MeSH term | MeSH ID | Detail |
---|---|---|
Hypercholesterolemia | D006937 | 91 associated lipids |
Total
1
Gamma-tocotrienol is a lipid of Prenol Lipids (PR) class.
We collected disease MeSH terms mapped to the references associated with gamma-tocotrienol
MeSH term | MeSH ID | Detail |
---|---|---|
Hypercholesterolemia | D006937 | 91 associated lipids |
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Zaiden N et al. | Gamma delta tocotrienols reduce hepatic triglyceride synthesis and VLDL secretion. | 2010 | J. Atheroscler. Thromb. | pmid:20702976 |
Shibata A et al. | Suppression of gamma-tocotrienol on UVB induced inflammation in HaCaT keratinocytes and HR-1 hairless mice via inflammatory mediators multiple signaling. | 2010 | J. Agric. Food Chem. | pmid:20465215 |
Goffman FD and Möllers C | Changes in tocopherol and plastochromanol-8 contents in seeds and oil of oilseed rape (Brassica napus L.) during storage as influenced by temperature and air oxygen. | 2000 | J. Agric. Food Chem. | pmid:10820066 |
Berbee M et al. | Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin. | 2011 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:20950957 |
Ghosh SP et al. | Gamma-tocotrienol, a tocol antioxidant as a potent radioprotector. | 2009 | Int. J. Radiat. Biol. | pmid:19557601 |
Hsieh TC and Wu JM | Suppression of cell proliferation and gene expression by combinatorial synergy of EGCG, resveratrol and gamma-tocotrienol in estrogen receptor-positive MCF-7 breast cancer cells. | 2008 | Int. J. Oncol. | pmid:18813800 |
Kani K et al. | γ-tocotrienol enhances the chemosensitivity of human oral cancer cells to docetaxel through the downregulation of the expression of NF-κB-regulated anti-apoptotic gene products. | 2013 | Int. J. Oncol. | pmid:23138939 |
Luk SU et al. | Gamma-tocotrienol as an effective agent in targeting prostate cancer stem cell-like population. | 2011 | Int. J. Cancer | pmid:20617516 |
Yang Z et al. | Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. | 2010 | Int. J. Cancer | pmid:19626588 |
Jiang Q et al. | Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide. | 2012 | Int. J. Cancer | pmid:21400505 |
Ray S et al. | Mobilization of progenitor cells into peripheral blood by gamma-tocotrienol: a promising radiation countermeasure. | 2013 | Int. Immunopharmacol. | pmid:23415908 |
Kulkarni SS et al. | Gamma-tocotrienol, a radiation prophylaxis agent, induces high levels of granulocyte colony-stimulating factor. | 2012 | Int. Immunopharmacol. | pmid:23000517 |
Brooks R et al. | Direct inhibition of osteoclast formation and activity by the vitamin E isomer gamma-tocotrienol. | 2011 | Int J Vitam Nutr Res | pmid:22673919 |
Yap SP and Yuen KH | Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations. | 2004 | Int J Pharm | pmid:15288344 |
Ledet GA et al. | Development of Orally Administered γ-Tocotrienol (GT3) Nanoemulsion for Radioprotection. | 2016 | Int J Mol Sci | pmid:28029115 |
Pathak R et al. | The Vitamin E Analog Gamma-Tocotrienol (GT3) and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM). | 2016 | Int J Mol Sci | pmid:27869747 |
Singh VK and Hauer-Jensen M | γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. | 2016 | Int J Mol Sci | pmid:27153057 |
Singh VK et al. | Progenitor Cell Mobilization by Gamma-tocotrienol: A Promising Radiation Countermeasure. | 2016 | Health Phys | pmid:27356050 |
Makpol S et al. | Different starting times of alpha-tocopherol and gamma-tocotrienol supplementation and tumor marker enzyme activities in the rat chemically induced with cancer. | 1997 | Gen. Pharmacol. | pmid:9147029 |
Fukui K et al. | Tocotrienols prevent hydrogen peroxide-induced axon and dendrite degeneration in cerebellar granule cells. | 2012 | Free Radic. Res. | pmid:22149330 |
Fuchs J et al. | HPLC analysis of vitamin E isoforms in human epidermis: correlation with minimal erythema dose and free radical scavenging activity. | 2003 | Free Radic. Biol. Med. | pmid:12543248 |
Katsanidis E and Addis PB | Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue. | 1999 | Free Radic. Biol. Med. | pmid:10641704 |
Wilankar C et al. | Role of immunoregulatory transcription factors in differential immunomodulatory effects of tocotrienols. | 2011 | Free Radic. Biol. Med. | pmid:21536125 |
Campbell SE et al. | γ-Tocotrienol induces growth arrest through a novel pathway with TGFβ2 in prostate cancer. | 2011 | Free Radic. Biol. Med. | pmid:21335085 |
