| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acne Vulgaris | D000152 | 35 associated lipids |
Total
1
Retinoic Acid
Retinoic acid is a lipid of Prenol Lipids (PR) class. Retinoic acid is associated with abnormalities such as Asthma, Dermatologic disorders, Acne, Psoriasis and Vitamin A Deficiency. The involved functions are known as Oxidation, Anabolism, Saturated, 9-cis-retinoic acid biosynthesis and Gene Expression. Retinoic acid often locates in Mouse Testis, Tissue membrane, Body tissue, Membrane and Cytoplasmic matrix. The associated genes with Retinoic Acid are Homologous Gene, SLC33A1 gene, P4HTM gene, RARS gene and NCOR2 gene. The related lipids are Promega, Lipopolysaccharides, Fatty Acids, Steroids and Sterols. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Retinoic Acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Retinoic Acid?
Retinoic Acid is suspected in Retinoic acid syndrome, Dermatologic disorders, Congenital Abnormality, Renal glomerular disease, Acne, Alzheimer's Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Retinoic Acid
PubChem Associated disorders and diseases
What pathways are associated with Retinoic Acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Retinoic Acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Retinoic Acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Retinoic Acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Retinoic Acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Retinoic Acid?
Mouse Model
Mouse Model are used in the study 'Targeted disruption of the mouse cis-retinol dehydrogenase gene: visual and nonvisual functions.' (Shang E et al., 2002) and Mouse Model are used in the study '9-Cis retinoic acid reduces 1alpha,25-dihydroxycholecalciferol-induced renal calcification by altering vitamin K-dependent gamma-carboxylation of matrix gamma-carboxyglutamic acid protein in A/J male mice.' (Fu X et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Retinoic Acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kikuchi H et al. | Resveratrol strongly enhances the retinoic acid-induced superoxide generating activity via up-regulation of gp91-phox gene expression in U937Â cells. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29183727 |
| Kartal D et al. | Effects of isotretinoin on the olfactory function in patients with acne. | 2017 Mar-Apr | An Bras Dermatol | pmid:28538877 |
| Pascua-Maestro R et al. | Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress. | 2017 | PLoS Genet. | pmid:28182653 |
| Berlin Grace VM et al. | Enhanced expression of tumour suppressor RAR-β by DSPC nano-formulated lipo-ATRA in the lung of B16F10 cell-implanted C57BL6 mice and in A549 cells. | 2017 | Life Sci. | pmid:28694088 |
| Gong X et al. | Inhibition of pulmonary β-carotene 15, 15'-oxygenase expression by glucocorticoid involves PPARα. | 2017 | PLoS ONE | pmid:28732066 |
| Okitsu T et al. | Alternative Formation of Red-Shifted Channelrhodopsins: Noncovalent Incorporation with Retinal-Based Enamine-Type Schiff Bases and Mutated Channelopsin. | 2017 | Chem. Pharm. Bull. | pmid:28381675 |
| Zou H et al. | Upregulation of CD54 and downregulation of HLA‑ABC contribute to the novel enhancement of the susceptibility of HL-60 cells to NK cell-mediated cytolysis induced by ATRA plus VPA. | 2017 | Oncol. Rep. | pmid:27840957 |
| Yao S et al. | Epigallocatechin-3-gallate promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells via PTEN. | 2017 | Int. J. Oncol. | pmid:28766684 |
| Rybakovsky E et al. | Improvement of Human-Oral-Epithelial-Barrier Function and of Tight Junctions by Micronutrients. | 2017 | J. Agric. Food Chem. | pmid:29172516 |
| Nakazawa T et al. | Effect of vitamin E on 24(S)-hydroxycholesterol-induced necroptosis-like cell death and apoptosis. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:26953980 |
| Li C et al. | Effects of Pre- and Post-Administration of Vitamin A on the Growth of Refractory Cancers in Xenograft Mice. | 2017 | Biol. Pharm. Bull. | pmid:28100867 |
| Roomi MW et al. | Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells. | 2017 | Oncol. Rep. | pmid:28112361 |
| Roomi MW et al. | Cytokines, inducers and inhibitors modulate MMP-2 and MMP‑9 secretion by human Fanconi anemia immortalized fibroblasts. | 2017 | Oncol. Rep. | pmid:28098879 |
| Setiawan M et al. | Inhibiting glycogen synthase kinase-3 and transforming growth factor-β signaling to promote epithelial transition of human adipose mesenchymal stem cells. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28698144 |
| Kumar P et al. | Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in haplotype male mice. | 2017 | Am. J. Physiol. Renal Physiol. | pmid:28566502 |
| Mijiddorj T et al. | Retinoic acid and retinaldehyde dehydrogenase are not involved in the specific induction of the follicle-stimulating hormone β subunit by trichostatin A, a selective inhibitor of histone deacetylase. | 2017 | Gen. Comp. Endocrinol. | pmid:26654743 |
| Park S et al. | Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents. | 2017 | J. Clin. Oncol. | pmid:28350519 |
| Abed M et al. | Stimulation of Phospholipid Scrambling of the Erythrocyte Membrane by 9-Cis-Retinoic Acid. | 2017 | Cell. Physiol. Biochem. | pmid:28214868 |
