Zeaxanthin

Zeaxanthin is a lipid of Prenol Lipids (PR) class. Zeaxanthin is associated with abnormalities such as Disintegration (morphologic abnormality), Alkalemia, Age related macular degeneration, Visual impairment and Consumption-archaic term for TB. The involved functions are known as Signal, Regulation, Energy Transfer, Process and Pigment. Zeaxanthin often locates in Chloroplast thylakoids, reaction center, Tissue membrane, PSII associated light-harvesting complex II and Thylakoid Membrane. The associated genes with Zeaxanthin are PRB2 gene, Structural gene, Polypeptides, Genes, Bacterial and Genes, rRNA. The related lipids are Membrane Lipids, Micelles, Fatty Acids, Lipid Peroxides and monogalactosyldiacylglycerol. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Zeaxanthin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Zeaxanthin?

Zeaxanthin is suspected in Dermatitis, Phototoxic, Age related macular degeneration, Cataract, Disintegration, Reflex Epilepsy, Photosensitive, Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Zeaxanthin

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Zeaxanthin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Zeaxanthin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Zeaxanthin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Zeaxanthin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Zeaxanthin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Zeaxanthin?

Knock-out

Knock-out are used in the study 'Zeaxanthin binds to light-harvesting complex stress-related protein to enhance nonphotochemical quenching in Physcomitrella patens.' (Pinnola A et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Zeaxanthin

