gamma-tocopherol

Gamma-tocopherol is a lipid of Prenol Lipids (PR) class. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Adverse effects, Longterm Effects, Luteal Phase and Drug Interactions. Gamma-tocopherol often locates in Blood. The related lipids are Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of gamma-tocopherol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-tocopherol?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-tocopherol

MeSH term MeSH ID Detail
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Adenoma D000236 40 associated lipids
Total 5

PubChem Associated disorders and diseases

What pathways are associated with gamma-tocopherol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-tocopherol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with gamma-tocopherol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-tocopherol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with gamma-tocopherol?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-tocopherol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-tocopherol

Download all related citations
Per page 10 20 50 100 | Total 818
Authors Title Published Journal PubMed Link
Abu-Amsha Caccetta R et al. Red wine polyphenols, in the absence of alcohol, reduce lipid peroxidative stress in smoking subjects. 2001 Free Radic. Biol. Med. pmid:11295361
Mukai K et al. Kinetic study of the quenching reaction of singlet oxygen by tea catechins in ethanol solution. 2005 Free Radic. Biol. Med. pmid:16109305
Li G et al. The antioxidant and anti-inflammatory activities of tocopherols are independent of Nrf2 in mice. 2012 Free Radic. Biol. Med. pmid:22226829
Fuchs J et al. HPLC analysis of vitamin E isoforms in human epidermis: correlation with minimal erythema dose and free radical scavenging activity. 2003 Free Radic. Biol. Med. pmid:12543248
Devaraj S et al. Gamma-tocopherol supplementation alone and in combination with alpha-tocopherol alters biomarkers of oxidative stress and inflammation in subjects with metabolic syndrome. 2008 Free Radic. Biol. Med. pmid:18191645
Wagner JG et al. Ozone enhancement of lower airway allergic inflammation is prevented by gamma-tocopherol. 2007 Free Radic. Biol. Med. pmid:17854713
Wiser J et al. In vivo gamma-tocopherol supplementation decreases systemic oxidative stress and cytokine responses of human monocytes in normal and asthmatic subjects. 2008 Free Radic. Biol. Med. pmid:18405673
Leonard SW et al. Studies in humans using deuterium-labeled alpha- and gamma-tocopherols demonstrate faster plasma gamma-tocopherol disappearance and greater gamma-metabolite production. 2005 Free Radic. Biol. Med. pmid:15749381
Wu JH et al. Nitration of gamma-tocopherol prevents its oxidative metabolism by HepG2 cells. 2005 Free Radic. Biol. Med. pmid:16043020
Kluth D et al. Modulation of Cyp3a11 mRNA expression by alpha-tocopherol but not gamma-tocotrienol in mice. 2005 Free Radic. Biol. Med. pmid:15649653
Bruno RS et al. Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation. 2006 Free Radic. Biol. Med. pmid:16458200
Hamahata A et al. gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury. 2008 Free Radic. Biol. Med. pmid:18503777
Hensley K et al. Measurement of 3-nitrotyrosine and 5-nitro-gamma-tocopherol by high-performance liquid chromatography with electrochemical detection. 2000 Free Radic. Biol. Med. pmid:10719233
Hensley K et al. New perspectives on vitamin E: gamma-tocopherol and carboxyelthylhydroxychroman metabolites in biology and medicine. 2004 Free Radic. Biol. Med. pmid:14732286
Botti H et al. Peroxynitrite-mediated alpha-tocopherol oxidation in low-density lipoprotein: a mechanistic approach. 2004 Free Radic. Biol. Med. pmid:14744627
Leonard SW et al. 5-nitro-gamma-tocopherol increases in human plasma exposed to cigarette smoke in vitro and in vivo. 2003 Free Radic. Biol. Med. pmid:14680679
Hernandez ML et al. Vitamin E, γ-tocopherol, reduces airway neutrophil recruitment after inhaled endotoxin challenge in rats and in healthy volunteers. 2013 Free Radic. Biol. Med. pmid:23402870
Wagner JG et al. Supplementation with γ-tocopherol attenuates endotoxin-induced airway neutrophil and mucous cell responses in rats. 2014 Free Radic. Biol. Med. pmid:24333275
Traber MG et al. Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets. 2005 Free Radic. Biol. Med. pmid:15721988
Barker T et al. Modulation of inflammation by vitamin E and C supplementation prior to anterior cruciate ligament surgery. 2009 Free Radic. Biol. Med. pmid:19111610
