HEXANOIC ACID

HEXANOIC ACID is a lipid of Fatty Acyls (FA) class. Hexanoic acid is associated with abnormalities such as Obesity, Ileoanal Pouches, Ulcerative Colitis, Ulcerative colitis, quiescent and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Binding (Molecular Function), Anabolism, Adjudication, enzyme activity and Process. Hexanoic acid often locates in Membrane, Tissue membrane, Microsomes, Liver, Microsomes and Mitochondria. The associated genes with HEXANOIC ACID are SH2D1A gene, Fusion Protein and MAPK3 gene. The related lipids are hexanoic acid, Fatty Acids, Butyric Acid, Propionate and Palmitates.

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Introduction

To understand associated biological information of HEXANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with HEXANOIC ACID?

HEXANOIC ACID is suspected in Obesity, Ileoanal Pouches, Ulcerative Colitis, Ulcerative colitis, quiescent, Diabetes Mellitus, Non-Insulin-Dependent, Gastroesophageal reflux disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with HEXANOIC ACID

MeSH term MeSH ID Detail
Uremia D014511 33 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Arthritis D001168 41 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Alzheimer Disease D000544 76 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Clostridium Infections D003015 5 associated lipids
Starvation D013217 47 associated lipids
Riboflavin Deficiency D012257 10 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with HEXANOIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with HEXANOIC ACID?

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What functions are associated with HEXANOIC ACID?


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Function Cross reference Weighted score Related literatures

What lipids are associated with HEXANOIC ACID?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with HEXANOIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with HEXANOIC ACID?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with HEXANOIC ACID

