| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
Total
1
gamma-tocotrienol
Gamma-tocotrienol is a lipid of Prenol Lipids (PR) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 1076 references associated with gamma-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for gamma-tocotrienol
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-tocotrienol
PubChem Biomolecular Interactions and Pathways
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All references with gamma-tocotrienol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mao Y et al. | Chemical Composition Analysis, Sensory, and Feasibility Study of Tree Peony Seed. | 2017 | J. Food Sci. | pmid:28135396 |
| Ding Y et al. | Gamma-tocotrienol reverses multidrug resistance of breast cancer cells with a mechanism distinct from that of atorvastatin. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:27864002 |
| Jang Y et al. | Gamma-tocotrienol profoundly alters sphingolipids in cancer cells by inhibition of dihydroceramide desaturase and possibly activation of sphingolipid hydrolysis during prolonged treatment. | 2017 | J. Nutr. Biochem. | pmid:28456081 |
| Zhao L et al. | Regulation of Obesity and Metabolic Complications by Gamma and Delta Tocotrienols. | 2016 | Molecules | pmid:26978344 |
| Ledet GA et al. | Development of Orally Administered γ-Tocotrienol (GT3) Nanoemulsion for Radioprotection. | 2016 | Int J Mol Sci | pmid:28029115 |
| Algayadh IG et al. | Role of Rac1/WAVE2 Signaling in Mediating the Inhibitory Effects of γ-Tocotrienol on Mammary Cancer Cell Migration and Invasion. | 2016 | Biol. Pharm. Bull. | pmid:27904039 |
| Pathak R et al. | The Vitamin E Analog Gamma-Tocotrienol (GT3) and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM). | 2016 | Int J Mol Sci | pmid:27869747 |
| Prasad S et al. | γ-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules. | 2016 | Br. J. Cancer | pmid:27575851 |
| Dłużewska J et al. | Tocopherol Cyclases-Substrate Specificity and Phylogenetic Relations. | 2016 | PLoS ONE | pmid:27462710 |
| Strenkert D et al. | Genetically Programmed Changes in Photosynthetic Cofactor Metabolism in Copper-deficient Chlamydomonas. | 2016 | J. Biol. Chem. | pmid:27440043 |
| Singh VK et al. | Progenitor Cell Mobilization by Gamma-tocotrienol: A Promising Radiation Countermeasure. | 2016 | Health Phys | pmid:27356050 |
| Singh VK and Hauer-Jensen M | γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. | 2016 | Int J Mol Sci | pmid:27153057 |
| Kim Y et al. | Suppression of NLRP3 inflammasome by γ-tocotrienol ameliorates type 2 diabetes. | 2016 | J. Lipid Res. | pmid:26628639 |
| Yamashita S et al. | γ-Tocotrienol upregulates aryl hydrocarbon receptor expression and enhances the anticancer effect of baicalein. | 2016 | Biochem. Biophys. Res. Commun. | pmid:27055589 |
| Meganathan P et al. | A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to existing Tocotrienol-Rich Fraction in healthy human subjects. | 2015 | Sci Rep | pmid:26323969 |
| Kim EH et al. | Fibrillin 5 Is Essential for Plastoquinone-9 Biosynthesis by Binding to Solanesyl Diphosphate Synthases in Arabidopsis. | 2015 | Plant Cell | pmid:26432861 |
| Parajuli P et al. | Anticancer Effects of γ-Tocotrienol Are Associated with a Suppression in Aerobic Glycolysis. | 2015 | Biol. Pharm. Bull. | pmid:26328490 |
| Gu W et al. | Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway. | 2015 | BMC Cancer | pmid:26315028 |
| Yusof KM et al. | γ-Tocotrienol and 6-Gingerol in Combination Synergistically Induce Cytotoxicity and Apoptosis in HT-29 and SW837 Human Colorectal Cancer Cells. | 2015 | Molecules | pmid:26046324 |
| Peh HY et al. | Vitamin E Isoform γ-Tocotrienol Downregulates House Dust Mite-Induced Asthma. | 2015 | J. Immunol. | pmid:26041537 |
| Zhifang M et al. | The androgen receptor plays a suppressive role in epithelial- mesenchymal transition of human prostate cancer stem progenitor cells. | 2015 | BMC Biochem. | pmid:25943311 |
| Abdul Rahman Sazli F et al. | Gamma-tocotrienol treatment increased peroxiredoxin-4 expression in HepG2 liver cancer cell line. | 2015 | BMC Complement Altern Med | pmid:25886747 |
| Lim SW et al. | Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells. | 2014 | BMC Complement Altern Med | pmid:25480449 |
| Tiwari RV et al. | γ-Tocotrienol-induced autophagy in malignant mammary cancer cells. | 2014 | Exp. Biol. Med. (Maywood) | pmid:24231340 |
