| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uremia | D014511 | 33 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Leukemia, Erythroblastic, Acute | D004915 | 41 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Riboflavin Deficiency | D012257 | 10 associated lipids |
HEXANOIC ACID
HEXANOIC ACID is a lipid of Fatty Acyls (FA) class. Hexanoic acid is associated with abnormalities such as Obesity, Ileoanal Pouches, Ulcerative Colitis, Ulcerative colitis, quiescent and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Binding (Molecular Function), Anabolism, Adjudication, enzyme activity and Process. Hexanoic acid often locates in Membrane, Tissue membrane, Microsomes, Liver, Microsomes and Mitochondria. The associated genes with HEXANOIC ACID are SH2D1A gene, Fusion Protein and MAPK3 gene. The related lipids are hexanoic acid, Fatty Acids, Butyric Acid, Propionate and Palmitates.
Cross Reference
Introduction
To understand associated biological information of HEXANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with HEXANOIC ACID?
HEXANOIC ACID is suspected in Obesity, Ileoanal Pouches, Ulcerative Colitis, Ulcerative colitis, quiescent, Diabetes Mellitus, Non-Insulin-Dependent, Gastroesophageal reflux disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with HEXANOIC ACID
PubChem Associated disorders and diseases
What pathways are associated with HEXANOIC ACID
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with HEXANOIC ACID?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Drug Metab. Dispos. (2)
- J. Biol. Chem. (2)
- Am. J. Physiol. Gastrointest. Liver Physiol. (1)
- Others (1)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with HEXANOIC ACID?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with HEXANOIC ACID?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with HEXANOIC ACID?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with HEXANOIC ACID?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with HEXANOIC ACID
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Thomas JM et al. | Molecular sieve catalysts for the regioselective and shape- selective oxyfunctionalization of alkanes in air. | 2001 | Acc. Chem. Res. | pmid:11263877 |
| Cao W et al. | Self-assembly of amphiphilic janus particles into monolayer capsules for enhanced enzyme catalysis in organic media. | 2015 | ACS Appl Mater Interfaces | pmid:25478712 |
| Peng XC et al. | 1-(3,4-Dihy-droxy-phen-yl)hexan-1-one. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21587942 |
| Rieth T et al. | 5-Pentyl-1H-tetra-zole. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21522663 |
| Xia JH et al. | {2-[(3,5-Dichloro-2-oxidobenzyl-idene)amino-κN,O]-3-methyl-penta-noato-κO}(N,N'-dimethyl-formamide-κO)copper(II). | 2008 | Acta Crystallogr Sect E Struct Rep Online | pmid:21202205 |
| Taylor RA and Ellis HA | Anhydrous polymeric zinc(II) penta-noate. | 2008 | Acta Crystallogr Sect E Struct Rep Online | pmid:21202761 |
| Ouahrouch A et al. | 4-{4-[(4-Oxoquinazolin-3-yl)meth-yl]-1H-1,2,3-triazol-1-yl}butyl acetate. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:22199711 |
| Sudo K et al. | Anti-androgen TSAA-291. IV. Effects of the anti-androgen TSAA-291 (16 beta-ethyl-17 beta-hydroxy-4-oestren-3-one) on the secretion of gonadotrophins. | 1979 | Acta Endocrinol Suppl (Copenh) | pmid:294107 |
| Bellmann O et al. | In vitro studies on enzymatic cleavage of steroid esters in the female organism. | 1976 | Acta Endocrinol. | pmid:130782 |
| Talbot A | Measurement of adenosine triphosphate and some other metabolites in blood cells by isotachophoresis. I. Preparative technique and enzymatic confirmation. | 1982 | Acta Med. Okayama | pmid:7180574 |
| Papierkowski A et al. | Monocarboxylic short-chain fatty acids C2-C6 in serum of obese children. | 1975 | Acta Paediatr Acad Sci Hung | pmid:1224976 |
