delta-tocotrienol

Delta-tocotrienol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 456 references associated with delta-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for delta-tocotrienol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with delta-tocotrienol

MeSH term MeSH ID Detail
Weight Gain D015430 101 associated lipids
Total 1

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with delta-tocotrienol

Download all related citations
Per page 10 20 50 100 | Total 104
Authors Title Published Journal PubMed Link
pmid:
Yu W et al. Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. 1999 Nutr Cancer pmid:10227040
Katsanidis E and Addis PB Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue. 1999 Free Radic. Biol. Med. pmid:10641704
Black TM et al. Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. 2000 J. Nutr. pmid:11015467
Yap SP et al. Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status. 2001 J. Pharm. Pharmacol. pmid:11206194
Nakamura H et al. Oral toxicity of a tocotrienol preparation in rats. 2001 Food Chem. Toxicol. pmid:11434987
Sylvester PW et al. Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation. 2001 Cell Prolif. pmid:11736999
Seo EK et al. Cytotoxic prenylated xanthones and the unusual compounds anthraquinobenzophenones from Cratoxylum sumatranum. 2002 J. Nat. Prod. pmid:11908969
Yap SP et al. Influence of route of administration on the absorption and disposition of alpha-, gamma- and delta-tocotrienols in rats. 2003 J. Pharm. Pharmacol. pmid:12625867
Chao JT et al. Inhibitory effect of delta-tocotrienol, a HMG CoA reductase inhibitor, on monocyte-endothelial cell adhesion. 2002 J. Nutr. Sci. Vitaminol. pmid:12656204
Anderson SL et al. Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia. 2003 Biochem. Biophys. Res. Commun. pmid:12788105
Shun MC et al. Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells. 2004 Nutr Cancer pmid:15203383
Zhou C et al. Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. 2004 Drug Metab. Dispos. pmid:15269186
Yap SP and Yuen KH Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations. 2004 Int J Pharm pmid:15288344
Sakai M et al. Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells. 2006 J. Nutr. Biochem. pmid:16517139
Song BL and DeBose-Boyd RA Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols. 2006 J. Biol. Chem. pmid:16831864
Ung CY et al. In silico prediction of pregnane X receptor activators by machine learning approaches. 2007 Mol. Pharmacol. pmid:17003167
Harinantenaina L et al. Cinnamacrins A-C, cinnafragrin D, and cytostatic metabolites with alpha-glucosidase inhibitory activity from Cinnamosma macrocarpa. 2007 J. Nat. Prod. pmid:17286431
Couladouros EA et al. A short and convenient chemical route to optically pure 2-methyl chromanmethanols. Total asymmetric synthesis of beta-, gamma-, and delta-tocotrienols. 2007 J. Org. Chem. pmid:17685653
El Sayed KA et al. Semisynthetic and biotransformation studies of (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol. 2008 J. Nat. Prod. pmid:18177013
Shibata A et al. Tumor anti-angiogenic effect and mechanism of action of delta-tocotrienol. 2008 Biochem. Pharmacol. pmid:18599020
Mazzini F et al. Configuration of the vitamin E analogue garcinoic acid extracted from Garcinia Kola seeds. 2009 Chirality pmid:18655162
Albermann C et al. Biosynthesis of the vitamin E compound delta-tocotrienol in recombinant Escherichia coli cells. 2008 Chembiochem pmid:18810749
Hiura Y et al. Specific accumulation of gamma- and delta-tocotrienols in tumor and their antitumor effect in vivo. 2009 J. Nutr. Biochem. pmid:18824342
Elangovan S et al. Growth inhibition of human MDA-mB-231 breast cancer cells by delta-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product. 2008 Sep-Oct Anticancer Res. pmid:19035289
