MeSH term | MeSH ID | Detail |
---|---|---|
Weight Gain | D015430 | 101 associated lipids |
Total
1
Delta-tocotrienol is a lipid of Prenol Lipids (PR) class.
We collected disease MeSH terms mapped to the references associated with delta-tocotrienol
MeSH term | MeSH ID | Detail |
---|---|---|
Weight Gain | D015430 | 101 associated lipids |
Authors | Title | Published | Journal | PubMed Link |
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Eitsuka T et al. | A Combination of δ-Tocotrienol and Ferulic Acid Synergistically Inhibits Telomerase Activity in DLD-1 Human Colorectal Adenocarcinoma Cells. | 2016 | J. Nutr. Sci. Vitaminol. | pmid:27928113 |
Mahipal A et al. | Pharmacokinetics and safety of vitamin E δ-tocotrienol after single and multiple doses in healthy subjects with measurement of vitamin E metabolites. | 2016 | Cancer Chemother. Pharmacol. | pmid:27278668 |
Zhao L et al. | Regulation of Obesity and Metabolic Complications by Gamma and Delta Tocotrienols. | 2016 | Molecules | pmid:26978344 |
Sugahara R et al. | Annatto Tocotrienol Induces a Cytotoxic Effect on Human Prostate Cancer PC3 Cells via the Simultaneous Inhibition of Src and Stat3. | 2015 | J. Nutr. Sci. Vitaminol. | pmid:26875492 |
Springett GM et al. | A Phase I Safety, Pharmacokinetic, and Pharmacodynamic Presurgical Trial of Vitamin E δ-tocotrienol in Patients with Pancreatic Ductal Neoplasia. | 2015 | EBioMedicine | pmid:26844278 |
Meganathan P et al. | A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to existing Tocotrienol-Rich Fraction in healthy human subjects. | 2015 | Sci Rep | pmid:26323969 |
Wang C et al. | EGR-1/Bax pathway plays a role in vitamin E δ-tocotrienol-induced apoptosis in pancreatic cancer cells. | 2015 | J. Nutr. Biochem. | pmid:25997867 |
Ye C et al. | δ-tocotrienol induces human bladder cancer cell growth arrest, apoptosis and chemosensitization through inhibition of STAT3 pathway. | 2015 | PLoS ONE | pmid:25849286 |
Li XH et al. | Delta-tocotrienol suppresses radiation-induced microRNA-30 and protects mice and human CD34+ cells from radiation injury. | 2015 | PLoS ONE | pmid:25815474 |
Hsu PY and Yang YW | Gene delivery via the hybrid vector of recombinant adeno-associated virus and polyethylenimine. | 2014 | Eur J Pharm Sci | pmid:24184196 |
Lim SW et al. | Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells. | 2014 | BMC Complement Altern Med | pmid:25480449 |
Ananthula S et al. | δ-Tocotrienol oxazine derivative antagonizes mammary tumor cell compensatory response to CoCl2-induced hypoxia. | 2014 | Biomed Res Int | pmid:25140303 |
Haleagrahara N et al. | Therapeutic efficacy of vitamin E δ-tocotrienol in collagen-induced rat model of arthritis. | 2014 | Biomed Res Int | pmid:25114906 |
Ananthula S et al. | Oxazine derivatives of γ- and δ-tocotrienol display enhanced anticancer activity in vivo. | 2014 | Anticancer Res. | pmid:24922632 |
Singh VK et al. | Radioprotective efficacy of delta-tocotrienol, a vitamin E isoform, is mediated through granulocyte colony-stimulating factor. | 2014 | Life Sci. | pmid:24486300 |
Viola V et al. | Mitochondrial-dependent anticancer activity of δ-tocotrienol and its synthetic derivatives in HER-2/neu overexpressing breast adenocarcinoma cells. | 2013 Jul-Aug | Biofactors | pmid:23361894 |
Rodzian MN et al. | Pure tocotrienol concentrate protected rat gastric mucosa from acute stress-induced injury by a non-antioxidant mechanism. | 2013 | Pol J Pathol | pmid:23625601 |
Behery FA et al. | Optimization of tocotrienols as antiproliferative and antimigratory leads. | 2013 | Eur J Med Chem | pmid:23274571 |
Hodul PJ et al. | Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism. | 2013 | PLoS ONE | pmid:23393547 |
Husain K et al. | Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E δ-tocotrienol. | 2013 | Carcinogenesis | pmid:23302291 |
Li XH et al. | Delta-tocotrienol protects mice from radiation-induced gastrointestinal injury. | 2013 | Radiat. Res. | pmid:24294967 |
Husain K et al. | Vitamin E δ-tocotrienol prolongs survival in the LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) transgenic mouse model of pancreatic cancer. | 2013 | Cancer Prev Res (Phila) | pmid:23963802 |
Loganathan R et al. | Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity. | 2013 | Cell Prolif. | pmid:23510475 |
Qureshi AA et al. | Nutritional Supplement-5 with a Combination of Proteasome Inhibitors (Resveratrol, Quercetin, δ-Tocotrienol) Modulate Age-Associated Biomarkers and Cardiovascular Lipid Parameters in Human Subjects. | 2013 | J Clin Exp Cardiolog | pmid:24319627 |
