Coenzyme Q10

Coenzyme q10 is a lipid of Prenol Lipids (PR) class. Coenzyme q10 is associated with abnormalities such as Nephrotic Syndrome, Diabetes, COENZYME Q10 DEFICIENCY, Deafness and Hypertensive disease. The involved functions are known as Mutation, Process, Oxidation, Electron Transport and Oxidants. Coenzyme q10 often locates in Mitochondria, soluble, Plasma membrane, Body tissue and Inner mitochondrial membrane. The associated genes with Coenzyme Q10 are MT-CYB gene, ATP5B gene, cytochrome c'', STN gene and NPC1 gene. The related lipids are Total cholesterol and Lipid Peroxides. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Coenzyme Q10, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coenzyme Q10?

Coenzyme Q10 is suspected in Heart failure, Myocardial Ischemia, COENZYME Q10 DEFICIENCY, Neurodegenerative Disorders, Myocardial Infarction, Glaucoma and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coenzyme Q10

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Neglected Diseases D058069 3 associated lipids
MELAS Syndrome D017241 3 associated lipids
Rare Diseases D035583 2 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with Coenzyme Q10

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coenzyme Q10?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Coenzyme Q10?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coenzyme Q10?

Related references are published most in these journals:

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What genes are associated with Coenzyme Q10?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coenzyme Q10?

Mouse Model

Mouse Model are used in the study 'Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage.' (Lulli M et al., 2012).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with Coenzyme Q10

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Authors Title Published Journal PubMed Link
Makabi-Panzu B et al. Coenzyme Q10 in vesicles composed of archaeal ether lipids or conventional lipids enhances the immuno-adjuvanticity to encapsulated protein. 1998 Vaccine pmid:9711796
Lin WY et al. Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia. 2008 Urology pmid:18280551
Moyad MA The placebo effect and randomized trials: analysis of alternative medicine. 2002 Urol. Clin. North Am. pmid:12109341
Potgieter M et al. Qualitative electron microscopic analysis of cultured chick embryonic cardiac and skeletal muscle cells: the cellular effect of coenzyme q10 after exposure to triton x-100. 2009 Ultrastruct Pathol pmid:19479649
Engelsen J et al. [Effect of Coenzyme Q10 and Ginkgo biloba on warfarin dosage in patients on long-term warfarin treatment. A randomized, double-blind, placebo-controlled cross-over trial]. 2003 Ugeskr. Laeg. pmid:12772396
Nielsen ML et al. [Reduced synthesis of coenzyme Q10 may cause statin related myopathy]. 2011 Ugeskr. Laeg. pmid:22094213
Vissinger H and Larsen ML [Statins and coenzyme Q10--idea or fact?]. 1994 Ugeskr. Laeg. pmid:8066843
Fjelstrup AO [Q10 deficiency--also at an oncologic department?]. 1994 Ugeskr. Laeg. pmid:8066916
[Can Q-10 be dangerous?]. 1993 Ugeskr. Laeg. pmid:8488607
Fjelstrup AO [Heart patients and uncritical cholesterol-inhibiting therapy using statins]. 1994 Ugeskr. Laeg. pmid:8009757
Cluis CP et al. Current prospects for the production of coenzyme Q10 in microbes. 2007 Trends Biotechnol. pmid:17935805
Extra co-enzyme Q10 for statin-users? 2001 TreatmentUpdate pmid:11570288
Complications and side effects. Health Canada warns about statin side effects. 2005 Jun-Jul TreatmentUpdate pmid:17228470
Nutrition and herbs. Cholesterol drug side effects may be linked to low nutrient levels. 2004 Jun-Jul TreatmentUpdate pmid:17219673
Wieland E et al. Idebenone protects hepatic microsomes against oxygen radical-mediated damage in organ preservation solutions. 1995 Transplantation pmid:7676491
Cho WH et al. Comparison of superoxide dismutase, allopurinol, coenzyme Q10, and glutathione for the prevention of warm ischemic injury. 1990 Transplantation pmid:2382304
Sehested J et al. Normal levels of coenzyme Q-10 in patients awaiting cardiac transplantation. 1993 Transplant. Proc. pmid:8516932
Fuchinoue S et al. Evaluation of intracellular energy status during liver preservation by 31P-NMR spectroscopy. 1988 Transplant. Proc. pmid:3347961
Marubayashi S et al. Protective effects of free radical scavenger and antioxidant administration on ischemic liver cell injury. 1987 Transplant. Proc. pmid:3274325
Marubayashi S et al. Effect of pretreatment with coenzyme Q10 and monoclonal antibodies to adhesion molecules on ischemic small intestine preservation. 1996 Transplant. Proc. pmid:8907970