| Fan W et al. | An unusual case of folliculitis spinulosa decalvans. | 2016 | Cutis | pmid:27814407 |
| Kedishvili NY | Retinoic Acid Synthesis and Degradation. | 2016 | Subcell. Biochem. | pmid:27830503 |
| Napoli JL | Functions of Intracellular Retinoid Binding-Proteins. | 2016 | Subcell. Biochem. | pmid:27830500 |
| Hong SH et al. | Alternative Biotransformation of Retinal to Retinoic Acid or Retinol by an Aldehyde Dehydrogenase from Bacillus cereus. | 2016 | Appl. Environ. Microbiol. | pmid:27107124 |
| Bhanu NV et al. | Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation. | 2016 | Proteomics | pmid:26631989 |
| Mastorci K et al. | Phospholipid scramblase 1 as a critical node at the crossroad between autophagy and apoptosis in mantle cell lymphoma. | 2016 | Oncotarget | pmid:27248824 |
| Papi A et al. | Epigallocatechin-3-gallate Increases RXRγ-mediated Pro-apoptotic and Anti-invasive Effects in Gastrointestinal Cancer Cell Lines. | 2016 | Curr Cancer Drug Targets | pmid:26278714 |
| Li AS and Marikawa Y | Adverse effect of valproic acid on an in vitro gastrulation model entails activation of retinoic acid signaling. | 2016 | Reprod. Toxicol. | pmid:27693483 |
| Hamed EA et al. | Role of monocyte chemoattractant protein-1, stromal derived factor-1 and retinoic acid in pathophysiology of neuropathic pain in rats. | 2016 | J Basic Clin Physiol Pharmacol | pmid:26974138 |
| Regen F et al. | Inhibition of brain retinoic acid catabolism: a mechanism for minocycline's pleiotropic actions? | 2016 | World J. Biol. Psychiatry | pmid:26047390 |
| Morrissy SJ et al. | Differential Regulation of Bcl-xL Gene Expression by Corticosterone, Progesterone, and Retinoic Acid. | 2016 | J. Biochem. Mol. Toxicol. | pmid:26915917 |
| Yang L et al. | All-trans retinoic acid protects against doxorubicin-induced cardiotoxicity by activating the ERK2 signalling pathway. | 2016 | Br. J. Pharmacol. | pmid:26507774 |
| Li C et al. | Inhibitory Effects of Retinol Are Greater than Retinoic Acid on the Growth and Adhesion of Human Refractory Cancer Cells. | 2016 | Biol. Pharm. Bull. | pmid:26822412 |
| Gall BJ et al. | Reduction of GPSM3 expression akin to the arthritis-protective SNP rs204989 differentially affects migration in a neutrophil model. | 2016 | Genes Immun. | pmid:27307211 |
| Lemaire B et al. | Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders. | 2016 | Toxicol. Appl. Pharmacol. | pmid:26853319 |
| Sakai H et al. | Chemoprevention of obesity-related liver carcinogenesis by using pharmaceutical and nutraceutical agents. | 2016 | World J. Gastroenterol. | pmid:26755885 |
| Ho VW et al. | All Trans Retinoic Acid, Transforming Growth Factor β and Prostaglandin E2 in Mouse Plasma Synergize with Basophil-Secreted Interleukin-4 to M2 Polarize Murine Macrophages. | 2016 | PLoS ONE | pmid:27977740 |
| Liu F et al. | Exploring an animal model of amodiaquine-induced liver injury in rats and mice. | 2016 | J Immunotoxicol | pmid:27416278 |
| Bailey JM et al. | Persistent behavioral effects following early life exposure to retinoic acid or valproic acid in zebrafish. | 2016 | Neurotoxicology | pmid:26439099 |
| Patties I et al. | Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugs. | 2016 | J. Exp. Clin. Cancer Res. | pmid:27317342 |
| Xing F et al. | Effect of retinoic acid on aquaporin 3 expression in keratinocytes. | 2016 | Genet. Mol. Res. | pmid:26985947 |
| Subramanian U et al. | Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice. | 2016 | Physiol. Genomics | pmid:27199456 |
| Holm KL et al. | Myeloid cell leukaemia 1 has a vital role in retinoic acid-mediated protection of Toll-like receptor 9-stimulated B cells from spontaneous and DNA damage-induced apoptosis. | 2016 | Immunology | pmid:27278254 |
| Clarke CJ et al. | ATRA transcriptionally induces nSMase2 through CBP/p300-mediated histone acetylation. | 2016 | J. Lipid Res. | pmid:27013100 |
| Chen X et al. | Differentiation-inducing and anti-proliferative activities of isoliquiritigenin and all-trans-retinoic acid on B16F0 melanoma cells: Mechanisms profiling by RNA-seq. | 2016 | Gene | pmid:27461947 |
| Hiromori Y et al. | Ligand Activity of Group 15 Compounds Possessing Triphenyl Substituent for the RXR and PPARγ Nuclear Receptors. | 2016 | Biol. Pharm. Bull. | pmid:27725436 |
| Hong WS et al. | Development of a Highly Sensitive Cell-Based Assay for Detecting Botulinum Neurotoxin Type A through Neural Culture Media Optimization. | 2016 | J Biomol Screen | pmid:26420788 |
| Ghate VM et al. | Nanostructured lipid carriers for the topical delivery of tretinoin. | 2016 | Eur J Pharm Biopharm | pmid:27519827 |
| Paoletti L et al. | Lysophosphatidylcholine Drives Neuroblast Cell Fate. | 2016 | Mol. Neurobiol. | pmid:26567110 |
| Wang Y et al. | [Homoharringtonine in newly diagnosed acute promyelocytic leukemia treatment: a prospective, randomized controlled trial]. | 2016 | Zhonghua Xue Ye Xue Za Zhi | pmid:27033753 |
| Matsui M et al. | Protective and therapeutic effects of fucoxanthin against sunburn caused by UV irradiation. | 2016 | J. Pharmacol. Sci. | pmid:27590588 |
| Lin YK et al. | Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs. | 2015 | PLoS ONE | pmid:26355594 |