Coenzyme Q10

Coenzyme q10 is a lipid of Prenol Lipids (PR) class. Coenzyme q10 is associated with abnormalities such as Nephrotic Syndrome, Diabetes, COENZYME Q10 DEFICIENCY, Deafness and Hypertensive disease. The involved functions are known as Mutation, Process, Oxidation, Electron Transport and Oxidants. Coenzyme q10 often locates in Mitochondria, soluble, Plasma membrane, Body tissue and Inner mitochondrial membrane. The associated genes with Coenzyme Q10 are MT-CYB gene, ATP5B gene, cytochrome c'', STN gene and NPC1 gene. The related lipids are Total cholesterol and Lipid Peroxides. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Coenzyme Q10, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coenzyme Q10?

Coenzyme Q10 is suspected in Heart failure, Myocardial Ischemia, COENZYME Q10 DEFICIENCY, Neurodegenerative Disorders, Myocardial Infarction, Glaucoma and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coenzyme Q10

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Body Weight D001835 333 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
MELAS Syndrome D017241 3 associated lipids
Neglected Diseases D058069 3 associated lipids
Rare Diseases D035583 2 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with Coenzyme Q10

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coenzyme Q10?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Coenzyme Q10?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coenzyme Q10?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Coenzyme Q10?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coenzyme Q10?

Mouse Model

Mouse Model are used in the study 'Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage.' (Lulli M et al., 2012).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Coenzyme Q10

