Gamma-tocopherol is a lipid of Prenol Lipids (PR) class. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Adverse effects, Longterm Effects, Luteal Phase and Drug Interactions. Gamma-tocopherol often locates in Blood. The related lipids are Total cholesterol.
To understand associated biological information of gamma-tocopherol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-tocopherol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mao Y et al. | Chemical Composition Analysis, Sensory, and Feasibility Study of Tree Peony Seed. | 2017 | J. Food Sci. | pmid:28135396 |
| Shin J et al. | Gamma-tocopherol supplementation ameliorated hyper-inflammatory response during the early cutaneous wound healing in alloxan-induced diabetic mice. | 2017 | Exp. Biol. Med. (Maywood) | pmid:28211759 |
| Chen JX et al. | δ- and γ-tocopherols inhibit phIP/DSS-induced colon carcinogenesis by protection against early cellular and DNA damages. | 2017 | Mol. Carcinog. | pmid:27175800 |
| Wu YM et al. | Comparable Function of γ-Tocopherols in Asthma Remission by Affecting Eotaxin and IL-4. | 2016 Jul-Aug | Adv Clin Exp Med | pmid:27629837 |
| Ogita T et al. | Identification and evaluation of antioxidants in Japanese parsley. | 2016 | Int J Food Sci Nutr | pmid:27075296 |
| Tang Y et al. | Roles of MPBQ-MT in Promoting α/γ-Tocopherol Production and Photosynthesis under High Light in Lettuce. | 2016 | PLoS ONE | pmid:26867015 |
| Stuetz W et al. | Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35-74 Years) General Population: A Cross-Sectional Study in Six European Countries. | 2016 | Nutrients | pmid:27706032 |
| Lewis NA et al. | Critical Difference and Biological Variation in Biomarkers of Oxidative Stress and Nutritional Status in Athletes. | 2016 | PLoS ONE | pmid:26930475 |
| Mumford SL et al. | Serum Antioxidants Are Associated with Serum Reproductive Hormones and Ovulation among Healthy Women. | 2016 | J. Nutr. | pmid:26581679 |
| Debbabi M et al. | Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells. | 2016 | Int J Mol Sci | pmid:27897980 |
| Cook-Mills J et al. | Interaction of vitamin E isoforms on asthma and allergic airway disease. | 2016 | Thorax | pmid:27257004 |
| Abdala-Valencia H et al. | γ-Tocopherol supplementation of allergic female mice augments development of CD11c+CD11b+ dendritic cells in utero and allergic inflammation in neonates. | 2016 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:26801566 |
| Hanson C et al. | Serum tocopherol levels and vitamin E intake are associated with lung function in the normative aging study. | 2016 | Clin Nutr | pmid:25715694 |
| Das Gupta S et al. | Dietary γ-Tocopherol-Rich Mixture Inhibits Estrogen-Induced Mammary Tumorigenesis by Modulating Estrogen Metabolism, Antioxidant Response, and PPARγ. | 2015 | Cancer Prev Res (Phila) | pmid:26130252 |
| Mah E et al. | Greater γ-tocopherol status during acute smoking abstinence with nicotine replacement therapy improved vascular endothelial function by decreasing 8-iso-15(S)-prostaglandin F2α. | 2015 | Exp. Biol. Med. (Maywood) | pmid:25361769 |
| West KP et al. | A Plasma α-Tocopherome Can Be Identified from Proteins Associated with Vitamin E Status in School-Aged Children of Nepal. | 2015 | J. Nutr. | pmid:26446483 |
| Zhao Y et al. | α-Tocopherol Stereoisomers in Human Plasma Are Affected by the Level and Form of the Vitamin E Supplement Used. | 2015 | J. Nutr. | pmid:26290004 |
| Prevc T et al. | Rapid Estimation of Tocopherol Content in Linseed and Sunflower Oils-Reactivity and Assay. | 2015 | Molecules | pmid:26287138 |
| Braz MG et al. | Isoflurane and Propofol Contribute to Increasing the Antioxidant Status of Patients During Minor Elective Surgery: A Randomized Clinical Study. | 2015 | Medicine (Baltimore) | pmid:26252290 |