| LISNELL A and MELLGREN J | Effect of heparin, protamine, dicoumarol, streptokinase and epsilon-amino-n-caproic acid on the growth of human cells in vitro. | 1963 | Acta Pathol Microbiol Scand | pmid:13930893 |
| Pagliaro P et al. | Fatty acids are important for the Frank-Starling mechanism and Gregg effect but not for catecholamine response in isolated rat hearts. | 2002 | Acta Physiol. Scand. | pmid:12392496 |
| Kurzawa M et al. | Indirect determination of neomycin trisulphate as sulphate by column coupling capillary isotachophoresis. | 2005 May-Jun | Acta Pol Pharm | pmid:16193807 |
| Hrbek J et al. | Effect of the application of epsilon-aminocaproic acid and n-caproic acid on biogenic amine levels in female rat brain. | 1986 | Acta Univ Palacki Olomuc Fac Med | pmid:2951978 |
| Harkness RA | Lesch-Nyhan syndrome: reduced amino acid concentrations in CSF and brain. | 1989 | Adv. Exp. Med. Biol. | pmid:2624185 |
| Handler JA and Thurman RG | Rates of H2O2 generation from peroxisomal beta-oxidation are sufficient to account for fatty acid-stimulated ethanol metabolism in perfused rat liver. | 1987 Mar-Apr | Alcohol | pmid:3580135 |
| CURTIS WB and CAPRON EB | Self re-referral in an adolescent girl workshop, 1950. | 1951 | Am J Orthopsychiatry | pmid:14857137 |
| Madan E and Slifkin M | Stool caproic acid for screening of Clostridium difficile. | 1988 | Am. J. Clin. Pathol. | pmid:3354506 |
| Manuck TA et al. | Progesterone receptor polymorphisms and clinical response to 17-alpha-hydroxyprogesterone caproate. | 2011 | Am. J. Obstet. Gynecol. | pmid:21600550 |
| Hemauer SJ et al. | Transplacental transfer and metabolism of 17-alpha-hydroxyprogesterone caproate. | 2008 | Am. J. Obstet. Gynecol. | pmid:18674659 |
| Yan R et al. | The effect of esterases on 17alpha-hydroxyprogesterone caproate. | 2008 | Am. J. Obstet. Gynecol. | pmid:17936237 |
| Foglia LM et al. | Intramuscular 17α-hydroxyprogesterone caproate administration attenuates immunoresponsiveness of maternal peripheral blood mononuclear cells. | 2010 | Am. J. Obstet. Gynecol. | pmid:20810098 |
| Spong CY et al. | Progesterone for prevention of recurrent preterm birth: impact of gestational age at previous delivery. | 2005 | Am. J. Obstet. Gynecol. | pmid:16157124 |
| Adams SH and Odle J | Acetogenesis does not replace ketogenesis in fasting piglets infused with hexanoate. | 1998 | Am. J. Physiol. | pmid:9611143 |
| Burkhoff D et al. | Influence of metabolic substrate on rat heart function and metabolism at different coronary flows. | 1991 | Am. J. Physiol. | pmid:1887921 |
| Kvietys PR et al. | Contribution of bile to postprandial intestinal hyperemia. | 1980 | Am. J. Physiol. | pmid:7377305 |
| Madden MC et al. | Acylcarnitine accumulation does not correlate with reperfusion recovery in palmitate-perfused rat hearts. | 1995 | Am. J. Physiol. | pmid:7611501 |
| Jørgensen J and Mortensen PB | Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11447021 |
| Running CA and Mattes RD | Different oral sensitivities to and sensations of short-, medium-, and long-chain fatty acids in humans. | 2014 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:24924750 |
| Ray J et al. | Long-chain fatty acids increase basal metabolism and depolarize mitochondria in cardiac muscle cells. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11893587 |
| Suh HN et al. | Linoleic acid stimulates gluconeogenesis via Ca2+/PLC, cPLA2, and PPAR pathways through GPR40 in primary cultured chicken hepatocytes. | 2008 | Am. J. Physiol., Cell Physiol. | pmid:18842827 |
| Barrera R | Spatial stability of adult Aedes aegypti populations. | 2011 | Am. J. Trop. Med. Hyg. | pmid:22144449 |
| Mark JJ et al. | Comparison of the performance characteristics of two tubular contactless conductivity detectors with different dimensions and application in conjunction with HPLC. | 2011 | Anal Bioanal Chem | pmid:21761108 |