| Abdul Rahman A et al. | Gamma-tocotrienol and hydroxy-chavicol synergistically inhibits growth and induces apoptosis of human glioma cells. | 2014 | BMC Complement Altern Med | pmid:24980711 |
| Liu J et al. | Polysaccharopeptide enhanced the anti-cancer effect of gamma-tocotrienol through activation of AMPK. | 2014 | BMC Complement Altern Med | pmid:25129068 |
| Singh VK et al. | Progenitors mobilized by gamma-tocotrienol as an effective radiation countermeasure. | 2014 | PLoS ONE | pmid:25423021 |
| Pintha K et al. | Anti-invasive activity against cancer cells of phytochemicals in red jasmine rice (Oryza sativa L.). | 2014 | Asian Pac. J. Cancer Prev. | pmid:24969892 |
| Siveen KS et al. | Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model. | 2014 | Oncotarget | pmid:24722367 |
| Ananthula S et al. | Oxazine derivatives of γ- and δ-tocotrienol display enhanced anticancer activity in vivo. | 2014 | Anticancer Res. | pmid:24922632 |
| Deng L et al. | Tissue distribution of emulsified γ-tocotrienol and its long-term biological effects after subcutaneous administration. | 2014 | Lipids Health Dis | pmid:24712339 |
| Kaup RM et al. | Antidiabetic effects of a standardized Egyptian rice bran extract. | 2013 | Phytother Res | pmid:22566008 |
| Liang S et al. | Development and validation of a sensitive LC/MS/MS method for the determination of γ-tocotrienol in rat plasma: application to pharmacokinetic studies. | 2013 | Biomed. Chromatogr. | pmid:22522964 |
| Nowicka B et al. | Function of plastochromanol and other biological prenyllipids in the inhibition of lipid peroxidation-A comparative study in model systems. | 2013 | Biochim. Biophys. Acta | pmid:22959712 |
| Kamsani YS et al. | Nicotine-induced cessation of embryonic development is reversed by γ-tocotrienol in mice. | 2013 | Med Sci Monit Basic Res | pmid:23462735 |
| Zhang JS et al. | γ-Tocotrienol induces paraptosis-like cell death in human colon carcinoma SW620 cells. | 2013 | PLoS ONE | pmid:23469066 |
| Mangialasche F et al. | Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol. | 2013 | J. Intern. Med. | pmid:23343471 |
| Ray S et al. | Mobilization of progenitor cells into peripheral blood by gamma-tocotrienol: a promising radiation countermeasure. | 2013 | Int. Immunopharmacol. | pmid:23415908 |
| Tuerdi G et al. | Synergistic effect of combined treatment with gamma-tocotrienol and statin on human malignant mesothelioma cells. | 2013 | Cancer Lett. | pmid:23879968 |
| Wu SJ et al. | γ-Tocotrienol induced cell cycle arrest and apoptosis via activating the Bax-mediated mitochondrial and AMPK signaling pathways in 3T3-L1 adipocytes. | 2013 | Food Chem. Toxicol. | pmid:23816832 |
| Makpol S et al. | Gamma-tocotrienol modulated gene expression in senescent human diploid fibroblasts as revealed by microarray analysis. | 2013 | Oxid Med Cell Longev | pmid:23634235 |
| Wang Y and Jiang Q | γ-Tocotrienol inhibits lipopolysaccharide-induced interlukin-6 and granulocyte colony-stimulating factor by suppressing C/EBPβ and NF-κB in macrophages. | 2013 | J. Nutr. Biochem. | pmid:23246159 |
| Akl MR et al. | Sesamin synergistically potentiates the anticancer effects of γ-tocotrienol in mammary cancer cell lines. | 2013 | Fitoterapia | pmid:23266736 |
| Gopalan A et al. | Eliminating drug resistant breast cancer stem-like cells with combination of simvastatin and gamma-tocotrienol. | 2013 | Cancer Lett. | pmid:23063651 |
| Kulkarni S et al. | Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure. | 2013 | Cytokine | pmid:23561424 |
| Burdeos GC et al. | γ-Tocotrienol attenuates triglyceride through effect on lipogenic gene expressions in mouse hepatocellular carcinoma Hepa 1-6. | 2013 | J. Nutr. Sci. Vitaminol. | pmid:23727646 |
| Block A et al. | Functional modeling identifies paralogous solanesyl-diphosphate synthases that assemble the side chain of plastoquinone-9 in plastids. | 2013 | J. Biol. Chem. | pmid:23913686 |
| Suman S et al. | Gamma tocotrienol, a potent radioprotector, preferentially upregulates expression of anti-apoptotic genes to promote intestinal cell survival. | 2013 | Food Chem. Toxicol. | pmid:23941772 |
| Ayoub NM et al. | Combined γ-tocotrienol and Met inhibitor treatment suppresses mammary cancer cell proliferation, epithelial-to-mesenchymal transition and migration. | 2013 | Cell Prolif. | pmid:24033536 |