Quiles JL et al. Coenzyme Q concentration and total antioxidant capacity of human milk at different stages of lactation in mothers of preterm and full-term infants. 2006 Free Radic. Res. pmid:16390829
Minamiyama Y et al. Supplementation of alpha-tocopherol improves cardiovascular risk factors via the insulin signalling pathway and reduction of mitochondrial reactive oxygen species in type II diabetic rats. 2008 Free Radic. Res. pmid:18344121
Palm M et al. F(2)-isoprostanes, tocopherols and normal pregnancy. 2009 Free Radic. Res. pmid:19384749
Ishihara O et al. Isoprostanes, prostaglandins and tocopherols in pre-eclampsia, normal pregnancy and non-pregnancy. 2004 Free Radic. Res. pmid:15621708
Lyons NM et al. alpha-Tocopherol, but not gamma-tocopherol inhibits 7 beta-hydroxycholesterol-induced apoptosis in human U937 cells. 2001 Free Radic. Res. pmid:11697131
Fukui K et al. Changes in plasma alpha and gamma tocopherol levels before and after long-term local hyperthermia in cancer patients. 2006 Free Radic. Res. pmid:17015268
O'Leary KA et al. Gamma-tocopherol is less effective than alpha-tocopherol in preventing oxidant-induced sister chromatid exchanges in Chinese hamster V79 cells. 2001 Free Radic. Res. pmid:11811542
Pagano G et al. In vivo prooxidant state in Werner syndrome (WS): results from three WS patients and two WS heterozygotes. 2005 Free Radic. Res. pmid:16036329
Crohns M et al. Local and systemic oxidant/antioxidant status before and during lung cancer radiotherapy. 2009 Free Radic. Res. pmid:19444690
Galli F et al. gamma-Tocopherol biokinetics and transformation in humans. 2003 Free Radic. Res. pmid:14703735
Pei R et al. α-Tocopherol supplementation reduces 5-nitro-γ-tocopherol accumulation by decreasing γ-tocopherol in young adult smokers. 2015 Free Radic. Res. pmid:25966030
Hofmann J et al. Detecting functional groups of Arabidopsis mutants by metabolic profiling and evaluation of pleiotropic responses. 2011 Front Plant Sci pmid:22639613
Li CJ et al. Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNF-α) Induced Inflammatory Response in Bovine Cells. 2012 Gene Regul Syst Bio pmid:22267916
Li CJ et al. Alpha-Tocopherol Modulates Transcriptional Activities that Affect Essential Biological Processes in Bovine Cells. 2010 Gene Regul Syst Bio pmid:21157515
Tang YL et al. Molecular cloning and characterization of gene coding for γ-tocopherol methyltransferase from lettuce (Lactuca sativa). 2011 Genet. Mol. Res. pmid:22194177
Ipek M et al. Identification of molecular markers associated with fruit traits in olive and assessment of olive core collection with AFLP markers and fruit traits. 2015 Genet. Mol. Res. pmid:25867425
Palan PR et al. Lipid-soluble antioxidants and pregnancy: maternal serum levels of coenzyme Q10, alpha-tocopherol and gamma-tocopherol in preeclampsia and normal pregnancy. 2004 Gynecol. Obstet. Invest. pmid:14988604
Willett WC By the way, doctor. Is gamma-tocopherol a better form of vitamin E than alpha-tocopherol? 2003 Harv Health Lett pmid:12777226
Mannelli P et al. Opioid use affects antioxidant activity and purine metabolism: preliminary results. 2009 Hum Psychopharmacol pmid:19760630
Major JM et al. Genome-wide association study identifies common variants associated with circulating vitamin E levels. 2011 Hum. Mol. Genet. pmid:21729881
Pincemail J et al. Effect of different contraceptive methods on the oxidative stress status in women aged 40 48 years from the ELAN study in the province of Liege, Belgium. 2007 Hum. Reprod. pmid:17584753
Kadoma Y et al. Free radical interaction between vitamin E (alpha-, beta-, gamma- and delta-tocopherol), ascorbate and flavonoids. 2006 Nov-Dec In Vivo pmid:17203774
Hernandez M et al. Combination treatment with high-dose vitamin C and alpha-tocopherol does not enhance respiratory-tract lining fluid vitamin C levels in asthmatics. 2009 Inhal Toxicol pmid:18932058
Zou Y et al. Associations of serum retinol, α-tocopherol, and γ-tocopherol with biomarkers among healthy Japanese men. 2014 Int J Environ Res Public Health pmid:24487454
Sanches LD et al. Protective effect of γ-tocopherol-enriched diet on N-methyl-N-nitrosourea-induced epithelial dysplasia in rat ventral prostate. 2013 Int J Exp Pathol pmid:24205794
Ogita T et al. Identification and evaluation of antioxidants in Japanese parsley. 2016 Int J Food Sci Nutr pmid:27075296