Download all related citations
Per page 10 20 50 100 | Total 1142
Authors Title Published Journal PubMed Link
Frankenfeld CL et al. Fruit and vegetable intakes in relation to plasma nutrient concentrations in women in Shanghai, China. 2012 Public Health Nutr pmid:21729475
Talegawkar SA et al. Carotenoid intakes, assessed by food-frequency questionnaires (FFQs), are associated with serum carotenoid concentrations in the Jackson Heart Study: validation of the Jackson Heart Study Delta NIRI Adult FFQs. 2008 Public Health Nutr pmid:18053294
Sousa-Martins D et al. Use of lutein and zeaxanthin alone or combined with Brilliant Blue to identify intraocular structures intraoperatively. 2012 Retina (Philadelphia, Pa.) pmid:22450514
You QS et al. REPRODUCIBILITY OF MACULAR PIGMENT OPTICAL DENSITY MEASUREMENT BY TWO-WAVELENGTH AUTOFLUORESCENCE IN A CLINICAL SETTING. 2016 Retina (Philadelphia, Pa.) pmid:26655614
Zeimer MB et al. Macular telangiectasia: patterns of distribution of macular pigment and response to supplementation. 2010 Retina (Philadelphia, Pa.) pmid:20671587
Helb HM et al. Abnormal macular pigment distribution in type 2 idiopathic macular telangiectasia. 2008 Retina (Philadelphia, Pa.) pmid:18536596
Lai Y et al. Functional and morphologic benefits in early detection of neovascular age-related macular degeneration using the preferential hyperacuity perimeter. 2011 Retina (Philadelphia, Pa.) pmid:21610564
Rosales-Loaiza N et al. [Growth and metabolite production of the marine cyanobacterium Synechococcus sp. (Chroococcales) in function to irradiance]. 2008 Rev. Biol. Trop. pmid:19256416
Hamułka J and Nogal D [The assessment and characteristic of dietary supplements with lutein and zeaxanthin on the Polish pharmaceutical market]. 2008 Rocz Panstw Zakl Hig pmid:18666622
Xu P et al. Molecular insights into Zeaxanthin-dependent quenching in higher plants. 2015 Sci Rep pmid:26323786
Faivre B et al. Immune activation rapidly mirrored in a secondary sexual trait. 2003 Science pmid:12677062
Holt NE et al. Carotenoid cation formation and the regulation of photosynthetic light harvesting. 2005 Science pmid:15662017
Ahn TK et al. Architecture of a charge-transfer state regulating light harvesting in a plant antenna protein. 2008 Science pmid:18467588
Olson JH et al. Nutritional supplementation and age-related macular degeneration. 2011 Semin Ophthalmol pmid:21609225
Astner S et al. Dietary lutein/zeaxanthin partially reduces photoaging and photocarcinogenesis in chronically UVB-irradiated Skh-1 hairless mice. 2007 Skin Pharmacol Physiol pmid:17717424
Palombo P et al. Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study. 2007 Skin Pharmacol Physiol pmid:17446716
Imagama S et al. The effect of β-carotene on lumbar osteophyte formation. 2011 Spine pmid:21673632
Ahmed SS et al. The macular xanthophylls. 2005 Mar-Apr Surv Ophthalmol pmid:15749308
Loane E et al. Transport and retinal capture of lutein and zeaxanthin with reference to age-related macular degeneration. 2008 Jan-Feb Surv Ophthalmol pmid:18191658
Asker D et al. Mesoflavibacter zeaxanthinifaciens gen. nov., sp. nov., a novel zeaxanthin-producing marine bacterium of the family Flavobacteriaceae. 2007 Syst. Appl. Microbiol. pmid:17276025
Zhang W and Dubcovsky J Association between allelic variation at the Phytoene synthase 1 gene and yellow pigment content in the wheat grain. 2008 Theor. Appl. Genet. pmid:18193186
Yu B et al. Enhancing the carotenoid content of Brassica napus seeds by downregulating lycopene epsilon cyclase. 2008 Transgenic Res. pmid:17851775
Shvaleva AL et al. Metabolic responses to water deficit in two Eucalyptus globulus clones with contrasting drought sensitivity. 2006 Tree Physiol. pmid:16356921
Franco AC et al. Photoinhibition, carotenoid composition and the co-regulation of photochemical and non-photochemical quenching in neotropical savanna trees. 2007 Tree Physiol. pmid:17267362
Robert B et al. Insights into the molecular dynamics of plant light-harvesting proteins in vivo. 2004 Trends Plant Sci. pmid:15358269
Farré G et al. Nutritious crops producing multiple carotenoids--a metabolic balancing act. 2011 Trends Plant Sci. pmid:21900035
Rohrmann S et al. Association between serum concentrations of micronutrients and lower urinary tract symptoms in older men in the Third National Health and Nutrition Examination Survey. 2004 Urology pmid:15351580
Bone RA et al. Preliminary identification of the human macular pigment. 1985 Vision Res. pmid:3832576
Bone RA et al. Optical density spectra of the macular pigment in vivo and in vitro. 1992 Vision Res. pmid:1502795
Hammond BR et al. Sex differences in macular pigment optical density: relation to plasma carotenoid concentrations and dietary patterns. 1996 Vision Res. pmid:8759440
Bernstein PS et al. The value of measurement of macular carotenoid pigment optical densities and distributions in age-related macular degeneration and other retinal disorders. 2010 Vision Res. pmid:19854211
Giovannucci DR and Stephenson RS Identification and distribution of dietary precursors of the Drosophila visual pigment chromophore: analysis of carotenoids in wild type and ninaD mutants by HPLC. 1999 Vision Res. pmid:10326132
Neelam K et al. Macular pigment and ocular biometry. 2006 Vision Res. pmid:16472837
Wenzel AJ et al. Macular pigment optical density and photophobia light threshold. 2006 Vision Res. pmid:17087988
Nolan JM et al. The impact of macular pigment augmentation on visual performance in normal subjects: COMPASS. 2011 Vision Res. pmid:21237188
Mózsik G et al. Involvement of serum retinoids and Leiden mutation in patients with esophageal, gastric, liver, pancreatic, and colorectal cancers in Hungary. 2005 World J. Gastroenterol. pmid:16437692
Jørgensen K and Skibsted LH Carotenoid scavenging of radicals. Effect of carotenoid structure and oxygen partial pressure on antioxidative activity. 1993 Z Lebensm Unters Forsch pmid:8511974
Lehmann-Kirk U et al. Inhibition of photosynthetic electron transport in tobacco chloroplasts and thylakoids of the blue green alga Oscillatoria chalybea by an antiserum to synthetic zeaxanthin. 1979 Z. Naturforsch., C, Biosci. pmid:44593
Breithaupt DE Enzymatic hydrolysis of carotenoid fatty acid esters of red pepper (Capsicum annuum L.) by a lipase from Candida rugosa. 2000 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:11204204
Wang ZX et al. [Comparison of lutein, zeaxanthin and β-carotene level in raw and cooked foods consumed in Beijing]. 2011 Zhonghua Yu Fang Yi Xue Za Zhi pmid:21418822
Koutsos EA et al. Absorption and ocular deposition of dietary lutein in marine mammals. 2013 May-Jun Zoo Biol. pmid:22753123
Smith CL et al. Naturally high plasma glucose levels in mourning doves (Zenaida macroura) do not lead to high levels of reactive oxygen species in the vasculature. 2011 Zoology (Jena) pmid:21600747