Coenzyme Q9

Coenzyme q9 is a lipid of Prenol Lipids (PR) class. The involved functions are known as Diastasis, Phosphorylation and Cardiac function.

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Introduction

To understand associated biological information of Coenzyme Q9, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Coenzyme Q9?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Coenzyme Q9

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Coenzyme Q9?

There are no associated biomedical information in the current reference collection.

What functions are associated with Coenzyme Q9?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Coenzyme Q9?

There are no associated biomedical information in the current reference collection.

What genes are associated with Coenzyme Q9?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Coenzyme Q9?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Coenzyme Q9

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Authors Title Published Journal PubMed Link
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Wang GS et al. Dietary iron overload inhibits carbon tetrachloride-induced promotion in chemical hepatocarcinogenesis: effects on cell proliferation, apoptosis, and antioxidation. 1999 J. Hepatol. pmid:10207812
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Mattila P et al. Comparison of in-line connected diode array and electrochemical detectors in the high-performance liquid chromatographic analysis of coenzymes Q(9) and Q(10) in food materials. 2000 J. Agric. Food Chem. pmid:10775376
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Cabrini L et al. Antioxidants and total peroxyl radical-trapping ability of olive and seed oils. 2001 J. Agric. Food Chem. pmid:11743803
Tatar M and Rand DM Aging. Dietary advice on Q. 2002 Science pmid:11778030
Larsen PL and Clarke CF Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q. 2002 Science pmid:11778046
Venditti P et al. H2O2 production and response to stress conditions by mitochondrial fractions from rat liver. 2002 J. Bioenerg. Biomembr. pmid:12018888
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Battino M et al. The effect of Cyclosporine A chronic administration on the antioxidant pattern of rat liver mitochondria: structural and functional consequences. 2003 Biofactors pmid:14695943
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Battino M et al. High-performance liquid chromatography-EC assay of mitochondrial coenzyme Q9, coenzyme Q9H2, coenzyme Q10, coenzyme Q10H2, and vitamin E with a simplified on-line solid-phase extraction. 2004 Meth. Enzymol. pmid:15038966
Khan SA Dehydroepiandrosterone sulfate increases hepatic ubiquinone-9 in male F-344 rats. 2004 Pharmazie pmid:15248468
Ebadi M et al. Coenzyme Q10 inhibits mitochondrial complex-1 down-regulation and nuclear factor-kappa B activation. 2004 Apr-Jun J. Cell. Mol. Med. pmid:15256069
Kayser EB et al. Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1. 2004 J. Biol. Chem. pmid:15269213
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Matsura T et al. Difference in antioxidant activity between reduced coenzyme Q9 and reduced coenzyme Q10 in the cell: studies with isolated rat and guinea pig hepatocytes treated with a water-soluble radical initiator. 1992 Biochim. Biophys. Acta pmid:1536870
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Kucharská J et al. Regeneration of coenzyme Q9 redox state and inhibition of oxidative stress by Rooibos tea (Aspalathus linearis) administration in carbon tetrachloride liver damage. 2004 Physiol Res pmid:15479130
Tang PH and deGrauw T Redox cycling of coenzyme Q9 as a new measure of plasma reducing power. 2004 Clin. Chem. pmid:15484328
Jun L et al. Identification and subcellular localization of two solanesyl diphosphate synthases from Arabidopsis thaliana. 2004 Plant Cell Physiol. pmid:15653808
