Gamma-tocopherol is a lipid of Prenol Lipids (PR) class. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Adverse effects, Longterm Effects, Luteal Phase and Drug Interactions. Gamma-tocopherol often locates in Blood. The related lipids are Total cholesterol.
To understand associated biological information of gamma-tocopherol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-tocopherol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kuo DC et al. | Partially hydrolyzed guar gum supplement reduces high-fat diet increased blood lipids and oxidative stress and ameliorates FeCl3-induced acute arterial injury in hamsters. | 2009 | J. Biomed. Sci. | pmid:19272178 |
| Polidori MC et al. | High fruit and vegetable intake is positively correlated with antioxidant status and cognitive performance in healthy subjects. | 2009 | J. Alzheimers Dis. | pmid:19542607 |
| Borel P et al. | Human fasting plasma concentrations of vitamin E and carotenoids, and their association with genetic variants in apo C-III, cholesteryl ester transfer protein, hepatic lipase, intestinal fatty acid binding protein and microsomal triacylglycerol transfer protein. | 2009 | Br. J. Nutr. | pmid:18662427 |
| Tlili N et al. | Carotenoid and tocopherol composition of leaves, buds, and flowers of Capparis spinosa grown wild in Tunisia. | 2009 | J. Agric. Food Chem. | pmid:19473002 |
| Shabtay A et al. | The potential of Pleurotus-treated olive mill solid waste as cattle feed. | 2009 | Bioresour. Technol. | pmid:19683915 |
| Jiang Q et al. | A combination of aspirin and gamma-tocopherol is superior to that of aspirin and alpha-tocopherol in anti-inflammatory action and attenuation of aspirin-induced adverse effects. | 2009 | J. Nutr. Biochem. | pmid:18993050 |
| Linden GJ et al. | Antioxidants and periodontitis in 60-70-year-old men. | 2009 | J. Clin. Periodontol. | pmid:19703237 |
| Krcmová L et al. | HPLC method for simultaneous determination of retinoids and tocopherols in human serum for monitoring of anticancer therapy. | 2009 | J Sep Sci | pmid:19606446 |
| Song SM et al. | [Concentrations of blood vitamin A, C, E, coenzyme Q10 and urine cotinine related to cigarette smoking exposure]. | 2009 | Korean J Lab Med | pmid:19262073 |
| Hemilä H and Kaprio J | Modification of the effect of vitamin E supplementation on the mortality of male smokers by age and dietary vitamin C. | 2009 | Am. J. Epidemiol. | pmid:19218294 |
| Abreu ME and Munné-Bosch S | Salicylic acid deficiency in NahG transgenic lines and sid2 mutants increases seed yield in the annual plant Arabidopsis thaliana. | 2009 | J. Exp. Bot. | pmid:19188277 |
| Zwart SR et al. | Effects of 21 days of bed rest, with or without artificial gravity, on nutritional status of humans. | 2009 | J. Appl. Physiol. | pmid:19074571 |
| Murr C et al. | Inverse association between serum concentrations of neopterin and antioxidants in patients with and without angiographic coronary artery disease. | 2009 | Atherosclerosis | pmid:18556000 |
| Gaedicke S et al. | Dietary vitamin E, brain redox status and expression of Alzheimer's disease-relevant genes in rats. | 2009 | Br. J. Nutr. | pmid:19173769 |
| Hernandez M et al. | Combination treatment with high-dose vitamin C and alpha-tocopherol does not enhance respiratory-tract lining fluid vitamin C levels in asthmatics. | 2009 | Inhal Toxicol | pmid:18932058 |
| Ju J et al. | A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice. | 2009 | Cancer Prev Res (Phila) | pmid:19155443 |
