| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
Total
1
gamma-tocotrienol
Gamma-tocotrienol is a lipid of Prenol Lipids (PR) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 1076 references associated with gamma-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for gamma-tocotrienol
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-tocotrienol
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with gamma-tocotrienol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bi S et al. | gamma-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line. | 2010 Jul-Aug | Toxicology | pmid:20452389 |
| Meganathan P et al. | A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to existing Tocotrienol-Rich Fraction in healthy human subjects. | 2015 | Sci Rep | pmid:26323969 |
| Berbée M et al. | gamma-Tocotrienol ameliorates intestinal radiation injury and reduces vascular oxidative stress after total-body irradiation by an HMG-CoA reductase-dependent mechanism. | 2009 | Radiat. Res. | pmid:19580495 |
| Kulkarni S et al. | Gamma-tocotrienol protects hematopoietic stem and progenitor cells in mice after total-body irradiation. | 2010 | Radiat. Res. | pmid:20518653 |
| Berbée M et al. | Pentoxifylline enhances the radioprotective properties of γ-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems. | 2011 | Radiat. Res. | pmid:21388273 |
| Jiang Q et al. | Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19074288 |
| Eugeni Piller L et al. | Chloroplast lipid droplet type II NAD(P)H quinone oxidoreductase is essential for prenylquinone metabolism and vitamin K1 accumulation. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21844348 |
| Mène-Saffrané L et al. | Plastochromanol-8 and tocopherols are essential lipid-soluble antioxidants during seed desiccation and quiescence in Arabidopsis. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20837525 |
| Szymańska R and Kruk J | [Occurrence and function of tocochromanols in plants, animals and men]. | 2007 | Postepy Biochem. | pmid:17969879 |
| Szymańska R | [Chloroplast prenylated lipids in response to stress in plants]. | 2012 | Postepy Biochem. | pmid:23662431 |
| Rodzian MN et al. | Pure tocotrienol concentrate protected rat gastric mucosa from acute stress-induced injury by a non-antioxidant mechanism. | 2013 | Pol J Pathol | pmid:23625601 |
| Zhang JS et al. | γ-Tocotrienol induces paraptosis-like cell death in human colon carcinoma SW620 cells. | 2013 | PLoS ONE | pmid:23469066 |
| Dłużewska J et al. | Tocopherol Cyclases-Substrate Specificity and Phylogenetic Relations. | 2016 | PLoS ONE | pmid:27462710 |
| Singh VK et al. | Progenitors mobilized by gamma-tocotrienol as an effective radiation countermeasure. | 2014 | PLoS ONE | pmid:25423021 |
| Akl MR et al. | Mechanisms mediating the synergistic anticancer effects of combined γ-tocotrienol and sesamin treatment. | 2012 | Planta Med. | pmid:22987298 |
| Martinis J et al. | A chloroplast ABC1-like kinase regulates vitamin E metabolism in Arabidopsis. | 2013 | Plant Physiol. | pmid:23632854 |
| Kim EH et al. | Fibrillin 5 Is Essential for Plastoquinone-9 Biosynthesis by Binding to Solanesyl Diphosphate Synthases in Arabidopsis. | 2015 | Plant Cell | pmid:26432861 |
| Yap WN et al. | Gamma- and delta-tocotrienols inhibit skin melanin synthesis by suppressing constitutive and UV-induced tyrosinase activation. | 2010 | Pigment Cell Melanoma Res | pmid:20609176 |
| Nakashima K et al. | The tocotrienol-rich fraction from rice bran enhances cisplatin-induced cytotoxicity in human mesothelioma H28 cells. | 2010 | Phytother Res | pmid:20127663 |
| Kaup RM et al. | Antidiabetic effects of a standardized Egyptian rice bran extract. | 2013 | Phytother Res | pmid:22566008 |
| Yap WN et al. | In vivo evidence of gamma-tocotrienol as a chemosensitizer in the treatment of hormone-refractory prostate cancer. | 2010 | Pharmacology | pmid:20375535 |
| Makpol S et al. | Inhibition of mitochondrial cytochrome c release and suppression of caspases by gamma-tocotrienol prevent apoptosis and delay aging in stress-induced premature senescence of skin fibroblasts. | 2012 | Oxid Med Cell Longev | pmid:22919441 |
| Makpol S et al. | Gamma-tocotrienol modulated gene expression in senescent human diploid fibroblasts as revealed by microarray analysis. | 2013 | Oxid Med Cell Longev | pmid:23634235 |