Teshima K and Kondo T Analytical method for ubiquinone-9 and ubiquinone-10 in rat tissues by liquid chromatography/turbo ion spray tandem mass spectrometry with 1-alkylamine as an additive to the mobile phase. 2005 Anal. Biochem. pmid:15707930
Baxter RH et al. Cryogenic structure of the photosynthetic reaction center of Blastochloris viridis in the light and dark. 2005 Acta Crystallogr. D Biol. Crystallogr. pmid:15858271
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Johnson A et al. COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae. 2005 J. Biol. Chem. pmid:16027161
Bello RI et al. Enhanced anti-oxidant protection of liver membranes in long-lived rats fed on a coenzyme Q10-supplemented diet. 2005 Aug-Sep Exp. Gerontol. pmid:16125350
Novoselova EG [Lipid metabolism in rat tissues during chronic gamma-irradiation and action of ubiquinone Q-9]. 1992 Biokhimiia pmid:1637916
Yan J et al. Reduced coenzyme Q10 supplementation decelerates senescence in SAMP1 mice. 2006 Exp. Gerontol. pmid:16387461
Takahashi S et al. Metabolic engineering of coenzyme Q by modification of isoprenoid side chain in plant. 2006 FEBS Lett. pmid:16442107
Arroyo A et al. Coenzyme Q is irreplaceable by demethoxy-coenzyme Q in plasma membrane of Caenorhabditis elegans. 2006 FEBS Lett. pmid:16504181
Smith KM et al. Dose ranging and efficacy study of high-dose coenzyme Q10 formulations in Huntington's disease mice. 2006 Biochim. Biophys. Acta pmid:16647250
Quiles JL et al. Life-long supplementation with a low dosage of coenzyme Q10 in the rat: effects on antioxidant status and DNA damage. 2005 Biofactors pmid:16873932
Afzal M et al. CoQ9 potentiates green tea antioxidant activities in Wistar rats. 2005 Biofactors pmid:16873954
Zahiri HS et al. Biochemical characterization of the decaprenyl diphosphate synthase of Rhodobacter sphaeroides for coenzyme Q10 production. 2006 Appl. Microbiol. Biotechnol. pmid:16896603
Yoshida Y et al. Evaluation of the dietary effects of coenzyme Q in vivo by the oxidative stress marker, hydroxyoctadecadienoic acid and its stereoisomer ratio. 2006 Biochim. Biophys. Acta pmid:16908102
Ferella M et al. A solanesyl-diphosphate synthase localizes in glycosomes of Trypanosoma cruzi. 2006 J. Biol. Chem. pmid:17062572
Hermans N et al. Study of potential systemic oxidative stress animal models for the evaluation of antioxidant activity: status of lipid peroxidation and fat-soluble antioxidants. 2007 J. Pharm. Pharmacol. pmid:17227630
Hsieh EJ et al. Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex. 2007 Arch. Biochem. Biophys. pmid:17391640
Molyneux S et al. Plasma total coenzyme Q9 (CoQ9) in the New Zealand population: reference interval and biological variation. 2007 Clin. Chem. pmid:17405953
Martin SF et al. Coenzyme Q and protein/lipid oxidation in a BSE-infected transgenic mouse model. 2007 Free Radic. Biol. Med. pmid:17462540
Santos-González M et al. Modifications of plasma proteome in long-lived rats fed on a coenzyme Q10-supplemented diet. 2007 Exp. Gerontol. pmid:17587521
Lu J and Frank EL Measurement of coenzyme Q10 in clinical practice. 2007 Clin. Chim. Acta pmid:17689513
Kucharská J et al. Simvastatin decreased coenzyme Q in the left ventricle and skeletal muscle but not in the brain and liver in L-NAME-induced hypertension. 2007 Physiol Res pmid:17824807
Shelley P et al. Rapid neonatal weight gain in rats results in a renal ubiquinone (CoQ) deficiency associated with premature death. 2007 Nov-Dec Mech. Ageing Dev. pmid:18035399
Li L et al. Analysis of CoQ10 in rat serum by ultra-performance liquid chromatography mass spectrometry after oral administration. 2008 J Pharm Biomed Anal pmid:18054195
Kocsis GF et al. Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18359895
Matejíková J et al. The effect of antioxidant treatment and NOS inhibition on the incidence of ischemia-induced arrhythmias in the diabetic rat heart. 2008 Physiol Res pmid:18373392
Kiebish MA et al. Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria. 2008 J. Neurochem. pmid:18373617
Lekli I et al. Coenzyme Q9 provides cardioprotection after converting into coenzyme Q10. 2008 J. Agric. Food Chem. pmid:18543930
