MeSH term | MeSH ID | Detail |
---|---|---|
Lymphoma, Large-Cell, Anaplastic | D017728 | 3 associated lipids |
Acne Vulgaris | D000152 | 35 associated lipids |
Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
13-cis-retinoic acid,isotretinoin is a lipid of Prenol Lipids (PR) class. 13-cis-retinoic acid,isotretinoin is associated with abnormalities such as Dermatitis, Phototoxic. The involved functions are known as Regulation, Pigment, chromophore, Light absorption and Pupil constriction. 13-cis-retinoic acid,isotretinoin often locates in Neurosecretory Systems. The associated genes with 13-cis-retinoic acid,Isotretinoin are melanopsin.
To understand associated biological information of 13-cis-retinoic acid,Isotretinoin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
13-cis-retinoic acid,Isotretinoin is suspected in Dermatitis, Phototoxic and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 13-cis-retinoic acid,Isotretinoin
MeSH term | MeSH ID | Detail |
---|---|---|
Lymphoma, Large-Cell, Anaplastic | D017728 | 3 associated lipids |
Acne Vulgaris | D000152 | 35 associated lipids |
Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Macejová D et al. | Different mRNA expression profiling of nuclear retinoid, thyroid, estrogen and PPARgamma receptors, their coregulators and selected genes in rat liver and spleen in response to short-term in vivo administration of 13-cis retinoic acid. | 2009 | Toxicol. Lett. | pmid:19041696 |
Ratajewski M et al. | Screening of a chemical library reveals novel PXR-activating pharmacologic compounds. | 2015 | Toxicol. Lett. | pmid:25455453 |
Willhite CC et al. | Distribution, teratogenicity, and embryonic delivered dose of retinoid Ro 23-9223. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10764630 |
Collins MD et al. | Comparative teratology and transplacental pharmacokinetics of all-trans-retinoic acid, 13-cis-retinoic acid, and retinyl palmitate following daily administrations in rats. | 1994 | Toxicol. Appl. Pharmacol. | pmid:8048045 |
Tzimas G et al. | Developmental stage-associated differences in the transplacental distribution of 13-cis- and all-trans-retinoic acid as well as their glucuronides in rats and mice. | 1995 | Toxicol. Appl. Pharmacol. | pmid:7597714 |
Eckhoff C and Willhite CC | Embryonic delivered dose of isotretinoin (13-cis-retinoic acid) and its metabolites in hamsters. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9299599 |
Eckhoff C et al. | Teratogenicity and transplacental pharmacokinetics of 13-cis-retinoic acid in rabbits. | 1994 | Toxicol. Appl. Pharmacol. | pmid:8128493 |
Silva FS et al. | The in vitro and in vivo genotoxicity of isotretinoin assessed by cytokinesis blocked micronucleus assay and comet assay. | 2013 | Toxicol In Vitro | pmid:23318729 |
Rødland O and Helland S | [Hypertrophic granulation tissue as a complication to isotretinoin treatment]. | 1991 | Tidsskr. Nor. Laegeforen. | pmid:1835182 |