Forster GM et al. | Rice varietal differences in bioactive bran components for inhibition of colorectal cancer cell growth. | 2013 | Food Chem | pmid:23790950 |
Constantinou C et al. | Induction of DNA damage and caspase-independent programmed cell death by vitamin E. | 2012 | Nutr Cancer | pmid:22172208 |
Wong RS et al. | δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells. | 2012 | Microsc. Microanal. | pmid:22640960 |
Ji X et al. | Delta-tocotrienol augments cisplatin-induced suppression of non-small cell lung cancer cells via inhibition of the Notch-1 pathway. | 2012 | Anticancer Res. | pmid:22753722 |
Satyamitra M et al. | Mechanism of radioprotection by δ-tocotrienol: pharmacokinetics, pharmacodynamics and modulation of signalling pathways. | 2012 | Br J Radiol | pmid:22674714 |
Yue MA et al. | [Experimental study on delta-tocotrienol inhibits the Wnt pathway in the colon cancer cell SW620]. | 2012 | Wei Sheng Yan Jiu | pmid:23424864 |
Ji X et al. | Delta-tocotrienol suppresses Notch-1 pathway by upregulating miR-34a in nonsmall cell lung cancer cells. | 2012 | Int. J. Cancer | pmid:22438124 |
Krycer JR et al. | A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products. | 2012 | Biochem. J. | pmid:22657538 |
Katuru R et al. | Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. | 2011 | Exp. Biol. Med. (Maywood) | pmid:21540247 |
Tan SW et al. | Inhibitory effects of palm α-, γ- and δ-tocotrienol on lipopolysaccharide-induced nitric oxide production in BV2 microglia. | 2011 | Cell. Immunol. | pmid:21839427 |
Satyamitra MM et al. | Hematopoietic Recovery and Amelioration of Radiation-Induced Lethality by the Vitamin E Isoform δ-Tocotrienol. | 2011 | Radiat. Res. | pmid:21434782 |
Zhang JS et al. | A paraptosis-like cell death induced by δ-tocotrienol in human colon carcinoma SW620 cells is associated with the suppression of the Wnt signaling pathway. | 2011 | Toxicology | pmid:21453743 |
Chen J et al. | Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cyclic GMP/protein kinase G signaling in cardiac fibroblasts. | 2011 | Circulation | pmid:21282499 |
Ji X et al. | Inhibition of cell growth and induction of apoptosis in non-small cell lung cancer cells by delta-tocotrienol is associated with notch-1 down-regulation. | 2011 | J. Cell. Biochem. | pmid:21598300 |
Qureshi AA et al. | Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by δ-tocotrienol and quercetin. | 2011 | Lipids Health Dis | pmid:22185406 |
Husain K et al. | Vitamin E δ-tocotrienol augments the antitumor activity of gemcitabine and suppresses constitutive NF-κB activation in pancreatic cancer. | 2011 | Mol. Cancer Ther. | pmid:21971120 |
Brooks R et al. | Direct inhibition of osteoclast formation and activity by the vitamin E isomer gamma-tocotrienol. | 2011 | Int J Vitam Nutr Res | pmid:22673919 |
Qureshi AA et al. | δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens. | 2011 | Lipids Health Dis | pmid:21356098 |
Pierpaoli E et al. | Gamma- and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression. | 2010 | Life Sci. | pmid:20188744 |
Li F et al. | Tocotrienol enriched palm oil prevents atherosclerosis through modulating the activities of peroxisome proliferators-activated receptors. | 2010 | Atherosclerosis | pmid:20138624 |
Zaiden N et al. | Gamma delta tocotrienols reduce hepatic triglyceride synthesis and VLDL secretion. | 2010 | J. Atheroscler. Thromb. | pmid:20702976 |
Li XH et al. | Delta-tocotrienol protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling. | 2010 | Haematologica | pmid:20823133 |
Michihara A et al. | Effect of δ-tocotrienol on melanin content and enzymes for melanin synthesis in mouse melanoma cells. | 2010 | Biol. Pharm. Bull. | pmid:20823559 |
Mudit M et al. | Synthesis of fluorescent analogues of the anticancer natural products 4-hydroxyphenylmethylene hydantoin and delta-tocotrienol. | 2010 | Nat Prod Commun | pmid:21121261 |
Fernandes NV et al. | d-δ-Tocotrienol-mediated cell cycle arrest and apoptosis in human melanoma cells. | 2010 | Anticancer Res. | pmid:21187473 |
Yap WN et al. | Gamma- and delta-tocotrienols inhibit skin melanin synthesis by suppressing constitutive and UV-induced tyrosinase activation. | 2010 | Pigment Cell Melanoma Res | pmid:20609176 |
Shibata A et al. | alpha-Tocopherol attenuates the cytotoxic effect of delta-tocotrienol in human colorectal adenocarcinoma cells. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20493172 |
