Zeaxanthin

Zeaxanthin is a lipid of Prenol Lipids (PR) class. Zeaxanthin is associated with abnormalities such as Disintegration (morphologic abnormality), Alkalemia, Age related macular degeneration, Visual impairment and Consumption-archaic term for TB. The involved functions are known as Signal, Regulation, Energy Transfer, Process and Pigment. Zeaxanthin often locates in Chloroplast thylakoids, reaction center, Tissue membrane, PSII associated light-harvesting complex II and Thylakoid Membrane. The associated genes with Zeaxanthin are PRB2 gene, Structural gene, Polypeptides, Genes, Bacterial and Genes, rRNA. The related lipids are Membrane Lipids, Micelles, Fatty Acids, Lipid Peroxides and monogalactosyldiacylglycerol. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Zeaxanthin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Zeaxanthin?

Zeaxanthin is suspected in Dermatitis, Phototoxic, Age related macular degeneration, Cataract, Disintegration, Reflex Epilepsy, Photosensitive, Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Zeaxanthin

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Zeaxanthin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Zeaxanthin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Zeaxanthin?


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What lipids are associated with Zeaxanthin?

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What genes are associated with Zeaxanthin?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Zeaxanthin?

Knock-out

Knock-out are used in the study 'Zeaxanthin binds to light-harvesting complex stress-related protein to enhance nonphotochemical quenching in Physcomitrella patens.' (Pinnola A et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Zeaxanthin

