MeSH term | MeSH ID | Detail |
---|---|---|
Dermatitis, Contact | D003877 | 59 associated lipids |
Tongue Neoplasms | D014062 | 15 associated lipids |
Carcinogenesis | D063646 | 3 associated lipids |
Ursolic acid is a lipid of Prenol Lipids (PR) class. Ursolic acid is associated with abnormalities such as Aortic Valve Insufficiency, Marles Greenberg Persaud syndrome, Infection, Arthritis and Dermatitis. The involved functions are known as Transcription, Genetic, Metabolic Inhibition, Cell physiology, Cell Differentiation process and Apoptosis. Ursolic acid often locates in Blood, Bacterial Fimbria, soluble, Extracellular and Microglial. The associated genes with ursolic acid are STAT3 gene, Genes, Reporter, IMPACT gene, ITSN2 gene and casamino acids. The related lipids are lysophosphatidic acid, Lipopolysaccharides, Steroids, cholanic acid and 1-palmitoyl-2-oleoylphosphatidylethanolamine. The related experimental models are Mouse Model, Knock-out and Cancer Model.
To understand associated biological information of ursolic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
ursolic acid is suspected in Aortic Valve Insufficiency, Dermatitis, Muscular Atrophy, Bury, Marles Greenberg Persaud syndrome, Obesity and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with ursolic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Dermatitis, Contact | D003877 | 59 associated lipids |
Tongue Neoplasms | D014062 | 15 associated lipids |
Carcinogenesis | D063646 | 3 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.' (Prasad S et al., 2012) and Mouse Model are used in the study 'A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.' (Wilkinson K et al., 2011).
Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Cancer Model are used in the study 'Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.' (Cho J et al., 2015).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Tan J et al. | [Ursolic acid induces apoptosis in colon cancer HT-29 cells]. | 2006 | Zhonghua Zhong Liu Za Zhi | pmid:16750011 |
Wang Q et al. | Extract and identify ingredient from Ligustrum Lucidum Ait and study its effect to periodontal pathogen. | 2002 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:12425858 |
Shen YM et al. | [Effect of ursolic acid on proliferation and apoptosis of hepatic stellate cells in vitro]. | 2008 | Zhonghua Gan Zang Bing Za Zhi | pmid:18423155 |
Wang MY et al. | [Studies on the chemical constituents from stem of Chirita longgangensis var. Hongyao]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:16706021 |
Guo Y et al. | [Quantitative determination of ursolic acid in folium Ilicis cornutae (gouguye) gathered in different and periods]. | 1995 | Zhongguo Zhong Yao Za Zhi | pmid:8679072 |
Yao Z et al. | [Triterpenoids from leaves of Ilex cornuta]. | 2009 | Zhongguo Zhong Yao Za Zhi | pmid:19639785 |
Liu CH and Liu Y | [Determination of ursolic acid in herba of Verbena officinalis by HPLC]. | 2002 | Zhongguo Zhong Yao Za Zhi | pmid:12776531 |
Chen Y et al. | [Preparation and transdermal diffusion of ursolic acid ethosomes]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:21809568 |
Wen ZM and Xu LX | [Isolation and elucidation of chemical constituents of Shandanshaoyao Decoction(I)]. | 2001 | Zhongguo Zhong Yao Za Zhi | pmid:12528509 |
Yan H et al. | [Optimization of biotransformation of ursolic acid by alternaria longipes]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23189734 |