Gamma-tocopherol is a lipid of Prenol Lipids (PR) class. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Adverse effects, Longterm Effects, Luteal Phase and Drug Interactions. Gamma-tocopherol often locates in Blood. The related lipids are Total cholesterol.
To understand associated biological information of gamma-tocopherol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-tocopherol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mishina TE et al. | Expression of a nitric oxide degrading enzyme induces a senescence programme in Arabidopsis. | 2007 | Plant Cell Environ. | pmid:17177875 |
| Cela J et al. | Accumulation of γ- rather than α-tocopherol alters ethylene signaling gene expression in the vte4 mutant of Arabidopsis thaliana. | 2011 | Plant Cell Physiol. | pmid:21719428 |
| Radcliffe JD and Czajka-Narins DM | Lipids and tocopherols in serum and liver of female rats fed diets containing corn oil or cottonseed oil. | 2006 | Plant Foods Hum Nutr | pmid:16736386 |
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| Kranner I et al. | Revival of a resurrection plant correlates with its antioxidant status. | 2002 | Plant J. | pmid:12100479 |
| Abbasi AR et al. | Specific roles of alpha- and gamma-tocopherol in abiotic stress responses of transgenic tobacco. | 2007 | Plant Physiol. | pmid:17293434 |
| Savidge B et al. | Isolation and characterization of homogentisate phytyltransferase genes from Synechocystis sp. PCC 6803 and Arabidopsis. | 2002 | Plant Physiol. | pmid:12011362 |
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| Collakova E and DellaPenna D | Homogentisate phytyltransferase activity is limiting for tocopherol biosynthesis in Arabidopsis. | 2003 | Plant Physiol. | pmid:12586887 |
| Sanità di Toppi L et al. | A bifasic response to cadmium stress in carrot: Early acclimatory mechanisms give way to root collapse further to prolonged metal exposure. | 2012 | Plant Physiol. Biochem. | pmid:22868210 |
| Voll LM and Abbasi AR | Are there Specific In Vivo Roles for alpha- and gamma-Tocopherol in Plants? | 2007 | Plant Signal Behav | pmid:19704593 |
| Desel C et al. | Nitration of gamma-tocopherol in plant tissues. | 2007 | Planta | pmid:17619201 |
| Nymark M et al. | An integrated analysis of molecular acclimation to high light in the marine diatom Phaeodactylum tricornutum. | 2009 | PLoS ONE | pmid:19888450 |
| Tang Y et al. | Roles of MPBQ-MT in Promoting α/γ-Tocopherol Production and Photosynthesis under High Light in Lettuce. | 2016 | PLoS ONE | pmid:26867015 |
| Lindshield BL et al. | Selenium, but not lycopene or vitamin E, decreases growth of transplantable dunning R3327-H rat prostate tumors. | 2010 | PLoS ONE | pmid:20454690 |
| Comhair SA et al. | Detrimental effects of environmental tobacco smoke in relation to asthma severity. | 2011 | PLoS ONE | pmid:21572527 |
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| Heuberger AL et al. | Metabolomic and functional genomic analyses reveal varietal differences in bioactive compounds of cooked rice. | 2010 | PLoS ONE | pmid:20886119 |
| Weinstein SJ et al. | Serum α-tocopherol and γ-tocopherol concentrations and prostate cancer risk in the PLCO Screening Trial: a nested case-control study. | 2012 | PLoS ONE | pmid:22792240 |
| Cui R et al. | Blood α-tocopherol, γ-tocopherol levels and risk of prostate cancer: a meta-analysis of prospective studies. | 2014 | PLoS ONE | pmid:24667740 |
| Patel CJ et al. | An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus. | 2010 | PLoS ONE | pmid:20505766 |
| Jiang Q et al. | gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15596715 |
| Spahis S et al. | Lipid profile, fatty acid composition and pro- and anti-oxidant status in pediatric patients with attention-deficit/hyperactivity disorder. | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18757191 | |
| Helmersson J et al. | Cyclooxygenase-mediated prostaglandin F2alpha is decreased in an elderly population treated with low-dose aspirin. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15763433 |
