Coenzyme Q10

Coenzyme q10 is a lipid of Prenol Lipids (PR) class. Coenzyme q10 is associated with abnormalities such as Nephrotic Syndrome, Diabetes, COENZYME Q10 DEFICIENCY, Deafness and Hypertensive disease. The involved functions are known as Mutation, Process, Oxidation, Electron Transport and Oxidants. Coenzyme q10 often locates in Mitochondria, soluble, Plasma membrane, Body tissue and Inner mitochondrial membrane. The associated genes with Coenzyme Q10 are MT-CYB gene, ATP5B gene, cytochrome c'', STN gene and NPC1 gene. The related lipids are Total cholesterol and Lipid Peroxides. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Coenzyme Q10, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coenzyme Q10?

Coenzyme Q10 is suspected in Heart failure, Myocardial Ischemia, COENZYME Q10 DEFICIENCY, Neurodegenerative Disorders, Myocardial Infarction, Glaucoma and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coenzyme Q10

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
MELAS Syndrome D017241 3 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Rare Diseases D035583 2 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Neglected Diseases D058069 3 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with Coenzyme Q10

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coenzyme Q10?

Related references are published most in these journals:

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What functions are associated with Coenzyme Q10?


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What lipids are associated with Coenzyme Q10?

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What genes are associated with Coenzyme Q10?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coenzyme Q10?

Mouse Model

Mouse Model are used in the study 'Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage.' (Lulli M et al., 2012).

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NCBI Entrez Crosslinks

All references with Coenzyme Q10

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Authors Title Published Journal PubMed Link
Gvozdjáková A et al. Coenzyme Q10 depletion and mitochondrial energy disturbances in rejection development in patients after heart transplantation. 1999 Biofactors pmid:10416044
Niibori K et al. Bioenergetic effect of liposomal coenzyme Q10 on myocardial ischemia reperfusion injury. 1999 Biofactors pmid:10416045
Eriksson JG et al. The effect of coenzyme Q10 administration on metabolic control in patients with type 2 diabetes mellitus. 1999 Biofactors pmid:10416046
Pedersen HS et al. High serum coenzyme Q10, positively correlated with age, selenium and cholesterol, in Inuit of Greenland. A pilot study. 1999 Biofactors pmid:10416047
Svegliati Baroni S et al. Monounsaturated diet lowers LDL oxidisability in type IIb and type IV dyslipidemia without affecting coenzyme Q10 and vitamin E contents. 1999 Biofactors pmid:10416048
Huertas JR et al. Virgin olive oil and coenzyme Q10 protect heart mitochondria from peroxidative damage during aging. 1999 Biofactors pmid:10416050
Barbieri B et al. Coenzyme Q10 administration increases antibody titer in hepatitis B vaccinated volunteers--a single blind placebo-controlled and randomized clinical study. 1999 Biofactors pmid:10416052
Willis R et al. Clinical implications of the correlation between coenzyme Q10 and vitamin B6 status. 1999 Biofactors pmid:10416053
Hodges S et al. CoQ10: could it have a role in cancer management? 1999 Biofactors pmid:10416054
Hoppe U et al. Coenzyme Q10, a cutaneous antioxidant and energizer. 1999 Biofactors pmid:10416055