| Yu X et al. | A new direct Fourier transform infrared analysis of free fatty acids in edible oils using spectral reconstitution. | 2011 | Anal Bioanal Chem | pmid:21556753 |
| Zhu L et al. | Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry. | 2010 | Anal Bioanal Chem | pmid:20644917 |
| Eggink M et al. | Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA. | 2010 | Anal Bioanal Chem | pmid:20238107 |
| Aota A et al. | Flow velocity profile of micro counter-current flows. | 2007 | Anal Sci | pmid:17297221 |
| Honoré B and Brodersen R | Detection of carrier heterogeneity by rate of ligand dialysis: medium-chain fatty acid interaction with human serum albumin and competition with chloride. | 1988 | Anal. Biochem. | pmid:3407921 |
| McGrath LT et al. | Gas-liquid chromatographic analysis of volatile short chain fatty acids in fecal samples as pentafluorobenzyl esters. | 1992 | Anal. Biochem. | pmid:1481974 |
| Olivares A et al. | Selected ion flow tube-mass spectrometry for absolute quantification of aroma compounds in the headspace of dry fermented sausages. | 2010 | Anal. Chem. | pmid:20518472 |
| Li CY et al. | A fluorescent chemosensor for Hg2+ based on naphthalimide derivative by fluorescence enhancement in aqueous solution. | 2012 | Anal. Chim. Acta | pmid:22304823 |
| MÃka J et al. | A thin-layer contactless conductivity cell for detection in flowing liquids. | 2009 | Anal. Chim. Acta | pmid:19720191 |
| Riazanskaia S et al. | The analytical utility of thermally desorbed polydimethylsilicone membranes for in-vivo sampling of volatile organic compounds in and on human skin. | 2008 | Analyst | pmid:18645643 |
| Morio M et al. | Quantitative analysis of trifluoroacetate in the urine and blood by isotachophoresis. | 1980 | Anesthesiology | pmid:7386909 |
| Kwak HI et al. | Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation. | 2012 | Angiogenesis | pmid:22407449 |
| Røjen BA et al. | Urea and short-chain fatty acids metabolism in Holstein cows fed a low-nitrogen grass-based diet. | 2008 | Animal | pmid:22443564 |
| Sakiyama Y et al. | Evaluation of the brain uptake properties of [1-11C]labeled hexanoate in anesthetized cats by means of positron emission tomography. | 1996 | Ann Nucl Med | pmid:8883717 |
| Ishiwata K et al. | Synthesis and preliminary evaluation of [1-11C]hexanoate as a PET tracer of fatty acid metabolism. | 1995 | Ann Nucl Med | pmid:7779532 |
| Ishiwata K et al. | A brain uptake study of [1-(11)C]hexanoate in the mouse: the effect of hypoxia, starvation and substrate competition. | 1996 | Ann Nucl Med | pmid:8800460 |
| Caldwell R and Challenger H | A capillary column gas-chromatographic method for the identification of drugs of abuse in urine samples. | 1989 | Ann. Clin. Biochem. | pmid:2817754 |
| Germain P et al. | [delta 1-steroid-dehydrogenase biosynthesis and androsta-4-ene-3,17-dione degradation by "Nocardia restricta" (author's transl)]. | 1981 May-Jun | Ann. Microbiol. (Paris) | pmid:7294608 |
| Januszewski AS et al. | Lipid-derived modifications of plasma proteins in experimental and human diabetes. | 2005 | Ann. N. Y. Acad. Sci. | pmid:16037262 |
| Borenstein DG et al. | Gas-liquid chromatographic analysis of synovial fluid: volatile short-chain fatty acids in septic arthritis. | 1983 | Ann. Rheum. Dis. | pmid:6882030 |
| Brook I et al. | Abnormalities in synovial fluid of patients with septic arthritis detected by gas-liquid chromatography. | 1980 | Ann. Rheum. Dis. | pmid:7387221 |
| Medvedeva VI et al. | [Distribution of oleandomycin between the native broth and butylacetate depending on the biosynthesis conditions]. | 1978 | Antibiotiki | pmid:31834 |