| Ney JG et al. | Associations of n-6 and n-3 polyunsaturated fatty acids and tocopherols with proxies of membrane stability and subcutaneous fat sites in male elite swimmers. | 2009 | Nutr Res | pmid:19854377 |
| Winter JL et al. | Antioxidant status and biomarkers of oxidative stress in dogs with lymphoma. | 2009 Mar-Apr | J. Vet. Intern. Med. | pmid:19210312 |
| Browne RW et al. | Follicular fluid high density lipoprotein-associated micronutrient levels are associated with embryo fragmentation during IVF. | 2009 Nov-Dec | J. Assist. Reprod. Genet. | pmid:19921421 |
| Kingsley M et al. | Role of creatine supplementation on exercise-induced cardiovascular function and oxidative stress. | 2009 Sep-Oct | Oxid Med Cell Longev | pmid:20716911 |
| Landrier JF et al. | Vitamin E decreases endogenous cholesterol synthesis and apo-AI-mediated cholesterol secretion in Caco-2 cells. | 2010 | J. Nutr. Biochem. | pmid:20149624 |
| Traber MG et al. | Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice. | 2010 | J. Nutr. Biochem. | pmid:20153623 |
| Chung MY et al. | Dietary α- and γ-tocopherol supplementation attenuates lipopolysaccharide-induced oxidative stress and inflammatory-related responses in an obese mouse model of nonalcoholic steatohepatitis. | 2010 | J. Nutr. Biochem. | pmid:20138495 |
| Traber MG | Regulation of xenobiotic metabolism, the only signaling function of alpha-tocopherol? | 2010 | Mol Nutr Food Res | pmid:20169584 |
| Maruti SS et al. | Dietary and demographic correlates of serum beta-glucuronidase activity. | 2010 | Nutr Cancer | pmid:20099195 |
| Lecea M et al. | Enantioselective total synthesis of the natural gamma-tocopherol metabolite (S)-gamma-CEHC [(S)-LLU-alpha]. | 2010 | Org. Lett. | pmid:20052974 |
| da Silveira CV et al. | Secondary plant substances in various extracts of the leaves, fruits, stem and bark of Caraipa densifolia Mart. | 2010 | Food Chem. Toxicol. | pmid:20347919 |
| Zbierzak AM et al. | Intersection of the tocopherol and plastoquinol metabolic pathways at the plastoglobule. | 2010 | Biochem. J. | pmid:19843012 |
| German JB and Dillard CJ | Saturated fats: a perspective from lactation and milk composition. | 2010 | Lipids | pmid:20652757 |
| Venkitaraman R et al. | Serum micronutrient and antioxidant levels at baseline and the natural history of men with localised prostate cancer on active surveillance. | 2010 | Tumour Biol. | pmid:20358422 |
| Gylling H et al. | The effect of a very high daily plant stanol ester intake on serum lipids, carotenoids, and fat-soluble vitamins. | 2010 | Clin Nutr | pmid:19709787 |
| Lindshield BL et al. | Selenium, but not lycopene or vitamin E, decreases growth of transplantable dunning R3327-H rat prostate tumors. | 2010 | PLoS ONE | pmid:20454690 |
| Saito F et al. | Reaction products of gamma-tocopherol with (E)-4-oxo-2-nonenal in acidic acetonitrile. | 2010 | Biosci. Biotechnol. Biochem. | pmid:20057122 |
| Wang S et al. | Temperature dependence of autoxidation of perilla oil and tocopherol degradation. | 2010 | J. Food Sci. | pmid:20722903 |
| Stenvinkel P | Inflammation as a target for improving health in chronic kidney disease. | 2010 | F1000 Med Rep | pmid:21283598 |
| Li CJ et al. | Alpha-Tocopherol Modulates Transcriptional Activities that Affect Essential Biological Processes in Bovine Cells. | 2010 | Gene Regul Syst Bio | pmid:21157515 |
| Peretti N et al. | Guidelines for the diagnosis and management of chylomicron retention disease based on a review of the literature and the experience of two centers. | 2010 | Orphanet J Rare Dis | pmid:20920215 |
| Bebrevska L et al. | In vivo antioxidative activity of a quantified Pueraria lobata root extract. | 2010 | J Ethnopharmacol | pmid:19799984 |
