Gamma-tocopherol is a lipid of Prenol Lipids (PR) class. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Adverse effects, Longterm Effects, Luteal Phase and Drug Interactions. Gamma-tocopherol often locates in Blood. The related lipids are Total cholesterol.
To understand associated biological information of gamma-tocopherol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-tocopherol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:17725318 | ||||
| Key TJ et al. | Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study. | 2007 | Am. J. Clin. Nutr. | pmid:17823432 |
| McCarty MF | Gamma-tocopherol may promote effective no synthase function by protecting tetrahydrobiopterin from peroxynitrite. | 2007 | Med. Hypotheses | pmid:17825498 |
| pmid:17852477 | ||||
| Wagner JG et al. | Ozone enhancement of lower airway allergic inflammation is prevented by gamma-tocopherol. | 2007 | Free Radic. Biol. Med. | pmid:17854713 |
| pmid:17887802 | ||||
| Haug A et al. | Bovine milk in human nutrition--a review. | 2007 | Lipids Health Dis | pmid:17894873 |
| pmid:17927505 | ||||
| Uchida T et al. | Dietary sesame seed decreases urinary excretion of alpha- and gamma-tocopherol metabolites in rats. | 2007 | J. Nutr. Sci. Vitaminol. | pmid:17934245 |
| Webb AL et al. | Effect of vitamin supplementation on breast milk concentrations of retinol, carotenoids and tocopherols in HIV-infected Tanzanian women. | 2009 | Eur J Clin Nutr | pmid:17940544 |
| Wagner JG et al. | Gamma-tocopherol prevents airway eosinophilia and mucous cell hyperplasia in experimentally induced allergic rhinitis and asthma. | 2008 | Clin. Exp. Allergy | pmid:17970781 |
| Lee K et al. | Overexpression of Arabidopsis homogentisate phytyltransferase or tocopherol cyclase elevates vitamin E content by increasing gamma-tocopherol level in lettuce (Lactuca sativa L.). | 2007 | Mol. Cells | pmid:17978586 |
| pmid:17980889 | ||||
| pmid:17994356 | ||||
| Mohamed R et al. | Roselle (Hibiscus sabdariffa) seed oil is a rich source of gamma-tocopherol. | 2007 | J. Food Sci. | pmid:17995816 |
| Bloomer RJ | Decreased blood antioxidant capacity and increased lipid peroxidation in young cigarette smokers compared to nonsmokers: Impact of dietary intake. | 2007 | Nutr J | pmid:17996062 |
| Zigoneanu IG et al. | Determination of antioxidant components in rice bran oil extracted by microwave-assisted method. | 2008 | Bioresour. Technol. | pmid:17996444 |
| Kruk J and Trebst A | Plastoquinol as a singlet oxygen scavenger in photosystem II. | 2008 | Biochim. Biophys. Acta | pmid:18005659 |
| Yu W et al. | RRR-gamma-tocopherol induces human breast cancer cells to undergo apoptosis via death receptor 5 (DR5)-mediated apoptotic signaling. | 2008 | Cancer Lett. | pmid:18022315 |
| pmid:18023194 | ||||
| Turan S et al. | Fatty acid, triacylglycerol, phytosterol, and tocopherol variations in kernel oil of Malatya apricots from Turkey. | 2007 | J. Agric. Food Chem. | pmid:18038980 |
| Janson M | Orthomolecular medicine: the therapeutic use of dietary supplements for anti-aging. | 2006 | Clin Interv Aging | pmid:18046879 |
| pmid:18053685 | ||||
| pmid:18058795 | ||||
| Ikeda S et al. | Dietary sesame seed and its lignan increase both ascorbic acid concentration in some tissues and urinary excretion by stimulating biosynthesis in rats. | 2007 | J. Nutr. Sci. Vitaminol. | pmid:18079604 |
| Yamashita K et al. | Hydroxymatairesinol and sesaminol act differently on tocopherol concentrations in rats. | 2007 | J. Nutr. Sci. Vitaminol. | pmid:18079605 |
| Paromov V et al. | Sulfur mustard toxicity following dermal exposure: role of oxidative stress, and antioxidant therapy. | 2007 | J Burns Wounds | pmid:18091984 |