Husain K et al. Vitamin E delta-tocotrienol levels in tumor and pancreatic tissue of mice after oral administration. 2009 Pharmacology pmid:19142032
Shibata A et al. delta-Tocotrienol suppresses VEGF induced angiogenesis whereas alpha-tocopherol does not. 2009 J. Agric. Food Chem. pmid:19702331
Li F et al. Tocotrienol enriched palm oil prevents atherosclerosis through modulating the activities of peroxisome proliferators-activated receptors. 2010 Atherosclerosis pmid:20138624
Constantinou C et al. Induction of caspase-independent programmed cell death by vitamin E natural homologs and synthetic derivatives. 2009 Nutr Cancer pmid:20155628
Pierpaoli E et al. Gamma- and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression. 2010 Life Sci. pmid:20188744
Shibata A et al. alpha-Tocopherol attenuates the cytotoxic effect of delta-tocotrienol in human colorectal adenocarcinoma cells. 2010 Biochem. Biophys. Res. Commun. pmid:20493172
Yap WN et al. Gamma- and delta-tocotrienols inhibit skin melanin synthesis by suppressing constitutive and UV-induced tyrosinase activation. 2010 Pigment Cell Melanoma Res pmid:20609176
Zaiden N et al. Gamma delta tocotrienols reduce hepatic triglyceride synthesis and VLDL secretion. 2010 J. Atheroscler. Thromb. pmid:20702976
Li XH et al. Delta-tocotrienol protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling. 2010 Haematologica pmid:20823133
Michihara A et al. Effect of δ-tocotrienol on melanin content and enzymes for melanin synthesis in mouse melanoma cells. 2010 Biol. Pharm. Bull. pmid:20823559
Mudit M et al. Synthesis of fluorescent analogues of the anticancer natural products 4-hydroxyphenylmethylene hydantoin and delta-tocotrienol. 2010 Nat Prod Commun pmid:21121261
Fernandes NV et al. d-δ-Tocotrienol-mediated cell cycle arrest and apoptosis in human melanoma cells. 2010 Anticancer Res. pmid:21187473
Chen J et al. Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cyclic GMP/protein kinase G signaling in cardiac fibroblasts. 2011 Circulation pmid:21282499
Qureshi AA et al. δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens. 2011 Lipids Health Dis pmid:21356098
Satyamitra MM et al. Hematopoietic Recovery and Amelioration of Radiation-Induced Lethality by the Vitamin E Isoform δ-Tocotrienol. 2011 Radiat. Res. pmid:21434782
Zhang JS et al. A paraptosis-like cell death induced by δ-tocotrienol in human colon carcinoma SW620 cells is associated with the suppression of the Wnt signaling pathway. 2011 Toxicology pmid:21453743
Katuru R et al. Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. 2011 Exp. Biol. Med. (Maywood) pmid:21540247
Ji X et al. Inhibition of cell growth and induction of apoptosis in non-small cell lung cancer cells by delta-tocotrienol is associated with notch-1 down-regulation. 2011 J. Cell. Biochem. pmid:21598300
Tan SW et al. Inhibitory effects of palm α-, γ- and δ-tocotrienol on lipopolysaccharide-induced nitric oxide production in BV2 microglia. 2011 Cell. Immunol. pmid:21839427
Husain K et al. Vitamin E δ-tocotrienol augments the antitumor activity of gemcitabine and suppresses constitutive NF-κB activation in pancreatic cancer. 2011 Mol. Cancer Ther. pmid:21971120
Constantinou C et al. Induction of DNA damage and caspase-independent programmed cell death by vitamin E. 2012 Nutr Cancer pmid:22172208
Qureshi AA et al. Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by δ-tocotrienol and quercetin. 2011 Lipids Health Dis pmid:22185406
Ji X et al. Delta-tocotrienol suppresses Notch-1 pathway by upregulating miR-34a in nonsmall cell lung cancer cells. 2012 Int. J. Cancer pmid:22438124
Wong RS et al. δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells. 2012 Microsc. Microanal. pmid:22640960
Krycer JR et al. A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products. 2012 Biochem. J. pmid:22657538