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Authors Title Published Journal PubMed Link
Büch K et al. FAD is a further essential cofactor of the NAD(P)H and O2-dependent zeaxanthin-epoxidase. 1995 FEBS Lett. pmid:8521963
Brady WE et al. Human serum carotenoid concentrations are related to physiologic and lifestyle factors. 1996 J. Nutr. pmid:8558292
Marin E et al. Molecular identification of zeaxanthin epoxidase of Nicotiana plumbaginifolia, a gene involved in abscisic acid biosynthesis and corresponding to the ABA locus of Arabidopsis thaliana. 1996 EMBO J. pmid:8665840
Hammond BR et al. Iris color and macular pigment optical density. 1996 Exp. Eye Res. pmid:8690039
Hammond BR et al. Sex differences in macular pigment optical density: relation to plasma carotenoid concentrations and dietary patterns. 1996 Vision Res. pmid:8759440
Tardy F and Havaux M Photosynthesis, chlorophyll fluorescence, light-harvesting system and photoinhibition resistance of a zeaxanthin-accumulating mutant of Arabidopsis thaliana. 1996 J. Photochem. Photobiol. B, Biol. pmid:8765663
Seaton GG et al. Novel amplification of non-photochemical chlorophyll fluorescence quenching following viral infection in Chlorella. 1996 FEBS Lett. pmid:8766724
Woodall AA et al. Dietary supplementation with carotenoids: effects on alpha-tocopherol levels and susceptibility of tissues to oxidative stress. 1996 Br. J. Nutr. pmid:8813904
Enger SM et al. Dietary intake of specific carotenoids and vitamins A, C, and E, and prevalence of colorectal adenomas. 1996 Cancer Epidemiol. Biomarkers Prev. pmid:8833613
Jyonouchi H et al. Effects of various carotenoids on cloned, effector-stage T-helper cell activity. 1996 Nutr Cancer pmid:8910913
Gabrielska J and Gruszecki WI Zeaxanthin (dihydroxy-beta-carotene) but not beta-carotene rigidifies lipid membranes: a 1H-NMR study of carotenoid-egg phosphatidylcholine liposomes. 1996 Biochim. Biophys. Acta pmid:8972700
Young AJ and Frank HA Energy transfer reactions involving carotenoids: quenching of chlorophyll fluorescence. 1996 J. Photochem. Photobiol. B, Biol. pmid:8988608
Bernstein PS et al. Retinal tubulin binds macular carotenoids. 1997 Invest. Ophthalmol. Vis. Sci. pmid:9008641
Carpenter KL et al. The carotenoids beta-carotene, canthaxanthin and zeaxanthin inhibit macrophage-mediated LDL oxidation. 1997 FEBS Lett. pmid:9013900
Borel P et al. Carotenoids in biological emulsions: solubility, surface-to-core distribution, and release from lipid droplets. 1996 J. Lipid Res. pmid:9026524
Pasamontes L et al. Isolation and characterization of the carotenoid biosynthesis genes of Flavobacterium sp. strain R1534. 1997 Gene pmid:9034310
Snodderly DM et al. Dietary manipulation of plasma carotenoid concentrations of squirrel monkeys (Saimiri sciureus). 1997 J. Nutr. pmid:9040555
Crabtree DV and Adler AJ Is beta-carotene an antioxidant? 1997 Med. Hypotheses pmid:9076701
Bone RA et al. Distribution of lutein and zeaxanthin stereoisomers in the human retina. 1997 Exp. Eye Res. pmid:9176055
Olmedilla B et al. Reference values for retinol, tocopherol, and main carotenoids in serum of control and insulin-dependent diabetic Spanish subjects. 1997 Clin. Chem. pmid:9191562
De Stefani E et al. Dietary fiber and risk of breast cancer: a case-control study in Uruguay. 1997 Nutr Cancer pmid:9200145
Ruban AV et al. Carotenoid-dependent oligomerization of the major chlorophyll a/b light harvesting complex of photosystem II of plants. 1997 Biochemistry pmid:9201929
Koonsvitsky BP et al. Olestra affects serum concentrations of alpha-tocopherol and carotenoids but not vitamin D or vitamin K status in free-living subjects. 1997 J. Nutr. pmid:9237960
Hammond BR et al. Dietary modification of human macular pigment density. 1997 Invest. Ophthalmol. Vis. Sci. pmid:9286268
Khachik F et al. Identification of lutein and zeaxanthin oxidation products in human and monkey retinas. 1997 Invest. Ophthalmol. Vis. Sci. pmid:9286269
Hammond BR et al. Density of the human crystalline lens is related to the macular pigment carotenoids, lutein and zeaxanthin. 1997 Optom Vis Sci pmid:9293517
Ruther A et al. Production of zeaxanthin in Escherichia coli transformed with different carotenogenic plasmids. 1997 Appl. Microbiol. Biotechnol. pmid:9299773
Zang LY et al. Absorbance changes of carotenoids in different solvents. 1997 Free Radic. Biol. Med. pmid:9358253
Woodall AA et al. Carotenoids and protection of phospholipids in solution or in liposomes against oxidation by peroxyl radicals: relationship between carotenoid structure and protective ability. 1997 Biochim. Biophys. Acta pmid:9367186
Mortensen A et al. Comparative mechanisms and rates of free radical scavenging by carotenoid antioxidants. 1997 FEBS Lett. pmid:9414102
Grolier P et al. In vitro and in vivo inhibition of beta-carotene dioxygenase activity by canthaxanthin in rat intestine. 1997 Arch. Biochem. Biophys. pmid:9434733
Forman MR et al. Effect of menstrual cycle phase on the concentration of individual carotenoids in lipoproteins of premenopausal women: a controlled dietary study. 1998 Am. J. Clin. Nutr. pmid:9440379
Depka B et al. Beta-carotene to zeaxanthin conversion in the rapid turnover of the D1 protein of photosystem II. 1998 FEBS Lett. pmid:9539164
Niyogi KK et al. Arabidopsis mutants define a central role for the xanthophyll cycle in the regulation of photosynthetic energy conversion. 1998 Plant Cell pmid:9668132
Lichtenthaler HK The stress concept in plants: an introduction. 1998 Ann. N. Y. Acad. Sci. pmid:9668620
Scheidegger R et al. The reaction of peroxynitrite with zeaxanthin. 1998 Nitric Oxide pmid:9706738
Gilmore AM et al. Quantitative analysis of the effects of intrathylakoid pH and xanthophyll cycle pigments on chlorophyll a fluorescence lifetime distributions and intensity in thylakoids. 1998 Biochemistry pmid:9753445
Bernstein PS et al. Raman detection of macular carotenoid pigments in intact human retina. 1998 Invest. Ophthalmol. Vis. Sci. pmid:9761278
Park JS et al. Dietary lutein absorption from marigold extract is rapid in BALB/c mice. 1998 J. Nutr. pmid:9772152
Takatsuka N et al. Effects of passive smoking on serum levels of carotenoids and alpha-tocopherol. 1998 J Epidemiol pmid:9782670
Sommerburg O et al. Fruits and vegetables that are sources for lutein and zeaxanthin: the macular pigment in human eyes. 1998 Br J Ophthalmol pmid:9828775
Landrum JT et al. Analysis of zeaxanthin distribution within individual human retinas. 1999 Meth. Enzymol. pmid:9916219