Hiura Y et al. | Specific accumulation of gamma- and delta-tocotrienols in tumor and their antitumor effect in vivo. | 2009 | J. Nutr. Biochem. | pmid:18824342 |
Shibata A et al. | delta-Tocotrienol suppresses VEGF induced angiogenesis whereas alpha-tocopherol does not. | 2009 | J. Agric. Food Chem. | pmid:19702331 |
Husain K et al. | Vitamin E delta-tocotrienol levels in tumor and pancreatic tissue of mice after oral administration. | 2009 | Pharmacology | pmid:19142032 |
Constantinou C et al. | Induction of caspase-independent programmed cell death by vitamin E natural homologs and synthetic derivatives. | 2009 | Nutr Cancer | pmid:20155628 |
Mazzini F et al. | Configuration of the vitamin E analogue garcinoic acid extracted from Garcinia Kola seeds. | 2009 | Chirality | pmid:18655162 |
Elangovan S et al. | Growth inhibition of human MDA-mB-231 breast cancer cells by delta-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product. | 2008 Sep-Oct | Anticancer Res. | pmid:19035289 |
Albermann C et al. | Biosynthesis of the vitamin E compound delta-tocotrienol in recombinant Escherichia coli cells. | 2008 | Chembiochem | pmid:18810749 |
El Sayed KA et al. | Semisynthetic and biotransformation studies of (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol. | 2008 | J. Nat. Prod. | pmid:18177013 |
Shibata A et al. | Tumor anti-angiogenic effect and mechanism of action of delta-tocotrienol. | 2008 | Biochem. Pharmacol. | pmid:18599020 |
Couladouros EA et al. | A short and convenient chemical route to optically pure 2-methyl chromanmethanols. Total asymmetric synthesis of beta-, gamma-, and delta-tocotrienols. | 2007 | J. Org. Chem. | pmid:17685653 |
Ung CY et al. | In silico prediction of pregnane X receptor activators by machine learning approaches. | 2007 | Mol. Pharmacol. | pmid:17003167 |
Harinantenaina L et al. | Cinnamacrins A-C, cinnafragrin D, and cytostatic metabolites with alpha-glucosidase inhibitory activity from Cinnamosma macrocarpa. | 2007 | J. Nat. Prod. | pmid:17286431 |
Sakai M et al. | Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells. | 2006 | J. Nutr. Biochem. | pmid:16517139 |
Song BL and DeBose-Boyd RA | Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols. | 2006 | J. Biol. Chem. | pmid:16831864 |
Yap SP and Yuen KH | Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations. | 2004 | Int J Pharm | pmid:15288344 |
Zhou C et al. | Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. | 2004 | Drug Metab. Dispos. | pmid:15269186 |
Shun MC et al. | Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells. | 2004 | Nutr Cancer | pmid:15203383 |
Yap SP et al. | Influence of route of administration on the absorption and disposition of alpha-, gamma- and delta-tocotrienols in rats. | 2003 | J. Pharm. Pharmacol. | pmid:12625867 |
Anderson SL et al. | Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12788105 |
Seo EK et al. | Cytotoxic prenylated xanthones and the unusual compounds anthraquinobenzophenones from Cratoxylum sumatranum. | 2002 | J. Nat. Prod. | pmid:11908969 |
Chao JT et al. | Inhibitory effect of delta-tocotrienol, a HMG CoA reductase inhibitor, on monocyte-endothelial cell adhesion. | 2002 | J. Nutr. Sci. Vitaminol. | pmid:12656204 |
Sylvester PW et al. | Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation. | 2001 | Cell Prolif. | pmid:11736999 |
Nakamura H et al. | Oral toxicity of a tocotrienol preparation in rats. | 2001 | Food Chem. Toxicol. | pmid:11434987 |
Yap SP et al. | Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status. | 2001 | J. Pharm. Pharmacol. | pmid:11206194 |
Black TM et al. | Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. | 2000 | J. Nutr. | pmid:11015467 |
Yu W et al. | Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. | 1999 | Nutr Cancer | pmid:10227040 |
Katsanidis E and Addis PB | Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue. | 1999 | Free Radic. Biol. Med. | pmid:10641704 |
Guthrie N et al. | Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. | 1997 | J. Nutr. | pmid:9082043 |
Kamat JP et al. | Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes. | 1997 | Mol. Cell. Biochem. | pmid:9144327 |
Hayes KC et al. | Differences in the plasma transport and tissue concentrations of tocopherols and tocotrienols: observations in humans and hamsters. | 1993 | Proc. Soc. Exp. Biol. Med. | pmid:8437992 |
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