| Palan PR et al. | Effects of oral, vaginal, and transdermal hormonal contraception on serum levels of coenzyme q(10), vitamin e, and total antioxidant activity. | 2010 | Obstet Gynecol Int | pmid:20814444 |
| Colas R et al. | Increased lipid peroxidation in LDL from type-2 diabetic patients. | 2010 | Lipids | pmid:20703822 |
| Liu X et al. | Survivin gene silencing sensitizes prostate cancer cells to selenium growth inhibition. | 2010 | BMC Cancer | pmid:20698994 |
| Xi DM et al. | Seed-specific overexpression of antioxidant genes in Arabidopsis enhances oxidative stress tolerance during germination and early seedling growth. | 2010 | Plant Biotechnol. J. | pmid:20691023 |
| Schisterman EF et al. | Influence of endogenous reproductive hormones on F2-isoprostane levels in premenopausal women: the BioCycle Study. | 2010 | Am. J. Epidemiol. | pmid:20679069 |
| Kasimanickam RK et al. | Tocopherol induced angiogenesis in placental vascular network in late pregnant ewes. | 2010 | Reprod. Biol. Endocrinol. | pmid:20624307 |
| Meenakshisundaram R et al. | Risk factors for myocardial infarction among low socioeconomic status South Indian population. | 2010 | Diabetol Metab Syndr | pmid:20500893 |
| Beck K et al. | The effect of gold kiwifruit consumed with an iron fortified breakfast cereal meal on iron status in women with low iron stores: a 16 week randomised controlled intervention study. | 2010 | BMC Public Health | pmid:20102633 |
| Lu G et al. | A gamma-tocopherol-rich mixture of tocopherols inhibits chemically induced lung tumorigenesis in A/J mice and xenograft tumor growth. | 2010 | Carcinogenesis | pmid:20097733 |
| Rehkopf DH et al. | Differences in the association of cardiovascular risk factors with education: a comparison of Costa Rica (CRELES) and the USA (NHANES). | 2010 | J Epidemiol Community Health | pmid:19822554 |
| Ju J et al. | Cancer-preventive activities of tocopherols and tocotrienols. | 2010 | Carcinogenesis | pmid:19748925 |
| Ling TJ et al. | Antiseptic activity and phenolic constituents of the aerial parts of Vitex negundo var. cannabifolia. | 2010 | Molecules | pmid:21088661 |
| Heuberger AL et al. | Metabolomic and functional genomic analyses reveal varietal differences in bioactive compounds of cooked rice. | 2010 | PLoS ONE | pmid:20886119 |
| Tlili N et al. | Phenolic compounds and vitamin antioxidants of caper (Capparis spinosa). | 2010 | Plant Foods Hum Nutr | pmid:20668946 |
| Li SY and Lo AC | Lutein protects RGC-5 cells against hypoxia and oxidative stress. | 2010 | Int J Mol Sci | pmid:20559505 |
| Chen T et al. | Analytical characterization of Hempseed (seed of Cannabis sativa L.) oil from eight regions in China. | 2010 | J Diet Suppl | pmid:22435611 |
| Wiegand H et al. | Dietary flavonoids do not affect vitamin E status in growing rats. | 2010 | J Anim Physiol Anim Nutr (Berl) | pmid:19364372 |
| Kannappan R et al. | γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents. | 2010 | J. Biol. Chem. | pmid:20720018 |
| Wells SR et al. | Alpha-, gamma- and delta-tocopherols reduce inflammatory angiogenesis in human microvascular endothelial cells. | 2010 | J. Nutr. Biochem. | pmid:19443199 |
| Yang WC et al. | In vitro stable isotope labeling for discovery of novel metabolites by liquid chromatography-mass spectrometry: Confirmation of gamma-tocopherol metabolism in human A549 cell. | 2010 | J Chromatogr A | pmid:20006340 |
| Vucinic L et al. | Gamma tocopherol supplementation prevents exercise induced coagulation and platelet aggregation. | 2010 | Thromb. Res. | pmid:20004007 |
