13-cis-retinoic acid,Isotretinoin

13-cis-retinoic acid,isotretinoin is a lipid of Prenol Lipids (PR) class. 13-cis-retinoic acid,isotretinoin is associated with abnormalities such as Dermatitis, Phototoxic. The involved functions are known as Regulation, Pigment, chromophore, Light absorption and Pupil constriction. 13-cis-retinoic acid,isotretinoin often locates in Neurosecretory Systems. The associated genes with 13-cis-retinoic acid,Isotretinoin are melanopsin.

Cross Reference

Introduction

To understand associated biological information of 13-cis-retinoic acid,Isotretinoin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 13-cis-retinoic acid,Isotretinoin?

13-cis-retinoic acid,Isotretinoin is suspected in Dermatitis, Phototoxic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 13-cis-retinoic acid,Isotretinoin

MeSH term MeSH ID Detail
Acne Vulgaris D000152 35 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lymphoma, Large-Cell, Anaplastic D017728 3 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with 13-cis-retinoic acid,Isotretinoin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 13-cis-retinoic acid,Isotretinoin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 13-cis-retinoic acid,Isotretinoin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 13-cis-retinoic acid,Isotretinoin?

There are no associated biomedical information in the current reference collection.

What genes are associated with 13-cis-retinoic acid,Isotretinoin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 13-cis-retinoic acid,Isotretinoin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 13-cis-retinoic acid,Isotretinoin

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Authors Title Published Journal PubMed Link
Lynberg MC et al. Sensitivity, specificity, and positive predictive value of multiple malformations in isotretinoin embryopathy surveillance. 1990 Teratology pmid:2278026
Recommendations for isotretinoin use in women of childbearing potential. 1991 Teratology pmid:1957255
Robertson JA et al. Accutane cases: a teratogen information service's approach. 2002 Teratology pmid:12115772
Irving DW et al. Morphogenesis of isotretinoin-induced microcephaly and micrognathia studied by scanning electron microscopy. 1986 Teratology pmid:3465061
Kubow S Inhibition of isotretinoin teratogenicity by acetylsalicylic acid pretreatment in mice. 1992 Teratology pmid:1731396
Rizzo R et al. Limb reduction defects in humans associated with prenatal isotretinoin exposure. 1991 Teratology pmid:1805430
Kwasigroch TE and Bullen M Effects of isotretinoin (13-cis-retinoic acid) on the development of mouse limbs in vivo and in vitro. 1991 Teratology pmid:1805431
Makori N et al. 13-cis-retinoic acid causes patterning defects in the early embryonic rostral hindbrain and abnormal development of the cerebellum in the macaque. 2001 Teratology pmid:11241428
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Rouzès A and Jonville-Béra AP [Exposure to isotretinoin during pregnancy in France: 25 years of follow-up]. 2014 Jan-Feb Therapie pmid:24698189
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Taillan B et al. [Paroxysmal nocturnal hemoglobinuria and hemolysis induced by isotretinoin]. 1994 Sep-Oct Therapie pmid:7855773
Wallnöfer AE et al. Effect of isotretinoin on endogenous tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) in humans. 1993 Thromb. Haemost. pmid:8165591
Pernod G et al. Retinoids induced t-PA synthesis by C6 glioma cells--role in tumoral haemorrhagic necrosis. 1996 Thromb. Haemost. pmid:8815586
Berg G et al. Development of severe thyroid-associated ophthalmopathy in a patient with disseminated thyroid cancer treated with recombinant human thyrotropin/radioiodine and retinoic acid. 2005 Thyroid pmid:16405414
Coelho SM et al. Isotretinoin as a diagnostic tool for localization of thyroid tissue in a thyroid cancer patient: a case report. 2007 Thyroid pmid:17956163