| pmid:18155317 | ||||
| Devaraj S et al. | Gamma-tocopherol supplementation alone and in combination with alpha-tocopherol alters biomarkers of oxidative stress and inflammation in subjects with metabolic syndrome. | 2008 | Free Radic. Biol. Med. | pmid:18191645 |
| Huebbe P et al. | Effect of apoE genotype and vitamin E on biomarkers of oxidative stress in cultured neuronal cells and the brain of targeted replacement mice. | 2007 | J. Physiol. Pharmacol. | pmid:18195481 |
| pmid:18198133 | ||||
| Luo M et al. | Metabolic effects of enteral versus parenteral alanyl-glutamine dipeptide administration in critically ill patients receiving enteral feeding: a pilot study. | 2008 | Clin Nutr | pmid:18258342 |
| pmid:18266792 | ||||
| Uto-Kondo H et al. | gamma-Tocopherol Accelerated Sodium Excretion in a Dose-Dependent Manner in Rats with a High Sodium Intake. | 2007 | J Clin Biochem Nutr | pmid:18299718 |
| Uusitalo L et al. | Serum alpha- and gamma-tocopherol concentrations and risk of advanced beta cell autoimmunity in children with HLA-conferred susceptibility to type 1 diabetes mellitus. | 2008 | Diabetologia | pmid:18317723 |
| pmid:18339681 | ||||
| Minamiyama Y et al. | Supplementation of alpha-tocopherol improves cardiovascular risk factors via the insulin signalling pathway and reduction of mitochondrial reactive oxygen species in type II diabetic rats. | 2008 | Free Radic. Res. | pmid:18344121 |
| Reiter E et al. | Enhanced anti-proliferative effects of combinatorial treatment of delta-tocopherol and resveratrol in human HMC-1 cells. | 2007 | Biofactors | pmid:18356579 |
| Léger CL et al. | First evidence for an LDL- and HDL-associated nitratase activity that denitrates albumin-bound nitrotyrosine--physiological consequences. | 2008 | IUBMB Life | pmid:18379995 |
| Wiser J et al. | In vivo gamma-tocopherol supplementation decreases systemic oxidative stress and cytokine responses of human monocytes in normal and asthmatic subjects. | 2008 | Free Radic. Biol. Med. | pmid:18405673 |
| Skorić D et al. | Genetic possibilities for altering sunflower oil quality to obtain novel oils. | 2008 | Can. J. Physiol. Pharmacol. | pmid:18418432 |
| Puri BK et al. | A comparison of oxidative stress in smokers and non-smokers: an in vivo human quantitative study of n-3 lipid peroxidation. | 2008 | BMC Psychiatry | pmid:18433514 |
| pmid:18436967 | ||||
| Kobayashi N and DellaPenna D | Tocopherol metabolism, oxidation and recycling under high light stress in Arabidopsis. | 2008 | Plant J. | pmid:18452591 |
| Spaccarotella KJ et al. | The effect of walnut intake on factors related to prostate and vascular health in older men. | 2008 | Nutr J | pmid:18454862 |
| pmid:18473816 | ||||
| Liang D et al. | Plasma vitamins E and A and risk of bladder cancer: a case-control analysis. | 2008 | Cancer Causes Control | pmid:18478342 |
| pmid:18484416 | ||||
| Park SK et al. | alpha- and gamma-Tocopherol prevent age-related transcriptional alterations in the heart and brain of mice. | 2008 | J. Nutr. | pmid:18492827 |
| Cavalca V et al. | Anesthetic propofol enhances plasma gamma-tocopherol levels in patients undergoing cardiac surgery. | 2008 | Anesthesiology | pmid:18497598 |
| Hamahata A et al. | gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury. | 2008 | Free Radic. Biol. Med. | pmid:18503777 |
| pmid:18513874 | ||||
| pmid:18538460 | ||||
| Cheng J and Jandik P | New type of microfabricated carbon electrodes for high-performance liquid chromatography--amperometric detection of fat-soluble vitamins and antioxidants. | 2008 | J Chromatogr A | pmid:18538776 |
| pmid:18541333 | ||||
