Gamma-tocopherol is a lipid of Prenol Lipids (PR) class. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Adverse effects, Longterm Effects, Luteal Phase and Drug Interactions. Gamma-tocopherol often locates in Blood. The related lipids are Total cholesterol.
To understand associated biological information of gamma-tocopherol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-tocopherol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Uchida T et al. | Dietary sesame seed decreases urinary excretion of alpha- and gamma-tocopherol metabolites in rats. | 2007 | J. Nutr. Sci. Vitaminol. | pmid:17934245 |
| Lee K et al. | Overexpression of Arabidopsis homogentisate phytyltransferase or tocopherol cyclase elevates vitamin E content by increasing gamma-tocopherol level in lettuce (Lactuca sativa L.). | 2007 | Mol. Cells | pmid:17978586 |
| Abbasi AR et al. | Specific roles of alpha- and gamma-tocopherol in abiotic stress responses of transgenic tobacco. | 2007 | Plant Physiol. | pmid:17293434 |
| Li L et al. | Fatty acid profiles, tocopherol contents, and antioxidant activities of heartnut (Juglans ailanthifolia Var. cordiformis) and Persian walnut (Juglans regia L.). | 2007 | J. Agric. Food Chem. | pmid:17253708 |
| Nguyen Q and Southwell-Keely PT | Reaction of gamma-tocopherol with hypochlorous acid. | 2007 | Lipids | pmid:17393223 |
| Pincemail J et al. | Effect of different contraceptive methods on the oxidative stress status in women aged 40 48 years from the ELAN study in the province of Liege, Belgium. | 2007 | Hum. Reprod. | pmid:17584753 |
| Reiter E et al. | Enhanced anti-proliferative effects of combinatorial treatment of delta-tocopherol and resveratrol in human HMC-1 cells. | 2007 | Biofactors | pmid:18356579 |
| Parker RS | A recent brief critical review on how an increased intake of alpha-tocopherol can suppress the bioavailability of gamma-tocopher. | 2007 | Nutr. Rev. | pmid:17425066 |
| Cheng WY et al. | Isolation and identification of novel estrogenic compounds in yam tuber (Dioscorea alata Cv. Tainung No. 2). | 2007 | J. Agric. Food Chem. | pmid:17685543 |
| Jham GN et al. | Gamma-tocopherol as a marker of Brazilian coffee (Coffea arabica L.) adulteration by corn. | 2007 | J. Agric. Food Chem. | pmid:17602658 |
| Desel C et al. | Nitration of gamma-tocopherol in plant tissues. | 2007 | Planta | pmid:17619201 |
| Let MB et al. | Ascorbyl palmitate, gamma-tocopherol, and EDTA affect lipid oxidation in fish oil enriched salad dressing differently. | 2007 | J. Agric. Food Chem. | pmid:17319681 |
| Ikeda S et al. | Dietary sesame seed and its lignan increase both ascorbic acid concentration in some tissues and urinary excretion by stimulating biosynthesis in rats. | 2007 | J. Nutr. Sci. Vitaminol. | pmid:18079604 |
| Yamashita K et al. | Hydroxymatairesinol and sesaminol act differently on tocopherol concentrations in rats. | 2007 | J. Nutr. Sci. Vitaminol. | pmid:18079605 |
| Mohamed R et al. | Roselle (Hibiscus sabdariffa) seed oil is a rich source of gamma-tocopherol. | 2007 | J. Food Sci. | pmid:17995816 |
| Huebbe P et al. | Effect of apoE genotype and vitamin E on biomarkers of oxidative stress in cultured neuronal cells and the brain of targeted replacement mice. | 2007 | J. Physiol. Pharmacol. | pmid:18195481 |
| Wagner JG et al. | Ozone enhancement of lower airway allergic inflammation is prevented by gamma-tocopherol. | 2007 | Free Radic. Biol. Med. | pmid:17854713 |
| Singh I et al. | Effects of gamma-tocopherol supplementation on thrombotic risk factors. | 2007 | Asia Pac J Clin Nutr | pmid:17704022 |
| Ahn KS et al. | Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis. | 2007 | J. Biol. Chem. | pmid:17114179 |