Seker M et al. Screening and comparing tocopherols in the rapeseed (Brassica napus L.) and olive (Olea europaea L.) varieties using high-performance liquid chromatography. 2008 Int J Food Sci Nutr pmid:19086241
Li SY and Lo AC Lutein protects RGC-5 cells against hypoxia and oxidative stress. 2010 Int J Mol Sci pmid:20559505
Debbabi M et al. Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells. 2016 Int J Mol Sci pmid:27897980
Kuo F et al. Nanoemulsions of an anti-oxidant synergy formulation containing gamma tocopherol have enhanced bioavailability and anti-inflammatory properties. 2008 Int J Pharm pmid:18718513
Vuorimaa T et al. Acute prolonged exercise reduces moderately oxidized LDL in healthy men. Int J Sports Med pmid:16037882
Bates CJ et al. Plasma carotenoid and vitamin E concentrations in women living in a rural west African (Gambian) community. 2002 Int J Vitam Nutr Res pmid:12098880
Kaempf-Rotzoll DE et al. Influence of long-chain polyunsaturated fatty acid formula feeds on vitamin E status in preterm infants. 2003 Int J Vitam Nutr Res pmid:14639802
Illison VK et al. The relationship between plasma alpha-tocopherol concentration and vitamin E intake in patients with type 2 diabetes mellitus. 2011 Int J Vitam Nutr Res pmid:22002214
Elmadfa I and Wagner KH Non-nutritive bioactive food constituents of plants: tocopherols (vitamin E). 2003 Int J Vitam Nutr Res pmid:12747215
Steinhart H and Rathjen T Dependence of tocopherol stability on different cooking procedures of food. 2003 Int J Vitam Nutr Res pmid:12747222
Førli L et al. Vitamins A and E in serum in relation to weight and lung function in patients with advanced pulmonary disease. 2002 Int J Vitam Nutr Res pmid:12596500
Guidetti M et al. Vitamin A and vitamin E isoforms stability and peroxidation potential of all-in-one admixtures for parenteral nutrition. 2008 Int J Vitam Nutr Res pmid:19003738
Johansson C et al. Down-regulation of oxidative DNA lesions in human mononuclear cells after antioxidant supplementation correlates to increase of gamma-tocopherol. 2008 Jul-Sep Int J Vitam Nutr Res pmid:19326341
Giraud DW et al. Vitamin E inadequacy observed in a group of 2- to 6-year-old children living in Kwangju, Republic of Korea. 2008 Int J Vitam Nutr Res pmid:19003737
Djuric Z et al. Levels of fat-soluble micronutrients and 2,6-cyclolycopene-1,5-diol in head and neck cancer patients. 2007 Int J Vitam Nutr Res pmid:18622948
Salobir J et al. The comparison of black currant juice and vitamin E for the prevention of oxidative stress. 2010 Int J Vitam Nutr Res pmid:20533240
Chao PM et al. Conjugated linoleic acid causes a marked increase in liver alpha-tocopherol and liver alpha-tocopherol transfer protein in C57BL/6 J mice. 2010 Int J Vitam Nutr Res pmid:20533246
Elmadfa I et al. Selected quality parameters of salmon and meat when fried with or without added fat. 2006 Int J Vitam Nutr Res pmid:17243088
Aydemir O et al. Protective effects of vitamin E forms (alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate) on retinal edema during ischemia-reperfusion injury in the guinea pig retina. 2004 Oct-Dec Int Ophthalmol pmid:16532291
Mahabir S et al. Dietary alpha-, beta-, gamma- and delta-tocopherols in lung cancer risk. 2008 Int. J. Cancer pmid:18546288
Carman S et al. Vitamin E intake and risk of esophageal and gastric cancers in the NIH-AARP Diet and Health Study. 2009 Int. J. Cancer pmid:19326432
Barve A et al. Gamma-tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice. 2009 Int. J. Cancer pmid:19115203
Shin MJ et al. Effects of simvastatin on plasma antioxidant status and vitamins in hypercholesterolemic patients. 2007 Int. J. Cardiol. pmid:17005272
Chitarrini G et al. Buckwheat achenes antioxidant profile modulates Aspergillus flavus growth and aflatoxin production. 2014 Int. J. Food Microbiol. pmid:25108759
Oláh G et al. Cytoprotective effect of γ-tocopherol against tumor necrosis factor α induced cell dysfunction in L929 cells. 2011 Int. J. Mol. Med. pmid:21822532
Tanito M et al. Acceleration of age-related changes in the retina in alpha-tocopherol transfer protein null mice fed a Vitamin E-deficient diet. 2007 Invest. Ophthalmol. Vis. Sci. pmid:17197560
Cash WJ et al. Disordered vascular compliance in haemochromatosis. 2014 Ir J Med Sci pmid:24000100
Carter CJ The Fox and the Rabbits-Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease. 2011 ISRN Neurol pmid:22389816
Léger CL et al. First evidence for an LDL- and HDL-associated nitratase activity that denitrates albumin-bound nitrotyrosine--physiological consequences. 2008 IUBMB Life pmid:18379995
