| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
Total
1
gamma-tocotrienol
Gamma-tocotrienol is a lipid of Prenol Lipids (PR) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 1076 references associated with gamma-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for gamma-tocotrienol
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-tocotrienol
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with gamma-tocotrienol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang Q et al. | Effects of tocotrienol on the intracellular translocation and degradation of apolipoprotein B: possible involvement of a proteasome independent pathway. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9618265 |
| He L et al. | Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo. | 1997 | J. Nutr. | pmid:9164984 |
| Makpol S et al. | Different starting times of alpha-tocopherol and gamma-tocotrienol supplementation and tumor marker enzyme activities in the rat chemically induced with cancer. | 1997 | Gen. Pharmacol. | pmid:9147029 |
| Kamat JP et al. | Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes. | 1997 | Mol. Cell. Biochem. | pmid:9144327 |
| Guthrie N et al. | Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. | 1997 | J. Nutr. | pmid:9082043 |
| Qureshi AA et al. | Dietary alpha-tocopherol attenuates the impact of gamma-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickens. | 1996 | J. Nutr. | pmid:8632210 |
| Tomeo AC et al. | Antioxidant effects of tocotrienols in patients with hyperlipidemia and carotid stenosis. | 1995 | Lipids | pmid:8614310 |
| Qureshi AA et al. | Response of hypercholesterolemic subjects to administration of tocotrienols. | 1995 | Lipids | pmid:8614309 |
| Suarna C et al. | Comparative antioxidant activity of tocotrienols and other natural lipid-soluble antioxidants in a homogeneous system, and in rat and human lipoproteins. | 1993 | Biochim. Biophys. Acta | pmid:8443232 |
| Parker RA et al. | Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 1993 | J. Biol. Chem. | pmid:8388388 |
| Watkins T et al. | gamma-Tocotrienol as a hypocholesterolemic and antioxidant agent in rats fed atherogenic diets. | 1993 | Lipids | pmid:8121254 |
| Ong FB et al. | Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol. | 1993 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:7903615 |
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| Jang Y et al. | Gamma-tocotrienol profoundly alters sphingolipids in cancer cells by inhibition of dihydroceramide desaturase and possibly activation of sphingolipid hydrolysis during prolonged treatment. | 2017 | J. Nutr. Biochem. | pmid:28456081 |
| Mao Y et al. | Chemical Composition Analysis, Sensory, and Feasibility Study of Tree Peony Seed. | 2017 | J. Food Sci. | pmid:28135396 |
| pmid:28119116 | ||||
| Ledet GA et al. | Development of Orally Administered γ-Tocotrienol (GT3) Nanoemulsion for Radioprotection. | 2016 | Int J Mol Sci | pmid:28029115 |
| Algayadh IG et al. | Role of Rac1/WAVE2 Signaling in Mediating the Inhibitory Effects of γ-Tocotrienol on Mammary Cancer Cell Migration and Invasion. | 2016 | Biol. Pharm. Bull. | pmid:27904039 |
| Pathak R et al. | The Vitamin E Analog Gamma-Tocotrienol (GT3) and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM). | 2016 | Int J Mol Sci | pmid:27869747 |
| Ding Y et al. | Gamma-tocotrienol reverses multidrug resistance of breast cancer cells with a mechanism distinct from that of atorvastatin. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:27864002 |
| pmid:27855904 | ||||
| pmid:27743340 | ||||
| pmid:27714977 | ||||
| pmid:27713963 | ||||
| Prasad S et al. | γ-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules. | 2016 | Br. J. Cancer | pmid:27575851 |
| pmid:27542813 | ||||
| Dłużewska J et al. | Tocopherol Cyclases-Substrate Specificity and Phylogenetic Relations. | 2016 | PLoS ONE | pmid:27462710 |