| Makpol S et al. | gamma-Tocotrienol prevents oxidative stress-induced telomere shortening in human fibroblasts derived from different aged individuals. | 2010 Jan-Feb | Oxid Med Cell Longev | pmid:20716926 |
| Siveen KS et al. | Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model. | 2014 | Oncotarget | pmid:24722367 |
| Xu WL et al. | Inhibition of proliferation and induction of apoptosis by gamma-tocotrienol in human colon carcinoma HT-29 cells. | 2009 | Nutrition | pmid:19121919 |
| Yu W et al. | Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. | 1999 | Nutr Cancer | pmid:10227040 |
| Inoue A et al. | Induction of apoptosis by γ-tocotrienol in human cancer cell lines and leukemic blasts from patients: dependency on Bid, cytochrome c, and caspase pathway. | 2011 | Nutr Cancer | pmid:21660856 |
| Chang PN et al. | Evidence of gamma-tocotrienol as an apoptosis-inducing, invasion-suppressing, and chemotherapy drug-sensitizing agent in human melanoma cells. | 2009 | Nutr Cancer | pmid:19373609 |
| Zhao L et al. | Regulation of Obesity and Metabolic Complications by Gamma and Delta Tocotrienols. | 2016 | Molecules | pmid:26978344 |
| Yusof KM et al. | γ-Tocotrienol and 6-Gingerol in Combination Synergistically Induce Cytotoxicity and Apoptosis in HT-29 and SW837 Human Colorectal Cancer Cells. | 2015 | Molecules | pmid:26046324 |
| Ung CY et al. | In silico prediction of pregnane X receptor activators by machine learning approaches. | 2007 | Mol. Pharmacol. | pmid:17003167 |
| Kamat JP et al. | Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes. | 1997 | Mol. Cell. Biochem. | pmid:9144327 |
| Das S et al. | Tocotrienols confer resistance to ischemia in hypercholesterolemic hearts: insight with genomics. | 2012 | Mol. Cell. Biochem. | pmid:21918828 |
| Kannappan R et al. | Gamma-tocotrienol promotes TRAIL-induced apoptosis through reactive oxygen species/extracellular signal-regulated kinase/p53-mediated upregulation of death receptors. | 2010 | Mol. Cancer Ther. | pmid:20682650 |
| Gopalan A et al. | Involvement of de novo ceramide synthesis in gamma-tocopherol and gamma-tocotrienol-induced apoptosis in human breast cancer cells. | 2012 | Mol Nutr Food Res | pmid:23065795 |
| Xiong A et al. | Distinct roles of different forms of vitamin E in DHA-induced apoptosis in triple-negative breast cancer cells. | 2012 | Mol Nutr Food Res | pmid:22707267 |
| Matsunaga T et al. | γ-Tocotrienol attenuates TNF-α-induced changes in secretion and gene expression of MCP-1, IL-6 and adiponectin in 3T3-L1 adipocytes. | 2012 | Mol Med Rep | pmid:22293775 |
| Wong RS et al. | δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells. | 2012 | Microsc. Microanal. | pmid:22640960 |
| Rajikin MH et al. | Deleterious effects of nicotine on the ultrastructure of oocytes: role of gamma-tocotrienol. | 2009 | Med. Sci. Monit. | pmid:19946227 |
| Kamsani YS et al. | Nicotine-induced cessation of embryonic development is reversed by γ-tocotrienol in mice. | 2013 | Med Sci Monit Basic Res | pmid:23462735 |
| Deng L et al. | Tissue distribution of emulsified γ-tocotrienol and its long-term biological effects after subcutaneous administration. | 2014 | Lipids Health Dis | pmid:24712339 |
| Tsuzuki W et al. | Intestinal epithelial cells absorb gamma-tocotrienol faster than alpha-tocopherol. | 2007 | Lipids | pmid:17393222 |
| Wali VB and Sylvester PW | Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells. | 2007 | Lipids | pmid:17701065 |
| Uchida T et al. | Tissue distribution of α- and γ-tocotrienol and γ-tocopherol in rats and interference with their accumulation by α-tocopherol. | 2012 | Lipids | pmid:22042641 |
| Abuasal BS et al. | Enhancement of intestinal permeability utilizing solid lipid nanoparticles increases γ-tocotrienol oral bioavailability. | 2012 | Lipids | pmid:22271424 |
| Watkins T et al. | gamma-Tocotrienol as a hypocholesterolemic and antioxidant agent in rats fed atherogenic diets. | 1993 | Lipids | pmid:8121254 |
| Tomeo AC et al. | Antioxidant effects of tocotrienols in patients with hyperlipidemia and carotid stenosis. | 1995 | Lipids | pmid:8614310 |
| Nakagawa K et al. | gamma-Tocotrienol reduces squalene hydroperoxide-induced inflammatory responses in HaCaT keratinocytes. | 2010 | Lipids | pmid:20714817 |
| Wali VB et al. | Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment. | 2009 | Lipids | pmid:19777282 |