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Authors Title Published Journal PubMed Link
Amlou M et al. Genetic analysis of Drosophila sechellia specialization: oviposition behavior toward the major aliphatic acids of its host plant. 1998 Behav. Genet. pmid:9926614
Slotboom AJ et al. Application of enantiomeric 2-sn-phosphatidylcholines in interfacial enzyme kinetics of lipolysis. 1976 Chem. Phys. Lipids pmid:991374
Matsuki H et al. Specific and non-specific binding of long-chain fatty acids to firefly luciferase: cutoff at octanoate. 1999 Biochim. Biophys. Acta pmid:9878713
Amlou M et al. Larval tolerance in the Drosophila melanogaster species complex toward the two toxic acids of the D. sechellia host plant. 1998 Hereditas pmid:9868925
Mollica MP et al. Oxygen consumption and biosynthetic function in perfused liver from rats at different stages of development. 1998 Cell. Mol. Life Sci. pmid:9849619
Wilkening G et al. Lysosomal degradation on vesicular membrane surfaces. Enhanced glucosylceramide degradation by lysosomal anionic lipids and activators. 1998 J. Biol. Chem. pmid:9804787
Thurmond DC et al. Regulation of the action of steroid/thyroid hormone receptors by medium-chain fatty acids. 1998 J. Biol. Chem. pmid:9624119
Adams SH and Odle J Acetogenesis does not replace ketogenesis in fasting piglets infused with hexanoate. 1998 Am. J. Physiol. pmid:9611143
Allen AK et al. Purification of the glycoprotein lectin from the broad bean (Vicia faba) and a comparison of its properties with lectins of similar specificity. 1976 Biochem. J. pmid:938471
Marshall MO and Knudsen J The specificity of 1-acyl-sn-glycerol 3-phosphate acyltransferase in microsomal fractions from lactating cow mammary gland towards short, medium and long chain acyl-CoA esters. 1977 Biochim. Biophys. Acta pmid:922027
Kasuya F et al. Inhibition of a medium chain acyl-CoA synthetase involved in glycine conjugation by carboxylic acids. 1996 Biochem. Pharmacol. pmid:8937481
Sakiyama Y et al. Evaluation of the brain uptake properties of [1-11C]labeled hexanoate in anesthetized cats by means of positron emission tomography. 1996 Ann Nucl Med pmid:8883717
Ishiwata K et al. A brain uptake study of [1-(11)C]hexanoate in the mouse: the effect of hypoxia, starvation and substrate competition. 1996 Ann Nucl Med pmid:8800460
Bhala A et al. Limitations of 3-phenylpropionylglycine in early screening for medium-chain acyl-coenzyme A dehydrogenase deficiency. 1993 J. Pediatr. pmid:8419594
Conrad JM and Robinson JR Aqueous chamber drug distribution volume measurement in rabbits. 1977 J Pharm Sci pmid:839419
Odle J et al. Emulsification and fatty acid chain length affect the kinetics of [14C]-medium-chain triacylglycerol utilization by neonatal piglets. 1994 J. Nutr. pmid:8283298
Tenma T et al. Development of new lipophilic derivatives of tetragastrin: physicochemical characteristics and intestinal absorption of acyl-tetragastrin derivatives in rats. 1993 Pharm. Res. pmid:8272412
Higa I and Fuyama Y Genetics of food preference in Drosophila sechellia. I. Responses to food attractants. 1993 Genetica pmid:8224853
Yuan J et al. Studies on caproic acid fermentation using immobilized cells. 1993 Chin. J. Biotechnol. pmid:8199321
Youssef J et al. Enoximone inhibits hepatic mitochondrial long-chain acyl-CoA synthetase. 1994 Toxicol. Lett. pmid:8085267
Sundqvist KE et al. Metabolic effects of propionate, hexanoate and propionylcarnitine in normoxia, ischaemia and reperfusion. Does an anaplerotic substrate protect the ischaemic myocardium? 1994 Eur. Heart J. pmid:8070485
Ishiwata K et al. Synthesis and preliminary evaluation of [1-11C]hexanoate as a PET tracer of fatty acid metabolism. 1995 Ann Nucl Med pmid:7779532
Amblard M et al. Synthesis and biological evaluation of cholecystokinin analogs in which the Asp-Phe-NH2 moiety has been replaced by a 3-amino-7-phenylheptanoic acid or a 3-amino-6-(phenyloxy)hexanoic acid. 1993 J. Med. Chem. pmid:7692048
Madden MC et al. Acylcarnitine accumulation does not correlate with reperfusion recovery in palmitate-perfused rat hearts. 1995 Am. J. Physiol. pmid:7611501
