alpha-tocopherol

Alpha-tocopherol is a lipid of Prenol Lipids (PR) class. Alpha-tocopherol is associated with abnormalities such as Cerebrovascular accident and Cardiovascular Diseases. The involved functions are known as Metabolic Inhibition, Pharmacodynamics, Platelet Adhesiveness and pseudopodium assembly. Alpha-tocopherol often locates in Membrane. The related lipids are Membrane Lipids.

Cross Reference

Introduction

To understand associated biological information of alpha-tocopherol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with alpha-tocopherol?

alpha-tocopherol is suspected in Cerebrovascular accident, Cardiovascular Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-tocopherol

MeSH term MeSH ID Detail
Vitamin E Deficiency D014811 29 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with alpha-tocopherol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with alpha-tocopherol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with alpha-tocopherol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with alpha-tocopherol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with alpha-tocopherol?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with alpha-tocopherol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with alpha-tocopherol

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Authors Title Published Journal PubMed Link
Song J et al. TPGS/Phospholipids Mixed Micelles for Delivery of Icariside II to Multidrug-Resistant Breast Cancer. 2016 Integr Cancer Ther pmid:26293804
Kumral A et al. Beneficial effects of carnosine and carnosine plus vitamin E treatments on doxorubicin-induced oxidative stress and cardiac, hepatic, and renal toxicity in rats. 2016 Hum Exp Toxicol pmid:26224044
Kim Y et al. Suppression of NLRP3 inflammasome by γ-tocotrienol ameliorates type 2 diabetes. 2016 J. Lipid Res. pmid:26628639
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Satué M et al. Improved human gingival fibroblast response to titanium implants coated with ultraviolet-irradiated vitamin D precursor and vitamin E. 2016 J. Periodont. Res. pmid:26271967
Cheng X et al. Preparation and in vivo/in vitro evaluation of formononetin phospholipid/vitamin E TPGS micelles. 2016 J Drug Target pmid:26325229
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Ha ES et al. Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process. 2015 Drug Des Devel Ther pmid:26345723
Ebokaiwe AP and Farombi EO Influence of vitamin E and quercetin on Nigerian Bonny Light crude oil-induced neuronal and testicular toxicity in Wistar rats. 2015 J Basic Clin Physiol Pharmacol pmid:25046308
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Sugahara R et al. Annatto Tocotrienol Induces a Cytotoxic Effect on Human Prostate Cancer PC3 Cells via the Simultaneous Inhibition of Src and Stat3. 2015 J. Nutr. Sci. Vitaminol. pmid:26875492
Springett GM et al. A Phase I Safety, Pharmacokinetic, and Pharmacodynamic Presurgical Trial of Vitamin E δ-tocotrienol in Patients with Pancreatic Ductal Neoplasia. 2015 EBioMedicine pmid:26844278
Meganathan P et al. A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to existing Tocotrienol-Rich Fraction in healthy human subjects. 2015 Sci Rep pmid:26323969
Kim EH et al. Fibrillin 5 Is Essential for Plastoquinone-9 Biosynthesis by Binding to Solanesyl Diphosphate Synthases in Arabidopsis. 2015 Plant Cell pmid:26432861
Parajuli P et al. Anticancer Effects of γ-Tocotrienol Are Associated with a Suppression in Aerobic Glycolysis. 2015 Biol. Pharm. Bull. pmid:26328490
Gu W et al. Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway. 2015 BMC Cancer pmid:26315028
Abdel-Hamid AA and Firgany Ael-D Vitamin E supplementation ameliorates aflatoxin B1-induced nephrotoxicity in rats. 2015 Acta Histochem. pmid:26315992
Ni Y et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. 2015 Sci Rep pmid:26603489
Apostolidou C et al. Alterations of antioxidant status in asymptomatic hypercholesterolemic individuals after resveratrol intake. 2015 Int J Food Sci Nutr pmid:27108746
Demirci H et al. Influence of vitamin C and E supplementation on the eradication rates of triple and quadruple eradication regimens for Helicobacter pylori infection. 2015 Turk J Gastroenterol pmid:26510082