HEXANOIC ACID

HEXANOIC ACID is a lipid of Fatty Acyls (FA) class. Hexanoic acid is associated with abnormalities such as Obesity, Ileoanal Pouches, Ulcerative Colitis, Ulcerative colitis, quiescent and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Binding (Molecular Function), Anabolism, Adjudication, enzyme activity and Process. Hexanoic acid often locates in Membrane, Tissue membrane, Microsomes, Liver, Microsomes and Mitochondria. The associated genes with HEXANOIC ACID are SH2D1A gene, Fusion Protein and MAPK3 gene. The related lipids are hexanoic acid, Fatty Acids, Butyric Acid, Propionate and Palmitates.

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Introduction

To understand associated biological information of HEXANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with HEXANOIC ACID?

HEXANOIC ACID is suspected in Obesity, Ileoanal Pouches, Ulcerative Colitis, Ulcerative colitis, quiescent, Diabetes Mellitus, Non-Insulin-Dependent, Gastroesophageal reflux disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with HEXANOIC ACID

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Alzheimer Disease D000544 76 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Starvation D013217 47 associated lipids
Arthritis D001168 41 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Uremia D014511 33 associated lipids
Plaque, Amyloid D058225 19 associated lipids
Disease Resistance D060467 12 associated lipids
Riboflavin Deficiency D012257 10 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with HEXANOIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with HEXANOIC ACID?

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Location Cross reference Weighted score Related literatures
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What functions are associated with HEXANOIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with HEXANOIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with HEXANOIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with HEXANOIC ACID?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with HEXANOIC ACID

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Authors Title Published Journal PubMed Link
Xie Z et al. An overview of recent development in composite catalysts from porous materials for various reactions and processes. 2010 Int J Mol Sci pmid:20559508
Tokiwa Y et al. Biodegradability of plastics. 2009 Int J Mol Sci pmid:19865515
Narayanan A et al. Anticarcinogenic properties of medium chain fatty acids on human colorectal, skin and breast cancer cells in vitro. 2015 Int J Mol Sci pmid:25749477
García-Robles I et al. Combining hexanoic acid plant priming with Bacillus thuringiensis insecticidal activity against Colorado potato beetle. 2013 Int J Mol Sci pmid:23743826
Zea L et al. Chromatography-olfactometry study of the aroma of fino sherry wines. 2010 Int J Anal Chem pmid:20689702
Oyo-Ita OE et al. Occurrence and sources of triterpenoid methyl ethers and acetates in sediments of the cross-river system, southeast Nigeria. 2010 Int J Anal Chem pmid:20414350
Peyser RD et al. Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia. 2017 Insect Mol. Biol. pmid:28703934
Farine J et al. Production, regeneration and biochemical precursors of the major components of the defensive secretion of Eurycotis floridana (Dictyoptera, polyzosteriinae). 2000 Insect Biochem. Mol. Biol. pmid:10844252
Zahmakiran M and Ozkar S Dimethylammonium hexanoate stabilized rhodium(0) nanoclusters identified as true heterogeneous catalysts with the highest observed activity in the dehydrogenation of dimethylamine-borane. 2009 Inorg Chem pmid:19702246