| Morimoto Y et al. | Adherence to cancer prevention recommendations and antioxidant and inflammatory status in premenopausal women. | 2015 | Br. J. Nutr. | pmid:26051510 |
| Wang Y et al. | Vitamin E γ-Tocotrienol Inhibits Cytokine-Stimulated NF-κB Activation by Induction of Anti-Inflammatory A20 via Stress Adaptive Response Due to Modulation of Sphingolipids. | 2015 | J. Immunol. | pmid:26002975 |
| Pei R et al. | α-Tocopherol supplementation reduces 5-nitro-γ-tocopherol accumulation by decreasing γ-tocopherol in young adult smokers. | 2015 | Free Radic. Res. | pmid:25966030 |
| Zong G et al. | Serum α-Tocopherol Has a Nonlinear Inverse Association with Periodontitis among US Adults. | 2015 | J. Nutr. | pmid:25934661 |
| Chen F et al. | Association of vitamin C, vitamin D, vitamin E and risk of bladder cancer: a dose-response meta-analysis. | 2015 | Sci Rep | pmid:25905583 |
| Ipek M et al. | Identification of molecular markers associated with fruit traits in olive and assessment of olive core collection with AFLP markers and fruit traits. | 2015 | Genet. Mol. Res. | pmid:25867425 |
| Genkinger JM et al. | Prenatal polycyclic aromatic hydrocarbon (PAH) exposure, antioxidant levels and behavioral development of children ages 6-9. | 2015 | Environ. Res. | pmid:25863187 |
| Yan R et al. | Exploitation of the ability of γ-tocopherol to facilitate membrane co-localization of Akt and PHLPP1 to develop PHLPP1-targeted Akt inhibitors. | 2015 | J. Med. Chem. | pmid:25689347 |
| Shamim AA et al. | First-trimester plasma tocopherols are associated with risk of miscarriage in rural Bangladesh. | 2015 | Am. J. Clin. Nutr. | pmid:25646326 |
| Li Y et al. | Effects of vitamin E from supplements and diet on colonic α- and γ-tocopherol concentrations in persons at increased colon cancer risk. | 2015 | Nutr Cancer | pmid:25372556 |
| Morris MC et al. | Brain tocopherols related to Alzheimer's disease neuropathology in humans. | 2015 | Alzheimers Dement | pmid:24589434 |
| Mills K et al. | Vitamin E, γ-tocopherol, diminishes ex vivo basophil response to dust mite allergen. | 2014 | Allergy | pmid:24697338 |
| Chai W et al. | Serum coenzyme Qâ‚â‚€, α-tocopherol, γ-tocopherol, and C-reactive protein levels and body mass index in adolescent and premenopausal females. | 2014 | J Am Coll Nutr | pmid:24809382 |
| Chitarrini G et al. | Buckwheat achenes antioxidant profile modulates Aspergillus flavus growth and aflatoxin production. | 2014 | Int. J. Food Microbiol. | pmid:25108759 |
| Cash WJ et al. | Disordered vascular compliance in haemochromatosis. | 2014 | Ir J Med Sci | pmid:24000100 |
| Yang M et al. | Validation of an FFQ to assess short-term antioxidant intake against 30 d food records and plasma biomarkers. | 2014 | Public Health Nutr | pmid:23164175 |
| Wagner JG et al. | Supplementation with γ-tocopherol attenuates endotoxin-induced airway neutrophil and mucous cell responses in rats. | 2014 | Free Radic. Biol. Med. | pmid:24333275 |
| Marchese ME et al. | The vitamin E isoforms α-tocopherol and γ-tocopherol have opposite associations with spirometric parameters: the CARDIA study. | 2014 | Respir. Res. | pmid:24629024 |
| Cui R et al. | Blood α-tocopherol, γ-tocopherol levels and risk of prostate cancer: a meta-analysis of prospective studies. | 2014 | PLoS ONE | pmid:24667740 |
| Menoyo D et al. | Atlantic salmon (Salmo salar L.) as a marine functional source of gamma-tocopherol. | 2014 | Mar Drugs | pmid:25501796 |
| Singh CK et al. | Methaneseleninic acid and γ-Tocopherol combination inhibits prostate tumor growth in Vivo in a xenograft mouse model. | 2014 | Oncotarget | pmid:25004451 |
