Retinoic Acid

Retinoic acid is a lipid of Prenol Lipids (PR) class. Retinoic acid is associated with abnormalities such as Asthma, Dermatologic disorders, Acne, Psoriasis and Vitamin A Deficiency. The involved functions are known as Oxidation, Anabolism, Saturated, 9-cis-retinoic acid biosynthesis and Gene Expression. Retinoic acid often locates in Mouse Testis, Tissue membrane, Body tissue, Membrane and Cytoplasmic matrix. The associated genes with Retinoic Acid are Homologous Gene, SLC33A1 gene, P4HTM gene, RARS gene and NCOR2 gene. The related lipids are Promega, Lipopolysaccharides, Fatty Acids, Steroids and Sterols. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Retinoic Acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Retinoic Acid?

Retinoic Acid is suspected in Retinoic acid syndrome, Dermatologic disorders, Congenital Abnormality, Renal glomerular disease, Acne, Alzheimer's Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Retinoic Acid

MeSH term MeSH ID Detail
Acne Vulgaris D000152 35 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Retinoic Acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Retinoic Acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Retinoic Acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Retinoic Acid?

Related references are published most in these journals:

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What genes are associated with Retinoic Acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Retinoic Acid?

Mouse Model

Mouse Model are used in the study 'Targeted disruption of the mouse cis-retinol dehydrogenase gene: visual and nonvisual functions.' (Shang E et al., 2002) and Mouse Model are used in the study '9-Cis retinoic acid reduces 1alpha,25-dihydroxycholecalciferol-induced renal calcification by altering vitamin K-dependent gamma-carboxylation of matrix gamma-carboxyglutamic acid protein in A/J male mice.' (Fu X et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Retinoic Acid

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Authors Title Published Journal PubMed Link
Kikuchi H et al. Resveratrol strongly enhances the retinoic acid-induced superoxide generating activity via up-regulation of gp91-phox gene expression in U937 cells. 2018 Biochem. Biophys. Res. Commun. pmid:29183727
Kartal D et al. Effects of isotretinoin on the olfactory function in patients with acne. 2017 Mar-Apr An Bras Dermatol pmid:28538877
Okitsu T et al. Alternative Formation of Red-Shifted Channelrhodopsins: Noncovalent Incorporation with Retinal-Based Enamine-Type Schiff Bases and Mutated Channelopsin. 2017 Chem. Pharm. Bull. pmid:28381675
Zou H et al. Upregulation of CD54 and downregulation of HLA‑ABC contribute to the novel enhancement of the susceptibility of HL-60 cells to NK cell-mediated cytolysis induced by ATRA plus VPA. 2017 Oncol. Rep. pmid:27840957
Yao S et al. Epigallocatechin-3-gallate promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells via PTEN. 2017 Int. J. Oncol. pmid:28766684
Nakazawa T et al. Effect of vitamin E on 24(S)-hydroxycholesterol-induced necroptosis-like cell death and apoptosis. 2017 J. Steroid Biochem. Mol. Biol. pmid:26953980
Li C et al. Effects of Pre- and Post-Administration of Vitamin A on the Growth of Refractory Cancers in Xenograft Mice. 2017 Biol. Pharm. Bull. pmid:28100867
Roomi MW et al. Cytokines, inducers and inhibitors modulate MMP-2 and MMP‑9 secretion by human Fanconi anemia immortalized fibroblasts. 2017 Oncol. Rep. pmid:28098879
Kumar P et al. Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in haplotype male mice. 2017 Am. J. Physiol. Renal Physiol. pmid:28566502
Mijiddorj T et al. Retinoic acid and retinaldehyde dehydrogenase are not involved in the specific induction of the follicle-stimulating hormone β subunit by trichostatin A, a selective inhibitor of histone deacetylase. 2017 Gen. Comp. Endocrinol. pmid:26654743