13-cis-retinoic acid,Isotretinoin

13-cis-retinoic acid,isotretinoin is a lipid of Prenol Lipids (PR) class. 13-cis-retinoic acid,isotretinoin is associated with abnormalities such as Dermatitis, Phototoxic. The involved functions are known as Regulation, Pigment, chromophore, Light absorption and Pupil constriction. 13-cis-retinoic acid,isotretinoin often locates in Neurosecretory Systems. The associated genes with 13-cis-retinoic acid,Isotretinoin are melanopsin.

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Introduction

To understand associated biological information of 13-cis-retinoic acid,Isotretinoin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 13-cis-retinoic acid,Isotretinoin?

13-cis-retinoic acid,Isotretinoin is suspected in Dermatitis, Phototoxic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 13-cis-retinoic acid,Isotretinoin

MeSH term MeSH ID Detail
Lung Neoplasms D008175 171 associated lipids
Acne Vulgaris D000152 35 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Lymphoma, Large-Cell, Anaplastic D017728 3 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with 13-cis-retinoic acid,Isotretinoin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 13-cis-retinoic acid,Isotretinoin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 13-cis-retinoic acid,Isotretinoin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 13-cis-retinoic acid,Isotretinoin?

There are no associated biomedical information in the current reference collection.

What genes are associated with 13-cis-retinoic acid,Isotretinoin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 13-cis-retinoic acid,Isotretinoin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 13-cis-retinoic acid,Isotretinoin

