gamma-tocotrienol

Gamma-tocotrienol is a lipid of Prenol Lipids (PR) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 1076 references associated with gamma-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for gamma-tocotrienol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-tocotrienol

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Total 1

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with gamma-tocotrienol

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Authors Title Published Journal PubMed Link
Guthrie N et al. Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. 1997 J. Nutr. pmid:9082043
Qureshi AA et al. Dietary alpha-tocopherol attenuates the impact of gamma-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickens. 1996 J. Nutr. pmid:8632210
Freiser H and Jiang Q Gamma-tocotrienol and gamma-tocopherol are primarily metabolized to conjugated 2-(beta-carboxyethyl)-6-hydroxy-2,7,8-trimethylchroman and sulfated long-chain carboxychromanols in rats. 2009 J. Nutr. pmid:19297424
Mazlan M et al. Comparative effects of alpha-tocopherol and gamma-tocotrienol against hydrogen peroxide induced apoptosis on primary-cultured astrocytes. 2006 J. Neurol. Sci. pmid:16442562
Nikolic K and Agababa D Design and QSAR study of analogs of gamma-tocotrienol with enhanced antiproliferative activity against human breast cancer cells. 2009 J. Mol. Graph. Model. pmid:19117779
Kim Y et al. Suppression of NLRP3 inflammasome by γ-tocotrienol ameliorates type 2 diabetes. 2016 J. Lipid Res. pmid:26628639
Saito H et al. Gamma-tocotrienol, a vitamin E homolog, is a natriuretic hormone precursor. 2003 J. Lipid Res. pmid:12730299
Mangialasche F et al. Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol. 2013 J. Intern. Med. pmid:23343471
Peh HY et al. Vitamin E Isoform γ-Tocotrienol Downregulates House Dust Mite-Induced Asthma. 2015 J. Immunol. pmid:26041537
Mao Y et al. Chemical Composition Analysis, Sensory, and Feasibility Study of Tree Peony Seed. 2017 J. Food Sci. pmid:28135396
Mukhopadhyay P et al. Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. 2012 J. Cell. Mol. Med. pmid:22050707
Lekli I et al. Co-ordinated autophagy with resveratrol and γ-tocotrienol confers synergetic cardioprotection. 2010 J. Cell. Mol. Med. pmid:19799646
Shuid AN et al. Vitamin E exhibits bone anabolic actions in normal male rats. 2010 J. Bone Miner. Metab. pmid:19779668
Ahn KS et al. Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis. 2007 J. Biol. Chem. pmid:17114179
Block A et al. Functional modeling identifies paralogous solanesyl-diphosphate synthases that assemble the side chain of plastoquinone-9 in plastids. 2013 J. Biol. Chem. pmid:23913686
Strenkert D et al. Genetically Programmed Changes in Photosynthetic Cofactor Metabolism in Copper-deficient Chlamydomonas. 2016 J. Biol. Chem. pmid:27440043
Song BL and DeBose-Boyd RA Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols. 2006 J. Biol. Chem. pmid:16831864
Parker RA et al. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. 1993 J. Biol. Chem. pmid:8388388
Sen CK et al. Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells. 2000 J. Biol. Chem. pmid:10777609
Kannappan R et al. γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents. 2010 J. Biol. Chem. pmid:20720018