| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
Total
1
Lycopene
Lycopene is a lipid of Prenol Lipids (PR) class. Lycopene is associated with abnormalities such as Consumption-archaic term for TB, Chronic disease, Dehydration, furuncle and Cardiovascular Diseases. The involved functions are known as Cell Differentiation process, Signal Transduction, Biochemical Pathway, Mutation and IGF-1 Signaling Pathway. Lycopene often locates in Body tissue, Hepatic, Blood, Adipose tissue and Structure of parenchyma of lung. The associated genes with Lycopene are EPB41L2 gene, VEGFB gene, P4HTM gene, FATE1 gene and SLC33A1 gene. The related lipids are Micelles, Liposomes, Total cholesterol, Steroids and apo-10'-lycopenoic acid. The related experimental models are Mouse Model, Knock-out, Cancer Model, Transgenic Model and Xenograft Model.
Cross Reference
Introduction
To understand associated biological information of Lycopene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lycopene?
Lycopene is suspected in Chronic disease, Cardiovascular Diseases, Atherosclerosis, Congenital contractural arachnodactyly, Myocardial Infarction, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lycopene
PubChem Associated disorders and diseases
What pathways are associated with Lycopene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lycopene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Lycopene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Lycopene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Lycopene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Lycopene?
Cancer Model
Cancer Model are used in the study 'Lack of chemopreventive effects of lycopene and curcumin on experimental rat prostate carcinogenesis.' (Imaida K et al., 2001), Cancer Model are used in the study 'Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention.' (Chen L et al., 2001), Cancer Model are used in the study 'Re: Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets.' (Limpens J et al., 2004), Cancer Model are used in the study 'Lycopene inhibits IGF-I signal transduction and growth in normal prostate epithelial cells by decreasing DHT-modulated IGF-I production in co-cultured reactive stromal cells.' (Liu X et al., 2008) and Cancer Model are used in the study 'Can smoke-exposed ferrets be utilized to unravel the mechanisms of action of lycopene?' (Wang XD, 2005).
Knock-out
Knock-out are used in the study 'Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice.' (Ip BC et al., 2014), Knock-out are used in the study 'In silico identification of gene amplification targets for improvement of lycopene production.' (Choi HS et al., 2010) and Knock-out are used in the study 'Dietary tomato powder inhibits alcohol-induced hepatic injury by suppressing cytochrome p450 2E1 induction in rodent models.' (Stice CP et al., 2015).
Mouse Model
Mouse Model are used in the study 'Tomatoes, tomato-based products, lycopene, and cancer: review of the epidemiologic literature.' (Giovannucci E, 1999), Mouse Model are used in the study 'Prolonged tomato juice consumption has no effect on cell-mediated immunity of well-nourished elderly men and women.' (Watzl B et al., 2000) and Mouse Model are used in the study 'Executive summary report.' (Davis CD et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Lycopene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Weisburger JH et al. | Inhibition of PhIP mutagenicity by caffeine, lycopene, daidzein, and genistein. | 1998 | Mutat. Res. | pmid:9725998 |
| Lycopene. Another good reason to eat tomatoes. | 1998 | Mayo Clin Health Lett | pmid:9727334 | |
| Simon Giavarotti KA et al. | Liver microsomal parameters related to oxidative stress and antioxidant systems in hyperthyroid rats subjected to acute lindane treatment. | 1998 | Free Radic. Res. | pmid:9733020 |
| Brown Thomas J et al. | The stability of retinol, alpha-tocopherol, trans-lycopene, and trans-beta-carotene in liquid-frozen and lyophilized serum. | 1998 | Clin. Chim. Acta | pmid:9760021 |
| Collins AR et al. | Oxidative DNA damage measured in human lymphocytes: large differences between sexes and between countries, and correlations with heart disease mortality rates. | 1998 | FASEB J. | pmid:9761783 |
| Pastori M et al. | Lycopene in association with alpha-tocopherol inhibits at physiological concentrations proliferation of prostate carcinoma cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9784387 |
| Rao AV and Agarwal S | Bioavailability and in vivo antioxidant properties of lycopene from tomato products and their possible role in the prevention of cancer. | 1998 | Nutr Cancer | pmid:9795972 |
| Black HS | Radical interception by carotenoids and effects on UV carcinogenesis. | 1998 | Nutr Cancer | pmid:9795974 |
| Palan PR et al. | Plasma levels of beta-carotene, lycopene, canthaxanthin, retinol, and alpha- and tau-tocopherol in cervical intraepithelial neoplasia and cancer. | 1996 | Clin. Cancer Res. | pmid:9816105 |
| Glise D et al. | Comparative distribution of beta-carotene and lycopene after intraperitoneal administration in mice. | 1998 Sep-Oct | In Vivo | pmid:9827350 |
| Agarwal S and Rao AV | Tomato lycopene and low density lipoprotein oxidation: a human dietary intervention study. | 1998 | Lipids | pmid:9832077 |
| Franko M et al. | Determination of trans-beta-carotene and other carotenoids in blood plasma using high-performance liquid chromatography and thermal lens detection. | 1998 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9832359 |
| Tatsuzawa H et al. | Inactivation of bacterial respiratory chain enzymes by singlet oxygen. | 1998 | FEBS Lett. | pmid:9845348 |
| Paetau I et al. | Chronic ingestion of lycopene-rich tomato juice or lycopene supplements significantly increases plasma concentrations of lycopene and related tomato carotenoids in humans. | 1998 | Am. J. Clin. Nutr. | pmid:9846845 |
| Narisawa T et al. | Prevention of N-methylnitrosourea-induced colon carcinogenesis in F344 rats by lycopene and tomato juice rich in lycopene. | 1998 | Jpn. J. Cancer Res. | pmid:9849577 |
| Faulks RM et al. | Changes in plasma carotenoid and vitamin E profile during supplementation with oil palm fruit carotenoids. | 1998 | J. Lab. Clin. Med. | pmid:9851741 |
| Hsueh YM et al. | Low serum carotene level and increased risk of ischemic heart disease related to long-term arsenic exposure. | 1998 | Atherosclerosis | pmid:9862173 |
| Bartley GE et al. | Two Arabidopsis thaliana carotene desaturases, phytoene desaturase and zeta-carotene desaturase, expressed in Escherichia coli, catalyze a poly-cis pathway to yield pro-lycopene. | 1999 | Eur. J. Biochem. | pmid:9914519 |
| Aebischer CP et al. | Simultaneous determination of retinol, tocopherols, carotene, lycopene, and xanthophylls in plasma by means of reversed-phase high-performance liquid chromatography. | 1999 | Meth. Enzymol. | pmid:9916214 |
| Ford ES et al. | Diabetes mellitus and serum carotenoids: findings from the Third National Health and Nutrition Examination Survey. | 1999 | Am. J. Epidemiol. | pmid:9921962 |
| Granado F et al. | Lutein ester in serum after lutein supplementation in human subjects. | 1998 | Br. J. Nutr. | pmid:9924266 |
| Porrini M et al. | Absorption of lycopene from single or daily portions of raw and processed tomato. | 1998 | Br. J. Nutr. | pmid:9924277 |
| Hayes RB et al. | Dietary factors and risks for prostate cancer among blacks and whites in the United States. | 1999 | Cancer Epidemiol. Biomarkers Prev. | pmid:9950236 |
| Herschberg PI | Prostate cancer screening. | 1999 | Cleve Clin J Med | pmid:9988958 |
| Lyle BJ et al. | Serum carotenoids and tocopherols and incidence of age-related nuclear cataract. | 1999 | Am. J. Clin. Nutr. | pmid:9989692 |