| Martinis J et al. | A chloroplast ABC1-like kinase regulates vitamin E metabolism in Arabidopsis. | 2013 | Plant Physiol. | pmid:23632854 |
| Rodzian MN et al. | Pure tocotrienol concentrate protected rat gastric mucosa from acute stress-induced injury by a non-antioxidant mechanism. | 2013 | Pol J Pathol | pmid:23625601 |
| Loganathan R et al. | Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity. | 2013 | Cell Prolif. | pmid:23510475 |
| Kani K et al. | γ-tocotrienol enhances the chemosensitivity of human oral cancer cells to docetaxel through the downregulation of the expression of NF-κB-regulated anti-apoptotic gene products. | 2013 | Int. J. Oncol. | pmid:23138939 |
| Nowak G et al. | γ-Tocotrienol protects against mitochondrial dysfunction and renal cell death. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22040679 |
| Wang Y et al. | Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells. | 2012 | J. Nutr. Biochem. | pmid:21764283 |
| Xu W et al. | γ-Tocotrienol inhibits cell viability through suppression of β-catenin/Tcf signaling in human colon carcinoma HT-29 cells. | 2012 | J. Nutr. Biochem. | pmid:21852086 |
| Matsunaga T et al. | γ-Tocotrienol attenuates TNF-α-induced changes in secretion and gene expression of MCP-1, IL-6 and adiponectin in 3T3-L1 adipocytes. | 2012 | Mol Med Rep | pmid:22293775 |
| Mukhopadhyay P et al. | Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. | 2012 | J. Cell. Mol. Med. | pmid:22050707 |
| Uchida T et al. | Tissue distribution of α- and γ-tocotrienol and γ-tocopherol in rats and interference with their accumulation by α-tocopherol. | 2012 | Lipids | pmid:22042641 |
| Das S et al. | Tocotrienols confer resistance to ischemia in hypercholesterolemic hearts: insight with genomics. | 2012 | Mol. Cell. Biochem. | pmid:21918828 |
| Abuasal BS et al. | Enhancement of intestinal permeability utilizing solid lipid nanoparticles increases γ-tocotrienol oral bioavailability. | 2012 | Lipids | pmid:22271424 |
| Makpol S et al. | Inhibition of mitochondrial cytochrome c release and suppression of caspases by gamma-tocotrienol prevent apoptosis and delay aging in stress-induced premature senescence of skin fibroblasts. | 2012 | Oxid Med Cell Longev | pmid:22919441 |
| Berbée M and Hauer-Jensen M | Novel drugs to ameliorate gastrointestinal normal tissue radiation toxicity in clinical practice: what is emerging from the laboratory? | 2012 | Curr Opin Support Palliat Care | pmid:22228028 |
| Fukui K et al. | Tocotrienols prevent hydrogen peroxide-induced axon and dendrite degeneration in cerebellar granule cells. | 2012 | Free Radic. Res. | pmid:22149330 |
| Manu KA et al. | First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway. | 2012 | Clin. Cancer Res. | pmid:22351692 |
| Wong RS et al. | δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells. | 2012 | Microsc. Microanal. | pmid:22640960 |
| Makpol S et al. | Gamma-tocotrienol modulation of senescence-associated gene expression prevents cellular aging in human diploid fibroblasts. | 2012 | Clinics (Sao Paulo) | pmid:22358238 |
| Szymańska R | [Chloroplast prenylated lipids in response to stress in plants]. | 2012 | Postepy Biochem. | pmid:23662431 |
| Akl MR et al. | Mechanisms mediating the synergistic anticancer effects of combined γ-tocotrienol and sesamin treatment. | 2012 | Planta Med. | pmid:22987298 |
| Gopalan A et al. | Involvement of de novo ceramide synthesis in gamma-tocopherol and gamma-tocotrienol-induced apoptosis in human breast cancer cells. | 2012 | Mol Nutr Food Res | pmid:23065795 |
| Kulkarni SS et al. | Gamma-tocotrienol, a radiation prophylaxis agent, induces high levels of granulocyte colony-stimulating factor. | 2012 | Int. Immunopharmacol. | pmid:23000517 |
| Krycer JR et al. | A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products. | 2012 | Biochem. J. | pmid:22657538 |
| Xiong A et al. | Distinct roles of different forms of vitamin E in DHA-induced apoptosis in triple-negative breast cancer cells. | 2012 | Mol Nutr Food Res | pmid:22707267 |
| Patacsil D et al. | Gamma-tocotrienol induced apoptosis is associated with unfolded protein response in human breast cancer cells. | 2012 | J. Nutr. Biochem. | pmid:21429729 |
| Jiang Q et al. | Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide. | 2012 | Int. J. Cancer | pmid:21400505 |