| Bauer SR et al. | Antioxidant and vitamin E transport genes and risk of high-grade prostate cancer and prostate cancer recurrence. | 2013 | Prostate | pmid:24038157 |
| Takahashi S et al. | Suppression of prostate cancer in a transgenic rat model via gamma-tocopherol activation of caspase signaling. | 2009 | Prostate | pmid:19143023 |
| Szołtysek-Bołdys I et al. | [The influence of smoking on plasma non-enzymatic antioxidant concentrations in active smokers (preliminary report)]. | 2006 | Prz. Lek. | pmid:17288194 |
| Frankenfeld CL et al. | Fruit and vegetable intakes in relation to plasma nutrient concentrations in women in Shanghai, China. | 2012 | Public Health Nutr | pmid:21729475 |
| Neuhouser ML et al. | Selected nutritional biomarkers predict diet quality. | 2003 | Public Health Nutr | pmid:14552672 |
| Shamim AA et al. | Plasma zinc, vitamin B(12) and α-tocopherol are positively and plasma γ-tocopherol is negatively associated with Hb concentration in early pregnancy in north-west Bangladesh. | 2013 | Public Health Nutr | pmid:23469947 |
| Yang M et al. | Validation of an FFQ to assess short-term antioxidant intake against 30 d food records and plasma biomarkers. | 2014 | Public Health Nutr | pmid:23164175 |
| Barker T et al. | Vitamin D deficiency associates with γ-tocopherol and quadriceps weakness but not inflammatory cytokines in subjects with knee osteoarthritis. | 2014 | Redox Biol | pmid:24624336 |
| Pfluger P et al. | Vitamin E: underestimated as an antioxidant. | 2004 | Redox Rep. | pmid:15606977 |
| Morita N et al. | Vitamin E attenuates acute lung injury in sheep with burn and smoke inhalation injury. | 2006 | Redox Rep. | pmid:16686996 |
| Kasimanickam RK et al. | Tocopherol induced angiogenesis in placental vascular network in late pregnant ewes. | 2010 | Reprod. Biol. Endocrinol. | pmid:20624307 |
| Kasimanickam RK et al. | Effect of tocopherol supplementation during last trimester of pregnancy on mRNA abundances of interleukins and angiogenesis in ovine placenta and uterus. | 2012 | Reprod. Biol. Endocrinol. | pmid:22269218 |
| Marchese ME et al. | The vitamin E isoforms α-tocopherol and γ-tocopherol have opposite associations with spirometric parameters: the CARDIA study. | 2014 | Respir. Res. | pmid:24629024 |
| Jang AS et al. | Antioxidant responsiveness in BALB/c mice exposed to ozone. | 2005 Jan-Feb | Respiration | pmid:15753639 |
| Ouyang S et al. | The role of tocopherol cyclase in salt stress tolerance of rice (Oryza sativa). | 2011 | Sci China Life Sci | pmid:21318489 |
| Chen F et al. | Association of vitamin C, vitamin D, vitamin E and risk of bladder cancer: a dose-response meta-analysis. | 2015 | Sci Rep | pmid:25905583 |
| Hirowatari Y et al. | Automated measurement method for the determination of vitamin E in plasma lipoprotein classes. | 2014 | Sci Rep | pmid:24522390 |
| Huang PH et al. | Vitamin E facilitates the inactivation of the kinase Akt by the phosphatase PHLPP1. | 2013 | Sci Signal | pmid:23512990 |
| Yamamoto Y et al. | Nebulization with γ-tocopherol ameliorates acute lung injury after burn and smoke inhalation in the ovine model. | 2012 | Shock | pmid:22266978 |
| Yamamoto Y et al. | γ-tocopherol nebulization decreases oxidative stress, arginase activity, and collagen deposition after burn and smoke inhalation in the ovine model. | 2012 | Shock | pmid:23160521 |
| Blaylock RL and Maroon J | Natural plant products and extracts that reduce immunoexcitotoxicity-associated neurodegeneration and promote repair within the central nervous system. | 2012 | Surg Neurol Int | pmid:22439110 |
| Petraglia AL et al. | Stuck at the bench: Potential natural neuroprotective compounds for concussion. | 2011 | Surg Neurol Int | pmid:22059141 |
| Kasimanickam RK and Kasimanickam VR | Effect of tocopherol supplementation on serum 8-epi-prostaglandin F2 alpha and adiponectin concentrations, and mRNA expression of PPARγ and related genes in ovine placenta and uterus. | 2011 | Theriogenology | pmid:21550107 |
| Cook-Mills J et al. | Interaction of vitamin E isoforms on asthma and allergic airway disease. | 2016 | Thorax | pmid:27257004 |