| Frank J et al. | Sex differences in the inhibition of gamma-tocopherol metabolism by a single dose of dietary sesame oil in healthy subjects. | 2008 | Am. J. Clin. Nutr. | pmid:18541561 |
| Mahabir S et al. | Dietary alpha-, beta-, gamma- and delta-tocopherols in lung cancer risk. | 2008 | Int. J. Cancer | pmid:18546288 |
| Chaisuwan P et al. | Separation of alpha-, beta-, gamma-, delta-tocopherols and alpha-tocopherol acetate on a pentaerythritol diacrylate monostearate-ethylene dimethacrylate monolith by capillary electrochromatography. | 2008 | Electrophoresis | pmid:18548461 |
| Xu Z | Comparison of extraction methods for quantifying vitamin E from animal tissues. | 2008 | Bioresour. Technol. | pmid:18550368 |
| Murr C et al. | Inverse association between serum concentrations of neopterin and antioxidants in patients with and without angiographic coronary artery disease. | 2009 | Atherosclerosis | pmid:18556000 |
| Szymańska R and Kruk J | Gamma-tocopherol dominates in young leaves of runner bean (Phaseolus coccineus) under a variety of growing conditions: the possible functions of gamma-tocopherol. | 2008 | Phytochemistry | pmid:18582912 |
| pmid:18620402 | ||||
| Djuric Z et al. | Levels of fat-soluble micronutrients and 2,6-cyclolycopene-1,5-diol in head and neck cancer patients. | 2007 | Int J Vitam Nutr Res | pmid:18622948 |
| Ohnmacht S et al. | Inhibition of oxidative metabolism of tocopherols with omega-N-heterocyclic derivatives of vitamin E. | 2008 | Bioorg. Med. Chem. | pmid:18656365 |
| Borel P et al. | Human fasting plasma concentrations of vitamin E and carotenoids, and their association with genetic variants in apo C-III, cholesteryl ester transfer protein, hepatic lipase, intestinal fatty acid binding protein and microsomal triacylglycerol transfer protein. | 2009 | Br. J. Nutr. | pmid:18662427 |
| pmid:18670874 | ||||
| pmid:18677464 | ||||
| Olmedilla-Alonso B et al. | Consumption of restructured meat products with added walnuts has a cholesterol-lowering effect in subjects at high cardiovascular risk: a randomised, crossover, placebo-controlled study. | 2008 | J Am Coll Nutr | pmid:18689569 |
| Sacha B et al. | Heterogeneous effects of distinct tocopherol analogues on NO release, cell volume, and cell death in microglial cells. | 2008 | J. Neurosci. Res. | pmid:18709655 |
| Kuo F et al. | Nanoemulsions of an anti-oxidant synergy formulation containing gamma tocopherol have enhanced bioavailability and anti-inflammatory properties. | 2008 | Int J Pharm | pmid:18718513 |
| Spahis S et al. | Lipid profile, fatty acid composition and pro- and anti-oxidant status in pediatric patients with attention-deficit/hyperactivity disorder. | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18757191 | |
| Singh I et al. | Oxidative stress-induced insulin resistance in skeletal muscle cells is ameliorated by gamma-tocopherol treatment. | 2008 | Eur J Nutr | pmid:18807106 |
| Mourvaki E et al. | Distribution of alpha-, gamma (+beta)- and delta-tocopherol in the seminal plasma, spermatozoa and seminal vesicles of rabbit. | 2008 | Andrologia | pmid:18811917 |
| Jin G et al. | Coenzyme Q10-Binding/Transfer Protein Saposin B also Binds gamma-Tocopherol. | 2008 | J Clin Biochem Nutr | pmid:18818759 |
| Hernandez M et al. | Combination treatment with high-dose vitamin C and alpha-tocopherol does not enhance respiratory-tract lining fluid vitamin C levels in asthmatics. | 2009 | Inhal Toxicol | pmid:18932058 |
| pmid:18989718 | ||||
| Jiang Q et al. | A combination of aspirin and gamma-tocopherol is superior to that of aspirin and alpha-tocopherol in anti-inflammatory action and attenuation of aspirin-induced adverse effects. | 2009 | J. Nutr. Biochem. | pmid:18993050 |
