Zeaxanthin

Zeaxanthin is a lipid of Prenol Lipids (PR) class. Zeaxanthin is associated with abnormalities such as Disintegration (morphologic abnormality), Alkalemia, Age related macular degeneration, Visual impairment and Consumption-archaic term for TB. The involved functions are known as Signal, Regulation, Energy Transfer, Process and Pigment. Zeaxanthin often locates in Chloroplast thylakoids, reaction center, Tissue membrane, PSII associated light-harvesting complex II and Thylakoid Membrane. The associated genes with Zeaxanthin are PRB2 gene, Structural gene, Polypeptides, Genes, Bacterial and Genes, rRNA. The related lipids are Membrane Lipids, Micelles, Fatty Acids, Lipid Peroxides and monogalactosyldiacylglycerol. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Zeaxanthin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Zeaxanthin?

Zeaxanthin is suspected in Dermatitis, Phototoxic, Age related macular degeneration, Cataract, Disintegration, Reflex Epilepsy, Photosensitive, Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Zeaxanthin

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Zeaxanthin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Zeaxanthin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Zeaxanthin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Zeaxanthin?

Related references are published most in these journals:

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What genes are associated with Zeaxanthin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Zeaxanthin?

Knock-out

Knock-out are used in the study 'Zeaxanthin binds to light-harvesting complex stress-related protein to enhance nonphotochemical quenching in Physcomitrella patens.' (Pinnola A et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Zeaxanthin