Larsen B and Hwang J Progesterone interactions with the cervix: translational implications for term and preterm birth. 2011 Infect Dis Obstet Gynecol pmid:22114461
Vitali M et al. Exposure to organic solvents among handicraft car painters: A pilot study in Italy. 2006 Ind Health pmid:16716010
Haeckel R et al. Hydrazonopropionic acids, a new class of hypoglycemic substances. 5. Inhibition of hepatic gluconeogenesis by 2-(3-methylcinnamyl-hydrazono)-propionate in the rat and guinea pig. 1985 Horm. Metab. Res. pmid:3922863
Amlou M et al. Larval tolerance in the Drosophila melanogaster species complex toward the two toxic acids of the D. sechellia host plant. 1998 Hereditas pmid:9868925
Walden HR et al. Xenobiotic incorporation into pyruvate dehydrogenase complex can occur via the exogenous lipoylation pathway. 2008 Hepatology pmid:19003917
De Preter V et al. Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD. 2015 Gut pmid:24811995
Gu R et al. [Omega-mercaptohexanoic acid self-assemble-modified gold electrode and its catalytic property for redox reaction of chlorophylls]. 1999 Guang Pu Xue Yu Guang Pu Fen Xi pmid:15818915
van Bakel H et al. The draft genome and transcriptome of Cannabis sativa. 2011 Genome Biol. pmid:22014239
Higa I and Fuyama Y Genetics of food preference in Drosophila sechellia. I. Responses to food attractants. 1993 Genetica pmid:8224853
Fickers P et al. Identification and characterisation of LIP7 and LIP8 genes encoding two extracellular triacylglycerol lipases in the yeast Yarrowia lipolytica. 2005 Fungal Genet. Biol. pmid:15707847
Maggio-Hall LA et al. A single acyl-CoA dehydrogenase is required for catabolism of isoleucine, valine and short-chain fatty acids in Aspergillus nidulans. 2008 Fungal Genet. Biol. pmid:17656140
Uchida N and Mainen ZF Odor concentration invariance by chemical ratio coding. 2007 Front Syst Neurosci pmid:18958244
Sandoz JC Behavioral and neurophysiological study of olfactory perception and learning in honeybees. 2011 Front Syst Neurosci pmid:22163215
Mathys J et al. Genome-Wide Characterization of ISR Induced in Arabidopsis thaliana by Trichoderma hamatum T382 Against Botrytis cinerea Infection. 2012 Front Plant Sci pmid:22661981
Burke CJ and Tobler PN Coding of reward probability and risk by single neurons in animals. 2011 Front Neurosci pmid:22013410
Fichtel K et al. Isolation of sulfate-reducing bacteria from sediments above the deep-subseafloor aquifer. 2012 Front Microbiol pmid:22363336
Kulichevskaya IS et al. Telmatocola sphagniphila gen. nov., sp. nov., a novel dendriform planctomycete from northern wetlands. 2012 Front Microbiol pmid:22529844
Misra S et al. Statistical approach to study the interactive effects of process parameters for enhanced xylitol production by Candida tropicalis and its potential for the synthesis of xylitol monoesters. 2013 Food Sci Technol Int pmid:23733812
Ohlsson L Dairy products and plasma cholesterol levels. 2010 Food Nutr Res pmid:20806084
Huang Y et al. Evaluation of the efficacy of four weak acids as antifungal preservatives in low-acid intermediate moisture model food systems. 2010 Food Microbiol. pmid:19913689
Bayard M et al. Free fatty acids and their esters modulate isothermal crystallization of anhydrous milk fat. 2017 Food Chem pmid:27719901
Raffo A et al. Quantification of allyl hexanoate in pineapple beverages and yogurts as a case study to characterise a source of uncertainty in dietary exposure assessment to flavouring substances. 2012 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:22043838
Sánchez-Ribas I et al. Differential metabolic profiling of non-pure trisomy 21 human preimplantation embryos. 2012 Fertil. Steril. pmid:22959456