| Strenkert D et al. | Genetically Programmed Changes in Photosynthetic Cofactor Metabolism in Copper-deficient Chlamydomonas. | 2016 | J. Biol. Chem. | pmid:27440043 |
| Singh VK et al. | Progenitor Cell Mobilization by Gamma-tocotrienol: A Promising Radiation Countermeasure. | 2016 | Health Phys | pmid:27356050 |
| pmid:27323693 | ||||
| Singh VK and Hauer-Jensen M | γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. | 2016 | Int J Mol Sci | pmid:27153057 |
| pmid:27133421 | ||||
| Yamashita S et al. | γ-Tocotrienol upregulates aryl hydrocarbon receptor expression and enhances the anticancer effect of baicalein. | 2016 | Biochem. Biophys. Res. Commun. | pmid:27055589 |
| pmid:27008382 | ||||
| Zhao L et al. | Regulation of Obesity and Metabolic Complications by Gamma and Delta Tocotrienols. | 2016 | Molecules | pmid:26978344 |
| pmid:26930378 | ||||
| Kim Y et al. | Suppression of NLRP3 inflammasome by γ-tocotrienol ameliorates type 2 diabetes. | 2016 | J. Lipid Res. | pmid:26628639 |
| pmid:26593503 | ||||
| pmid:26507543 | ||||
| pmid:26471549 | ||||
| Kim EH et al. | Fibrillin 5 Is Essential for Plastoquinone-9 Biosynthesis by Binding to Solanesyl Diphosphate Synthases in Arabidopsis. | 2015 | Plant Cell | pmid:26432861 |
| Parajuli P et al. | Anticancer Effects of γ-Tocotrienol Are Associated with a Suppression in Aerobic Glycolysis. | 2015 | Biol. Pharm. Bull. | pmid:26328490 |
| Meganathan P et al. | A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to existing Tocotrienol-Rich Fraction in healthy human subjects. | 2015 | Sci Rep | pmid:26323969 |
| Gu W et al. | Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway. | 2015 | BMC Cancer | pmid:26315028 |
| pmid:26286995 | ||||
| pmid:26208883 | ||||
| pmid:26112904 | ||||
| pmid:26096843 | ||||
| Yusof KM et al. | γ-Tocotrienol and 6-Gingerol in Combination Synergistically Induce Cytotoxicity and Apoptosis in HT-29 and SW837 Human Colorectal Cancer Cells. | 2015 | Molecules | pmid:26046324 |
| Peh HY et al. | Vitamin E Isoform γ-Tocotrienol Downregulates House Dust Mite-Induced Asthma. | 2015 | J. Immunol. | pmid:26041537 |
| pmid:26021733 | ||||
| pmid:25956071 | ||||
| Zhifang M et al. | The androgen receptor plays a suppressive role in epithelial- mesenchymal transition of human prostate cancer stem progenitor cells. | 2015 | BMC Biochem. | pmid:25943311 |
| Abdul Rahman Sazli F et al. | Gamma-tocotrienol treatment increased peroxiredoxin-4 expression in HepG2 liver cancer cell line. | 2015 | BMC Complement Altern Med | pmid:25886747 |
| pmid:25844964 | ||||
| pmid:25648304 | ||||
| pmid:25622049 | ||||
| Lim SW et al. | Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells. | 2014 | BMC Complement Altern Med | pmid:25480449 |
| Singh VK et al. | Progenitors mobilized by gamma-tocotrienol as an effective radiation countermeasure. | 2014 | PLoS ONE | pmid:25423021 |
| pmid:25355734 | ||||
| pmid:25308762 | ||||
| Liu J et al. | Polysaccharopeptide enhanced the anti-cancer effect of gamma-tocotrienol through activation of AMPK. | 2014 | BMC Complement Altern Med | pmid:25129068 |
| pmid:25105230 | ||||
| pmid:25093256 | ||||
| pmid:25042861 | ||||
| pmid:25019595 | ||||
| Abdul Rahman A et al. | Gamma-tocotrienol and hydroxy-chavicol synergistically inhibits growth and induces apoptosis of human glioma cells. | 2014 | BMC Complement Altern Med | pmid:24980711 |
| Pintha K et al. | Anti-invasive activity against cancer cells of phytochemicals in red jasmine rice (Oryza sativa L.). | 2014 | Asian Pac. J. Cancer Prev. | pmid:24969892 |
| pmid:24934591 | ||||
| Ananthula S et al. | Oxazine derivatives of γ- and δ-tocotrienol display enhanced anticancer activity in vivo. | 2014 | Anticancer Res. | pmid:24922632 |
| Siveen KS et al. | Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model. | 2014 | Oncotarget | pmid:24722367 |
| Deng L et al. | Tissue distribution of emulsified γ-tocotrienol and its long-term biological effects after subcutaneous administration. | 2014 | Lipids Health Dis | pmid:24712339 |
| pmid:24668775 | ||||