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Authors Title Published Journal PubMed Link
Akuffo KO et al. Sustained supplementation and monitored response with differing carotenoid formulations in early age-related macular degeneration. 2015 Eye (Lond) pmid:25976647
Fréchette E et al. Zeaxanthin-independent energy quenching and alternative electron sinks cause a decoupling of the relationship between the photochemical reflectance index (PRI) and photosynthesis in an evergreen conifer during spring. 2015 J. Exp. Bot. pmid:26386258
Xu P et al. Molecular insights into Zeaxanthin-dependent quenching in higher plants. 2015 Sci Rep pmid:26323786
Saidi EA et al. The Effect of Zeaxanthin on the Visual Acuity of Zebrafish. 2015 PLoS ONE pmid:26267864
Gerotto C et al. In Vivo Identification of Photosystem II Light Harvesting Complexes Interacting with PHOTOSYSTEM II SUBUNIT S. 2015 Plant Physiol. pmid:26069151
Zhou J et al. Manipulation of the Xanthophyll Cycle Increases Plant Susceptibility to Sclerotinia sclerotiorum. 2015 PLoS Pathog. pmid:25993128
Meyers KJ et al. Joint Associations of Diet, Lifestyle, and Genes with Age-Related Macular Degeneration. 2015 Ophthalmology pmid:26354764
Arteni AA et al. Structure and Conformation of the Carotenoids in Human Retinal Macular Pigment. 2015 PLoS ONE pmid:26313550
Chew EY et al. Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. 2015 JAMA pmid:26305649
Maggio M et al. Relationship between Carotenoids, Retinol, and Estradiol Levels in Older Women. 2015 Nutrients pmid:26251919
Kim JE et al. Effects of egg consumption on carotenoid absorption from co-consumed, raw vegetables. 2015 Am. J. Clin. Nutr. pmid:26016861
Glaser TS et al. The Association of Dietary Lutein plus Zeaxanthin and B Vitamins with Cataracts in the Age-Related Eye Disease Study: AREDS Report No. 37. 2015 Ophthalmology pmid:25972257
Ma L et al. Lutein, Zeaxanthin and Meso-zeaxanthin Supplementation Associated with Macular Pigment Optical Density. 2016 Nutrients pmid:27420092
Gorusupudi A et al. Developmentally Regulated Production of meso-Zeaxanthin in Chicken Retinal Pigment Epithelium/Choroid and Retina. 2016 Invest. Ophthalmol. Vis. Sci. pmid:27082300
Ahrazem O et al. Intron retention and rhythmic diel pattern regulation of carotenoid cleavage dioxygenase 2 during crocetin biosynthesis in saffron. 2016 Plant Mol. Biol. pmid:27071403
You QS et al. REPRODUCIBILITY OF MACULAR PIGMENT OPTICAL DENSITY MEASUREMENT BY TWO-WAVELENGTH AUTOFLUORESCENCE IN A CLINICAL SETTING. 2016 Retina (Philadelphia, Pa.) pmid:26655614
Bernstein PS et al. Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. 2016 Prog Retin Eye Res pmid:26541886
Ahrazem O et al. The carotenoid cleavage dioxygenase CCD2 catalysing the synthesis of crocetin in spring crocuses and saffron is a plastidial enzyme. 2016 New Phytol. pmid:26377696
Matuszyńska A et al. A mathematical model of non-photochemical quenching to study short-term light memory in plants. 2016 Biochim. Biophys. Acta pmid:27620066
Janse VAN Rensburg A and Wenhold F Validity and Reliability of Field Resonance Raman Spectroscopy for Assessing Carotenoid Status. 2016 J. Nutr. Sci. Vitaminol. pmid:27928118
Theelen T et al. Macular fibrosis complicating macular pigment deficient maculopathy in Sjögren-Larsson syndrome. 2016 Acta Ophthalmol pmid:27061911
Stuetz W et al. Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35-74 Years) General Population: A Cross-Sectional Study in Six European Countries. 2016 Nutrients pmid:27706032
GÅ‚Ä…bska D et al. Lycopene, Lutein and Zeaxanthin May Reduce Faecal Blood, Mucus and Pus but not Abdominal Pain in Individuals with Ulcerative Colitis. 2016 Nutrients pmid:27706028
Thomas SE and Harrison EH Mechanisms of selective delivery of xanthophylls to retinal pigment epithelial cells by human lipoproteins. 2016 J. Lipid Res. pmid:27538825
Zheng YF et al. In Vitro Inhibition of Human UDP-Glucuronosyl-Transferase (UGT) Isoforms by Astaxanthin, β-Cryptoxanthin, Canthaxanthin, Lutein, and Zeaxanthin: Prediction of in Vivo Dietary Supplement-Drug Interactions. 2016 Molecules pmid:27529203
Mares J Lutein and Zeaxanthin Isomers in Eye Health and Disease. 2016 Annu. Rev. Nutr. pmid:27431371
Palczewski G et al. Genetic dissection in a mouse model reveals interactions between carotenoids and lipid metabolism. 2016 J. Lipid Res. pmid:27389691
Hammond BR and Renzi-Hammond LM Perspective: A Critical Look at the Ancillary Age-Related Eye Disease Study 2: Nutrition and Cognitive Function Results in Older Individuals with Age-Related Macular Degeneration. 2016 Adv Nutr pmid:27184270
McGill TJ et al. Elevated Fundus Autofluorescence in Monkeys Deficient in Lutein, Zeaxanthin, and Omega-3 Fatty Acids. 2016 Invest. Ophthalmol. Vis. Sci. pmid:27002296
Al-Holou SN et al. The Association of Statin Use with Cataract Progression and Cataract Surgery: The AREDS2 Report Number 8. 2016 Ophthalmology pmid:26686966
Silván JM et al. A protective effect of anthocyanins and xanthophylls on UVB-induced damage in retinal pigment epithelial cells. 2016 Food Funct pmid:26781209
Tuzcu M et al. Lutein and zeaxanthin isomers modulates lipid metabolism and the inflammatory state of retina in obesity-induced high-fat diet rodent model. 2017 BMC Ophthalmol pmid:28738845
Conrady CD et al. Correlations Between Macular, Skin, and Serum Carotenoids. 2017 Invest. Ophthalmol. Vis. Sci. pmid:28728169
Jia YP et al. The Pharmacological Effects of Lutein and Zeaxanthin on Visual Disorders and Cognition Diseases. 2017 Molecules pmid:28425969
Valle-Prieto MB et al. Virgin Olive Oil Enriched with Lutein-Zeaxanthin from Spinacia oleracea. 2017 J Oleo Sci pmid:28413190
Eisenhauer B et al. Lutein and Zeaxanthin-Food Sources, Bioavailability  and Dietary Variety in Age-Related Macular  Degeneration Protection. 2017 Nutrients pmid:28208784
Lakey-Beitia J et al. Anti-amyloid aggregation activity of novel carotenoids: implications for Alzheimer's drug discovery. 2017 Clin Interv Aging pmid:28553090
Nishino A et al. Reaction and Scavenging Mechanism of β-Carotene and Zeaxanthin with Reactive Oxygen Species. 2017 J Oleo Sci pmid:27928140
Jeon S et al. Effect of Carotenoid Supplemented Formula on Carotenoid Bioaccumulation in Tissues of Infant Rhesus Macaques: A Pilot Study Focused on Lutein. 2017 Nutrients pmid:28075370
Ademowo OS et al. Phospholipid oxidation and carotenoid supplementation in Alzheimer's disease patients. 2017 Free Radic. Biol. Med. pmid:28315450
Choi JY et al. Flavobacterium kingsejongi sp. nov., a carotenoid-producing species isolated from Antarctic penguin faeces. 2018 Int. J. Syst. Evol. Microbiol. pmid:29458488
Johnson QR et al. Effects of carotenoids on lipid bilayers. 2018 Phys Chem Chem Phys pmid:29349456