| McCarty MF | Gamma-tocopherol may promote effective no synthase function by protecting tetrahydrobiopterin from peroxynitrite. | 2007 | Med. Hypotheses | pmid:17825498 |
| Abe C et al. | Triton WR1339, an inhibitor of lipoprotein lipase, decreases vitamin E concentration in some tissues of rats by inhibiting its transport to liver. | 2007 | J. Nutr. | pmid:17237309 |
| Tanito M et al. | Acceleration of age-related changes in the retina in alpha-tocopherol transfer protein null mice fed a Vitamin E-deficient diet. | 2007 | Invest. Ophthalmol. Vis. Sci. | pmid:17197560 |
| Hermans N et al. | Study of potential systemic oxidative stress animal models for the evaluation of antioxidant activity: status of lipid peroxidation and fat-soluble antioxidants. | 2007 | J. Pharm. Pharmacol. | pmid:17227630 |
| Werba JP et al. | A new compound-specific pleiotropic effect of statins: modification of plasma gamma-tocopherol levels. | 2007 | Atherosclerosis | pmid:16860808 |
| Ward NC et al. | The effect of vitamin E on blood pressure in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled trial. | 2007 | J. Hypertens. | pmid:17143195 |
| Zou S et al. | Comparative approaches to facilitate the discovery of prolongevity interventions: effects of tocopherols on lifespan of three invertebrate species. | 2007 | Mech. Ageing Dev. | pmid:17169403 |
| Paromov V et al. | Sulfur mustard toxicity following dermal exposure: role of oxidative stress, and antioxidant therapy. | 2007 | J Burns Wounds | pmid:18091984 |
| Wilson TA et al. | Rice bran oil and oryzanol reduce plasma lipid and lipoprotein cholesterol concentrations and aortic cholesterol ester accumulation to a greater extent than ferulic acid in hypercholesterolemic hamsters. | 2007 | J. Nutr. Biochem. | pmid:16713234 |
| Turan S et al. | Fatty acid, triacylglycerol, phytosterol, and tocopherol variations in kernel oil of Malatya apricots from Turkey. | 2007 | J. Agric. Food Chem. | pmid:18038980 |
| Haug A et al. | Bovine milk in human nutrition--a review. | 2007 | Lipids Health Dis | pmid:17894873 |
| Papas K et al. | Bioavailability of a novel, water-soluble vitamin E formulation in malabsorbing patients. | 2007 | Dig. Dis. Sci. | pmid:17216337 |
| Gentile C et al. | Antioxidant activity of Sicilian pistachio (Pistacia vera L. var. Bronte) nut extract and its bioactive components. | 2007 | J. Agric. Food Chem. | pmid:17263455 |
| Shin MJ et al. | Effects of simvastatin on plasma antioxidant status and vitamins in hypercholesterolemic patients. | 2007 | Int. J. Cardiol. | pmid:17005272 |
| Uto-Kondo H et al. | gamma-Tocopherol Accelerated Sodium Excretion in a Dose-Dependent Manner in Rats with a High Sodium Intake. | 2007 | J Clin Biochem Nutr | pmid:18299718 |
| Bloomer RJ | Decreased blood antioxidant capacity and increased lipid peroxidation in young cigarette smokers compared to nonsmokers: Impact of dietary intake. | 2007 | Nutr J | pmid:17996062 |
| Voll LM and Abbasi AR | Are there Specific In Vivo Roles for alpha- and gamma-Tocopherol in Plants? | 2007 | Plant Signal Behav | pmid:19704593 |
| Himmelfarb J et al. | Gamma-tocopherol and docosahexaenoic acid decrease inflammation in dialysis patients. | 2007 | J Ren Nutr | pmid:17720098 |
| Key TJ et al. | Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study. | 2007 | Am. J. Clin. Nutr. | pmid:17823432 |
| Sundl I et al. | Increased concentrations of circulating vitamin E in carriers of the apolipoprotein A5 gene - 1131T>C variant and associations with plasma lipids and lipid peroxidation. | 2007 | J. Lipid Res. | pmid:17693622 |