| Cooney RV et al. | Elevated plasma gamma-tocopherol and decreased alpha-tocopherol in men are associated with inflammatory markers and decreased plasma 25-OH vitamin D. | 2008 | Nutr Cancer | pmid:19003577 |
| Giraud DW et al. | Vitamin E inadequacy observed in a group of 2- to 6-year-old children living in Kwangju, Republic of Korea. | 2008 | Int J Vitam Nutr Res | pmid:19003737 |
| Guidetti M et al. | Vitamin A and vitamin E isoforms stability and peroxidation potential of all-in-one admixtures for parenteral nutrition. | 2008 | Int J Vitam Nutr Res | pmid:19003738 |
| Ibrahim WH et al. | Effect of Ramadan fasting on markers of oxidative stress and serum biochemical markers of cellular damage in healthy subjects. | 2008 | Ann. Nutr. Metab. | pmid:19011280 |
| pmid:19012616 | ||||
| Hemilä H and Kaprio J | Vitamin E supplementation and pneumonia risk in males who initiated smoking at an early age: effect modification by body weight and dietary vitamin C. | 2008 | Nutr J | pmid:19019244 |
| Paliakov EM et al. | Rapid quantitative determination of fat-soluble vitamins and coenzyme Q-10 in human serum by reversed phase ultra-high pressure liquid chromatography with UV detection. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19041283 |
| Reboul E et al. | ATP-binding cassette transporter A1 is significantly involved in the intestinal absorption of alpha- and gamma-tocopherol but not in that of retinyl palmitate in mice. | 2009 | Am. J. Clin. Nutr. | pmid:19056557 |
| Allen NE et al. | Plasma selenium concentration and prostate cancer risk: results from the European Prospective Investigation into Cancer and Nutrition (EPIC). | 2008 | Am. J. Clin. Nutr. | pmid:19064517 |
| Zwart SR et al. | Effects of 21 days of bed rest, with or without artificial gravity, on nutritional status of humans. | 2009 | J. Appl. Physiol. | pmid:19074571 |
| Banerji R et al. | Oil and fatty acid diversity in genetically variable clones of Moringa oleifera from India. | 2009 | J Oleo Sci | pmid:19075502 |
| pmid:19079884 | ||||
| Yang H et al. | Preparation, characterization, and use of antioxidant-liposomes. | 2008 | Methods Mol. Biol. | pmid:19082954 |
| Seker M et al. | Screening and comparing tocopherols in the rapeseed (Brassica napus L.) and olive (Olea europaea L.) varieties using high-performance liquid chromatography. | 2008 | Int J Food Sci Nutr | pmid:19086241 |
| Yang J et al. | Antioxidant intervention of smoking-induced lung tumor in mice by vitamin E and quercetin. | 2008 | BMC Cancer | pmid:19099597 |
| Simpanya MF et al. | Expressed sequence tag analysis of guinea pig (Cavia porcellus) eye tissues for NEIBank. | 2008 | Mol. Vis. | pmid:19104676 |
| Barker T et al. | Modulation of inflammation by vitamin E and C supplementation prior to anterior cruciate ligament surgery. | 2009 | Free Radic. Biol. Med. | pmid:19111610 |
| Barve A et al. | Gamma-tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice. | 2009 | Int. J. Cancer | pmid:19115203 |
| Takahashi S et al. | Suppression of prostate cancer in a transgenic rat model via gamma-tocopherol activation of caspase signaling. | 2009 | Prostate | pmid:19143023 |
| Iughetti L et al. | Low-density lipoprotein oxidizability in children with chronic renal failure. | 2008 | Pediatr Int | pmid:19143965 |
| Ju J et al. | A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice. | 2009 | Cancer Prev Res (Phila) | pmid:19155443 |
| Gaedicke S et al. | Dietary vitamin E, brain redox status and expression of Alzheimer's disease-relevant genes in rats. | 2009 | Br. J. Nutr. | pmid:19173769 |
| Abreu ME and Munné-Bosch S | Salicylic acid deficiency in NahG transgenic lines and sid2 mutants increases seed yield in the annual plant Arabidopsis thaliana. | 2009 | J. Exp. Bot. | pmid:19188277 |