Chai W et al. Serum coenzyme Q₁₀, α-tocopherol, γ-tocopherol, and C-reactive protein levels and body mass index in adolescent and premenopausal females. 2014 J Am Coll Nutr pmid:24809382
Dietrich M et al. Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A review. 2006 J Am Coll Nutr pmid:16943450
Djuric Z et al. Effects of high fruit-vegetable and/or low-fat intervention on plasma micronutrient levels. 2006 J Am Coll Nutr pmid:16766775
Olmedilla-Alonso B et al. Consumption of restructured meat products with added walnuts has a cholesterol-lowering effect in subjects at high cardiovascular risk: a randomised, crossover, placebo-controlled study. 2008 J Am Coll Nutr pmid:18689569
Vatassery GT et al. Alpha and gamma tocopherols in cerebrospinal fluid and serum from older, male, human subjects. 2004 J Am Coll Nutr pmid:15190048
Sánchez-Muniz FJ et al. The antioxidant status response to low-fat and walnut paste-enriched meat differs in volunteers at high cardiovascular Risk carrying different PON-1 polymorphisms. 2012 J Am Coll Nutr pmid:23204156
Jambazian PR et al. Almonds in the diet simultaneously improve plasma alpha-tocopherol concentrations and reduce plasma lipids. 2005 J Am Diet Assoc pmid:15746835
Krishnan K et al. More optimal forms of vitamin E. 2005 J Am Diet Assoc pmid:15668675
Wiegand H et al. Dietary flavonoids do not affect vitamin E status in growing rats. 2010 J Anim Physiol Anim Nutr (Berl) pmid:19364372
O'Sullivan AJ et al. Toxicity of cholesterol oxidation products to Caco-2 and HepG2 cells: modulatory effects of alpha- and gamma-tocopherol. 2003 May-Jun J Appl Toxicol pmid:12794941
Zhang T et al. Antibacterial constituents from Stemona sessilifolia. J Asian Nat Prod Res pmid:17701569
Paromov V et al. Sulfur mustard toxicity following dermal exposure: role of oxidative stress, and antioxidant therapy. 2007 J Burns Wounds pmid:18091984
Ozten-KandaÅŸ N and Bosland MC Chemoprevention of prostate cancer: Natural compounds, antiandrogens, and antioxidants - In vivo evidence. 2011 J Carcinog pmid:22190869
Cheng J and Jandik P New type of microfabricated carbon electrodes for high-performance liquid chromatography--amperometric detection of fat-soluble vitamins and antioxidants. 2008 J Chromatogr A pmid:18538776
Chang LC et al. Cyclodextrin-modified microemulsion electrokinetic chromatography for separation of alpha-, gamma-, delta-tocopherol and alpha-tocopherol acetate. 2006 J Chromatogr A pmid:16457832
Sánchez-Machado DI et al. High-performance liquid chromatography method to measure alpha- and gamma-tocopherol in leaves, flowers and fresh beans from Moringa oleifera. 2006 J Chromatogr A pmid:16439255
Romeu-Nadal M et al. Determination of gamma- and alpha-tocopherols in human milk by a direct high-performance liquid chromatographic method with UV-vis detection and comparison with evaporative light scattering detection. 2006 J Chromatogr A pmid:16574129
Nagata Y et al. Products of the reaction between alpha- or gamma-tocopherol and nitrogen oxides analyzed by high-performance liquid chromatography with UV-visible and atmospheric pressure chemical ionization mass spectrometric detection. 2004 J Chromatogr A pmid:15146919
Xiao XH et al. Evaluation of vacuum microwave-assisted extraction technique for the extraction of antioxidants from plant samples. 2009 J Chromatogr A pmid:19922940
Yang WC et al. In vitro stable isotope labeling for discovery of novel metabolites by liquid chromatography-mass spectrometry: Confirmation of gamma-tocopherol metabolism in human A549 cell. 2010 J Chromatogr A pmid:20006340
Cauza E et al. Effects of LDL-immunoapheresis on plasma concentrations of vitamin E and carotenoids in patients with familial hypercholesterolemia. 2004 J Clin Apher pmid:15597350
Mehmetoglu I et al. Correlation between vitamin A, E, coenzyme Q(10) and degree of insulin resistance in obese and non-obese subjects. 2011 J Clin Biochem Nutr pmid:22128213
Park E et al. Susceptibility to Oxidative Stress is Greater in Korean Patients with Coronary Artery Disease than Healthy Subjects. 2009 J Clin Biochem Nutr pmid:19902026
Jin G et al. Coenzyme Q10-Binding/Transfer Protein Saposin B also Binds gamma-Tocopherol. 2008 J Clin Biochem Nutr pmid:18818759
Uto-Kondo H et al. gamma-Tocopherol Accelerated Sodium Excretion in a Dose-Dependent Manner in Rats with a High Sodium Intake. 2007 J Clin Biochem Nutr pmid:18299718