delta-tocotrienol

Delta-tocotrienol is a lipid of Prenol Lipids (PR) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 456 references associated with delta-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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We collected disease MeSH terms mapped to the references associated with delta-tocotrienol

MeSH term MeSH ID Detail
Weight Gain D015430 101 associated lipids
Total 1

PubChem Biomolecular Interactions and Pathways

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Hayes KC et al. Differences in the plasma transport and tissue concentrations of tocopherols and tocotrienols: observations in humans and hamsters. 1993 Proc. Soc. Exp. Biol. Med. pmid:8437992
Guthrie N et al. Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. 1997 J. Nutr. pmid:9082043
Kamat JP et al. Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes. 1997 Mol. Cell. Biochem. pmid:9144327
Yu W et al. Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. 1999 Nutr Cancer pmid:10227040
Katsanidis E and Addis PB Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue. 1999 Free Radic. Biol. Med. pmid:10641704
Black TM et al. Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. 2000 J. Nutr. pmid:11015467
Sylvester PW et al. Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation. 2001 Cell Prolif. pmid:11736999
Nakamura H et al. Oral toxicity of a tocotrienol preparation in rats. 2001 Food Chem. Toxicol. pmid:11434987
Yap SP et al. Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status. 2001 J. Pharm. Pharmacol. pmid:11206194
Seo EK et al. Cytotoxic prenylated xanthones and the unusual compounds anthraquinobenzophenones from Cratoxylum sumatranum. 2002 J. Nat. Prod. pmid:11908969
Chao JT et al. Inhibitory effect of delta-tocotrienol, a HMG CoA reductase inhibitor, on monocyte-endothelial cell adhesion. 2002 J. Nutr. Sci. Vitaminol. pmid:12656204
Yap SP et al. Influence of route of administration on the absorption and disposition of alpha-, gamma- and delta-tocotrienols in rats. 2003 J. Pharm. Pharmacol. pmid:12625867
Anderson SL et al. Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia. 2003 Biochem. Biophys. Res. Commun. pmid:12788105
Yap SP and Yuen KH Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations. 2004 Int J Pharm pmid:15288344
Zhou C et al. Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. 2004 Drug Metab. Dispos. pmid:15269186
Shun MC et al. Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells. 2004 Nutr Cancer pmid:15203383
Sakai M et al. Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells. 2006 J. Nutr. Biochem. pmid:16517139
Song BL and DeBose-Boyd RA Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols. 2006 J. Biol. Chem. pmid:16831864
Couladouros EA et al. A short and convenient chemical route to optically pure 2-methyl chromanmethanols. Total asymmetric synthesis of beta-, gamma-, and delta-tocotrienols. 2007 J. Org. Chem. pmid:17685653
Ung CY et al. In silico prediction of pregnane X receptor activators by machine learning approaches. 2007 Mol. Pharmacol. pmid:17003167
Harinantenaina L et al. Cinnamacrins A-C, cinnafragrin D, and cytostatic metabolites with alpha-glucosidase inhibitory activity from Cinnamosma macrocarpa. 2007 J. Nat. Prod. pmid:17286431
Albermann C et al. Biosynthesis of the vitamin E compound delta-tocotrienol in recombinant Escherichia coli cells. 2008 Chembiochem pmid:18810749
El Sayed KA et al. Semisynthetic and biotransformation studies of (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol. 2008 J. Nat. Prod. pmid:18177013
Shibata A et al. Tumor anti-angiogenic effect and mechanism of action of delta-tocotrienol. 2008 Biochem. Pharmacol. pmid:18599020
Elangovan S et al. Growth inhibition of human MDA-mB-231 breast cancer cells by delta-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product. 2008 Sep-Oct Anticancer Res. pmid:19035289
Hiura Y et al. Specific accumulation of gamma- and delta-tocotrienols in tumor and their antitumor effect in vivo. 2009 J. Nutr. Biochem. pmid:18824342
Shibata A et al. delta-Tocotrienol suppresses VEGF induced angiogenesis whereas alpha-tocopherol does not. 2009 J. Agric. Food Chem. pmid:19702331