| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
Total
1
gamma-tocotrienol
Gamma-tocotrienol is a lipid of Prenol Lipids (PR) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 1076 references associated with gamma-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for gamma-tocotrienol
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-tocotrienol
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with gamma-tocotrienol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Theriault A et al. | Effects of gamma-tocotrienol on ApoB synthesis, degradation, and secretion in HepG2 cells. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:10073977 |
| Mo H and Elson CE | Apoptosis and cell-cycle arrest in human and murine tumor cells are initiated by isoprenoids. | 1999 | J. Nutr. | pmid:10203554 |
| Yu W et al. | Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. | 1999 | Nutr Cancer | pmid:10227040 |
| Newaz MA and Nawal NN | Effect of gamma-tocotrienol on blood pressure, lipid peroxidation and total antioxidant status in spontaneously hypertensive rats (SHR). | 1999 | Clin. Exp. Hypertens. | pmid:10574414 |
| Katsanidis E and Addis PB | Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue. | 1999 | Free Radic. Biol. Med. | pmid:10641704 |
| Sen CK et al. | Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells. | 2000 | J. Biol. Chem. | pmid:10777609 |
| Goffman FD and Möllers C | Changes in tocopherol and plastochromanol-8 contents in seeds and oil of oilseed rape (Brassica napus L.) during storage as influenced by temperature and air oxygen. | 2000 | J. Agric. Food Chem. | pmid:10820066 |
| Black TM et al. | Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. | 2000 | J. Nutr. | pmid:11015467 |
| Hattori A et al. | Production of LLU-alpha following an oral administration of gamma-tocotrienol or gamma-tocopherol to rats. | 2000 | Biol. Pharm. Bull. | pmid:11085376 |
| Qureshi AA et al. | Novel tocotrienols of rice bran suppress cholesterogenesis in hereditary hypercholesterolemic swine. | 2001 | J. Nutr. | pmid:11160537 |
| Yap SP et al. | Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status. | 2001 | J. Pharm. Pharmacol. | pmid:11206194 |
| Nakamura H et al. | Oral toxicity of a tocotrienol preparation in rats. | 2001 | Food Chem. Toxicol. | pmid:11434987 |
| Ikeda S et al. | Dietary sesame seeds elevate alpha- and gamma-tocotrienol concentrations in skin and adipose tissue of rats fed the tocotrienol-rich fraction extracted from palm oil. | 2001 | J. Nutr. | pmid:11694614 |
| Sylvester PW et al. | Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation. | 2001 | Cell Prolif. | pmid:11736999 |
| Raederstorff D et al. | Effect of either gamma-tocotrienol or a tocotrienol mixture on the plasma lipid profile in hamsters. | 2002 | Ann. Nutr. Metab. | pmid:11914511 |
| Mustad VA et al. | Supplementation with 3 compositionally different tocotrienol supplements does not improve cardiovascular disease risk factors in men and women with hypercholesterolemia. | 2002 | Am. J. Clin. Nutr. | pmid:12450888 |
| Fuchs J et al. | HPLC analysis of vitamin E isoforms in human epidermis: correlation with minimal erythema dose and free radical scavenging activity. | 2003 | Free Radic. Biol. Med. | pmid:12543248 |
| Ikeda S et al. | Dietary alpha-tocopherol decreases alpha-tocotrienol but not gamma-tocotrienol concentration in rats. | 2003 | J. Nutr. | pmid:12566479 |
| Yap SP et al. | Influence of route of administration on the absorption and disposition of alpha-, gamma- and delta-tocotrienols in rats. | 2003 | J. Pharm. Pharmacol. | pmid:12625867 |
| Saito H et al. | Gamma-tocotrienol, a vitamin E homolog, is a natriuretic hormone precursor. | 2003 | J. Lipid Res. | pmid:12730299 |
| Newaz MA et al. | Nitric oxide synthase activity in blood vessels of spontaneously hypertensive rats: antioxidant protection by gamma-tocotrienol. | 2003 | J. Physiol. Pharmacol. | pmid:14566071 |
| Zhou C et al. | Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. | 2004 | Drug Metab. Dispos. | pmid:15269186 |
| Yap SP and Yuen KH | Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations. | 2004 | Int J Pharm | pmid:15288344 |