Suzuki Y et al. A novel thermostable esterase from the thermoacidophilic archaeon Sulfolobus tokodaii strain 7. 2004 FEMS Microbiol. Lett. pmid:15212797
Kendall MM et al. Butyrate- and propionate-degrading syntrophs from permanently cold marine sediments in Skan Bay, Alaska, and description of Algorimarina butyrica gen. nov., sp. nov. 2006 FEMS Microbiol. Lett. pmid:16907746
Royter M et al. Thermostable lipases from the extreme thermophilic anaerobic bacteria Thermoanaerobacter thermohydrosulfuricus SOL1 and Caldanaerobacter subterraneus subsp. tengcongensis. 2009 Extremophiles pmid:19579003
Sorokin DY et al. Propionate and butyrate dependent bacterial sulfate reduction at extremely haloalkaline conditions and description of Desulfobotulus alkaliphilus sp. nov. 2010 Extremophiles pmid:19888546
Rabinowitz JL and Bassett DJ Effect of 2 ppm ozone exposure on rat lung lipid fatty acids. 1988 Exp. Lung Res. pmid:3208714
Oku Y et al. Meriones meridianus and Lagurus lagurus as alternative definitive hosts of Echinococcus multilocularis and E. granulosus. 2002 Exp. Anim. pmid:11871149
Jeon JH et al. Novel lipolytic enzymes identified from metagenomic library of deep-sea sediment. 2011 Evid Based Complement Alternat Med pmid:21845199
Zakaria ZA et al. Hepatoprotective activity of dried- and fermented-processed virgin coconut oil. 2011 Evid Based Complement Alternat Med pmid:21318140
Datta HS et al. Theories and management of aging: modern and ayurveda perspectives. 2011 Evid Based Complement Alternat Med pmid:19233879
Chashoo G et al. Potentiation of the antitumor effect of 11-keto-β-boswellic acid by its 3-α-hexanoyloxy derivative. 2011 Eur. J. Pharmacol. pmid:21821018
Ushigome F et al. Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo). 2001 Eur. J. Pharmacol. pmid:11334847
Han B et al. The opposing effects of endothelin-1 and C-type natriuretic peptide on apoptosis of neonatal rat cardiac myocytes. 2003 Eur. J. Pharmacol. pmid:12909191
Ghaninia M et al. Functional classification and central nervous projections of olfactory receptor neurons housed in antennal trichoid sensilla of female yellow fever mosquitoes, Aedes aegypti. 2007 Eur. J. Neurosci. pmid:17880395
Bruins M et al. Device-independent, real-time identification of bacterial pathogens with a metal oxide-based olfactory sensor. 2009 Eur. J. Clin. Microbiol. Infect. Dis. pmid:19190942
Wanten GJ et al. Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length. 2002 Eur. J. Clin. Invest. pmid:11952815
Marshall MO and Knudsen J Biosynthesis of triacylglycerols containing short-chain fatty acids in lactating cow mammary gland. Activity of diacylglycerol acyltransferase towards short-chain acyl-CoA esters. 1977 Eur. J. Biochem. pmid:598368
Berry MN et al. Compartmentation of fatty acid oxidation in liver cells. 1983 Eur. J. Biochem. pmid:6832142
Sundqvist KE et al. Metabolic effects of propionate, hexanoate and propionylcarnitine in normoxia, ischaemia and reperfusion. Does an anaplerotic substrate protect the ischaemic myocardium? 1994 Eur. Heart J. pmid:8070485
Fischer W et al. Transport of valproate at intestinal epithelial (Caco-2) and brain endothelial (RBE4) cells: mechanism and substrate specificity. 2008 Eur J Pharm Biopharm pmid:18577448
Jeon BS et al. In situ extractive fermentation for the production of hexanoic acid from galactitol by Clostridium sp. BS-1. 2013 Enzyme Microb. Technol. pmid:23830453
Drzewicz P et al. Impact of peroxydisulfate in the presence of zero valent iron on the oxidation of cyclohexanoic acid and naphthenic acids from oil sands process-affected water. 2012 Environ. Sci. Technol. pmid:22799739