Nakamura H et al. | Oral toxicity of a tocotrienol preparation in rats. | 2001 | Food Chem. Toxicol. | pmid:11434987 |
Abuznait AH et al. | Induction of expression and functional activity of P-glycoprotein efflux transporter by bioactive plant natural products. | 2011 | Food Chem. Toxicol. | pmid:21851848 |
Wu SJ et al. | γ-Tocotrienol induced cell cycle arrest and apoptosis via activating the Bax-mediated mitochondrial and AMPK signaling pathways in 3T3-L1 adipocytes. | 2013 | Food Chem. Toxicol. | pmid:23816832 |
Suman S et al. | Gamma tocotrienol, a potent radioprotector, preferentially upregulates expression of anti-apoptotic genes to promote intestinal cell survival. | 2013 | Food Chem. Toxicol. | pmid:23941772 |
Akl MR et al. | Sesamin synergistically potentiates the anticancer effects of γ-tocotrienol in mammary cancer cell lines. | 2013 | Fitoterapia | pmid:23266736 |
Shah SJ and Sylvester PW | Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity. | 2005 | Exp. Biol. Med. (Maywood) | pmid:15792944 |
Tiwari RV et al. | γ-Tocotrienol-induced autophagy in malignant mammary cancer cells. | 2014 | Exp. Biol. Med. (Maywood) | pmid:24231340 |
Wali VB et al. | Combined treatment of gamma-tocotrienol with statins induce mammary tumor cell cycle arrest in G1. | 2009 | Exp. Biol. Med. (Maywood) | pmid:19359655 |
Abuasal B et al. | Intestinal absorption of gamma-tocotrienol is mediated by Niemann-Pick C1-like 1: in situ rat intestinal perfusion studies. | 2010 | Drug Metab. Dispos. | pmid:20207946 |
Akaho N et al. | Preparation and in vivo evaluation of a water-soluble prodrug for 2R-gamma-tocotrienol and as a two-step prodrug for 2,7,8-trimethyl-2S-(beta-carboxyethyl)-6-hydroxychroman (S-gamma-CEHC) in rat. | 2007 | Drug Metab. Dispos. | pmid:17537874 |
Zhou C et al. | Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. | 2004 | Drug Metab. Dispos. | pmid:15269186 |
Kulkarni S et al. | Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure. | 2013 | Cytokine | pmid:23561424 |
Wilankar C et al. | γ-Tocotrienol induces apoptosis in human T cell lymphoma through activation of both intrinsic and extrinsic pathways. | 2011 | Curr. Pharm. Des. | pmid:21774779 |
Berbée M and Hauer-Jensen M | Novel drugs to ameliorate gastrointestinal normal tissue radiation toxicity in clinical practice: what is emerging from the laboratory? | 2012 | Curr Opin Support Palliat Care | pmid:22228028 |
Kulkarni S et al. | Hematological targets of radiation damage. | 2010 | Curr Drug Targets | pmid:20583980 |
Ong FB et al. | Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol. | 1993 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:7903615 |
Makpol S et al. | Gamma-tocotrienol modulation of senescence-associated gene expression prevents cellular aging in human diploid fibroblasts. | 2012 | Clinics (Sao Paulo) | pmid:22358238 |
Newaz MA and Nawal NN | Effect of gamma-tocotrienol on blood pressure, lipid peroxidation and total antioxidant status in spontaneously hypertensive rats (SHR). | 1999 | Clin. Exp. Hypertens. | pmid:10574414 |
Manu KA et al. | First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway. | 2012 | Clin. Cancer Res. | pmid:22351692 |
Then SM et al. | Is vitamin E toxic to neuron cells? | 2009 | Cell. Mol. Neurobiol. | pmid:19172392 |
Tan SW et al. | Inhibitory effects of palm α-, γ- and δ-tocotrienol on lipopolysaccharide-induced nitric oxide production in BV2 microglia. | 2011 | Cell. Immunol. | pmid:21839427 |
Samant GV et al. | Anti-proliferative effects of gamma-tocotrienol on mammary tumour cells are associated with suppression of cell cycle progression. | 2010 | Cell Prolif. | pmid:19922488 |
Samant GV and Sylvester PW | gamma-Tocotrienol inhibits ErbB3-dependent PI3K/Akt mitogenic signalling in neoplastic mammary epithelial cells. | 2006 | Cell Prolif. | pmid:17109639 |
Ayoub NM et al. | γ-Tocotrienol inhibits HGF-dependent mitogenesis and Met activation in highly malignant mammary tumour cells. | 2011 | Cell Prolif. | pmid:21973114 |
Ayoub NM et al. | Combined γ-tocotrienol and Met inhibitor treatment suppresses mammary cancer cell proliferation, epithelial-to-mesenchymal transition and migration. | 2013 | Cell Prolif. | pmid:24033536 |
Loganathan R et al. | Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity. | 2013 | Cell Prolif. | pmid:23510475 |