| Shah SJ and Sylvester PW | Tocotrienol-induced cytotoxicity is unrelated to mitochondrial stress apoptotic signaling in neoplastic mammary epithelial cells. | 2005 | Biochem. Cell Biol. | pmid:15746970 |
| Conte C et al. | Gamma-tocotrienol metabolism and antiproliferative effect in prostate cancer cells. | 2004 | Ann. N. Y. Acad. Sci. | pmid:15753178 |
| Shah SJ and Sylvester PW | Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity. | 2005 | Exp. Biol. Med. (Maywood) | pmid:15792944 |
| Sylvester PW et al. | Intracellular signaling mechanisms mediating the antiproliferative and apoptotic effects of gamma-tocotrienol in neoplastic mammary epithelial cells. | 2005 | J. Plant Physiol. | pmid:16008108 |
| Kumar KS et al. | Preferential radiation sensitization of prostate cancer in nude mice by nutraceutical antioxidant gamma-tocotrienol. | 2006 | Life Sci. | pmid:16413038 |
| Mazlan M et al. | Comparative effects of alpha-tocopherol and gamma-tocotrienol against hydrogen peroxide induced apoptosis on primary-cultured astrocytes. | 2006 | J. Neurol. Sci. | pmid:16442562 |
| Sakai M et al. | Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells. | 2006 | J. Nutr. Biochem. | pmid:16517139 |
| Song BL and DeBose-Boyd RA | Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols. | 2006 | J. Biol. Chem. | pmid:16831864 |
| Ung CY et al. | In silico prediction of pregnane X receptor activators by machine learning approaches. | 2007 | Mol. Pharmacol. | pmid:17003167 |
| Samant GV and Sylvester PW | gamma-Tocotrienol inhibits ErbB3-dependent PI3K/Akt mitogenic signalling in neoplastic mammary epithelial cells. | 2006 | Cell Prolif. | pmid:17109639 |
| Ahn KS et al. | Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis. | 2007 | J. Biol. Chem. | pmid:17114179 |
| Abe C et al. | Triton WR1339, an inhibitor of lipoprotein lipase, decreases vitamin E concentration in some tissues of rats by inhibiting its transport to liver. | 2007 | J. Nutr. | pmid:17237309 |
| Kawakami Y et al. | Distribution of tocotrienols in rats fed a rice bran tocotrienol concentrate. | 2007 | Biosci. Biotechnol. Biochem. | pmid:17284857 |
| Tsuzuki W et al. | Intestinal epithelial cells absorb gamma-tocotrienol faster than alpha-tocopherol. | 2007 | Lipids | pmid:17393222 |
| Akaho N et al. | Preparation and in vivo evaluation of a water-soluble prodrug for 2R-gamma-tocotrienol and as a two-step prodrug for 2,7,8-trimethyl-2S-(beta-carboxyethyl)-6-hydroxychroman (S-gamma-CEHC) in rat. | 2007 | Drug Metab. Dispos. | pmid:17537874 |
| Couladouros EA et al. | A short and convenient chemical route to optically pure 2-methyl chromanmethanols. Total asymmetric synthesis of beta-, gamma-, and delta-tocotrienols. | 2007 | J. Org. Chem. | pmid:17685653 |
| Wali VB and Sylvester PW | Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells. | 2007 | Lipids | pmid:17701065 |
| Szymańska R and Kruk J | [Occurrence and function of tocochromanols in plants, animals and men]. | 2007 | Postepy Biochem. | pmid:17969879 |
| Sun W et al. | Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling. | 2008 | Br. J. Nutr. | pmid:18081943 |
| Sun W et al. | gamma-Tocotrienol induces mitochondria-mediated apoptosis in human gastric adenocarcinoma SGC-7901 cells. | 2009 | J. Nutr. Biochem. | pmid:18602811 |
| Hsieh TC and Wu JM | Suppression of cell proliferation and gene expression by combinatorial synergy of EGCG, resveratrol and gamma-tocotrienol in estrogen receptor-positive MCF-7 breast cancer cells. | 2008 | Int. J. Oncol. | pmid:18813800 |
| Hiura Y et al. | Specific accumulation of gamma- and delta-tocotrienols in tumor and their antitumor effect in vivo. | 2009 | J. Nutr. Biochem. | pmid:18824342 |
| Yap WN et al. | Gamma-tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways. | 2008 | Br. J. Cancer | pmid:19002171 |
| Hermizi H et al. | Beneficial effects of tocotrienol and tocopherol on bone histomorphometric parameters in sprague-dawley male rats after nicotine cessation. | 2009 | Calcif. Tissue Int. | pmid:19020790 |
| Jiang Q et al. | Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19074288 |
| Nikolic K and Agababa D | Design and QSAR study of analogs of gamma-tocotrienol with enhanced antiproliferative activity against human breast cancer cells. | 2009 | J. Mol. Graph. Model. | pmid:19117779 |