Gamma-tocopherol is a lipid of Prenol Lipids (PR) class. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Adverse effects, Longterm Effects, Luteal Phase and Drug Interactions. Gamma-tocopherol often locates in Blood. The related lipids are Total cholesterol.
To understand associated biological information of gamma-tocopherol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-tocopherol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenoma | D000236 | 40 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shamim AA et al. | Plasma zinc, vitamin B(12) and α-tocopherol are positively and plasma γ-tocopherol is negatively associated with Hb concentration in early pregnancy in north-west Bangladesh. | 2013 | Public Health Nutr | pmid:23469947 |
| Yuan L et al. | Glutathione S-transferase M1 and T1 gene polymorphisms with consumption of high fruit-juice and vegetable diet affect antioxidant capacity in healthy adults. | 2013 Jul-Aug | Nutrition | pmid:23422534 |
| Hernandez ML et al. | Vitamin E, γ-tocopherol, reduces airway neutrophil recruitment after inhaled endotoxin challenge in rats and in healthy volunteers. | 2013 | Free Radic. Biol. Med. | pmid:23402870 |
| Alipour M et al. | Safety and pharmacokinetic studies of liposomal antioxidant formulations containing N-acetylcysteine, α-tocopherol or γ-tocopherol in beagle dogs. | 2013 | Toxicol. Mech. Methods | pmid:23384394 |
| Prokopowicz A et al. | Effect of occupational lead exposure on α- and γ-tocopherol concentration in plasma. | 2013 | Occup Environ Med | pmid:23378446 |
| Mangialasche F et al. | Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol. | 2013 | J. Intern. Med. | pmid:23343471 |
| Müllner E et al. | Genome damage in peripheral blood lymphocytes of diabetic and non-diabetic individuals after intervention with vegetables and plant oil. | 2013 | Mutagenesis | pmid:23340810 |
| Tasanarong A et al. | New strategy of α- and γ-tocopherol to prevent contrast-induced acute kidney injury in chronic kidney disease patients undergoing elective coronary procedures. | 2013 | Nephrol. Dial. Transplant. | pmid:23314316 |
| Garaiova I et al. | Effect of a plant sterol, fish oil and B vitamin combination on cardiovascular risk factors in hypercholesterolemic children and adolescents: a pilot study. | 2013 | Nutr J | pmid:23297818 |
| Yang D et al. | Antioxidative activities of Ginkgo biloba extract on oil/water emulsion system prepared from an enzymatically modified lipid containing alpha-linolenic acid. | 2013 | J. Food Sci. | pmid:23278764 |
| Sánchez-Muniz FJ et al. | The antioxidant status response to low-fat and walnut paste-enriched meat differs in volunteers at high cardiovascular Risk carrying different PON-1 polymorphisms. | 2012 | J Am Coll Nutr | pmid:23204156 |
| Yang M et al. | Validation of an FFQ to assess short-term antioxidant intake against 30 d food records and plasma biomarkers. | 2014 | Public Health Nutr | pmid:23164175 |
| Vujasinović V et al. | Optimization of hull-less pumpkin seed roasting conditions using response surface methodology. | 2012 | J. Food Sci. | pmid:23163936 |
| Yamamoto Y et al. | γ-tocopherol nebulization decreases oxidative stress, arginase activity, and collagen deposition after burn and smoke inhalation in the ovine model. | 2012 | Shock | pmid:23160521 |
| Gopalan A et al. | Involvement of de novo ceramide synthesis in gamma-tocopherol and gamma-tocotrienol-induced apoptosis in human breast cancer cells. | 2012 | Mol Nutr Food Res | pmid:23065795 |
| Smolarek AK et al. | Dietary administration of δ- and γ-tocopherol inhibits tumorigenesis in the animal model of estrogen receptor-positive, but not HER-2 breast cancer. | 2012 | Cancer Prev Res (Phila) | pmid:22964476 |
| Hwang ES et al. | Effects of heat treatment on the carotenoid and tocopherol composition of tomato. | 2012 | J. Food Sci. | pmid:22950575 |
| Semchuk NM et al. | Effect of short-term salt stress on oxidative stress markers and antioxidant enzymes activity in tocopherol-deficient Arabidopsis thaliana plants. | 2012 Jul-Aug | Ukr Biokhim Zh (1999) | pmid:22946299 |
| Zia-Ul-Haq M et al. | Compositional study and antioxidant potential of Ipomoea hederacea Jacq. and Lepidium sativum L. seeds. | 2012 | Molecules | pmid:22932212 |
| Sanità di Toppi L et al. | A bifasic response to cadmium stress in carrot: Early acclimatory mechanisms give way to root collapse further to prolonged metal exposure. | 2012 | Plant Physiol. Biochem. | pmid:22868210 |
| Mah E et al. | Supplementation of a γ-tocopherol-rich mixture of tocopherols in healthy men protects against vascular endothelial dysfunction induced by postprandial hyperglycemia. | 2013 | J. Nutr. Biochem. | pmid:22841396 |
| Weinstein SJ et al. | Serum α-tocopherol and γ-tocopherol concentrations and prostate cancer risk in the PLCO Screening Trial: a nested case-control study. | 2012 | PLoS ONE | pmid:22792240 |
