delta-tocotrienol

Delta-tocotrienol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 456 references associated with delta-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for delta-tocotrienol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with delta-tocotrienol

MeSH term MeSH ID Detail
Weight Gain D015430 101 associated lipids
Total 1

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with delta-tocotrienol

Download all related citations
Per page 10 20 50 100 | Total 104
Authors Title Published Journal PubMed Link
pmid:26286995
pmid:25093256
pmid:26593503
pmid:25662730
pmid:26523792
pmid:27884413
pmid:24680613
pmid:25534439
pmid:26446095
pmid:25355734
pmid:29491063
pmid:29141970
pmid:28825992
pmid:28786357
pmid:25285637
pmid:28404939
pmid:25225850
pmid:27713963
pmid:27461002
pmid:26947901
pmid:25979648
pmid:28362175
pmid:
Fernandes NV et al. d-δ-Tocotrienol-mediated cell cycle arrest and apoptosis in human melanoma cells. 2010 Anticancer Res. pmid:21187473
Elangovan S et al. Growth inhibition of human MDA-mB-231 breast cancer cells by delta-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product. 2008 Sep-Oct Anticancer Res. pmid:19035289
Ji X et al. Delta-tocotrienol augments cisplatin-induced suppression of non-small cell lung cancer cells via inhibition of the Notch-1 pathway. 2012 Anticancer Res. pmid:22753722
Ananthula S et al. Oxazine derivatives of γ- and δ-tocotrienol display enhanced anticancer activity in vivo. 2014 Anticancer Res. pmid:24922632
Li F et al. Tocotrienol enriched palm oil prevents atherosclerosis through modulating the activities of peroxisome proliferators-activated receptors. 2010 Atherosclerosis pmid:20138624
Anderson SL et al. Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia. 2003 Biochem. Biophys. Res. Commun. pmid:12788105
Shibata A et al. alpha-Tocopherol attenuates the cytotoxic effect of delta-tocotrienol in human colorectal adenocarcinoma cells. 2010 Biochem. Biophys. Res. Commun. pmid:20493172
Krycer JR et al. A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products. 2012 Biochem. J. pmid:22657538
Shibata A et al. Tumor anti-angiogenic effect and mechanism of action of delta-tocotrienol. 2008 Biochem. Pharmacol. pmid:18599020
Viola V et al. Mitochondrial-dependent anticancer activity of δ-tocotrienol and its synthetic derivatives in HER-2/neu overexpressing breast adenocarcinoma cells. 2013 Jul-Aug Biofactors pmid:23361894
Michihara A et al. Effect of δ-tocotrienol on melanin content and enzymes for melanin synthesis in mouse melanoma cells. 2010 Biol. Pharm. Bull. pmid:20823559
Ananthula S et al. δ-Tocotrienol oxazine derivative antagonizes mammary tumor cell compensatory response to CoCl2-induced hypoxia. 2014 Biomed Res Int pmid:25140303
Haleagrahara N et al. Therapeutic efficacy of vitamin E δ-tocotrienol in collagen-induced rat model of arthritis. 2014 Biomed Res Int pmid:25114906
Lim SW et al. Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells. 2014 BMC Complement Altern Med pmid:25480449
Satyamitra M et al. Mechanism of radioprotection by δ-tocotrienol: pharmacokinetics, pharmacodynamics and modulation of signalling pathways. 2012 Br J Radiol pmid:22674714
Mahipal A et al. Pharmacokinetics and safety of vitamin E δ-tocotrienol after single and multiple doses in healthy subjects with measurement of vitamin E metabolites. 2016 Cancer Chemother. Pharmacol. pmid:27278668
Husain K et al. Vitamin E δ-tocotrienol prolongs survival in the LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) transgenic mouse model of pancreatic cancer. 2013 Cancer Prev Res (Phila) pmid:23963802
Husain K et al. Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E δ-tocotrienol. 2013 Carcinogenesis pmid:23302291
Sylvester PW et al. Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation. 2001 Cell Prolif. pmid:11736999
Loganathan R et al. Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity. 2013 Cell Prolif. pmid:23510475
Tan SW et al. Inhibitory effects of palm α-, γ- and δ-tocotrienol on lipopolysaccharide-induced nitric oxide production in BV2 microglia. 2011 Cell. Immunol. pmid:21839427
Albermann C et al. Biosynthesis of the vitamin E compound delta-tocotrienol in recombinant Escherichia coli cells. 2008 Chembiochem pmid:18810749
Mazzini F et al. Configuration of the vitamin E analogue garcinoic acid extracted from Garcinia Kola seeds. 2009 Chirality pmid:18655162
Chen J et al. Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cyclic GMP/protein kinase G signaling in cardiac fibroblasts. 2011 Circulation pmid:21282499
Zhou C et al. Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. 2004 Drug Metab. Dispos. pmid:15269186
Springett GM et al. A Phase I Safety, Pharmacokinetic, and Pharmacodynamic Presurgical Trial of Vitamin E δ-tocotrienol in Patients with Pancreatic Ductal Neoplasia. 2015 EBioMedicine pmid:26844278
Behery FA et al. Optimization of tocotrienols as antiproliferative and antimigratory leads. 2013 Eur J Med Chem pmid:23274571