MeSH term | MeSH ID | Detail |
---|---|---|
Hypercholesterolemia | D006937 | 91 associated lipids |
Total
1
Gamma-tocotrienol is a lipid of Prenol Lipids (PR) class.
We collected disease MeSH terms mapped to the references associated with gamma-tocotrienol
MeSH term | MeSH ID | Detail |
---|---|---|
Hypercholesterolemia | D006937 | 91 associated lipids |
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Sylvester PW et al. | Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation. | 2001 | Cell Prolif. | pmid:11736999 |
Kunnumakkara AB et al. | {Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment. | 2010 | Cancer Res. | pmid:20864511 |
Yap WN et al. | Id1, inhibitor of differentiation, is a key protein mediating anti-tumor responses of gamma-tocotrienol in breast cancer cells. | 2010 | Cancer Lett. | pmid:19926394 |
Tuerdi G et al. | Synergistic effect of combined treatment with gamma-tocotrienol and statin on human malignant mesothelioma cells. | 2013 | Cancer Lett. | pmid:23879968 |
Gopalan A et al. | Eliminating drug resistant breast cancer stem-like cells with combination of simvastatin and gamma-tocotrienol. | 2013 | Cancer Lett. | pmid:23063651 |
Hermizi H et al. | Beneficial effects of tocotrienol and tocopherol on bone histomorphometric parameters in sprague-dawley male rats after nicotine cessation. | 2009 | Calcif. Tissue Int. | pmid:19020790 |
Rajendran P et al. | γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent. | 2011 | Br. J. Pharmacol. | pmid:21198544 |
Sun W et al. | Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling. | 2008 | Br. J. Nutr. | pmid:18081943 |
Yap WN et al. | Gamma-tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways. | 2008 | Br. J. Cancer | pmid:19002171 |
Prasad S et al. | γ-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules. | 2016 | Br. J. Cancer | pmid:27575851 |
Zainuddin A et al. | Effect of experimental treatment on GAPDH mRNA expression as a housekeeping gene in human diploid fibroblasts. | 2010 | BMC Mol. Biol. | pmid:20707929 |
Lim SW et al. | Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells. | 2014 | BMC Complement Altern Med | pmid:25480449 |
Abdul Rahman A et al. | Gamma-tocotrienol and hydroxy-chavicol synergistically inhibits growth and induces apoptosis of human glioma cells. | 2014 | BMC Complement Altern Med | pmid:24980711 |
Liu J et al. | Polysaccharopeptide enhanced the anti-cancer effect of gamma-tocotrienol through activation of AMPK. | 2014 | BMC Complement Altern Med | pmid:25129068 |
Abdul Rahman Sazli F et al. | Gamma-tocotrienol treatment increased peroxiredoxin-4 expression in HepG2 liver cancer cell line. | 2015 | BMC Complement Altern Med | pmid:25886747 |
Bachawal SV et al. | Enhanced antiproliferative and apoptotic response to combined treatment of gamma-tocotrienol with erlotinib or gefitinib in mammary tumor cells. | 2010 | BMC Cancer | pmid:20211018 |
Gu W et al. | Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway. | 2015 | BMC Cancer | pmid:26315028 |
Zhifang M et al. | The androgen receptor plays a suppressive role in epithelial- mesenchymal transition of human prostate cancer stem progenitor cells. | 2015 | BMC Biochem. | pmid:25943311 |
Kawakami Y et al. | Distribution of tocotrienols in rats fed a rice bran tocotrienol concentrate. | 2007 | Biosci. Biotechnol. Biochem. | pmid:17284857 |
Shirode AB and Sylvester PW | Synergistic anticancer effects of combined gamma-tocotrienol and celecoxib treatment are associated with suppression in Akt and NFkappaB signaling. | 2010 | Biomed. Pharmacother. | pmid:19954924 |
Liang S et al. | Development and validation of a sensitive LC/MS/MS method for the determination of γ-tocotrienol in rat plasma: application to pharmacokinetic studies. | 2013 | Biomed. Chromatogr. | pmid:22522964 |
Abuasal B et al. | Development and validation of a reversed-phase HPLC method for the determination of γ-tocotrienol in rat and human plasma. | 2011 | Biomed. Chromatogr. | pmid:20734323 |
