Coenzyme Q10

Coenzyme q10 is a lipid of Prenol Lipids (PR) class. Coenzyme q10 is associated with abnormalities such as Nephrotic Syndrome, Diabetes, COENZYME Q10 DEFICIENCY, Deafness and Hypertensive disease. The involved functions are known as Mutation, Process, Oxidation, Electron Transport and Oxidants. Coenzyme q10 often locates in Mitochondria, soluble, Plasma membrane, Body tissue and Inner mitochondrial membrane. The associated genes with Coenzyme Q10 are MT-CYB gene, ATP5B gene, cytochrome c'', STN gene and NPC1 gene. The related lipids are Total cholesterol and Lipid Peroxides. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Coenzyme Q10, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coenzyme Q10?

Coenzyme Q10 is suspected in Heart failure, Myocardial Ischemia, COENZYME Q10 DEFICIENCY, Neurodegenerative Disorders, Myocardial Infarction, Glaucoma and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Coenzyme Q10

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Body Weight D001835 333 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
MELAS Syndrome D017241 3 associated lipids
Neglected Diseases D058069 3 associated lipids
Rare Diseases D035583 2 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Proteostasis Deficiencies D057165 5 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with Coenzyme Q10

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coenzyme Q10?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Coenzyme Q10?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coenzyme Q10?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Coenzyme Q10?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Coenzyme Q10?

Mouse Model

Mouse Model are used in the study 'Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage.' (Lulli M et al., 2012).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Coenzyme Q10

Download all related citations
Per page 10 20 50 100 | Total 2646
Authors Title Published Journal PubMed Link
Mao Z et al. Additive enhancement of wound healing in diabetic mice by low level light and topical CoQ10. 2016 Sci Rep pmid:26830658
Zhang YP et al. Acute Hypoglycemia Induces Painful Neuropathy and the Treatment of Coenzyme Q10. 2016 J Diabetes Res pmid:26824041
Barca E et al. Cerebellar ataxia and severe muscle CoQ10 deficiency in a patient with a novel mutation in ADCK3. 2016 Clin. Genet. pmid:26818466
Claessens AJ et al. Rapid and sensitive analysis of reduced and oxidized coenzyme Q10 in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and application to studies in healthy human subjects. 2016 Ann. Clin. Biochem. pmid:26056391
Asencio C et al. Severe encephalopathy associated to pyruvate dehydrogenase mutations and unbalanced coenzyme Q10 content. 2016 Eur. J. Hum. Genet. pmid:26014431
Takekawa Y et al. An Approach to Improve Intestinal Absorption of Poorly Absorbed Water-Insoluble Components via Niemann-Pick C1-Like 1. 2016 Biol. Pharm. Bull. pmid:26934923
Fišar Z et al. Effect of Simvastatin, Coenzyme Q10, Resveratrol, Acetylcysteine and Acetylcarnitine on Mitochondrial Respiration. 2016 Folia Biol. (Praha) pmid:27187037
Kim MK et al. Fluviicoccus keumensis gen. nov., sp. nov., isolated from freshwater. 2016 Int. J. Syst. Evol. Microbiol. pmid:26498187
Da Y et al. Successful treatment of periodic paralysis with coenzyme Q10: two case reports. 2016 Acta Myol pmid:28344441
Alehagen U et al. Supplementation with Selenium and Coenzyme Q10 Reduces Cardiovascular Mortality in Elderly with Low Selenium Status. A Secondary Analysis of a Randomised Clinical Trial. 2016 PLoS ONE pmid:27367855
Morrison JT et al. Effect of rosuvastatin on plasma coenzyme Q10 in HIV-infected individuals on antiretroviral therapy. 2016 HIV Clin Trials pmid:27294339
Özcan P et al. Can Coenzyme Q10 supplementation protect the ovarian reserve against oxidative damage? 2016 J. Assist. Reprod. Genet. pmid:27255570
Barca E et al. Decreased Coenzyme Q10 Levels in Multiple System Atrophy Cerebellum. 2016 J. Neuropathol. Exp. Neurol. pmid:27235405
Kumari S et al. Ubisol-Q10 Prevents Glutamate-Induced Cell Death by Blocking Mitochondrial Fragmentation and Permeability Transition Pore Opening. 2016 Int. J. Biol. Sci. pmid:27194946
Mirmalek SA et al. Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 on L-Arginine-Induced Acute Pancreatitis in Rat. 2016 Oxid Med Cell Longev pmid:27190575
Jenkins BJ et al. Characterization of a Plasmodium falciparum Orthologue of the Yeast Ubiquinone-Binding Protein, Coq10p. 2016 PLoS ONE pmid:27015086
Sharma A et al. Coenzyme Q10 and Heart Failure: A State-of-the-Art Review. 2016 Circ Heart Fail pmid:27012265
Barden A et al. n-3 Fatty Acid Supplementation and Leukocyte Telomere Length in Patients with Chronic Kidney Disease. 2016 Nutrients pmid:27007392
Cullen JK et al. AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation. 2016 PLoS ONE pmid:26866375
Higashi T et al. Improvement of Pharmaceutical Properties of Isoprenoid Compounds through the Formation of Cyclodextrin Pseudorotaxane-Like Supramolecules. 2016 Chem. Pharm. Bull. pmid:26852798