gamma-tocotrienol

Gamma-tocotrienol is a lipid of Prenol Lipids (PR) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 1076 references associated with gamma-tocotrienol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for gamma-tocotrienol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-tocotrienol

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Total 1

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with gamma-tocotrienol

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Authors Title Published Journal PubMed Link
Kumar KS et al. Preferential radiation sensitization of prostate cancer in nude mice by nutraceutical antioxidant gamma-tocotrienol. 2006 Life Sci. pmid:16413038
Sakai M et al. Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells. 2006 J. Nutr. Biochem. pmid:16517139
Song BL and DeBose-Boyd RA Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols. 2006 J. Biol. Chem. pmid:16831864
Shah SJ and Sylvester PW Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity. 2005 Exp. Biol. Med. (Maywood) pmid:15792944
Shah SJ and Sylvester PW Tocotrienol-induced cytotoxicity is unrelated to mitochondrial stress apoptotic signaling in neoplastic mammary epithelial cells. 2005 Biochem. Cell Biol. pmid:15746970
Sylvester PW et al. Intracellular signaling mechanisms mediating the antiproliferative and apoptotic effects of gamma-tocotrienol in neoplastic mammary epithelial cells. 2005 J. Plant Physiol. pmid:16008108
Yap SP and Yuen KH Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations. 2004 Int J Pharm pmid:15288344
Conte C et al. Gamma-tocotrienol metabolism and antiproliferative effect in prostate cancer cells. 2004 Ann. N. Y. Acad. Sci. pmid:15753178
Zhou C et al. Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. 2004 Drug Metab. Dispos. pmid:15269186
Yap SP et al. Influence of route of administration on the absorption and disposition of alpha-, gamma- and delta-tocotrienols in rats. 2003 J. Pharm. Pharmacol. pmid:12625867
Fuchs J et al. HPLC analysis of vitamin E isoforms in human epidermis: correlation with minimal erythema dose and free radical scavenging activity. 2003 Free Radic. Biol. Med. pmid:12543248
Ikeda S et al. Dietary alpha-tocopherol decreases alpha-tocotrienol but not gamma-tocotrienol concentration in rats. 2003 J. Nutr. pmid:12566479
Saito H et al. Gamma-tocotrienol, a vitamin E homolog, is a natriuretic hormone precursor. 2003 J. Lipid Res. pmid:12730299
Newaz MA et al. Nitric oxide synthase activity in blood vessels of spontaneously hypertensive rats: antioxidant protection by gamma-tocotrienol. 2003 J. Physiol. Pharmacol. pmid:14566071
Mustad VA et al. Supplementation with 3 compositionally different tocotrienol supplements does not improve cardiovascular disease risk factors in men and women with hypercholesterolemia. 2002 Am. J. Clin. Nutr. pmid:12450888
Raederstorff D et al. Effect of either gamma-tocotrienol or a tocotrienol mixture on the plasma lipid profile in hamsters. 2002 Ann. Nutr. Metab. pmid:11914511
Qureshi AA et al. Novel tocotrienols of rice bran suppress cholesterogenesis in hereditary hypercholesterolemic swine. 2001 J. Nutr. pmid:11160537
Ikeda S et al. Dietary sesame seeds elevate alpha- and gamma-tocotrienol concentrations in skin and adipose tissue of rats fed the tocotrienol-rich fraction extracted from palm oil. 2001 J. Nutr. pmid:11694614
Sylvester PW et al. Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation. 2001 Cell Prolif. pmid:11736999
Nakamura H et al. Oral toxicity of a tocotrienol preparation in rats. 2001 Food Chem. Toxicol. pmid:11434987
Yap SP et al. Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status. 2001 J. Pharm. Pharmacol. pmid:11206194
Black TM et al. Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. 2000 J. Nutr. pmid:11015467
Goffman FD and Möllers C Changes in tocopherol and plastochromanol-8 contents in seeds and oil of oilseed rape (Brassica napus L.) during storage as influenced by temperature and air oxygen. 2000 J. Agric. Food Chem. pmid:10820066
Sen CK et al. Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells. 2000 J. Biol. Chem. pmid:10777609
Hattori A et al. Production of LLU-alpha following an oral administration of gamma-tocotrienol or gamma-tocopherol to rats. 2000 Biol. Pharm. Bull. pmid:11085376
Yu W et al. Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. 1999 Nutr Cancer pmid:10227040
Katsanidis E and Addis PB Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue. 1999 Free Radic. Biol. Med. pmid:10641704
Mo H and Elson CE Apoptosis and cell-cycle arrest in human and murine tumor cells are initiated by isoprenoids. 1999 J. Nutr. pmid:10203554
Theriault A et al. Effects of gamma-tocotrienol on ApoB synthesis, degradation, and secretion in HepG2 cells. 1999 Arterioscler. Thromb. Vasc. Biol. pmid:10073977
Newaz MA and Nawal NN Effect of gamma-tocotrienol on blood pressure, lipid peroxidation and total antioxidant status in spontaneously hypertensive rats (SHR). 1999 Clin. Exp. Hypertens. pmid:10574414
Wang Q et al. Effects of tocotrienol on the intracellular translocation and degradation of apolipoprotein B: possible involvement of a proteasome independent pathway. 1998 Biochem. Biophys. Res. Commun. pmid:9618265
Guthrie N et al. Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. 1997 J. Nutr. pmid:9082043
Kamat JP et al. Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes. 1997 Mol. Cell. Biochem. pmid:9144327
Makpol S et al. Different starting times of alpha-tocopherol and gamma-tocotrienol supplementation and tumor marker enzyme activities in the rat chemically induced with cancer. 1997 Gen. Pharmacol. pmid:9147029
He L et al. Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo. 1997 J. Nutr. pmid:9164984
Qureshi AA et al. Dietary alpha-tocopherol attenuates the impact of gamma-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickens. 1996 J. Nutr. pmid:8632210
Qureshi AA et al. Response of hypercholesterolemic subjects to administration of tocotrienols. 1995 Lipids pmid:8614309
Tomeo AC et al. Antioxidant effects of tocotrienols in patients with hyperlipidemia and carotid stenosis. 1995 Lipids pmid:8614310
Watkins T et al. gamma-Tocotrienol as a hypocholesterolemic and antioxidant agent in rats fed atherogenic diets. 1993 Lipids pmid:8121254
Parker RA et al. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. 1993 J. Biol. Chem. pmid:8388388
Ong FB et al. Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol. 1993 Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. pmid:7903615
Suarna C et al. Comparative antioxidant activity of tocotrienols and other natural lipid-soluble antioxidants in a homogeneous system, and in rat and human lipoproteins. 1993 Biochim. Biophys. Acta pmid:8443232
Qureshi AA et al. Lowering of serum cholesterol in hypercholesterolemic humans by tocotrienols (palmvitee). 1991 Am. J. Clin. Nutr. pmid:2012010
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