Algayadh IG et al. | Role of Rac1/WAVE2 Signaling in Mediating the Inhibitory Effects of γ-Tocotrienol on Mammary Cancer Cell Migration and Invasion. | 2016 | Biol. Pharm. Bull. | pmid:27904039 |
Parajuli P et al. | Anticancer Effects of γ-Tocotrienol Are Associated with a Suppression in Aerobic Glycolysis. | 2015 | Biol. Pharm. Bull. | pmid:26328490 |
Hattori A et al. | Production of LLU-alpha following an oral administration of gamma-tocotrienol or gamma-tocopherol to rats. | 2000 | Biol. Pharm. Bull. | pmid:11085376 |
Nowicka B et al. | Function of plastochromanol and other biological prenyllipids in the inhibition of lipid peroxidation-A comparative study in model systems. | 2013 | Biochim. Biophys. Acta | pmid:22959712 |
Suarna C et al. | Comparative antioxidant activity of tocotrienols and other natural lipid-soluble antioxidants in a homogeneous system, and in rat and human lipoproteins. | 1993 | Biochim. Biophys. Acta | pmid:8443232 |
Zbierzak AM et al. | Intersection of the tocopherol and plastoquinol metabolic pathways at the plastoglobule. | 2010 | Biochem. J. | pmid:19843012 |
Krycer JR et al. | A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products. | 2012 | Biochem. J. | pmid:22657538 |
Shah SJ and Sylvester PW | Tocotrienol-induced cytotoxicity is unrelated to mitochondrial stress apoptotic signaling in neoplastic mammary epithelial cells. | 2005 | Biochem. Cell Biol. | pmid:15746970 |
Wang Q et al. | Effects of tocotrienol on the intracellular translocation and degradation of apolipoprotein B: possible involvement of a proteasome independent pathway. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9618265 |
Yamashita S et al. | γ-Tocotrienol upregulates aryl hydrocarbon receptor expression and enhances the anticancer effect of baicalein. | 2016 | Biochem. Biophys. Res. Commun. | pmid:27055589 |
Li F et al. | Tocotrienol enriched palm oil prevents atherosclerosis through modulating the activities of peroxisome proliferators-activated receptors. | 2010 | Atherosclerosis | pmid:20138624 |
Pintha K et al. | Anti-invasive activity against cancer cells of phytochemicals in red jasmine rice (Oryza sativa L.). | 2014 | Asian Pac. J. Cancer Prev. | pmid:24969892 |
Theriault A et al. | Effects of gamma-tocotrienol on ApoB synthesis, degradation, and secretion in HepG2 cells. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:10073977 |
Wali VB et al. | Endoplasmic reticulum stress mediates gamma-tocotrienol-induced apoptosis in mammary tumor cells. | 2009 | Apoptosis | pmid:19771520 |
Bachawal SV et al. | Combined gamma-tocotrienol and erlotinib/gefitinib treatment suppresses Stat and Akt signaling in murine mammary tumor cells. | 2010 | Anticancer Res. | pmid:20332450 |
Ananthula S et al. | Oxazine derivatives of γ- and δ-tocotrienol display enhanced anticancer activity in vivo. | 2014 | Anticancer Res. | pmid:24922632 |
Hsieh TC et al. | gamma-Tocotrienol controls proliferation, modulates expression of cell cycle regulatory proteins and up-regulates quinone reductase NQO2 in MCF-7 breast cancer cells. | 2010 | Anticancer Res. | pmid:20683025 |
Raederstorff D et al. | Effect of either gamma-tocotrienol or a tocotrienol mixture on the plasma lipid profile in hamsters. | 2002 | Ann. Nutr. Metab. | pmid:11914511 |
Conte C et al. | Gamma-tocotrienol metabolism and antiproliferative effect in prostate cancer cells. | 2004 | Ann. N. Y. Acad. Sci. | pmid:15753178 |
Mustad VA et al. | Supplementation with 3 compositionally different tocotrienol supplements does not improve cardiovascular disease risk factors in men and women with hypercholesterolemia. | 2002 | Am. J. Clin. Nutr. | pmid:12450888 |
Qureshi AA et al. | Lowering of serum cholesterol in hypercholesterolemic humans by tocotrienols (palmvitee). | 1991 | Am. J. Clin. Nutr. | pmid:2012010 |
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