| Bazongo P et al. | Characteristics, composition and oxidative stability of Lannea microcarpa seed and seed oil. | 2014 | Molecules | pmid:24566330 |
| Barker T et al. | Vitamin D deficiency associates with γ-tocopherol and quadriceps weakness but not inflammatory cytokines in subjects with knee osteoarthritis. | 2014 | Redox Biol | pmid:24624336 |
| Hirowatari Y et al. | Automated measurement method for the determination of vitamin E in plasma lipoprotein classes. | 2014 | Sci Rep | pmid:24522390 |
| Zou Y et al. | Associations of serum retinol, α-tocopherol, and γ-tocopherol with biomarkers among healthy Japanese men. | 2014 | Int J Environ Res Public Health | pmid:24487454 |
| Haddad EH et al. | Effect of a walnut meal on postprandial oxidative stress and antioxidants in healthy individuals. | 2014 | Nutr J | pmid:24410903 |
| Anzai K et al. | Gamma-tocopherol-N,N-dimethylglycine ester as a potent post-irradiation mitigator against whole body X-irradiation-induced bone marrow death in mice. | 2014 | J. Radiat. Res. | pmid:23908555 |
| Yuan L et al. | Glutathione S-transferase M1 and T1 gene polymorphisms with consumption of high fruit-juice and vegetable diet affect antioxidant capacity in healthy adults. | 2013 Jul-Aug | Nutrition | pmid:23422534 |
| Mangialasche F et al. | Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol. | 2013 | J. Intern. Med. | pmid:23343471 |
| Vance TM et al. | Dietary antioxidants and prostate cancer: a review. | 2013 | Nutr Cancer | pmid:23909722 |
| Yang D et al. | Antioxidative activities of Ginkgo biloba extract on oil/water emulsion system prepared from an enzymatically modified lipid containing alpha-linolenic acid. | 2013 | J. Food Sci. | pmid:23278764 |
| Torricelli P et al. | γ-Tocopherol inhibits human prostate cancer cell proliferation by up-regulation of transglutaminase 2 and down-regulation of cyclins. | 2013 | Amino Acids | pmid:22460364 |
| Martysiak-Żurowska D et al. | Concentrations of alpha- and gamma-tocopherols in human breast milk during the first months of lactation and in infant formulas. | 2013 | Matern Child Nutr | pmid:22513202 |
| Müllner E et al. | Genome damage in peripheral blood lymphocytes of diabetic and non-diabetic individuals after intervention with vegetables and plant oil. | 2013 | Mutagenesis | pmid:23340810 |
| Smolarek AK et al. | Dietary tocopherols inhibit cell proliferation, regulate expression of ERα, PPARγ, and Nrf2, and decrease serum inflammatory markers during the development of mammary hyperplasia. | 2013 | Mol. Carcinog. | pmid:22389237 |
| Mah E et al. | Supplementation of a γ-tocopherol-rich mixture of tocopherols in healthy men protects against vascular endothelial dysfunction induced by postprandial hyperglycemia. | 2013 | J. Nutr. Biochem. | pmid:22841396 |
| Shamim AA et al. | Plasma zinc, vitamin B(12) and α-tocopherol are positively and plasma γ-tocopherol is negatively associated with Hb concentration in early pregnancy in north-west Bangladesh. | 2013 | Public Health Nutr | pmid:23469947 |
| Hernandez ML et al. | Vitamin E, γ-tocopherol, reduces airway neutrophil recruitment after inhaled endotoxin challenge in rats and in healthy volunteers. | 2013 | Free Radic. Biol. Med. | pmid:23402870 |
| Geiser M et al. | Effects of ex vivo γ-tocopherol on airway macrophage function in healthy and mild allergic asthmatics. | 2013 | J Innate Immun | pmid:23689260 |
| Garaiova I et al. | Effect of a plant sterol, fish oil and B vitamin combination on cardiovascular risk factors in hypercholesterolemic children and adolescents: a pilot study. | 2013 | Nutr J | pmid:23297818 |