Varani J et al. Comparison of cell attachment and caseinolytic activities of five tumour cell types. 1978 J. Cell. Sci. pmid:748334
Hoshi A et al. Antitumor activity of metabolites of 1-hexylcarbamoyl-5-fluorouracil and related compounds against L1210 leukemia in vivo and L5178Y lymphoma cells in vitro. 1980 J. Pharmacobio-dyn. pmid:7463306
Kølvraa S et al. Excretion of short-chain N-acylglycines in the urine of a patient with D-glyceric acidemia. 1980 Clin. Chim. Acta pmid:7408214
Lee IY and McMenamy RH Location of the medium chain fatty acid site on human serum albumin. Residues involved and relationship to the indole site. 1980 J. Biol. Chem. pmid:7391008
Brook I et al. Abnormalities in synovial fluid of patients with septic arthritis detected by gas-liquid chromatography. 1980 Ann. Rheum. Dis. pmid:7387221
Morio M et al. Quantitative analysis of trifluoroacetate in the urine and blood by isotachophoresis. 1980 Anesthesiology pmid:7386909
Kvietys PR et al. Contribution of bile to postprandial intestinal hyperemia. 1980 Am. J. Physiol. pmid:7377305
Lake PE and Ravie O An attempt to improve the fertility of stored fowl semen with certain additives in a basic diluent. 1981 Reprod Nutr Dev pmid:7349569
Soliman SA et al. A direct method to assay neurotoxic esterase activity. 1981 Toxicol. Lett. pmid:7314133
Torgovanova TV et al. [Effect of the quality of regenerated butanol on the process of producing the potassium salt of benzylpenicillin]. 1981 Antibiotiki pmid:7294747
Germain P et al. [delta 1-steroid-dehydrogenase biosynthesis and androsta-4-ene-3,17-dione degradation by "Nocardia restricta" (author's transl)]. 1981 May-Jun Ann. Microbiol. (Paris) pmid:7294608
Cooper AD et al. Mobile haptens in liposomes stimulate serotonin release by rat basophil leukemia cells in the presence of specific immunoglobulin E. 1981 J. Biol. Chem. pmid:7287691
Mortensen PB Urinary excretion of C4--C10-dicarboxylic acids and antiketogenic properties of adipic acid in ketogenic-stimulated rats due to diabetes, long-chain and short-chain monocarboxylic acids. 1981 Biochim. Biophys. Acta pmid:7248329
Bauguess CT et al. Comparison of quantitation methods for L-1210 cell populations and evaluation of selected cytotoxic agents in leukemic mice. 1981 J Pharm Sci pmid:7229929
Talbot A Measurement of adenosine triphosphate and some other metabolites in blood cells by isotachophoresis. I. Preparative technique and enzymatic confirmation. 1982 Acta Med. Okayama pmid:7180574
Berhanu P and Olefsky JM Photoaffinity labeling of insulin receptors in viable cultured human lymphocytes. Demonstration of receptor shedding and degradation. 1982 Diabetes pmid:7152133
Olpin SE and Bates CJ Lipid metabolism in riboflavin-deficient rats. 2. Mitochondrial fatty acid oxidation and the microsomal desaturation pathway. 1982 Br. J. Nutr. pmid:7082627
Hutton JC et al. Similarities in the stimulus-secretion coupling mechanisms of glucose- and 2-keto acid-induced insulin release. 1980 Endocrinology pmid:6985583
Gregersen N et al. Non-ketotic C6-C10-dicarboxylic aciduria: biochemical investigations of two cases. 1980 Clin. Chim. Acta pmid:6892795
Borenstein DG et al. Gas-liquid chromatographic analysis of synovial fluid: volatile short-chain fatty acids in septic arthritis. 1983 Ann. Rheum. Dis. pmid:6882030
Kelly DG and Code CF Absence of Na+--H+ barrier function in mucosa of canine small bowel. 1978 Can. J. Physiol. Pharmacol. pmid:688085
Larsson BK Gas-liquid chromatographic determination of benzoic acid and sorbic acid in foods: NMKL collaborative study. 1983 J Assoc Off Anal Chem pmid:6863197
Dupuis G and Radwan F Synthesis of two photoreactive heterobifunctional reagents derived from hexanoic acid. 1983 Feb-Mar Can. J. Biochem. Cell Biol. pmid:6857759
Berry MN et al. Compartmentation of fatty acid oxidation in liver cells. 1983 Eur. J. Biochem. pmid:6832142
Camargo EE et al. Radiometric measurement of differential metabolism of fatty acid by mycobacteria. 1982 Int. J. Lepr. Other Mycobact. Dis. pmid:6811449
Mangino ME and Weissler NL Interference of lipid with determination of bovine serum albumin by electroimmunodiffusion. 1981 J. Dairy Sci. pmid:6795250
