gamma-tocotrienol

Gamma-tocotrienol is a lipid of Prenol Lipids (PR) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 1076 references associated with gamma-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for gamma-tocotrienol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-tocotrienol

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Total 1

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with gamma-tocotrienol

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Authors Title Published Journal PubMed Link
Hermizi H et al. Beneficial effects of tocotrienol and tocopherol on bone histomorphometric parameters in sprague-dawley male rats after nicotine cessation. 2009 Calcif. Tissue Int. pmid:19020790
Xu WL et al. Inhibition of proliferation and induction of apoptosis by gamma-tocotrienol in human colon carcinoma HT-29 cells. 2009 Nutrition pmid:19121919
Berbée M et al. gamma-Tocotrienol ameliorates intestinal radiation injury and reduces vascular oxidative stress after total-body irradiation by an HMG-CoA reductase-dependent mechanism. 2009 Radiat. Res. pmid:19580495
Ghosh SP et al. Gamma-tocotrienol, a tocol antioxidant as a potent radioprotector. 2009 Int. J. Radiat. Biol. pmid:19557601
Rajikin MH et al. Deleterious effects of nicotine on the ultrastructure of oocytes: role of gamma-tocotrienol. 2009 Med. Sci. Monit. pmid:19946227
Sun W et al. gamma-Tocotrienol induces mitochondria-mediated apoptosis in human gastric adenocarcinoma SGC-7901 cells. 2009 J. Nutr. Biochem. pmid:18602811
Hiura Y et al. Specific accumulation of gamma- and delta-tocotrienols in tumor and their antitumor effect in vivo. 2009 J. Nutr. Biochem. pmid:18824342
Chang PN et al. Evidence of gamma-tocotrienol as an apoptosis-inducing, invasion-suppressing, and chemotherapy drug-sensitizing agent in human melanoma cells. 2009 Nutr Cancer pmid:19373609
Wali VB et al. Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment. 2009 Lipids pmid:19777282
Yap WN et al. In vivo evidence of gamma-tocotrienol as a chemosensitizer in the treatment of hormone-refractory prostate cancer. 2010 Pharmacology pmid:20375535
Abuasal B et al. Intestinal absorption of gamma-tocotrienol is mediated by Niemann-Pick C1-like 1: in situ rat intestinal perfusion studies. 2010 Drug Metab. Dispos. pmid:20207946
Bachawal SV et al. Combined gamma-tocotrienol and erlotinib/gefitinib treatment suppresses Stat and Akt signaling in murine mammary tumor cells. 2010 Anticancer Res. pmid:20332450
Bachawal SV et al. Enhanced antiproliferative and apoptotic response to combined treatment of gamma-tocotrienol with erlotinib or gefitinib in mammary tumor cells. 2010 BMC Cancer pmid:20211018
Zbierzak AM et al. Intersection of the tocopherol and plastoquinol metabolic pathways at the plastoglobule. 2010 Biochem. J. pmid:19843012
Samant GV et al. Anti-proliferative effects of gamma-tocotrienol on mammary tumour cells are associated with suppression of cell cycle progression. 2010 Cell Prolif. pmid:19922488
Yap WN et al. Id1, inhibitor of differentiation, is a key protein mediating anti-tumor responses of gamma-tocotrienol in breast cancer cells. 2010 Cancer Lett. pmid:19926394
Shirode AB and Sylvester PW Synergistic anticancer effects of combined gamma-tocotrienol and celecoxib treatment are associated with suppression in Akt and NFkappaB signaling. 2010 Biomed. Pharmacother. pmid:19954924
Shibata A et al. Suppression of gamma-tocotrienol on UVB induced inflammation in HaCaT keratinocytes and HR-1 hairless mice via inflammatory mediators multiple signaling. 2010 J. Agric. Food Chem. pmid:20465215
Kulkarni S et al. Hematological targets of radiation damage. 2010 Curr Drug Targets pmid:20583980
Kulkarni S et al. Gamma-tocotrienol protects hematopoietic stem and progenitor cells in mice after total-body irradiation. 2010 Radiat. Res. pmid:20518653
Nakashima K et al. The tocotrienol-rich fraction from rice bran enhances cisplatin-induced cytotoxicity in human mesothelioma H28 cells. 2010 Phytother Res pmid:20127663
Pierpaoli E et al. Gamma- and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression. 2010 Life Sci. pmid:20188744
Li F et al. Tocotrienol enriched palm oil prevents atherosclerosis through modulating the activities of peroxisome proliferators-activated receptors. 2010 Atherosclerosis pmid:20138624