| Torgovanova TV et al. | [Effect of the quality of regenerated butanol on the process of producing the potassium salt of benzylpenicillin]. | 1981 | Antibiotiki | pmid:7294747 |
| Teixeira V et al. | The Effect of A Hexanoic Acid Linker Insertion on the Pharmacokinetics and Tumor Targeting Properties of the Melanoma Imaging Agent 99mTc-HYNIC-cycMSH. | 2017 | Anticancer Agents Med Chem | pmid:27924732 |
| Kabara JJ et al. | Fatty acids and derivatives as antimicrobial agents. | 1972 | Antimicrob. Agents Chemother. | pmid:4670656 |
| Mendonça Ade L et al. | Antimicrobial activities of components of the glandular secretions of leaf cutting ants of the genus Atta. | 2009 | Antonie Van Leeuwenhoek | pmid:19214771 |
| Kang HO et al. | Cometabolic biosynthesis of copolyesters consisting of 3-hydroxyvalerate and medium-chain-length 3-hydroxyalkanoates by Pseudomonas sp. DSY-82. | 2001 | Antonie Van Leeuwenhoek | pmid:11759051 |
| Green TR and Popa R | Turnover of carbohydrate-rich vegetal matter during microaerobic composting and after amendment in soil. | 2011 | Appl. Biochem. Biotechnol. | pmid:21537893 |
| Guo YJ et al. | Inhibitory effects of fatty acids on the activity of mushroom tyrosinase. | 2010 | Appl. Biochem. Biotechnol. | pmid:20544305 |
| Choi K et al. | In situ biphasic extractive fermentation for hexanoic acid production from sucrose by Megasphaera elsdenii NCIMB 702410. | 2013 | Appl. Biochem. Biotechnol. | pmid:23754557 |
| Šalić A et al. | Bioproduction of food additives hexanal and hexanoic acid in a microreactor. | 2013 | Appl. Biochem. Biotechnol. | pmid:24043452 |
| Kim JK et al. | Mass production of methane from food wastes with concomitant wastewater treatment. | 2002 | Appl. Biochem. Biotechnol. | pmid:12018299 |
| Zhang K et al. | Regulation of the Docosapentaenoic Acid/Docosahexaenoic Acid Ratio (DPA/DHA Ratio) in Schizochytrium limacinum B4D1. | 2017 | Appl. Biochem. Biotechnol. | pmid:27832512 |
| Butkus MA et al. | Inactivation of Ascaris suum by short-chain fatty acids. | 2011 | Appl. Environ. Microbiol. | pmid:21057018 |
| Paczkowski S and Schütz S | Post-mortem volatiles of vertebrate tissue. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21720824 |
| Wang HH et al. | Biosynthesis of polyhydroxyalkanoate homopolymers by Pseudomonas putida. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21046374 |
| Jin J et al. | Purification, characterization, and cloning of a bifunctional molybdoenzyme with hydratase and alcohol dehydrogenase activity. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21120472 |
| Kim HS et al. | Characterization of a biosurfactant, mannosylerythritol lipid produced from Candida sp. SY16. | 1999 | Appl. Microbiol. Biotechnol. | pmid:10570818 |
| Thumarat U et al. | Biochemical and genetic analysis of a cutinase-type polyesterase from a thermophilic Thermobifida alba AHK119. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22183084 |
| Niewerth H et al. | Synthesis and biotransformation of 2-alkyl-4(1H)-quinolones by recombinant Pseudomonas putida KT2440. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21670979 |
| Zhang J et al. | Induction of hexanol dehydrogenase in Geotrichum spp. by the addition of hexanol. | 2013 | Appl. Microbiol. Biotechnol. | pmid:22821438 |
| Liu P et al. | Membrane stress caused by octanoic acid in Saccharomyces cerevisiae. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23435986 |
| Thrash JC et al. | Description of the novel perchlorate-reducing bacteria Dechlorobacter hydrogenophilus gen. nov., sp. nov.and Propionivibrio militaris, sp. nov. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19921177 |
| Campoy S et al. | Characterization of an hyperpigmenting mutant of Monascus purpureus IB1: identification of two novel pigment chemical structures. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16151799 |