Spydevold O and Hokland B Oxidation of branched-chain amino acids in skeletal muscle and liver of rat. Effects of octanoate and energy state. 1981 Biochim. Biophys. Acta pmid:6793084
Blakley ER The microbial degradation of cyclohexanecarboxylic acid by a beta-oxidation pathway with simultaneous induction to the utilization of benzoate. 1978 Can. J. Microbiol. pmid:679070
Blum JJ Effect of clofibrate on CO2 fixation into glycogen and fatty acids via the leucine catabolism pathway in Tetrahymena. 1980 Biochim. Biophys. Acta pmid:6766749
Kitagawa S et al. Effects of alcohols on ADP-induced aggregation and membrane fluidity of gel-filtered bovine blood platelets. 1984 J. Membr. Biol. pmid:6737467
Spector R and Boose B Accumulation of pantothenic acid by the isolated choroid plexus and brain slices in vitro. 1984 J. Neurochem. pmid:6736962
Dokolina EV et al. [Semisynthetic cerebrosides]. 1983 Bioorg. Khim. pmid:6680305
Naccache PH et al. Modulation of rabbit neutrophil aggregation and degranulation by free fatty acids. 1984 J. Leukoc. Biol. pmid:6592282
Heitkamp MA and Johnson BT Impact of an oil field effluent on microbial activities in a Wyoming river. 1984 Can. J. Microbiol. pmid:6488102
Jakobs C et al. Hydroxy acid metabolites of branched-chain amino acids in amniotic fluid. 1984 Clin. Chim. Acta pmid:6467607
Ghali NI et al. 2-(6-carboxyhexyl)cyclopentanone hexylhydrazone. A potent and time-dependent inhibitor of platelet aggregation. 1983 J. Med. Chem. pmid:6408259
Negishi T and Hayatsu H Inhibitory effect of saturated fatty acids on the mutagenicity of N-nitrosodimethylamine. 1984 Mutat. Res. pmid:6363916
Anderson P and Nagler C Photoaffinity labeling of an interferon-gamma receptor on the surface of cultured fibroblasts. 1984 Biochem. Biophys. Res. Commun. pmid:6329186
Dolmatch B and Niedel J Formyl peptide chemotactic receptor. Evidence for an active proteolytic fragment. 1983 J. Biol. Chem. pmid:6305946
Almquist RG et al. Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion. 1982 J. Med. Chem. pmid:6292422
Foulks JG and Morishita L The temperature dependence of ionic influences on contractile function in frog twitch muscle. 1980 Can. J. Physiol. Pharmacol. pmid:6247041
Kikuchi H and Sato S Fractionation of nonhistone proeins on a column of daunomycin-CH-Sepharose 4B. 1978 Biochim. Biophys. Acta pmid:620048
Gregersen N et al. Biochemical studies in a patient with defects in the metabolism of acyl-CoA and sarcosine: another possible case of glutaric aciduria type II. 1980 J. Inherit. Metab. Dis. pmid:6158623
Day ED and Hashim GA Affinity purification of two populations of antibodies against format determinants of synthetic myelin basic protein peptide S82 from S82-AH- and S82-CH-Sepharose 4B columns. 1984 Neurochem. Res. pmid:6083471
Macpherson JW et al. The effect of caproic acid, handling technique and storage times on the fertility of fowl spermatozoa. 1977 Poult. Sci. pmid:605089
Marshall MO and Knudsen J Biosynthesis of triacylglycerols containing short-chain fatty acids in lactating cow mammary gland. Activity of diacylglycerol acyltransferase towards short-chain acyl-CoA esters. 1977 Eur. J. Biochem. pmid:598368
Chalmers RA and Lawson AM Identification of 5-hydroxyhexanoic acid in the urine of twin siblings with a Reye's-like syndrome associated with dicarboxylic aciduria and hypoglycaemia and with similarities to Jamaican vomiting sickness. 1979 Biomed. Mass Spectrom. pmid:575058
Schoots AC et al. Profiling of uremic serum by high-resolution gas chromatography-electron-impact, chemical ionization mass spectrometry. 1979 J. Chromatogr. pmid:541389
Erickson JS and Paucker K Molecular species of interferon induced in mouse L cells by Newcastle disease virus and polyriboinosinic-polyribocytidylic acid. 1979 J. Gen. Virol. pmid:479847
Carey EM and Dils R The pattern of fatty acid synthesis in lactating rabbit mammary gland studied in vivo. 1972 Biochem. J. pmid:4672462
Kabara JJ et al. Fatty acids and derivatives as antimicrobial agents. 1972 Antimicrob. Agents Chemother. pmid:4670656
