Coenzyme Q10

Coenzyme q10 is a lipid of Prenol Lipids (PR) class. Coenzyme q10 is associated with abnormalities such as Nephrotic Syndrome, Diabetes, COENZYME Q10 DEFICIENCY, Deafness and Hypertensive disease. The involved functions are known as Mutation, Process, Oxidation, Electron Transport and Oxidants. Coenzyme q10 often locates in Mitochondria, soluble, Plasma membrane, Body tissue and Inner mitochondrial membrane. The associated genes with Coenzyme Q10 are MT-CYB gene, ATP5B gene, cytochrome c'', STN gene and NPC1 gene. The related lipids are Total cholesterol and Lipid Peroxides. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Coenzyme Q10, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coenzyme Q10?

Coenzyme Q10 is suspected in Heart failure, Myocardial Ischemia, COENZYME Q10 DEFICIENCY, Neurodegenerative Disorders, Myocardial Infarction, Glaucoma and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coenzyme Q10

MeSH term MeSH ID Detail
Rare Diseases D035583 2 associated lipids
Neglected Diseases D058069 3 associated lipids
MELAS Syndrome D017241 3 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Body Weight D001835 333 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with Coenzyme Q10

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coenzyme Q10?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Coenzyme Q10?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coenzyme Q10?

Related references are published most in these journals:

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What genes are associated with Coenzyme Q10?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coenzyme Q10?

Mouse Model

Mouse Model are used in the study 'Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage.' (Lulli M et al., 2012).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Coenzyme Q10

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Authors Title Published Journal PubMed Link
García Verazaluce JJ et al. [Effect of phlebodium decumanum and coenzyme Q10 on sports performance in professional volleyball players]. 2014 Nutr Hosp pmid:25561135
Zhang K et al. A germline missense mutation in COQ6 is associated with susceptibility to familial schwannomatosis. 2014 Genet. Med. pmid:24763291
Kömürcü E et al. Preventive effects of coenzyme Q10 (CoQ10) on steroid-induced osteonecrosis in rats. 2014 Acta Orthop Traumatol Turc pmid:24747633
Giannubilo SR et al. Amniotic coenzyme Q10: is it related to pregnancy outcomes? 2014 Antioxid. Redox Signal. pmid:24745321
Gironi M et al. Oxidative stress is differentially present in multiple sclerosis courses, early evident, and unrelated to treatment. 2014 J Immunol Res pmid:24741637
Holloway CJ et al. Oral Coenzyme Q10 supplementation does not prevent cardiac alterations during a high altitude trek to everest base cAMP. 2014 High Alt. Med. Biol. pmid:24661196
Amin MM et al. Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, Tyrosine kinase, PI3K, glucose transporters, sRAGE and visfatin in insulin resistant/diabetic rats. 2014 PLoS ONE pmid:24586567
Chandra A et al. Prospects for neuroprotective therapies in prodromal Huntington's disease. 2014 Mov. Disord. pmid:24573776
Roseiro LC et al. Concentration of antioxidants in two muscles of mature dairy cows from Azores. 2014 Meat Sci. pmid:24211545
Khorrami A et al. Reduction of coenzyme q10 content: a possible effect of isoproterenol on heart failure and myocardial infarction in rat. 2014 Drug Res (Stuttg) pmid:24026955
Doimo M et al. Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency. 2014 Biochim. Biophys. Acta pmid:24140869
Wang D et al. Coenzyme Q10 promotes macrophage cholesterol efflux by regulation of the activator protein-1/miR-378/ATP-binding cassette transporter G1-signaling pathway. 2014 Arterioscler. Thromb. Vasc. Biol. pmid:24675662
Lu W et al. Enhanced production of coenzyme Q10 by self-regulating the engineered MEP pathway in Rhodobacter sphaeroides. 2014 Biotechnol. Bioeng. pmid:24122603
Xu C et al. Light-harvesting chlorophyll pigments enable mammalian mitochondria to capture photonic energy and produce ATP. 2014 J. Cell. Sci. pmid:24198392
Onoue S et al. Biopharmaceutical characterization of nanocrystalline solid dispersion of coenzyme Q10 prepared with cold wet-milling system. 2014 Eur J Pharm Sci pmid:24368114
Contin M et al. The use of coenzyme Q0 as a template in the development of a molecularly imprinted polymer for the selective recognition of coenzyme Q10. 2014 Anal. Chim. Acta pmid:24356222
Garrido-Maraver J et al. Clinical applications of coenzyme Q10. 2014 Front Biosci (Landmark Ed) pmid:24389208
López-Nicolás JM et al. Cyclodextrins and antioxidants. 2014 Crit Rev Food Sci Nutr pmid:24188271
Dadabayev AR et al. Apolipoprotein A1 regulates coenzyme Q10 absorption, mitochondrial function, and infarct size in a mouse model of myocardial infarction. 2014 J. Nutr. pmid:24759932
Tompkins R et al. A current approach to statin intolerance. 2014 Clin. Pharmacol. Ther. pmid:24727470