| Jeon BS et al. | Production of hexanoic acid from D-galactitol by a newly isolated Clostridium sp. BS-1. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20721546 |
| Mikulska J et al. | Human placental Fc gamma receptor. Studies on affinity labeling of the receptor with IgG. | 1989 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:2517911 |
| Wilkes H et al. | Anaerobic degradation of n-hexane in a denitrifying bacterium: further degradation of the initial intermediate (1-methylpentyl)succinate via C-skeleton rearrangement. | 2002 | Arch. Microbiol. | pmid:11907679 |
| Huang CB et al. | Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms. | 2011 | Arch. Oral Biol. | pmid:21333271 |
| Cao SL et al. | A novel nasal delivery system of a Chinese traditional medicine, Radix Bupleuri, based on the concept of ion-activated in situ gel. | 2007 | Arch. Pharm. Res. | pmid:17879756 |
| Zahlsen K et al. | Oral intake of a toluene-containing thinner. Effects and headspace gas chromatographic analytical diagnosis. | 1985 | Arch. Toxicol. Suppl. | pmid:3868371 |
| Reckers R | [Clinical trial of fluocortin butylester in a double-blind contralateral comparison versus fluocortolone and hydrocortisone acetate (author's transl)]. | 1977 | Arzneimittelforschung | pmid:341901 |
| Amlou M et al. | Genetic analysis of Drosophila sechellia specialization: oviposition behavior toward the major aliphatic acids of its host plant. | 1998 | Behav. Genet. | pmid:9926614 |
| Binsl TW et al. | Measuring non-steady-state metabolic fluxes in starch-converting faecal microbiota in vitro. | 2010 | Benef Microbes | pmid:21831778 |
| Kato Y et al. | Preparation of a monoclonal antibody to N(epsilon)-(Hexanonyl)lysine: application to the evaluation of protective effects of flavonoid supplementation against exercise-induced oxidative stress in rat skeletal muscle. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10913348 |
| Handler JA and Thurman RG | Fatty acid-dependent ethanol metabolism. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2934065 |
| Bjorge SM and Baillie TA | Inhibition of medium-chain fatty acid beta-oxidation in vitro by valproic acid and its unsaturated metabolite, 2-n-propyl-4-pentenoic acid. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3933498 |
| Anderson P and Nagler C | Photoaffinity labeling of an interferon-gamma receptor on the surface of cultured fibroblasts. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6329186 |
| Dynnik VV and Djafarov RH | Regulation of the tricarboxylic acid cycle and beta-oxidation by excess substrates. | 1986 | Biochem. Int. | pmid:3741443 |
| Young PR and Briedis AV | Purification and kinetic mechanism of the major glutathione S-transferase from bovine brain. | 1989 | Biochem. J. | pmid:2930465 |
| LAURYSSENS M et al. | Incorporation of sodium [1-14C]hexanoate and sodium hydrogen [14C]carbonate into milk constituents by the perfused cow's udder. | 1959 | Biochem. J. | pmid:13853598 |
| Ludtmann MH et al. | Nrf2 affects the efficiency of mitochondrial fatty acid oxidation. | 2014 | Biochem. J. | pmid:24206218 |
| Allen AK et al. | Purification of the glycoprotein lectin from the broad bean (Vicia faba) and a comparison of its properties with lectins of similar specificity. | 1976 | Biochem. J. | pmid:938471 |
| Carey EM and Dils R | The pattern of fatty acid synthesis in lactating rabbit mammary gland studied in vivo. | 1972 | Biochem. J. | pmid:4672462 |
| Chase JF and Tubbs PK | Specific inhibition of mitochondrial fatty acid oxidation by 2-bromopalmitate and its coenzyme A and carnitine esters. | 1972 | Biochem. J. | pmid:4646779 |
| Oh MH et al. | Calcium/calmodulin inhibition of the Arabidopsis BRASSINOSTEROID-INSENSITIVE 1 receptor kinase provides a possible link between calcium and brassinosteroid signalling. | 2012 | Biochem. J. | pmid:22309147 |