| MeSH term | MeSH ID | Detail |
|---|---|---|
| Weight Gain | D015430 | 101 associated lipids |
Total
1
delta-tocotrienol
Delta-tocotrienol is a lipid of Prenol Lipids (PR) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 456 references associated with delta-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for delta-tocotrienol
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with delta-tocotrienol
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with delta-tocotrienol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Eitsuka T et al. | A Combination of δ-Tocotrienol and Ferulic Acid Synergistically Inhibits Telomerase Activity in DLD-1 Human Colorectal Adenocarcinoma Cells. | 2016 | J. Nutr. Sci. Vitaminol. | pmid:27928113 |
| Mahipal A et al. | Pharmacokinetics and safety of vitamin E δ-tocotrienol after single and multiple doses in healthy subjects with measurement of vitamin E metabolites. | 2016 | Cancer Chemother. Pharmacol. | pmid:27278668 |
| Zhao L et al. | Regulation of Obesity and Metabolic Complications by Gamma and Delta Tocotrienols. | 2016 | Molecules | pmid:26978344 |
| Sugahara R et al. | Annatto Tocotrienol Induces a Cytotoxic Effect on Human Prostate Cancer PC3 Cells via the Simultaneous Inhibition of Src and Stat3. | 2015 | J. Nutr. Sci. Vitaminol. | pmid:26875492 |
| Springett GM et al. | A Phase I Safety, Pharmacokinetic, and Pharmacodynamic Presurgical Trial of Vitamin E δ-tocotrienol in Patients with Pancreatic Ductal Neoplasia. | 2015 | EBioMedicine | pmid:26844278 |
| Meganathan P et al. | A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to existing Tocotrienol-Rich Fraction in healthy human subjects. | 2015 | Sci Rep | pmid:26323969 |
| Wang C et al. | EGR-1/Bax pathway plays a role in vitamin E δ-tocotrienol-induced apoptosis in pancreatic cancer cells. | 2015 | J. Nutr. Biochem. | pmid:25997867 |
| Ye C et al. | δ-tocotrienol induces human bladder cancer cell growth arrest, apoptosis and chemosensitization through inhibition of STAT3 pathway. | 2015 | PLoS ONE | pmid:25849286 |
| Li XH et al. | Delta-tocotrienol suppresses radiation-induced microRNA-30 and protects mice and human CD34+ cells from radiation injury. | 2015 | PLoS ONE | pmid:25815474 |
| Hsu PY and Yang YW | Gene delivery via the hybrid vector of recombinant adeno-associated virus and polyethylenimine. | 2014 | Eur J Pharm Sci | pmid:24184196 |
| Lim SW et al. | Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells. | 2014 | BMC Complement Altern Med | pmid:25480449 |
| Ananthula S et al. | δ-Tocotrienol oxazine derivative antagonizes mammary tumor cell compensatory response to CoCl2-induced hypoxia. | 2014 | Biomed Res Int | pmid:25140303 |
| Haleagrahara N et al. | Therapeutic efficacy of vitamin E δ-tocotrienol in collagen-induced rat model of arthritis. | 2014 | Biomed Res Int | pmid:25114906 |
| Ananthula S et al. | Oxazine derivatives of γ- and δ-tocotrienol display enhanced anticancer activity in vivo. | 2014 | Anticancer Res. | pmid:24922632 |
| Singh VK et al. | Radioprotective efficacy of delta-tocotrienol, a vitamin E isoform, is mediated through granulocyte colony-stimulating factor. | 2014 | Life Sci. | pmid:24486300 |
| Viola V et al. | Mitochondrial-dependent anticancer activity of δ-tocotrienol and its synthetic derivatives in HER-2/neu overexpressing breast adenocarcinoma cells. | 2013 Jul-Aug | Biofactors | pmid:23361894 |
| Rodzian MN et al. | Pure tocotrienol concentrate protected rat gastric mucosa from acute stress-induced injury by a non-antioxidant mechanism. | 2013 | Pol J Pathol | pmid:23625601 |
| Behery FA et al. | Optimization of tocotrienols as antiproliferative and antimigratory leads. | 2013 | Eur J Med Chem | pmid:23274571 |
| Hodul PJ et al. | Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism. | 2013 | PLoS ONE | pmid:23393547 |
| Husain K et al. | Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E δ-tocotrienol. | 2013 | Carcinogenesis | pmid:23302291 |
| Li XH et al. | Delta-tocotrienol protects mice from radiation-induced gastrointestinal injury. | 2013 | Radiat. Res. | pmid:24294967 |
| Husain K et al. | Vitamin E δ-tocotrienol prolongs survival in the LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) transgenic mouse model of pancreatic cancer. | 2013 | Cancer Prev Res (Phila) | pmid:23963802 |
| Loganathan R et al. | Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity. | 2013 | Cell Prolif. | pmid:23510475 |