Yang Z et al. Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. 2010 Int. J. Cancer pmid:19626588
Zaiden N et al. Gamma delta tocotrienols reduce hepatic triglyceride synthesis and VLDL secretion. 2010 J. Atheroscler. Thromb. pmid:20702976
Yap WN et al. Gamma- and delta-tocotrienols inhibit skin melanin synthesis by suppressing constitutive and UV-induced tyrosinase activation. 2010 Pigment Cell Melanoma Res pmid:20609176
Lekli I et al. Co-ordinated autophagy with resveratrol and γ-tocotrienol confers synergetic cardioprotection. 2010 J. Cell. Mol. Med. pmid:19799646
Nakagawa K et al. gamma-Tocotrienol reduces squalene hydroperoxide-induced inflammatory responses in HaCaT keratinocytes. 2010 Lipids pmid:20714817
Zainuddin A et al. Effect of experimental treatment on GAPDH mRNA expression as a housekeeping gene in human diploid fibroblasts. 2010 BMC Mol. Biol. pmid:20707929
Kannappan R et al. γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents. 2010 J. Biol. Chem. pmid:20720018
Kannappan R et al. Gamma-tocotrienol promotes TRAIL-induced apoptosis through reactive oxygen species/extracellular signal-regulated kinase/p53-mediated upregulation of death receptors. 2010 Mol. Cancer Ther. pmid:20682650
Hsieh TC et al. gamma-Tocotrienol controls proliferation, modulates expression of cell cycle regulatory proteins and up-regulates quinone reductase NQO2 in MCF-7 breast cancer cells. 2010 Anticancer Res. pmid:20683025
Mène-Saffrané L et al. Plastochromanol-8 and tocopherols are essential lipid-soluble antioxidants during seed desiccation and quiescence in Arabidopsis. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20837525
Kunnumakkara AB et al. {Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment. 2010 Cancer Res. pmid:20864511
Liu HK et al. Inhibitory effects of gamma-tocotrienol on invasion and metastasis of human gastric adenocarcinoma SGC-7901 cells. 2010 J. Nutr. Biochem. pmid:19195866
Shuid AN et al. Vitamin E exhibits bone anabolic actions in normal male rats. 2010 J. Bone Miner. Metab. pmid:19779668
Makpol S et al. gamma-Tocotrienol prevents oxidative stress-induced telomere shortening in human fibroblasts derived from different aged individuals. 2010 Jan-Feb Oxid Med Cell Longev pmid:20716926
Bi S et al. gamma-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line. 2010 Jul-Aug Toxicology pmid:20452389
Luk SU et al. Gamma-tocotrienol as an effective agent in targeting prostate cancer stem cell-like population. 2011 Int. J. Cancer pmid:20617516
Eugeni Piller L et al. Chloroplast lipid droplet type II NAD(P)H quinone oxidoreductase is essential for prenylquinone metabolism and vitamin K1 accumulation. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21844348
Wilankar C et al. Role of immunoregulatory transcription factors in differential immunomodulatory effects of tocotrienols. 2011 Free Radic. Biol. Med. pmid:21536125
Tan SW et al. Inhibitory effects of palm α-, γ- and δ-tocotrienol on lipopolysaccharide-induced nitric oxide production in BV2 microglia. 2011 Cell. Immunol. pmid:21839427
Uchida T et al. Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol. 2011 J. Nutr. Sci. Vitaminol. pmid:22293209
Ayoub NM et al. γ-Tocotrienol inhibits HGF-dependent mitogenesis and Met activation in highly malignant mammary tumour cells. 2011 Cell Prolif. pmid:21973114
Rajendran P et al. γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent. 2011 Br. J. Pharmacol. pmid:21198544
Brooks R et al. Direct inhibition of osteoclast formation and activity by the vitamin E isomer gamma-tocotrienol. 2011 Int J Vitam Nutr Res pmid:22673919
Abuasal B et al. Development and validation of a reversed-phase HPLC method for the determination of γ-tocotrienol in rat and human plasma. 2011 Biomed. Chromatogr. pmid:20734323
Inoue A et al. Induction of apoptosis by γ-tocotrienol in human cancer cell lines and leukemic blasts from patients: dependency on Bid, cytochrome c, and caspase pathway. 2011 Nutr Cancer pmid:21660856
Campbell SE et al. γ-Tocotrienol induces growth arrest through a novel pathway with TGFβ2 in prostate cancer. 2011 Free Radic. Biol. Med. pmid:21335085
Berbée M et al. Pentoxifylline enhances the radioprotective properties of γ-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems. 2011 Radiat. Res. pmid:21388273