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Authors Title Published Journal PubMed Link
Jones DH et al. Hidradenitis suppurativa-lack of success with 13-cis-retinoic acid. 1982 Br. J. Dermatol. pmid:6954970
Jones DH et al. Treatment of Gram-negative folliculitis with 13-cis-retinoic acid. 1982 Br. J. Dermatol. pmid:6954971
Macek C Synthetic vitamin A analogue (isotretinoin) awaiting approval for cystic acne therapy. 1982 JAMA pmid:6460881
Zile MH et al. Metabolites of all-trans-retinoic acid in bile: identification of all-trans- and 13-cis-retinoyl glucuronides. 1982 J. Biol. Chem. pmid:6949903
Zile MH et al. Metabolism in vivo of all-trans-retinoic acid. Biosynthesis of 13-cis-retinoic acid and all-trans- and 13-cis-retinoyl glucuronides in the intestinal mucosa of the rat. 1982 J. Biol. Chem. pmid:6949904
McGuire J et al. The influence of retinoids on cultivated human keratinocytes. 1982 J. Am. Acad. Dermatol. pmid:6175669
Kerr IG et al. Pharmacology of 13-cis-retinoic acid in humans. 1982 Cancer Res. pmid:7039821
Peck GL Retinoids. Therapeutic use in dermatology. 1982 Drugs pmid:6183090
Goldstein JA et al. Isotretinoin in the treatment of acne: histologic changes, sebum production, and clinical observations. 1982 Arch Dermatol pmid:6213204
Milson J et al. Ophthalmological effects of 13-cis-retinoic acid therapy for acne vulgaris. 1982 Br. J. Dermatol. pmid:6215054
Windhorst DB The use of isotretinoin in disorders of keratinization. 1982 J. Am. Acad. Dermatol. pmid:6175670
Khoo KC et al. Pharmacokinetics of isotretinoin following a single oral dose. 1982 Aug-Sep J Clin Pharmacol pmid:6957421
Patel IH et al. Pharmacokinetics of tretinoin and its in vivo isomeric conversion to isotretinoin in the dog. 1982 Jul-Aug Drug Metab. Dispos. pmid:6126339
Kalin JR et al. Disposition of 13-cis-retinoic acid and N-(2-hydroxyethyl)retinamide in mice after oral doses. 1982 Jul-Aug Drug Metab. Dispos. pmid:6126340
Vane FM et al. Metabolism of 13-cis-retinoic acid by a rat liver 9000g supernatant preparation. 1982 May-Jun Drug Metab. Dispos. pmid:6125352
Patel LH et al. Comparative pharmacokinetics of isotretinoin and its metabolite, 4-Oxo-isotretinoin, in dogs. 1982 May-Jun Drug Metab. Dispos. pmid:6125366
Zech LA et al. Changes in plasma cholesterol and triglyceride levels after treatment with oral isotretinoin. A prospective study. 1983 Arch Dermatol pmid:6228196
Hicks RM The scientific basis for regarding vitamin A and its analogues as anti-carcinogenic agents. 1983 Proc Nutr Soc pmid:6220411
Hönigsmann H and Wolff K Isotretinoin-PUVA for psoriasis. 1983 Lancet pmid:6130263
Cowan JD et al. Use of a human tumor cloning system to screen retinoids for antineoplastic activity. 1983 Cancer pmid:6571795
Chertow BS et al. Cellular mechanisms of insulin release. Effects of retinoids on rat islet cell-to-cell adhesion, reaggregation, and insulin release. 1983 Diabetes pmid:6354784
Alam SQ and Alam BS Lipid peroxide, alpha-tocopherol and retinoid levels in plasma and liver of rats fed diets containing beta-carotene and 13-cis-retinoic acid. 1983 J. Nutr. pmid:6581276
Marsden JR et al. Isotretinoin and serum lipids. 1983 Lancet pmid:6129453
Roach M A malignant eccrine poroma responds to isotretinoin (13-cis-retinoic acid). 1983 Ann. Intern. Med. pmid:6312862
Pittsley RA and Yoder FW Retinoid hyperostosis. Skeletal toxicity associated with long-term administration of 13-cis-retinoic acid for refractory ichthyosis. 1983 N. Engl. J. Med. pmid:6403861
Kingston T et al. Isotretinoin and serum lipids. 1983 Lancet pmid:6131187
Kessler JF et al. Treatment of cutaneous T-cell lymphoma (mycosis fungoides) with 13-cis-retinoic acid. 1983 Lancet pmid:6134133
Alexander M Treatment of mycosis fungoides with isotretinoin. 1983 Lancet pmid:6135953
Rosa FW Teratogenicity of isotretinoin. 1983 Lancet pmid:6136666
Warrell RP et al. Isotretinoin in cutaneous T-cell lymphoma. 1983 Lancet pmid:6136780
Alam BS and Alam SQ Excessive intake of 13-cis retinoic acid and fatty acid composition of tissues. 1983 J. Nutr. pmid:6571878
Sadek IA Opalina ranarum: inhibitory effect of 13-cis-retinoic acid or retinyl palmitate on the induction of cyst formation. 1983 Exp. Parasitol. pmid:6413239
Shah JP et al. Effect of retinoids on oral leukoplakia. 1983 Am. J. Surg. pmid:6578687
Yoder FW Isotretinoin: a word of caution. 1983 JAMA pmid:6217354
Waldinger TP et al. Treatment of cutaneous sarcoidosis with isotretinoin. 1983 Arch Dermatol pmid:6580843
Simpson NB and Martin AR A more reliable photometric technique for the measurement of scalp sebum excretion. 1983 Br. J. Dermatol. pmid:6580909
Jones DH et al. A dose-response study of I3-cis-retinoic acid in acne vulgaris. 1983 Br. J. Dermatol. pmid:6219690
Pochi PE Hormones, retinoids, and acne. 1983 N. Engl. J. Med. pmid:6220223
Andrus TR and Smith JG Retinoids in clinical medicine. 1983 South. Med. J. pmid:6221408
Ensink BW and van Voorst Vader PC Ophthalmological side-effects of 13-cis-retinoid therapy. 1983 Br. J. Dermatol. pmid:6221749
Schachner L The treatment of acne: a contemporary review. 1983 Pediatr. Clin. North Am. pmid:6224127
Kanigsberg N and DesGroseilliers JP Use of 13-cis-retinoic acid in cystic acne. 1983 Can Med Assoc J pmid:6222787
New therapy for severe cystic acne. 1983 Pediatrics pmid:6223269
Meyskens FL et al. Effect of 13-cis-retinoic acid and 4-hydroxyphenyl-all-trans-retinamide on human tumor colony formation in soft agar. 1983 Int. J. Cancer pmid:6224747
Exner JH et al. Pyogenic granuloma-like acne lesions during isotretinoin therapy. 1983 Arch Dermatol pmid:6225396
Bollag W Vitamin A and retinoids: from nutrition to pharmacotherapy in dermatology and oncology. 1983 Lancet pmid:6132186
Valentic JP et al. Inflammatory neovascular nodules associated with oral isotretinoin treatment of severe acne. 1983 Arch Dermatol pmid:6225399
Henderson IW and Rice WB Accutane. 1983 Can Med Assoc J pmid:6225503
Valentic JP et al. Hypercalcemia associated with oral isotretinoin in the treatment of severe acne. 1983 JAMA pmid:6225882
Mahrle G Retinoids in skin cancer and hyperproliferative skin disease. 1983 J Dermatol Surg Oncol pmid:6409950