| Qureshi AA et al. | Nutritional Supplement-5 with a Combination of Proteasome Inhibitors (Resveratrol, Quercetin, δ-Tocotrienol) Modulate Age-Associated Biomarkers and Cardiovascular Lipid Parameters in Human Subjects. | 2013 | J Clin Exp Cardiolog | pmid:24319627 |
| Forster GM et al. | Rice varietal differences in bioactive bran components for inhibition of colorectal cancer cell growth. | 2013 | Food Chem | pmid:23790950 |
| Constantinou C et al. | Induction of DNA damage and caspase-independent programmed cell death by vitamin E. | 2012 | Nutr Cancer | pmid:22172208 |
| Wong RS et al. | δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells. | 2012 | Microsc. Microanal. | pmid:22640960 |
| Ji X et al. | Delta-tocotrienol augments cisplatin-induced suppression of non-small cell lung cancer cells via inhibition of the Notch-1 pathway. | 2012 | Anticancer Res. | pmid:22753722 |
| Satyamitra M et al. | Mechanism of radioprotection by δ-tocotrienol: pharmacokinetics, pharmacodynamics and modulation of signalling pathways. | 2012 | Br J Radiol | pmid:22674714 |
| Yue MA et al. | [Experimental study on delta-tocotrienol inhibits the Wnt pathway in the colon cancer cell SW620]. | 2012 | Wei Sheng Yan Jiu | pmid:23424864 |
| Ji X et al. | Delta-tocotrienol suppresses Notch-1 pathway by upregulating miR-34a in nonsmall cell lung cancer cells. | 2012 | Int. J. Cancer | pmid:22438124 |
| Krycer JR et al. | A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products. | 2012 | Biochem. J. | pmid:22657538 |
| Katuru R et al. | Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. | 2011 | Exp. Biol. Med. (Maywood) | pmid:21540247 |
| Tan SW et al. | Inhibitory effects of palm α-, γ- and δ-tocotrienol on lipopolysaccharide-induced nitric oxide production in BV2 microglia. | 2011 | Cell. Immunol. | pmid:21839427 |
| Satyamitra MM et al. | Hematopoietic Recovery and Amelioration of Radiation-Induced Lethality by the Vitamin E Isoform δ-Tocotrienol. | 2011 | Radiat. Res. | pmid:21434782 |
| Zhang JS et al. | A paraptosis-like cell death induced by δ-tocotrienol in human colon carcinoma SW620 cells is associated with the suppression of the Wnt signaling pathway. | 2011 | Toxicology | pmid:21453743 |
| Chen J et al. | Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cyclic GMP/protein kinase G signaling in cardiac fibroblasts. | 2011 | Circulation | pmid:21282499 |
| Ji X et al. | Inhibition of cell growth and induction of apoptosis in non-small cell lung cancer cells by delta-tocotrienol is associated with notch-1 down-regulation. | 2011 | J. Cell. Biochem. | pmid:21598300 |
| Qureshi AA et al. | Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by δ-tocotrienol and quercetin. | 2011 | Lipids Health Dis | pmid:22185406 |
| Husain K et al. | Vitamin E δ-tocotrienol augments the antitumor activity of gemcitabine and suppresses constitutive NF-κB activation in pancreatic cancer. | 2011 | Mol. Cancer Ther. | pmid:21971120 |
| Brooks R et al. | Direct inhibition of osteoclast formation and activity by the vitamin E isomer gamma-tocotrienol. | 2011 | Int J Vitam Nutr Res | pmid:22673919 |
| Qureshi AA et al. | δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens. | 2011 | Lipids Health Dis | pmid:21356098 |
| Pierpaoli E et al. | Gamma- and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression. | 2010 | Life Sci. | pmid:20188744 |
| Li F et al. | Tocotrienol enriched palm oil prevents atherosclerosis through modulating the activities of peroxisome proliferators-activated receptors. | 2010 | Atherosclerosis | pmid:20138624 |
| Zaiden N et al. | Gamma delta tocotrienols reduce hepatic triglyceride synthesis and VLDL secretion. | 2010 | J. Atheroscler. Thromb. | pmid:20702976 |
| Li XH et al. | Delta-tocotrienol protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling. | 2010 | Haematologica | pmid:20823133 |
| Michihara A et al. | Effect of δ-tocotrienol on melanin content and enzymes for melanin synthesis in mouse melanoma cells. | 2010 | Biol. Pharm. Bull. | pmid:20823559 |
| Mudit M et al. | Synthesis of fluorescent analogues of the anticancer natural products 4-hydroxyphenylmethylene hydantoin and delta-tocotrienol. | 2010 | Nat Prod Commun | pmid:21121261 |
| Fernandes NV et al. | d-δ-Tocotrienol-mediated cell cycle arrest and apoptosis in human melanoma cells. | 2010 | Anticancer Res. | pmid:21187473 |
| Yap WN et al. | Gamma- and delta-tocotrienols inhibit skin melanin synthesis by suppressing constitutive and UV-induced tyrosinase activation. | 2010 | Pigment Cell Melanoma Res | pmid:20609176 |
| Shibata A et al. | alpha-Tocopherol attenuates the cytotoxic effect of delta-tocotrienol in human colorectal adenocarcinoma cells. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20493172 |