| Luk SU et al. | Gamma-tocotrienol as an effective agent in targeting prostate cancer stem cell-like population. | 2011 | Int. J. Cancer | pmid:20617516 |
| Wilankar C et al. | γ-Tocotrienol induces apoptosis in human T cell lymphoma through activation of both intrinsic and extrinsic pathways. | 2011 | Curr. Pharm. Des. | pmid:21774779 |
| Abuznait AH et al. | Induction of expression and functional activity of P-glycoprotein efflux transporter by bioactive plant natural products. | 2011 | Food Chem. Toxicol. | pmid:21851848 |
| Eugeni Piller L et al. | Chloroplast lipid droplet type II NAD(P)H quinone oxidoreductase is essential for prenylquinone metabolism and vitamin K1 accumulation. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21844348 |
| Wilankar C et al. | Role of immunoregulatory transcription factors in differential immunomodulatory effects of tocotrienols. | 2011 | Free Radic. Biol. Med. | pmid:21536125 |
| Tan SW et al. | Inhibitory effects of palm α-, γ- and δ-tocotrienol on lipopolysaccharide-induced nitric oxide production in BV2 microglia. | 2011 | Cell. Immunol. | pmid:21839427 |
| Uchida T et al. | Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol. | 2011 | J. Nutr. Sci. Vitaminol. | pmid:22293209 |
| Ayoub NM et al. | γ-Tocotrienol inhibits HGF-dependent mitogenesis and Met activation in highly malignant mammary tumour cells. | 2011 | Cell Prolif. | pmid:21973114 |
| Rajendran P et al. | γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent. | 2011 | Br. J. Pharmacol. | pmid:21198544 |
| Brooks R et al. | Direct inhibition of osteoclast formation and activity by the vitamin E isomer gamma-tocotrienol. | 2011 | Int J Vitam Nutr Res | pmid:22673919 |
| Abuasal B et al. | Development and validation of a reversed-phase HPLC method for the determination of γ-tocotrienol in rat and human plasma. | 2011 | Biomed. Chromatogr. | pmid:20734323 |
| Inoue A et al. | Induction of apoptosis by γ-tocotrienol in human cancer cell lines and leukemic blasts from patients: dependency on Bid, cytochrome c, and caspase pathway. | 2011 | Nutr Cancer | pmid:21660856 |
| Campbell SE et al. | γ-Tocotrienol induces growth arrest through a novel pathway with TGFβ2 in prostate cancer. | 2011 | Free Radic. Biol. Med. | pmid:21335085 |
| Berbée M et al. | Pentoxifylline enhances the radioprotective properties of γ-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems. | 2011 | Radiat. Res. | pmid:21388273 |
| Berbee M et al. | Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin. | 2011 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:20950957 |
| Li Y et al. | γ-Tocotrienol inhibits angiogenesis of human umbilical vein endothelial cell induced by cancer cell. | 2011 | J. Nutr. Biochem. | pmid:21292465 |
| Miyoshi N et al. | The enhancement of the oral bioavailability of γ-tocotrienol in mice by γ-cyclodextrin inclusion. | 2011 | J. Nutr. Biochem. | pmid:21292469 |
| Bi S et al. | gamma-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line. | 2010 Jul-Aug | Toxicology | pmid:20452389 |
| Makpol S et al. | gamma-Tocotrienol prevents oxidative stress-induced telomere shortening in human fibroblasts derived from different aged individuals. | 2010 Jan-Feb | Oxid Med Cell Longev | pmid:20716926 |
| Yap WN et al. | In vivo evidence of gamma-tocotrienol as a chemosensitizer in the treatment of hormone-refractory prostate cancer. | 2010 | Pharmacology | pmid:20375535 |
| Abuasal B et al. | Intestinal absorption of gamma-tocotrienol is mediated by Niemann-Pick C1-like 1: in situ rat intestinal perfusion studies. | 2010 | Drug Metab. Dispos. | pmid:20207946 |
| Bachawal SV et al. | Combined gamma-tocotrienol and erlotinib/gefitinib treatment suppresses Stat and Akt signaling in murine mammary tumor cells. | 2010 | Anticancer Res. | pmid:20332450 |
| Zainuddin A et al. | Effect of experimental treatment on GAPDH mRNA expression as a housekeeping gene in human diploid fibroblasts. | 2010 | BMC Mol. Biol. | pmid:20707929 |
| Liu HK et al. | Inhibitory effects of gamma-tocotrienol on invasion and metastasis of human gastric adenocarcinoma SGC-7901 cells. | 2010 | J. Nutr. Biochem. | pmid:19195866 |
| Shuid AN et al. | Vitamin E exhibits bone anabolic actions in normal male rats. | 2010 | J. Bone Miner. Metab. | pmid:19779668 |