| Tiwari RV et al. | γ-Tocotrienol-induced autophagy in malignant mammary cancer cells. | 2014 | Exp. Biol. Med. (Maywood) | pmid:24231340 |
| Ayoub NM et al. | Combined γ-tocotrienol and Met inhibitor treatment suppresses mammary cancer cell proliferation, epithelial-to-mesenchymal transition and migration. | 2013 | Cell Prolif. | pmid:24033536 |
| Suman S et al. | Gamma tocotrienol, a potent radioprotector, preferentially upregulates expression of anti-apoptotic genes to promote intestinal cell survival. | 2013 | Food Chem. Toxicol. | pmid:23941772 |
| Block A et al. | Functional modeling identifies paralogous solanesyl-diphosphate synthases that assemble the side chain of plastoquinone-9 in plastids. | 2013 | J. Biol. Chem. | pmid:23913686 |
| Tuerdi G et al. | Synergistic effect of combined treatment with gamma-tocotrienol and statin on human malignant mesothelioma cells. | 2013 | Cancer Lett. | pmid:23879968 |
| Wu SJ et al. | γ-Tocotrienol induced cell cycle arrest and apoptosis via activating the Bax-mediated mitochondrial and AMPK signaling pathways in 3T3-L1 adipocytes. | 2013 | Food Chem. Toxicol. | pmid:23816832 |
| Burdeos GC et al. | γ-Tocotrienol attenuates triglyceride through effect on lipogenic gene expressions in mouse hepatocellular carcinoma Hepa 1-6. | 2013 | J. Nutr. Sci. Vitaminol. | pmid:23727646 |
| Szymańska R | [Chloroplast prenylated lipids in response to stress in plants]. | 2012 | Postepy Biochem. | pmid:23662431 |
| Makpol S et al. | Gamma-tocotrienol modulated gene expression in senescent human diploid fibroblasts as revealed by microarray analysis. | 2013 | Oxid Med Cell Longev | pmid:23634235 |
| Martinis J et al. | A chloroplast ABC1-like kinase regulates vitamin E metabolism in Arabidopsis. | 2013 | Plant Physiol. | pmid:23632854 |
| Rodzian MN et al. | Pure tocotrienol concentrate protected rat gastric mucosa from acute stress-induced injury by a non-antioxidant mechanism. | 2013 | Pol J Pathol | pmid:23625601 |
| Kulkarni S et al. | Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure. | 2013 | Cytokine | pmid:23561424 |
| Loganathan R et al. | Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity. | 2013 | Cell Prolif. | pmid:23510475 |
| Zhang JS et al. | γ-Tocotrienol induces paraptosis-like cell death in human colon carcinoma SW620 cells. | 2013 | PLoS ONE | pmid:23469066 |
| Kamsani YS et al. | Nicotine-induced cessation of embryonic development is reversed by γ-tocotrienol in mice. | 2013 | Med Sci Monit Basic Res | pmid:23462735 |
| Ray S et al. | Mobilization of progenitor cells into peripheral blood by gamma-tocotrienol: a promising radiation countermeasure. | 2013 | Int. Immunopharmacol. | pmid:23415908 |
| Mangialasche F et al. | Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol. | 2013 | J. Intern. Med. | pmid:23343471 |
| Akl MR et al. | Sesamin synergistically potentiates the anticancer effects of γ-tocotrienol in mammary cancer cell lines. | 2013 | Fitoterapia | pmid:23266736 |
| Wang Y and Jiang Q | γ-Tocotrienol inhibits lipopolysaccharide-induced interlukin-6 and granulocyte colony-stimulating factor by suppressing C/EBPβ and NF-κB in macrophages. | 2013 | J. Nutr. Biochem. | pmid:23246159 |
| Kani K et al. | γ-tocotrienol enhances the chemosensitivity of human oral cancer cells to docetaxel through the downregulation of the expression of NF-κB-regulated anti-apoptotic gene products. | 2013 | Int. J. Oncol. | pmid:23138939 |
| Gopalan A et al. | Involvement of de novo ceramide synthesis in gamma-tocopherol and gamma-tocotrienol-induced apoptosis in human breast cancer cells. | 2012 | Mol Nutr Food Res | pmid:23065795 |
| Gopalan A et al. | Eliminating drug resistant breast cancer stem-like cells with combination of simvastatin and gamma-tocotrienol. | 2013 | Cancer Lett. | pmid:23063651 |
| Kulkarni SS et al. | Gamma-tocotrienol, a radiation prophylaxis agent, induces high levels of granulocyte colony-stimulating factor. | 2012 | Int. Immunopharmacol. | pmid:23000517 |