Coenzyme Q10

Coenzyme q10 is a lipid of Prenol Lipids (PR) class. Coenzyme q10 is associated with abnormalities such as Nephrotic Syndrome, Diabetes, COENZYME Q10 DEFICIENCY, Deafness and Hypertensive disease. The involved functions are known as Mutation, Process, Oxidation, Electron Transport and Oxidants. Coenzyme q10 often locates in Mitochondria, soluble, Plasma membrane, Body tissue and Inner mitochondrial membrane. The associated genes with Coenzyme Q10 are MT-CYB gene, ATP5B gene, cytochrome c'', STN gene and NPC1 gene. The related lipids are Total cholesterol and Lipid Peroxides. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Coenzyme Q10, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coenzyme Q10?

Coenzyme Q10 is suspected in Heart failure, Myocardial Ischemia, COENZYME Q10 DEFICIENCY, Neurodegenerative Disorders, Myocardial Infarction, Glaucoma and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coenzyme Q10

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Body Weight D001835 333 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
MELAS Syndrome D017241 3 associated lipids
Neglected Diseases D058069 3 associated lipids
Rare Diseases D035583 2 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with Coenzyme Q10

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coenzyme Q10?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Coenzyme Q10?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coenzyme Q10?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Coenzyme Q10?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coenzyme Q10?

Mouse Model

Mouse Model are used in the study 'Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage.' (Lulli M et al., 2012).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Coenzyme Q10

Download all related citations
Per page 10 20 50 100 | Total 2646
Authors Title Published Journal PubMed Link
Pereira R et al. Major regulatory mechanisms involved in sperm motility. 2017 Jan-Feb Asian J. Androl. pmid:26680031
Zaki ME et al. Coenzyme Q10 and pro-inflammatory markers in children with Down syndrome: clinical and biochemical aspects. 2017 Jan - Feb J Pediatr (Rio J) pmid:27770619
Banno H et al. Analysis of Participant Withdrawal in Huntington Disease Clinical Trials. 2017 J Huntingtons Dis pmid:28671136
Chen PY et al. Protective effect of Co-enzyme Q10 On doxorubicin-induced cardiomyopathy of rat hearts. 2017 Environ. Toxicol. pmid:27087047
Roese E and Bunjes H Drug release studies from lipid nanoparticles in physiological media by a new DSC method. 2017 J Control Release pmid:28450207
Li HN et al. Water-Soluble Coenzyme Q10 Reduces Rotenone-Induced Mitochondrial Fission. 2017 Neurochem. Res. pmid:28190227
Sheu SJ et al. Differential autophagic effects of vital dyes in retinal pigment epithelial ARPE-19 and photoreceptor 661W cells. 2017 PLoS ONE pmid:28358857
Jain S et al. α-Tocopherol as functional excipient for resveratrol and coenzyme Q10-loaded SNEDDS for improved bioavailability and prophylaxis of breast cancer. 2017 J Drug Target pmid:28274130
Guilbot A et al. A combination of coenzyme Q10, feverfew and magnesium for migraine prophylaxis: a prospective observational study. 2017 BMC Complement Altern Med pmid:28854909
Alehagen U et al. Increase in insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 1 after supplementation with selenium and coenzyme Q10. A prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens. 2017 PLoS ONE pmid:28609475
Alehagen U et al. Significant changes in circulating microRNA by dietary supplementation of selenium and coenzyme Q10 in healthy elderly males. A subgroup analysis of a prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens. 2017 PLoS ONE pmid:28448590
Ulla A et al. Coenzyme Q10 prevents oxidative stress and fibrosis in isoprenaline induced cardiac remodeling in aged rats. 2017 BMC Pharmacol Toxicol pmid:28427467
Ki Y et al. Effect of Coenzyme Q10 on Radiation Nephropathy in Rats. 2017 J. Korean Med. Sci. pmid:28378548
Garg S et al. CoQ10 selective miscibility and penetration into lipid monolayers with lower lateral packing density. 2017 Biochim. Biophys. Acta pmid:28366515
Lee SQ et al. Cellular factories for coenzyme Q10 production. 2017 Microb. Cell Fact. pmid:28253886
Varela-López A et al. Age-Related Loss in Bone Mineral Density of Rats Fed Lifelong on a Fish Oil-Based Diet Is Avoided by Coenzyme Q10 Addition. 2017 Nutrients pmid:28241421
Zhai J et al. Effects of Coenzyme Q10 on Markers of Inflammation: A Systematic Review and Meta-Analysis. 2017 PLoS ONE pmid:28125601
Awa H et al. Effects of Combined Treatment with Branched-Chain Amino Acids, Citric Acid, L-Carnitine, Coenzyme Q10, Zinc, and Various Vitamins in Tumor-Bearing Mice. 2017 Biol. Pharm. Bull. pmid:28123134
Liu HT et al. Coenzyme Q10 and Oxidative Stress: Inflammation Status in Hepatocellular Carcinoma Patients after Surgery. 2017 Nutrients pmid:28054958
Mustafa HN et al. Protective role of CoQ10 or L-carnitine on the integrity of the myocardium in doxorubicin induced toxicity. 2017 Tissue Cell pmid:28410798