| Hiura Y et al. | Specific accumulation of gamma- and delta-tocotrienols in tumor and their antitumor effect in vivo. | 2009 | J. Nutr. Biochem. | pmid:18824342 |
| Shibata A et al. | delta-Tocotrienol suppresses VEGF induced angiogenesis whereas alpha-tocopherol does not. | 2009 | J. Agric. Food Chem. | pmid:19702331 |
| Husain K et al. | Vitamin E delta-tocotrienol levels in tumor and pancreatic tissue of mice after oral administration. | 2009 | Pharmacology | pmid:19142032 |
| Constantinou C et al. | Induction of caspase-independent programmed cell death by vitamin E natural homologs and synthetic derivatives. | 2009 | Nutr Cancer | pmid:20155628 |
| Mazzini F et al. | Configuration of the vitamin E analogue garcinoic acid extracted from Garcinia Kola seeds. | 2009 | Chirality | pmid:18655162 |
| Elangovan S et al. | Growth inhibition of human MDA-mB-231 breast cancer cells by delta-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product. | 2008 Sep-Oct | Anticancer Res. | pmid:19035289 |
| Albermann C et al. | Biosynthesis of the vitamin E compound delta-tocotrienol in recombinant Escherichia coli cells. | 2008 | Chembiochem | pmid:18810749 |
| El Sayed KA et al. | Semisynthetic and biotransformation studies of (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol. | 2008 | J. Nat. Prod. | pmid:18177013 |
| Shibata A et al. | Tumor anti-angiogenic effect and mechanism of action of delta-tocotrienol. | 2008 | Biochem. Pharmacol. | pmid:18599020 |
| Couladouros EA et al. | A short and convenient chemical route to optically pure 2-methyl chromanmethanols. Total asymmetric synthesis of beta-, gamma-, and delta-tocotrienols. | 2007 | J. Org. Chem. | pmid:17685653 |
| Ung CY et al. | In silico prediction of pregnane X receptor activators by machine learning approaches. | 2007 | Mol. Pharmacol. | pmid:17003167 |
| Harinantenaina L et al. | Cinnamacrins A-C, cinnafragrin D, and cytostatic metabolites with alpha-glucosidase inhibitory activity from Cinnamosma macrocarpa. | 2007 | J. Nat. Prod. | pmid:17286431 |
| Sakai M et al. | Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells. | 2006 | J. Nutr. Biochem. | pmid:16517139 |
| Song BL and DeBose-Boyd RA | Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols. | 2006 | J. Biol. Chem. | pmid:16831864 |
| Yap SP and Yuen KH | Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations. | 2004 | Int J Pharm | pmid:15288344 |
| Zhou C et al. | Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. | 2004 | Drug Metab. Dispos. | pmid:15269186 |
| Shun MC et al. | Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells. | 2004 | Nutr Cancer | pmid:15203383 |
| Yap SP et al. | Influence of route of administration on the absorption and disposition of alpha-, gamma- and delta-tocotrienols in rats. | 2003 | J. Pharm. Pharmacol. | pmid:12625867 |
| Anderson SL et al. | Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12788105 |
| Seo EK et al. | Cytotoxic prenylated xanthones and the unusual compounds anthraquinobenzophenones from Cratoxylum sumatranum. | 2002 | J. Nat. Prod. | pmid:11908969 |
| Chao JT et al. | Inhibitory effect of delta-tocotrienol, a HMG CoA reductase inhibitor, on monocyte-endothelial cell adhesion. | 2002 | J. Nutr. Sci. Vitaminol. | pmid:12656204 |
| Sylvester PW et al. | Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation. | 2001 | Cell Prolif. | pmid:11736999 |
| Nakamura H et al. | Oral toxicity of a tocotrienol preparation in rats. | 2001 | Food Chem. Toxicol. | pmid:11434987 |
| Yap SP et al. | Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status. | 2001 | J. Pharm. Pharmacol. | pmid:11206194 |
| Black TM et al. | Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. | 2000 | J. Nutr. | pmid:11015467 |
| Yu W et al. | Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. | 1999 | Nutr Cancer | pmid:10227040 |
| Katsanidis E and Addis PB | Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue. | 1999 | Free Radic. Biol. Med. | pmid:10641704 |
| Guthrie N et al. | Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. | 1997 | J. Nutr. | pmid:9082043 |
| Kamat JP et al. | Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes. | 1997 | Mol. Cell. Biochem. | pmid:9144327 |
| Hayes KC et al. | Differences in the plasma transport and tissue concentrations of tocopherols and tocotrienols: observations in humans and hamsters. | 1993 | Proc. Soc. Exp. Biol. Med. | pmid:8437992 |
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