| Baumeister P et al. | Curcumin and other polyphenolic compounds in head and neck cancer chemoprevention. | 2012 | Oxid Med Cell Longev | pmid:22690273 |
| Nagao M et al. | Relation of serum α- and γ-tocopherol levels to cardiovascular disease-related mortality among Japanese men and women. | 2012 | J Epidemiol | pmid:22672959 |
| Veronezi CM and Jorge N | Bioactive compounds in lipid fractions of pumpkin (Cucurbita sp) seeds for use in food. | 2012 | J. Food Sci. | pmid:22671521 |
| Hofmann J et al. | Detecting functional groups of Arabidopsis mutants by metabolic profiling and evaluation of pleiotropic responses. | 2011 | Front Plant Sci | pmid:22639613 |
| Wang Y et al. | Plasma total antioxidant capacity is associated with dietary intake and plasma level of antioxidants in postmenopausal women. | 2012 | J. Nutr. Biochem. | pmid:22617460 |
| GarcÃa-Moreno MJ et al. | Genetic basis of unstable expression of high gamma-tocopherol content in sunflower seeds. | 2012 | BMC Plant Biol. | pmid:22607470 |
| Abuasal BS et al. | Comparison of the intestinal absorption and bioavailability of γ-tocotrienol and α-tocopherol: in vitro, in situ and in vivo studies. | 2012 | Biopharm Drug Dispos | pmid:22528033 |
| Martysiak-Żurowska D et al. | Concentrations of alpha- and gamma-tocopherols in human breast milk during the first months of lactation and in infant formulas. | 2013 | Matern Child Nutr | pmid:22513202 |
| González E et al. | Two by-products of the olive oil extraction industry as oleic acid supplement source for Iberian pigs: effect on the meat's chemical composition and induced lipoperoxidation. | 2012 | J. Sci. Food Agric. | pmid:22488674 |
| Bhutia Y et al. | Serum malondialdehyde level: Surrogate stress marker in the Sikkimese diabetics. | 2011 | J Nat Sci Biol Med | pmid:22470243 |
| Torricelli P et al. | γ-Tocopherol inhibits human prostate cancer cell proliferation by up-regulation of transglutaminase 2 and down-regulation of cyclins. | 2013 | Amino Acids | pmid:22460364 |
| Huang Y et al. | A γ-tocopherol-rich mixture of tocopherols maintains Nrf2 expression in prostate tumors of TRAMP mice via epigenetic inhibition of CpG methylation. | 2012 | J. Nutr. | pmid:22457388 |
| Blaylock RL and Maroon J | Natural plant products and extracts that reduce immunoexcitotoxicity-associated neurodegeneration and promote repair within the central nervous system. | 2012 | Surg Neurol Int | pmid:22439110 |
| Chen T et al. | Analytical characterization of Hempseed (seed of Cannabis sativa L.) oil from eight regions in China. | 2010 | J Diet Suppl | pmid:22435611 |
| Alipour M et al. | Acute toxicity study of liposomal antioxidant formulations containing N-acetylcysteine, α-tocopherol, and γ-tocopherol in rats. | 2012 | J Liposome Res | pmid:22401703 |
| Carter CJ | The Fox and the Rabbits-Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease. | 2011 | ISRN Neurol | pmid:22389816 |
| Smolarek AK et al. | Dietary tocopherols inhibit cell proliferation, regulate expression of ERα, PPARγ, and Nrf2, and decrease serum inflammatory markers during the development of mammary hyperplasia. | 2013 | Mol. Carcinog. | pmid:22389237 |
| Gawlik M et al. | The impact of Triton WR-1339 induced hyperlipidemia on the effects of benzo(a)pyrene or guaiacol on α- and γ-tocopherol pools and selected markers of pro-/antioxidative balance in rat plasma and erythrocytes. | 2012 | Environ. Toxicol. Pharmacol. | pmid:22387351 |
| Guan F et al. | δ- and γ-tocopherols, but not α-tocopherol, inhibit colon carcinogenesis in azoxymethane-treated F344 rats. | 2012 | Cancer Prev Res (Phila) | pmid:22366914 |
| Farré G et al. | Transgenic rice grains expressing a heterologous Ï-hydroxyphenylpyruvate dioxygenase shift tocopherol synthesis from the γ to the α isoform without increasing absolute tocopherol levels. | 2012 | Transgenic Res. | pmid:22361804 |
| Al-Bazi MM et al. | Reduced coenzyme Q(10) in female smokers and its association with lipid profile in a young healthy adult population. | 2011 | Arch Med Sci | pmid:22328876 |
| Andersson SC et al. | Tocopherols in rose hips (Rosa spp.) during ripening. | 2012 | J. Sci. Food Agric. | pmid:22311859 |
| López G and Galván M | [Relation of total cholesterol in serum tocopherols, probabilistic study in Mexican children]. | 2011 | Arch Latinoam Nutr | pmid:22308938 |
| Hamidi MS et al. | Effects of vitamin E on bone turnover markers among US postmenopausal women. | 2012 | J. Bone Miner. Res. | pmid:22308007 |
| Kim S et al. | Comparison of three tocopherol analogs as an inhibitor of production of proinflammatory mediators in macrophages. | 2012 | J. Pharmacol. Sci. | pmid:22302019 |
| Uchida T et al. | Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol. | 2011 | J. Nutr. Sci. Vitaminol. | pmid:22293209 |
| McCarty MF | Addendum: Gamma-tocopherol, cox-2, and cancer risk. | 2012 | Med. Hypotheses | pmid:22285625 |
| Chorell E et al. | Physical fitness level is reflected by alterations in the human plasma metabolome. | 2012 | Mol Biosyst | pmid:22282227 |