Chase JF and Tubbs PK Specific inhibition of mitochondrial fatty acid oxidation by 2-bromopalmitate and its coenzyme A and carnitine esters. 1972 Biochem. J. pmid:4646779
Varani J et al. Cell-associated proteases affect tumour cell migration in vitro. 1979 J. Cell. Sci. pmid:457809
Pokorný J et al. Reactions of oxidized lipids with protein. Part 13. Autoxidation of hexanal in presence of nonlipidic components. 1985 Nahrung pmid:4022111
Levett PN and Phillips KD Gas chromatographic identification of Clostridium difficile and detection of cytotoxin from a modified selective medium. 1985 J. Clin. Pathol. pmid:3968212
Bjorge SM and Baillie TA Inhibition of medium-chain fatty acid beta-oxidation in vitro by valproic acid and its unsaturated metabolite, 2-n-propyl-4-pentenoic acid. 1985 Biochem. Biophys. Res. Commun. pmid:3933498
Haeckel R et al. Hydrazonopropionic acids, a new class of hypoglycemic substances. 5. Inhibition of hepatic gluconeogenesis by 2-(3-methylcinnamyl-hydrazono)-propionate in the rat and guinea pig. 1985 Horm. Metab. Res. pmid:3922863
Mitterer KE [Studies on the hatching of miracidia of Dicrocoelium dendriticum (author's transl)]. 1975 Z Parasitenkd pmid:3901
Zahlsen K et al. Oral intake of a toluene-containing thinner. Effects and headspace gas chromatographic analytical diagnosis. 1985 Arch. Toxicol. Suppl. pmid:3868371
Wright JM et al. The effect of side chain structure on the biochemical and therapeutic properties of intra-articular dexamethasone 21-esters. 1986 Oct-Dec Clin. Exp. Rheumatol. pmid:3791716
Kemp HA and Morgan MR Studies on the detrimental effects of bivalent binding in a microtitration plate ELISA and possible remedies. 1986 J. Immunol. Methods pmid:3782818
Dynnik VV and Djafarov RH Regulation of the tricarboxylic acid cycle and beta-oxidation by excess substrates. 1986 Biochem. Int. pmid:3741443
Berry DJ and Clarke LA Determination of valproic acid (dipropylacetic acid) in plasma by gas-liquid chromatography. 1978 J. Chromatogr. pmid:359583
Handler JA and Thurman RG Rates of H2O2 generation from peroxisomal beta-oxidation are sufficient to account for fatty acid-stimulated ethanol metabolism in perfused rat liver. 1987 Mar-Apr Alcohol pmid:3580135
Stanek R et al. Evaluation of vaginal malodor and efficacy of treatment by high performance ion exchange chromatography. 1987 Biomed. Chromatogr. pmid:3506838
Reckers R [Clinical trial of fluocortin butylester in a double-blind contralateral comparison versus fluocortolone and hydrocortisone acetate (author's transl)]. 1977 Arzneimittelforschung pmid:341901
Honoré B and Brodersen R Detection of carrier heterogeneity by rate of ligand dialysis: medium-chain fatty acid interaction with human serum albumin and competition with chloride. 1988 Anal. Biochem. pmid:3407921
Nakayama H et al. A radioimmunoassay for an advanced glycosylation endproduct. 1988 J. Immunol. Methods pmid:3403989
Madan E and Slifkin M Stool caproic acid for screening of Clostridium difficile. 1988 Am. J. Clin. Pathol. pmid:3354506
van Hoogdalem EJ et al. Absorption enhancement of rectally infused cefoxitin sodium by medium-chain fatty acids in conscious rats: concentration-effect relationship. 1988 Pharm. Res. pmid:3247317
Lala AK et al. Design, synthesis, and fluorescence studies of fluorenyl fatty acids as new depth-dependent fluorescent probes for membranes: getting over the looping-back problem. 1988 Biochemistry pmid:3233217
Rabinowitz JL and Bassett DJ Effect of 2 ppm ozone exposure on rat lung lipid fatty acids. 1988 Exp. Lung Res. pmid:3208714
Epps JM et al. IgA-mediated clearance and tissue deposition of dinitrophenylated human serum albumin at various DNP:HSA ratios. 1988 Mol. Immunol. pmid:3185569
Medvedeva VI et al. [Distribution of oleandomycin between the native broth and butylacetate depending on the biosynthesis conditions]. 1978 Antibiotiki pmid:31834
Salon C et al. Quantification of carbon fluxes through the tricarboxylic acid cycle in early germinating lettuce embryos. 1988 J. Biol. Chem. pmid:3137224
Böhles H et al. The influence of intravenous medium- and long-chain triglycerides and carnitine on the excretion of dicarboxylic acids. 1987 Jan-Feb JPEN J Parenter Enteral Nutr pmid:3102781