13-cis-retinoic acid,Isotretinoin

13-cis-retinoic acid,isotretinoin is a lipid of Prenol Lipids (PR) class. 13-cis-retinoic acid,isotretinoin is associated with abnormalities such as Dermatitis, Phototoxic. The involved functions are known as Regulation, Pigment, chromophore, Light absorption and Pupil constriction. 13-cis-retinoic acid,isotretinoin often locates in Neurosecretory Systems. The associated genes with 13-cis-retinoic acid,Isotretinoin are melanopsin.

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Introduction

To understand associated biological information of 13-cis-retinoic acid,Isotretinoin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 13-cis-retinoic acid,Isotretinoin?

13-cis-retinoic acid,Isotretinoin is suspected in Dermatitis, Phototoxic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 13-cis-retinoic acid,Isotretinoin

MeSH term MeSH ID Detail
Lymphoma, Large-Cell, Anaplastic D017728 3 associated lipids
Acne Vulgaris D000152 35 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Lung Neoplasms D008175 171 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with 13-cis-retinoic acid,Isotretinoin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 13-cis-retinoic acid,Isotretinoin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 13-cis-retinoic acid,Isotretinoin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 13-cis-retinoic acid,Isotretinoin?

There are no associated biomedical information in the current reference collection.

What genes are associated with 13-cis-retinoic acid,Isotretinoin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 13-cis-retinoic acid,Isotretinoin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 13-cis-retinoic acid,Isotretinoin

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Authors Title Published Journal PubMed Link
Kameoka S et al. A high-throughput screen for teratogens using human pluripotent stem cells. 2014 Toxicol. Sci. pmid:24154490
Macejová D et al. Different mRNA expression profiling of nuclear retinoid, thyroid, estrogen and PPARgamma receptors, their coregulators and selected genes in rat liver and spleen in response to short-term in vivo administration of 13-cis retinoic acid. 2009 Toxicol. Lett. pmid:19041696
Ratajewski M et al. Screening of a chemical library reveals novel PXR-activating pharmacologic compounds. 2015 Toxicol. Lett. pmid:25455453
Willhite CC et al. Distribution, teratogenicity, and embryonic delivered dose of retinoid Ro 23-9223. 2000 Toxicol. Appl. Pharmacol. pmid:10764630
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Eckhoff C et al. Teratogenicity and transplacental pharmacokinetics of 13-cis-retinoic acid in rabbits. 1994 Toxicol. Appl. Pharmacol. pmid:8128493
Silva FS et al. The in vitro and in vivo genotoxicity of isotretinoin assessed by cytokinesis blocked micronucleus assay and comet assay. 2013 Toxicol In Vitro pmid:23318729
Rødland O and Helland S [Hypertrophic granulation tissue as a complication to isotretinoin treatment]. 1991 Tidsskr. Nor. Laegeforen. pmid:1835182