contact D003877 59 associated lipids
Tongue Neoplasms D014062 15 associated lipids
Carcinogenesis D063646 3 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with ursolic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ursolic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ursolic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ursolic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ursolic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ursolic acid?

Mouse Model

Mouse Model are used in the study 'Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.' (Prasad S et al., 2012) and Mouse Model are used in the study 'A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.' (Wilkinson K et al., 2011).

Knock-out

Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Cancer Model

Cancer Model are used in the study 'Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.' (Cho J et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ursolic acid

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Authors Title Published Journal PubMed Link
Guo Y et al. [Quantitative determination of ursolic acid in folium Ilicis cornutae (gouguye) gathered in different and periods]. 1995 Zhongguo Zhong Yao Za Zhi pmid:8679072
Wen D et al. [Studies on chemical constituents of Ilex Merr]. 1999 Zhongguo Zhong Yao Za Zhi pmid:12205946
Liu CH and Liu Y [Determination of ursolic acid in herba of Verbena officinalis by HPLC]. 2002 Zhongguo Zhong Yao Za Zhi pmid:12776531
Tu P et al. [Fat soluble constituents of the leaves of Vaccinium bracteatum Thunb]. 1997 Zhongguo Zhong Yao Za Zhi pmid:11038902
Yao Z et al. [Triterpenoids from leaves of Ilex cornuta]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19639785
Li YL et al. [Studies on chemical constituents from Serissa serissoides]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17583202
Sun M et al. [Experimental study on treating hyperlipidemic fatty liver with Taizhi'an capsule]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17583205
Zhang GP et al. [Effect of ursolic acid on caspase-3 and PARP expression of human MCF-7 cells]. 2006 Zhongguo Zhong Yao Za Zhi pmid:16570804
Song LL et al. [Determination of ursolic acid of Liuwei Dihuangwan simulation samples by NIR]. 2006 Zhongguo Zhong Yao Za Zhi pmid:17165581
Xue YM et al. [Determination of ursolic acid of Sambucus adnata]. 2013 Zhongguo Zhong Yao Za Zhi pmid:24010309