| Dodge HH et al. | Comparisons of plasma/serum micronutrients between Okinawan and Oregonian elders: a pilot study. | 2010 | J. Gerontol. A Biol. Sci. Med. Sci. | pmid:20643702 |
| Patel CJ et al. | An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus. | 2010 | PLoS ONE | pmid:20505766 |
| Salobir J et al. | The comparison of black currant juice and vitamin E for the prevention of oxidative stress. | 2010 | Int J Vitam Nutr Res | pmid:20533240 |
| Chao PM et al. | Conjugated linoleic acid causes a marked increase in liver alpha-tocopherol and liver alpha-tocopherol transfer protein in C57BL/6 J mice. | 2010 | Int J Vitam Nutr Res | pmid:20533246 |
| Chai W et al. | Associations between obesity and serum lipid-soluble micronutrients among premenopausal women. | 2010 | Nutr Res | pmid:20534324 |
| Guseva DA et al. | [Antioxidant activity of vegetable oils with various omega-6/omega-3 fatty acids ratio]. | 2010 May-Jun | Biomed Khim | pmid:20695213 |
| Sussmann RA et al. | Intraerythrocytic stages of Plasmodium falciparum biosynthesize vitamin E. | 2011 | FEBS Lett. | pmid:22085796 |
| Cheng TY et al. | Genetic variation in myeloperoxidase modifies the association of serum α-tocopherol with aggressive prostate cancer among current smokers. | 2011 | J. Nutr. | pmid:21795425 |
| Fernandes A et al. | Assessing the effects of gamma irradiation and storage time in energetic value and in major individual nutrients of chestnuts. | 2011 | Food Chem. Toxicol. | pmid:21740949 |
| Oláh G et al. | Cytoprotective effect of γ-tocopherol against tumor necrosis factor α induced cell dysfunction in L929 cells. | 2011 | Int. J. Mol. Med. | pmid:21822532 |
| Al-Bazi MM et al. | Reduced coenzyme Q(10) in female smokers and its association with lipid profile in a young healthy adult population. | 2011 | Arch Med Sci | pmid:22328876 |
| Kasimanickam RK and Kasimanickam VR | Effect of tocopherol supplementation on serum 8-epi-prostaglandin F2 alpha and adiponectin concentrations, and mRNA expression of PPARγ and related genes in ovine placenta and uterus. | 2011 | Theriogenology | pmid:21550107 |
| Uchida T et al. | Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol. | 2011 | J. Nutr. Sci. Vitaminol. | pmid:22293209 |
| Illison VK et al. | The relationship between plasma alpha-tocopherol concentration and vitamin E intake in patients with type 2 diabetes mellitus. | 2011 | Int J Vitam Nutr Res | pmid:22002214 |
| Abdollahzadeh Sh et al. | Antibacterial and antifungal activities of punica granatum peel extracts against oral pathogens. | 2011 | J Dent (Tehran) | pmid:21998800 |
| Kashinakunti SV et al. | Comparative study of serum MDA and vitamin C levels in non-smokers, chronic smokers and chronic smokers with acute myocardial infarction in men. | 2011 | J Res Med Sci | pmid:22279473 |
| Yang R et al. | Antioxidant effect of a marine oligopeptide preparation from chum salmon (Oncorhynchus keta) by enzymatic hydrolysis in radiation injured mice. | 2011 | Mar Drugs | pmid:22163188 |
| Mehmetoglu I et al. | Correlation between vitamin A, E, coenzyme Q(10) and degree of insulin resistance in obese and non-obese subjects. | 2011 | J Clin Biochem Nutr | pmid:22128213 |
| Major JM et al. | Genome-wide association study identifies common variants associated with circulating vitamin E levels. | 2011 | Hum. Mol. Genet. | pmid:21729881 |
| Comhair SA et al. | Detrimental effects of environmental tobacco smoke in relation to asthma severity. | 2011 | PLoS ONE | pmid:21572527 |
| Qureshi AA et al. | Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries. | 2011 | Lipids Health Dis | pmid:21489303 |