Rodríguez-Acuña R et al. Determination of coenzyme Q10 and Q9 in vegetable oils. 2008 J. Agric. Food Chem. pmid:18616270
Saiki R et al. Coenzyme Q10 supplementation rescues renal disease in Pdss2kd/kd mice with mutations in prenyl diphosphate synthase subunit 2. 2008 Am. J. Physiol. Renal Physiol. pmid:18784258
Huertas JR et al. Changes in mitochondrial and microsomal rat liver coenzyme Q9 and Q10 content induced by dietary fat and endogenous lipid peroxidation. 1991 FEBS Lett. pmid:1879539
Asencio C et al. Coenzyme Q supports distinct developmental processes in Caenorhabditis elegans. 2009 Mech. Ageing Dev. pmid:19007804
Acworth IN et al. Determination of oxidized and reduced CoQ10 and CoQ9 in human plasma/serum using HPLC-ECD. 2008 Methods Mol. Biol. pmid:19082952
Imada I et al. Effect of CoQ homologues on reactive oxygen generation by mitochondria. 2008 Biofactors pmid:19096099
Yoshida Y et al. The role of alpha-tocopherol in motor hypofunction with aging in alpha-tocopherol transfer protein knockout mice as assessed by oxidative stress biomarkers. 2010 J. Nutr. Biochem. pmid:19157826
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Duncan AJ et al. A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: a potentially treatable form of mitochondrial disease. 2009 Am. J. Hum. Genet. pmid:19375058
Yang YY et al. The effect of different ubiquinones on lifespan in Caenorhabditis elegans. 2009 Mech. Ageing Dev. pmid:19428456
Shelley P et al. Altered skeletal muscle insulin signaling and mitochondrial complex II-III linked activity in adult offspring of obese mice. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19535678
Cano A et al. Hepatic VLDL assembly is disturbed in a rat model of nonalcoholic fatty liver disease: is there a role for dietary coenzyme Q? 2009 J. Appl. Physiol. pmid:19608932
Bae JS et al. Apoptotic cell death of human leukaemia U937 cells by ubiquinone-9 purified from Pleurotus eryngii. 2009 Nat. Prod. Res. pmid:19662576
Sumien N et al. Prolonged intake of coenzyme Q10 impairs cognitive functions in mice. 2009 J. Nutr. pmid:19710165
Bebrevska L et al. In vivo antioxidative activity of a quantified Pueraria lobata root extract. 2010 J Ethnopharmacol pmid:19799984
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Matsura T et al. Changes in the content and intracellular distribution of coenzyme Q homologs in rabbit liver during growth. 1991 Biochim. Biophys. Acta pmid:2049392
Kohli R et al. High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. 2010 Hepatology pmid:20607689
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Bauerova K et al. Combined methotrexate and coenzyme Q₁₀ therapy in adjuvant-induced arthritis evaluated using parameters of inflammation and oxidative stress. 2010 Acta Biochim. Pol. pmid:20827446
Vasta V et al. Altered redox status of coenzyme Q9 reflects mitochondrial electron transport chain deficiencies in Caenorhabditis elegans. 2011 Mitochondrion pmid:20849980
Parrado-Fernández C et al. Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues. 2011 Free Radic. Biol. Med. pmid:21447381
Nishi K et al. Hypothermia reduces resuscitation fluid volumes required to maintain blood pressure in a rat hemorrhagic shock model. 2012 J Trauma Acute Care Surg pmid:21768895
Ducluzeau AL et al. Gene network reconstruction identifies the authentic trans-prenyl diphosphate synthase that makes the solanesyl moiety of ubiquinone-9 in Arabidopsis. 2012 Plant J. pmid:21950843
Venegas C et al. Determination of coenzyme Q10, coenzyme Q9, and melatonin contents in virgin argan oils: comparison with other edible vegetable oils. 2011 J. Agric. Food Chem. pmid:22007968
Wang QM et al. Bensingtonia rectispora sp. nov. and Bensingtonia bomiensis sp. nov., ballistoconidium-forming yeast species from Tibetan plant leaves. 2012 Int. J. Syst. Evol. Microbiol. pmid:22081720
Hahn SH et al. Assay to measure oxidized and reduced forms of CoQ by LC-MS/MS. 2012 Methods Mol. Biol. pmid:22215547