Download all related citations
Per page 10 20 50 100 | Total 2646
Authors Title Published Journal PubMed Link
Ohta Y et al. Vitamin E depletion enhances liver oxidative damage in rats with water-immersion restraint stress. 2013 J. Nutr. Sci. Vitaminol. pmid:23727636
Kuimov AD and Murzina TA [Coenzyme q10 in complex therapy of patients with ischemic heart disease]. 2013 Kardiologiia pmid:24087999
Bhardwaj S et al. Muscular effects of statins in the elderly female: a review. 2013 Clin Interv Aging pmid:23355775
Sharanova NE et al. Effect of coenzyme Q10 on the proteomic profile of the cytosolic and microsomal fractions from rat hepatocytes upon dietary consumption of various lipid components during ontogeny. 2013 Bull. Exp. Biol. Med. pmid:23484191
Chen SW et al. Detection of suppressed maturation of the human COQ5 protein in the mitochondria following mitochondrial uncoupling by an antibody recognizing both precursor and mature forms of COQ5. 2013 Mitochondrion pmid:23354120
Estévez PN et al. Coenzyme Q10 stability in pediatric liquid oral dosage formulations. 2012 Nov-Dec Farm Hosp pmid:23461442
Ahmadvand H et al. Amelioration of altered antioxidant enzymes activity and glomerulosclerosis by coenzyme Q10 in alloxan-induced diabetic rats. 2012 Nov-Dec J. Diabetes Complicat. pmid:22795334
Gardner A Fibromyalgia: unknown pathogenesis and a "chicken or the egg" causality dilemma. 2012 Nov-Dec Nutrition pmid:22898266
Cordero MD et al. Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient. 2012 Nov-Dec Nutrition pmid:22898267
Lance J et al. Coenzyme Q10--a therapeutic agent. 2012 Nov-Dec Medsurg Nurs pmid:23477030
Brugè F et al. Olive oil supplemented with Coenzyme Q(10): effect on plasma and lipoprotein oxidative status. 2012 May-Jun Biofactors pmid:22488910
Yerramilli-Rao P et al. Oral repeated-dose toxicity studies of coenzyme Q10 in beagle dogs. 2012 Jan-Feb Int. J. Toxicol. pmid:22267890
Niklowitz P et al. Coenzyme Q10 concentration in plasma and blood cells of juvenile patients hospitalized for anorexia nervosa. 2012 Jan-Feb Biofactors pmid:22311849
Mikirova N et al. The assessment of the energy metabolism in patients with chronic fatigue syndrome by serum fluorescence emission. 2012 Jan-Feb Altern Ther Health Med pmid:22516851
Ferreiro-Barros CC et al. Determination of a method for extraction of coenzyme Q10 in human plasma: optimization of the use of surfactants and other variables. 2012 Apr-Jun Einstein (Sao Paulo) pmid:23052456
Marotta F et al. Biomarine extracts significantly protect from ultraviolet A-induced skin photoaging: an ex vivo study. 2012 Rejuvenation Res pmid:22533422
Park JM et al. Enhancing the production of Rhodobacter sphaeroides-derived physiologically active substances using carbonic anhydrase-immobilized electrospun nanofibers. 2012 Biomacromolecules pmid:22988895
Cluis CP et al. The production of coenzyme Q10 in microorganisms. 2012 Subcell. Biochem. pmid:23080257
Park J et al. Coenzyme Q10 protects neural stem cells against hypoxia by enhancing survival signals. 2012 Brain Res. pmid:23046589
Mikhin VP et al. [Efficacy of the use of coenzyme q10 at the background of traditional therapy of chronic ischemic heart disease]. 2012 Kardiologiia pmid:23098344
Mischley LK et al. Coenzyme Q10 deficiency in patients with Parkinson's disease. 2012 J. Neurol. Sci. pmid:22542608
Greenlee H et al. Lack of effect of coenzyme q10 on doxorubicin cytotoxicity in breast cancer cell cultures. 2012 Integr Cancer Ther pmid:22544232
Liu J et al. WITHDRAWN: Coenzyme Q10 for Parkinson's disease. 2012 Cochrane Database Syst Rev pmid:22592726
Turi A et al. Coenzyme Q10 content in follicular fluid and its relationship with oocyte fertilization and embryo grading. 2012 Arch. Gynecol. Obstet. pmid:22139446
Tran TP et al. Mitochondria-derived superoxide links to tourniquet-induced apoptosis in mouse skeletal muscle. 2012 PLoS ONE pmid:22912870
Safarinejad MR The effect of coenzyme Q₁₀ supplementation on partner pregnancy rate in infertile men with idiopathic oligoasthenoteratozoospermia: an open-label prospective study. 2012 Int Urol Nephrol pmid:22081410
Binukumar BK et al. Protective efficacy of coenzyme Q10 against DDVP-induced cognitive impairments and neurodegeneration in rats. 2012 Neurotox Res pmid:22083459
Tazato N et al. Gluconacetobacter tumulicola sp. nov. and Gluconacetobacter asukensis sp. nov., isolated from the stone chamber interior of the Kitora Tumulus. 2012 Int. J. Syst. Evol. Microbiol. pmid:22038998
Hickey MA et al. Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease. 2012 Mol. Cell. Neurosci. pmid:22044764
Niharika N et al. Sphingomonas indica sp. nov., isolated from hexachlorocyclohexane (HCH)-contaminated soil. 2012 Int. J. Syst. Evol. Microbiol. pmid:22307515
Persson MF et al. Coenzyme Q10 prevents GDP-sensitive mitochondrial uncoupling, glomerular hyperfiltration and proteinuria in kidneys from db/db mice as a model of type 2 diabetes. 2012 Diabetologia pmid:22311417
Felippi CC et al. Safety and efficacy of antioxidants-loaded nanoparticles for an anti-aging application. 2012 J Biomed Nanotechnol pmid:22515083
Zhang M et al. Coenzyme Q(10) enhances dermal elastin expression, inhibits IL-1α production and melanin synthesis in vitro. 2012 Int J Cosmet Sci pmid:22339577
Bravo E et al. Coenzyme Q metabolism is disturbed in high fat diet-induced non-alcoholic fatty liver disease in rats. 2012 Int J Mol Sci pmid:22408414
Lee BJ et al. Effects of coenzyme Q10 supplementation on inflammatory markers (high-sensitivity C-reactive protein, interleukin-6, and homocysteine) in patients with coronary artery disease. 2012 Nutrition pmid:22342390
Pfeffer G et al. Treatment for mitochondrial disorders. 2012 Cochrane Database Syst Rev pmid:22513923
Rahman S et al. 176th ENMC International Workshop: diagnosis and treatment of coenzyme Q₁₀ deficiency. 2012 Neuromuscul. Disord. pmid:21723727
Sica DA Nondrug interventions for the treatment of hypertension: varying effect. 2012 J Clin Hypertens (Greenwich) pmid:22235816
Spindler SR et al. Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation. 2012 PLoS ONE pmid:22737247
Mullin GE The heart speaks II: embracing integrative medicine for heart health. 2012 Nutr Clin Pract pmid:22820900
Okudan N et al. Effects of CoQ10 supplementation and swimming training on exhaustive exercise-induced oxidative stress in rat heart. 2012 Bratisl Lek Listy pmid:22794511
De Luca C et al. Coenzyme Q(10), vitamin E, selenium, and methionine in the treatment of chronic recurrent viral mucocutaneous infections. 2012 Nutrition pmid:22079390
Ostman B et al. Coenzyme Q10 supplementation and exercise-induced oxidative stress in humans. 2012 Nutrition pmid:22079391
Salviati L et al. Haploinsufficiency of COQ4 causes coenzyme Q10 deficiency. 2012 J. Med. Genet. pmid:22368301
Chirapapaisan N et al. The effect of coenzyme Q10 and curcumin on chronic methanol intoxication induced retinopathy in rats. 2012 J Med Assoc Thai pmid:22696856
Galasko DR et al. Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures. 2012 Arch. Neurol. pmid:22431837
Wagner AE et al. A combination of lipoic acid plus coenzyme Q10 induces PGC1α, a master switch of energy metabolism, improves stress response, and increases cellular glutathione levels in cultured C2C12 skeletal muscle cells. 2012 Oxid Med Cell Longev pmid:22655115
Sharanova NE et al. Effect of coenzyme Q10 on proteomic profile of blood plasma and cytosolic and microsomal fractions of rat hepatocytes during ontogeny. 2012 Bull. Exp. Biol. Med. pmid:23330083
Bergamini C et al. A water soluble CoQ10 formulation improves intracellular distribution and promotes mitochondrial respiration in cultured cells. 2012 PLoS ONE pmid:22432044
Seo MJ et al. Association of colony morphology with coenzyme Q(10) production and its enhancement from Rhizobium radiobacter T6102W by addition of isopentenyl alcohol as a precursor. 2012 J. Microbiol. Biotechnol. pmid:22370354