| Sen CK et al. | Tocotrienols: the emerging face of natural vitamin E. | 2007 | Vitam. Horm. | pmid:17628176 |
| Tanaka Y et al. | Enhancement of intracellular gamma-tocopherol levels in cytokine-stimulated C3H 10T1/2 fibroblasts: relation to NO synthesis, isoprostane formation, and tocopherol oxidation. | 2007 | BMC Chem Biol | pmid:17608946 |
| Wright ME et al. | Supplemental and dietary vitamin E intakes and risk of prostate cancer in a large prospective study. | 2007 | Cancer Epidemiol. Biomarkers Prev. | pmid:17548674 |
| Siluk D et al. | A validated liquid chromatography method for the simultaneous determination of vitamins A and E in human plasma. | 2007 | J Pharm Biomed Anal | pmid:17499473 |
| Takemoto K et al. | Biochemical characterization of reactive nitrogen species by eosinophil peroxidase in tyrosine nitration. | 2007 | Acta Med. Okayama | pmid:17332838 |
| Winterbone MS et al. | Pro-oxidant effect of alpha-tocopherol in patients with type 2 diabetes after an oral glucose tolerance test--a randomised controlled trial. | 2007 | Cardiovasc Diabetol | pmid:17316429 |
| Jiang Q et al. | Identification and quantitation of novel vitamin E metabolites, sulfated long-chain carboxychromanols, in human A549 cells and in rats. | 2007 | J. Lipid Res. | pmid:17299205 |
| Wu JH et al. | Effects of alpha-tocopherol and mixed tocopherol supplementation on markers of oxidative stress and inflammation in type 2 diabetes. | 2007 | Clin. Chem. | pmid:17272491 |
| Lim Y and Traber MG | Alpha-Tocopherol Transfer Protein (alpha-TTP): Insights from Alpha-Tocopherol Transfer Protein Knockout Mice. | 2007 | Nutr Res Pract | pmid:20368946 |
| Mishina TE et al. | Expression of a nitric oxide degrading enzyme induces a senescence programme in Arabidopsis. | 2007 | Plant Cell Environ. | pmid:17177875 |
| Djuric Z et al. | Levels of fat-soluble micronutrients and 2,6-cyclolycopene-1,5-diol in head and neck cancer patients. | 2007 | Int J Vitam Nutr Res | pmid:18622948 |
| Freeman LM et al. | Effects of dietary modification in dogs with early chronic valvular disease. | 2006 Sep-Oct | J. Vet. Intern. Med. | pmid:17063703 |
| Kadoma Y et al. | Free radical interaction between vitamin E (alpha-, beta-, gamma- and delta-tocopherol), ascorbate and flavonoids. | 2006 Nov-Dec | In Vivo | pmid:17203774 |
| Szołtysek-Bołdys I et al. | [The influence of smoking on plasma non-enzymatic antioxidant concentrations in active smokers (preliminary report)]. | 2006 | Prz. Lek. | pmid:17288194 |
| Peñalvo JL et al. | Effect of sesamin on serum cholesterol and triglycerides levels in LDL receptor-deficient mice. | 2006 | Eur J Nutr | pmid:17039285 |
| Quiles JL et al. | Coenzyme Q concentration and total antioxidant capacity of human milk at different stages of lactation in mothers of preterm and full-term infants. | 2006 | Free Radic. Res. | pmid:16390829 |
| Ewen JG et al. | Influences of carotenoid supplementation on the integrated antioxidant system of a free living endangered passerine, the hihi (Notiomystis cincta). | 2006 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:16406271 |
| Reboul E et al. | Scavenger receptor class B type I (SR-BI) is involved in vitamin E transport across the enterocyte. | 2006 | J. Biol. Chem. | pmid:16380385 |
| Clarke MW et al. | Supplementation with mixed tocopherols increases serum and blood cell gamma-tocopherol but does not alter biomarkers of platelet activation in subjects with type 2 diabetes. | 2006 | Am. J. Clin. Nutr. | pmid:16400056 |
| Thane CW et al. | Plasma phylloquinone (vitamin K1) concentration and its relationship to intake in British adults aged 19-64 years. | 2006 | Br. J. Nutr. | pmid:17181887 |