| Odegaard AO et al. | Dietary patterns and incident type 2 diabetes in chinese men and women: the singapore chinese health study. | 2011 | Diabetes Care | pmid:21330641 |
| Hodge A et al. | Plasma carotenoids are associated with socioeconomic status in an urban Indigenous population: an observational study. | 2011 | BMC Public Health | pmid:21288365 |
| Hofmann J et al. | Detecting functional groups of Arabidopsis mutants by metabolic profiling and evaluation of pleiotropic responses. | 2011 | Front Plant Sci | pmid:22639613 |
| Bhutia Y et al. | Serum malondialdehyde level: Surrogate stress marker in the Sikkimese diabetics. | 2011 | J Nat Sci Biol Med | pmid:22470243 |
| Carter CJ | The Fox and the Rabbits-Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease. | 2011 | ISRN Neurol | pmid:22389816 |
| Trattner S et al. | Influence of dietary sesamin, a bioactive compound on fatty acids and expression of some lipid regulating genes in Baltic Atlantic salmon (Salmo salar L.) juveniles. | 2011 | Physiol Res | pmid:20945950 |
| Giles LV et al. | From good intentions to proven interventions: effectiveness of actions to reduce the health impacts of air pollution. | 2011 | Environ. Health Perspect. | pmid:20729178 |
| López G and Galván M | [Relation of total cholesterol in serum tocopherols, probabilistic study in Mexican children]. | 2011 | Arch Latinoam Nutr | pmid:22308938 |
| Smolarek AK and Suh N | Chemopreventive activity of vitamin E in breast cancer: a focus on γ- and δ-tocopherol. | 2011 | Nutrients | pmid:22254089 |
| Ozten-KandaÅŸ N and Bosland MC | Chemoprevention of prostate cancer: Natural compounds, antiandrogens, and antioxidants - In vivo evidence. | 2011 | J Carcinog | pmid:22190869 |
| Tang YL et al. | Molecular cloning and characterization of gene coding for γ-tocopherol methyltransferase from lettuce (Lactuca sativa). | 2011 | Genet. Mol. Res. | pmid:22194177 |
| Li GX et al. | δ-tocopherol is more active than α - or γ -tocopherol in inhibiting lung tumorigenesis in vivo. | 2011 | Cancer Prev Res (Phila) | pmid:21372040 |
| McCary CA et al. | Supplemental and highly elevated tocopherol doses differentially regulate allergic inflammation: reversibility of α-tocopherol and γ-tocopherol's effects. | 2011 | J. Immunol. | pmid:21317387 |
| Ouyang S et al. | The role of tocopherol cyclase in salt stress tolerance of rice (Oryza sativa). | 2011 | Sci China Life Sci | pmid:21318489 |
| D'Adamo CR et al. | Serum vitamin E concentrations among highly functioning hip fracture patients are higher than in nonfracture controls. | 2011 | Nutr Res | pmid:21481714 |
| Joo JC et al. | Effects of puffer (Sphoeroides rubripes) supplementation on disruption of antioxidant defense systems in ethanol-treated rats. | 2011 | J. Nutr. Sci. Vitaminol. | pmid:21512295 |
| Kim JS et al. | Phytochemicals and antioxidant activity of fruits and leaves of paprika (Capsicum Annuum L., var. special) cultivated in Korea. | 2011 | J. Food Sci. | pmid:21535734 |
| Cela J et al. | Accumulation of γ- rather than α-tocopherol alters ethylene signaling gene expression in the vte4 mutant of Arabidopsis thaliana. | 2011 | Plant Cell Physiol. | pmid:21719428 |
| Petraglia AL et al. | Stuck at the bench: Potential natural neuroprotective compounds for concussion. | 2011 | Surg Neurol Int | pmid:22059141 |
| Naqvi S et al. | Simultaneous expression of Arabidopsis Ï-hydroxyphenylpyruvate dioxygenase and MPBQ methyltransferase in transgenic corn kernels triples the tocopherol content. | 2011 | Transgenic Res. | pmid:20401738 |