Harroff LA et al. Inactivation of Ascaris Eggs in Human Fecal Material Through In Situ Production of Carboxylic Acids. 2017 Environ. Sci. Technol. pmid:28759229
Ge S et al. Long-Term n-Caproic Acid Production from Yeast-Fermentation Beer in an Anaerobic Bioreactor with Continuous Product Extraction. 2015 Environ. Sci. Technol. pmid:25941741
Kotsyurbenko OR et al. Acetoclastic and hydrogenotrophic methane production and methanogenic populations in an acidic West-Siberian peat bog. 2004 Environ. Microbiol. pmid:15479249
Metje M and Frenzel P Methanogenesis and methanogenic pathways in a peat from subarctic permafrost. 2007 Environ. Microbiol. pmid:17359267
Sánchez-Otero MG et al. Enzymatic reactions and synthesis of n-butyl caproate: esterification, transesterification and aminolysis using a recombinant lipase from Geobacillus thermoleovorans CCR11. 2010 Environ Technol pmid:20718292
Fang HH et al. Effects of Mo(VI) on phototrophic hydrogen production by Rhodobacter sphaeroides. Environ Technol pmid:21970170
Hutton JC et al. Similarities in the stimulus-secretion coupling mechanisms of glucose- and 2-keto acid-induced insulin release. 1980 Endocrinology pmid:6985583
Bruno JF and Berelowitz M Covalent labeling of the somatostatin receptor in rat anterior pituitary membranes. 1989 Endocrinology pmid:2563243
Nishi Y et al. Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin. 2005 Endocrinology pmid:15677766
Renner S et al. Isotachophoretic analysis of the dihydrofolate reductase reaction in the presence of methotrexate and ascorbic acid. 2000 Electrophoresis pmid:11001289
Shim J et al. A method to determine quasi-steady state in constant voltage mode isotachophoresis. 2011 Electrophoresis pmid:21449067
Yamamoto A et al. Enhanced permeability of phenylalanyl-glycine (Phe-Gly) across the intestinal membranes by chemical modification with various fatty acids. 2003 Drug Metab. Pharmacokinet. pmid:15618716
Bowersox SS et al. Metabolism and pharmacokinetics of naronapride (ATI-7505), a serotonin 5-HT(4) receptor agonist for gastrointestinal motility disorders. 2011 Drug Metab. Dispos. pmid:21447732
Umehara K et al. Oxidative cleavage of the octyl side chain of 1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045) in rat and dog liver preparations. 2000 Drug Metab. Dispos. pmid:10901696
Wen MM et al. Systemic enhancement of papaverine transdermal gel for erectile dysfunction. 2012 Drug Dev Ind Pharm pmid:22080854
Wang L et al. Elevated fecal short chain fatty acid and ammonia concentrations in children with autism spectrum disorder. 2012 Dig. Dis. Sci. pmid:22535281
Carnahan AM et al. Enzymatic characterization of three aeromonas species using API Peptidase, API "Osidase," and API Esterase test kits. 1988 Diagn. Microbiol. Infect. Dis. pmid:3072150
Tan CP et al. Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice. 2008 Diabetes pmid:18477808
Berhanu P and Olefsky JM Photoaffinity labeling of insulin receptors in viable cultured human lymphocytes. Demonstration of receptor shedding and degradation. 1982 Diabetes pmid:7152133
Miura M et al. Allergic contact cheilitis caused by ditrimethylolpropane triethylhexanoate in a lipstick. 2011 Contact Derm. pmid:21480923
Juárez MP and Napolitano R Effects of organic acids on lipid synthesis and ecdysis in Triatoma infestans eggs. 2000 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:10904863
Wright JM et al. The effect of side chain structure on the biochemical and therapeutic properties of intra-articular dexamethasone 21-esters. 1986 Oct-Dec Clin. Exp. Rheumatol. pmid:3791716
Gregersen N et al. Non-ketotic C6-C10-dicarboxylic aciduria: biochemical investigations of two cases. 1980 Clin. Chim. Acta pmid:6892795