| Janson M | Orthomolecular medicine: the therapeutic use of dietary supplements for anti-aging. | 2006 | Clin Interv Aging | pmid:18046879 |
| Chang LC et al. | Cyclodextrin-modified microemulsion electrokinetic chromatography for separation of alpha-, gamma-, delta-tocopherol and alpha-tocopherol acetate. | 2006 | J Chromatogr A | pmid:16457832 |
| Bruno RS et al. | Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation. | 2006 | Free Radic. Biol. Med. | pmid:16458200 |
| Sánchez-Machado DI et al. | High-performance liquid chromatography method to measure alpha- and gamma-tocopherol in leaves, flowers and fresh beans from Moringa oleifera. | 2006 | J Chromatogr A | pmid:16439255 |
| Samandari E et al. | The effect of gamma-tocopherol on proliferation, integrin expression, adhesion, and migration of human glioma cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16516856 |
| Fukui K et al. | Changes in plasma alpha and gamma tocopherol levels before and after long-term local hyperthermia in cancer patients. | 2006 | Free Radic. Res. | pmid:17015268 |
| Jun HJ et al. | Non-radioactive and colorimetric quantification of monocyte adhesion to endothelial cells in early atherogenesis. | 2006 | Biotechnol. Lett. | pmid:17028917 |
| Takahashi K et al. | gamma-tocopherol, but not alpha-tocopherol, potently inhibits neointimal formation induced by vascular injury in insulin resistant rats. | 2006 | J. Mol. Cell. Cardiol. | pmid:16876819 |
| Daza A et al. | Effect of age at the beginning of the free-range fattening period on growth and carcass and fat quality in Iberian pigs. | 2006 | Arch Anim Nutr | pmid:16921928 |
| Dietrich M et al. | Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A review. | 2006 | J Am Coll Nutr | pmid:16943450 |
| Kobayashi S | [UVB-induced skin damage and the protection/treatment--effects of a novel, hydrophilic gamma-tocopherol derivative]. | 2006 | Yakugaku Zasshi | pmid:16946583 |
| Scholl TO et al. | Vitamin E: maternal concentrations are associated with fetal growth. | 2006 | Am. J. Clin. Nutr. | pmid:17158428 |
| Ford ES et al. | Distribution of serum concentrations of alpha-tocopherol and gamma-tocopherol in the US population. | 2006 | Am. J. Clin. Nutr. | pmid:16895886 |
| Yoshida E et al. | Topical application of a novel, hydrophilic gamma-tocopherol derivative reduces photo-inflammation in mice skin. | 2006 | J. Invest. Dermatol. | pmid:16543897 |
| Campbell SE et al. | Comparative effects of RRR-alpha- and RRR-gamma-tocopherol on proliferation and apoptosis in human colon cancer cell lines. | 2006 | BMC Cancer | pmid:16417629 |
| Kuwabara Y et al. | Topical application of gamma-tocopherol derivative prevents UV-induced skin pigmentation. | 2006 | Biol. Pharm. Bull. | pmid:16755012 |
| Konger RL | A new wrinkle on topical vitamin E and photo-inflammation: Mechanistic studies of a hydrophilic gamma-tocopherol derivative compared with alpha-tocopherol. | 2006 | J. Invest. Dermatol. | pmid:16778813 |
| Djuric Z et al. | Effects of high fruit-vegetable and/or low-fat intervention on plasma micronutrient levels. | 2006 | J Am Coll Nutr | pmid:16766775 |
| Wolf G | How an increased intake of alpha-tocopherol can suppress the bioavailability of gamma-tocopherol. | 2006 | Nutr. Rev. | pmid:16808116 |
| Lehner F et al. | Metabolic effects of intravenous LCT or MCT/LCT lipid emulsions in preterm infants. | 2006 | J. Lipid Res. | pmid:16299352 |
| Itoh N et al. | gamma-Tocopherol attenuates MPTP-induced dopamine loss more efficiently than alpha-tocopherol in mouse brain. | 2006 | Neurosci. Lett. | pmid:16716512 |