| Alipour M et al. | Safety and pharmacokinetic studies of liposomal antioxidant formulations containing N-acetylcysteine, α-tocopherol or γ-tocopherol in beagle dogs. | 2013 | Toxicol. Mech. Methods | pmid:23384394 |
| Huang PH et al. | Vitamin E facilitates the inactivation of the kinase Akt by the phosphatase PHLPP1. | 2013 | Sci Signal | pmid:23512990 |
| Prokopowicz A et al. | Effect of occupational lead exposure on α- and γ-tocopherol concentration in plasma. | 2013 | Occup Environ Med | pmid:23378446 |
| Sanches LD et al. | Protective effect of γ-tocopherol-enriched diet on N-methyl-N-nitrosourea-induced epithelial dysplasia in rat ventral prostate. | 2013 | Int J Exp Pathol | pmid:24205794 |
| Abdala-Valencia H et al. | Vitamin E isoforms as modulators of lung inflammation. | 2013 | Nutrients | pmid:24184873 |
| Bauer SR et al. | Antioxidant and vitamin E transport genes and risk of high-grade prostate cancer and prostate cancer recurrence. | 2013 | Prostate | pmid:24038157 |
| Zingg JM et al. | In vivo regulation of gene transcription by alpha- and gamma-tocopherol in murine T lymphocytes. | 2013 | Arch. Biochem. Biophys. | pmid:23993952 |
| Uchida T et al. | α-Tocopherol does not accelerate depletion of γ-tocopherol and tocotrienol or excretion of their metabolites in rats. | 2013 | Lipids | pmid:23700248 |
| Hanzawa F et al. | Dietary sesame seed and its lignan, sesamin, increase tocopherol and phylloquinone concentrations in male rats. | 2013 | J. Nutr. | pmid:23700348 |
| Tasanarong A et al. | New strategy of α- and γ-tocopherol to prevent contrast-induced acute kidney injury in chronic kidney disease patients undergoing elective coronary procedures. | 2013 | Nephrol. Dial. Transplant. | pmid:23314316 |
| Jiang Q et al. | Gamma-tocopherol attenuates moderate but not severe colitis and suppresses moderate colitis-promoted colon tumorigenesis in mice. | 2013 | Free Radic. Biol. Med. | pmid:24013093 |
| Semchuk NM et al. | Effect of short-term salt stress on oxidative stress markers and antioxidant enzymes activity in tocopherol-deficient Arabidopsis thaliana plants. | 2012 Jul-Aug | Ukr Biokhim Zh (1999) | pmid:22946299 |
| McCary CA et al. | Vitamin E isoforms directly bind PKCα and differentially regulate activation of PKCα. | 2012 | Biochem. J. | pmid:21933153 |
| McCarty MF | Addendum: Gamma-tocopherol, cox-2, and cancer risk. | 2012 | Med. Hypotheses | pmid:22285625 |
| Li G et al. | The antioxidant and anti-inflammatory activities of tocopherols are independent of Nrf2 in mice. | 2012 | Free Radic. Biol. Med. | pmid:22226829 |
| Wang Y et al. | Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells. | 2012 | J. Nutr. Biochem. | pmid:21764283 |
| Hwang ES et al. | Effects of heat treatment on the carotenoid and tocopherol composition of tomato. | 2012 | J. Food Sci. | pmid:22950575 |
| Fairus S et al. | Alpha-tocotrienol is the most abundant tocotrienol isomer circulated in plasma and lipoproteins after postprandial tocotrienol-rich vitamin E supplementation. | 2012 | Nutr J | pmid:22252050 |
| Gopalan A et al. | Involvement of de novo ceramide synthesis in gamma-tocopherol and gamma-tocotrienol-induced apoptosis in human breast cancer cells. | 2012 | Mol Nutr Food Res | pmid:23065795 |
| Guan F et al. | δ- and γ-tocopherols, but not α-tocopherol, inhibit colon carcinogenesis in azoxymethane-treated F344 rats. | 2012 | Cancer Prev Res (Phila) | pmid:22366914 |
| Li CJ et al. | Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNF-α) Induced Inflammatory Response in Bovine Cells. | 2012 | Gene Regul Syst Bio | pmid:22267916 |
| Then SM et al. | γ-Tocotrienol does not substantially protect DS neurons from hydrogen peroxide-induced oxidative injury. | 2012 | Nutr Metab (Lond) | pmid:22217149 |