Beckett GJ et al. Investigations into the choice of immunogen, ligand, antiserum and assay conditions for the radioimmunoassay of conjugated cholic acid. 1978 Clin. Chim. Acta pmid:29725
Kølvraa S et al. Excretion of short-chain N-acylglycines in the urine of a patient with D-glyceric acidemia. 1980 Clin. Chim. Acta pmid:7408214
Jakobs C et al. Hydroxy acid metabolites of branched-chain amino acids in amniotic fluid. 1984 Clin. Chim. Acta pmid:6467607
Xue R et al. Gas chromatography/mass spectrometry screening of serum metabolomic biomarkers in hepatitis B virus infected cirrhosis patients. 2009 Clin. Chem. Lab. Med. pmid:19676142
Yuan J et al. Studies on caproic acid fermentation using immobilized cells. 1993 Chin. J. Biotechnol. pmid:8199321
van Rossum G et al. Liquefaction of lignocellulosic biomass: solvent, process parameter, and recycle oil screening. 2014 ChemSusChem pmid:24265195
Himanen M et al. Phytotoxicity of low-weight carboxylic acids. 2012 Chemosphere pmid:22440635
Gunschera J et al. Surface-catalysed reactions on pollutant-removing building products for indoor use. 2009 Chemosphere pmid:19181362
Lin YC et al. Effects of water washing on removing organic residues in bottom ashes of municipal solid waste incinerators. 2011 Chemosphere pmid:21112610
Carvalho MF et al. Biological treatment of a contaminated gaseous emission from a leather industry in a suspended-growth bioreactor. 2009 Chemosphere pmid:18990430
Mu Y et al. The role of pH in the fermentative H2 production from an acidogenic granule-based reactor. 2006 Chemosphere pmid:16466779
Zhang Y et al. Application of UV-irradiated Fe(III)-nitrilotriacetic acid (UV-Fe(III)NTA) and UV-NTA-Fenton systems to degrade model and natural occurring naphthenic acids. 2017 Chemosphere pmid:28388447
Chi FH et al. Quick determination of malodor-causing fatty acids in manure by capillary electrophoresis. 2005 Chemosphere pmid:16018897
Tietze LF et al. Synthesis of a novel ether-bridged GM3-lactone analogue as a target for an antibody-based cancer therapy. 2000 Chemistry pmid:10985728
Coll C et al. Fatty acid carboxylate- and anionic surfactant-controlled delivery systems that use mesoporous silica supports. 2010 Chemistry pmid:20645326
Groegel DB et al. A new fluorescent PET probe for hydrogen peroxide and its use in enzymatic assays for L-lactate and D-glucose. 2011 Chembiochem pmid:22076816
Ma Y et al. Catalytic relationships between type I and type II iterative polyketide synthases: The Aspergillus parasiticus norsolorinic acid synthase. 2006 Chembiochem pmid:17086560
Bisulco S and Slotnick B Olfactory discrimination of short chain fatty acids in rats with large bilateral lesions of the olfactory bulbs. 2003 Chem. Senses pmid:12826532
Barrozo RB and Lazzari CR Orientation behaviour of the blood-sucking bug triatoma infestans to short-chain fatty acids: synergistic effect of L-lactic acid and carbon dioxide. 2004 Chem. Senses pmid:15574819
Yang S et al. Diacetyl/l-Xylulose Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells. 2017 Chem. Res. Toxicol. pmid:28595002
Slotboom AJ et al. Application of enantiomeric 2-sn-phosphatidylcholines in interfacial enzyme kinetics of lipolysis. 1976 Chem. Phys. Lipids pmid:991374
Xu J et al. In-line and selective phase separation of medium-chain carboxylic acids using membrane electrolysis. 2015 Chem. Commun. (Camb.) pmid:25792085
BÅ‚aszczyk A et al. Genotoxic and antioxidant activities of ethoxyquin salts evaluated by the comet assay. 2006 Chem. Biol. Interact. pmid:16959229
Watanabe CM and Townsend CA Initial characterization of a type I fatty acid synthase and polyketide synthase multienzyme complex NorS in the biosynthesis of aflatoxin B(1). 2002 Chem. Biol. pmid:12323372