| Morita N et al. | Vitamin E attenuates acute lung injury in sheep with burn and smoke inhalation injury. | 2006 | Redox Rep. | pmid:16686996 |
| Clarke MW et al. | Assessment of tocopherol metabolism and oxidative stress in familial hypobetalipoproteinemia. | 2006 | Clin. Chem. | pmid:16728468 |
| Radcliffe JD and Czajka-Narins DM | Lipids and tocopherols in serum and liver of female rats fed diets containing corn oil or cottonseed oil. | 2006 | Plant Foods Hum Nutr | pmid:16736386 |
| Romeu-Nadal M et al. | Determination of gamma- and alpha-tocopherols in human milk by a direct high-performance liquid chromatographic method with UV-vis detection and comparison with evaporative light scattering detection. | 2006 | J Chromatogr A | pmid:16574129 |
| Stephensen CB et al. | Vitamins C and E in adolescents and young adults with HIV infection. | 2006 | Am. J. Clin. Nutr. | pmid:16600941 |
| Drewel BT et al. | Less than adequate vitamin E status observed in a group of preschool boys and girls living in the United States. | 2006 | J. Nutr. Biochem. | pmid:16169199 |
| Newmark HL et al. | Mixed tocopherols inhibit azoxymethane-induced aberrant crypt foci in rats. | 2006 | Nutr Cancer | pmid:17176221 |
| Walter PB et al. | Oxidative stress and inflammation in iron-overloaded patients with beta-thalassaemia or sickle cell disease. | 2006 | Br. J. Haematol. | pmid:17010049 |
| Moreau RA and Hicks KB | Reinvestigation of the effect of heat pretreatment of corn fiber and corn germ on the levels of extractable tocopherols and tocotrienols. | 2006 | J. Agric. Food Chem. | pmid:17032015 |
| Palan PR et al. | Effects of menstrual cycle and oral contraceptive use on serum levels of lipid-soluble antioxidants. | 2006 | Am. J. Obstet. Gynecol. | pmid:16647895 |
| Klein A et al. | Alpha-tocopherol modulates phosphatidylserine externalization in erythrocytes: relevance in phospholipid transfer protein-deficient mice. | 2006 | Arterioscler. Thromb. Vasc. Biol. | pmid:16825594 |
| Chen J and Mehta JL | Angiotensin II-mediated oxidative stress and procollagen-1 expression in cardiac fibroblasts: blockade by pravastatin and pioglitazone. | 2006 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16714359 |
| Gabriel HE et al. | A comparison of carotenoids, retinoids, and tocopherols in the serum and buccal mucosa of chronic cigarette smokers versus nonsmokers. | 2006 | Cancer Epidemiol. Biomarkers Prev. | pmid:16702382 |
| Pednekar MS et al. | Association between tobacco use and body mass index in urban Indian population: implications for public health in India. | 2006 | BMC Public Health | pmid:16542418 |
| Sen CK et al. | Tocotrienols: Vitamin E beyond tocopherols. | 2006 | Life Sci. | pmid:16458936 |
| Jenab M et al. | Plasma and dietary carotenoid, retinol and tocopherol levels and the risk of gastric adenocarcinomas in the European prospective investigation into cancer and nutrition. | 2006 | Br. J. Cancer | pmid:16832408 |
| Shin MJ et al. | Relationship between insulin resistance and lipid peroxidation and antioxidant vitamins in hypercholesterolemic patients. | 2006 | Ann. Nutr. Metab. | pmid:16373994 |
| Fischer CP et al. | Vitamin E isoform-specific inhibition of the exercise-induced heat shock protein 72 expression in humans. | 2006 | J. Appl. Physiol. | pmid:16384840 |
| Elmadfa I et al. | Selected quality parameters of salmon and meat when fried with or without added fat. | 2006 | Int J Vitam Nutr Res | pmid:17243088 |
| Yasuoka S et al. | Topical application of a novel, water-soluble gamma-tocopherol derivative prevents UV-induced skin damage in mice. | 2005 Jul-Aug | Photochem. Photobiol. | pmid:15745421 |