| Abuasal BS et al. | Comparison of the intestinal absorption and bioavailability of γ-tocotrienol and α-tocopherol: in vitro, in situ and in vivo studies. | 2012 | Biopharm Drug Dispos | pmid:22528033 |
| GarcÃa-Moreno MJ et al. | Genetic basis of unstable expression of high gamma-tocopherol content in sunflower seeds. | 2012 | BMC Plant Biol. | pmid:22607470 |
| Yamamoto Y et al. | Nebulization with γ-tocopherol ameliorates acute lung injury after burn and smoke inhalation in the ovine model. | 2012 | Shock | pmid:22266978 |
| Kasimanickam RK et al. | Effect of tocopherol supplementation during last trimester of pregnancy on mRNA abundances of interleukins and angiogenesis in ovine placenta and uterus. | 2012 | Reprod. Biol. Endocrinol. | pmid:22269218 |
| Chorell E et al. | Physical fitness level is reflected by alterations in the human plasma metabolome. | 2012 | Mol Biosyst | pmid:22282227 |
| Hamidi MS et al. | Effects of vitamin E on bone turnover markers among US postmenopausal women. | 2012 | J. Bone Miner. Res. | pmid:22308007 |
| Andersson SC et al. | Tocopherols in rose hips (Rosa spp.) during ripening. | 2012 | J. Sci. Food Agric. | pmid:22311859 |
| Kim S et al. | Comparison of three tocopherol analogs as an inhibitor of production of proinflammatory mediators in macrophages. | 2012 | J. Pharmacol. Sci. | pmid:22302019 |
| González E et al. | Two by-products of the olive oil extraction industry as oleic acid supplement source for Iberian pigs: effect on the meat's chemical composition and induced lipoperoxidation. | 2012 | J. Sci. Food Agric. | pmid:22488674 |
| Nagao M et al. | Relation of serum α- and γ-tocopherol levels to cardiovascular disease-related mortality among Japanese men and women. | 2012 | J Epidemiol | pmid:22672959 |
| Farré G et al. | Transgenic rice grains expressing a heterologous Ï-hydroxyphenylpyruvate dioxygenase shift tocopherol synthesis from the γ to the α isoform without increasing absolute tocopherol levels. | 2012 | Transgenic Res. | pmid:22361804 |
| Gawlik M et al. | The impact of Triton WR-1339 induced hyperlipidemia on the effects of benzo(a)pyrene or guaiacol on α- and γ-tocopherol pools and selected markers of pro-/antioxidative balance in rat plasma and erythrocytes. | 2012 | Environ. Toxicol. Pharmacol. | pmid:22387351 |
| Reboul E et al. | Respective contributions of intestinal Niemann-Pick C1-like 1 and scavenger receptor class B type I to cholesterol and tocopherol uptake: in vivo v. in vitro studies. | 2012 | Br. J. Nutr. | pmid:21929836 |
| Sanità di Toppi L et al. | A bifasic response to cadmium stress in carrot: Early acclimatory mechanisms give way to root collapse further to prolonged metal exposure. | 2012 | Plant Physiol. Biochem. | pmid:22868210 |
| Sánchez-Muniz FJ et al. | The antioxidant status response to low-fat and walnut paste-enriched meat differs in volunteers at high cardiovascular Risk carrying different PON-1 polymorphisms. | 2012 | J Am Coll Nutr | pmid:23204156 |
| Blaylock RL and Maroon J | Natural plant products and extracts that reduce immunoexcitotoxicity-associated neurodegeneration and promote repair within the central nervous system. | 2012 | Surg Neurol Int | pmid:22439110 |
| Yamamoto Y et al. | γ-tocopherol nebulization decreases oxidative stress, arginase activity, and collagen deposition after burn and smoke inhalation in the ovine model. | 2012 | Shock | pmid:23160521 |
| Vujasinović V et al. | Optimization of hull-less pumpkin seed roasting conditions using response surface methodology. | 2012 | J. Food Sci. | pmid:23163936 |
| Baumeister P et al. | Curcumin and other polyphenolic compounds in head and neck cancer chemoprevention. | 2012 | Oxid Med Cell Longev | pmid:22690273 |