| MeSH term | MeSH ID | Detail |
|---|---|---|
| Vitamin K Deficiency | D014813 | 5 associated lipids |
| Thromboembolism | D013923 | 6 associated lipids |
| Exanthema | D005076 | 11 associated lipids |
Total
3
phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phylloquinone?
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with phylloquinone
PubChem Associated disorders and diseases
What pathways are associated with phylloquinone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phylloquinone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phylloquinone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phylloquinone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phylloquinone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phylloquinone?
Knock-out
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with phylloquinone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jiang NX et al. | [Vitamin K epoxide reductase complex 1 gene polymorphism and warfarin dose requirement in Chinese patients]. | 2007 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:17961434 |
| Liu J et al. | [Level of vitamin K-dependent coagulation factors in premature infants and the influence of maternal antenatal administration of vitamin K1 on their activity]. | 2005 | Zhonghua Er Ke Za Zhi | pmid:16412352 |
| Chen XH et al. | [Analysis of thirteen cases with secondary coagulation disorder caused by raticide exposure]. | 2010 | Zhonghua Er Ke Za Zhi | pmid:21055312 |
| Sun AY and Cheng JS | Neuroprotective effects of poly (ADP-ribose) polymerase inhibitors in transient focal cerebral ischemia of rats. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374629 |
| Chen JW et al. | [Analysis of vitamins and inorganic elements in the water extracts of Radix Changii]. | 2004 | Zhong Xi Yi Jie He Xue Bao | pmid:15383265 |
| Rogner G | [Changes of blood coagulation potential during the prevention of hemorrhage in newborn infants born at risk]. | 1974 | Zentralbl Gynakol | pmid:4450830 |
| Sewkow S et al. | [Nutritional requirements of Bacteroides melaninogenicus]. | 1974 | Zentralbl Bakteriol Orig A | pmid:4154688 |
| Hoppe W | [The importance of the treatment with marcumar in oral surgery]. | 1967 | Zahnarztl Prax | pmid:5298417 |
| Lichtenthaler HK and Tevini M | [Effect of UV-rays on the lipoquinone-pigment composition of isolated spinach chloroplasts]. | 1969 | Z. Naturforsch. B | pmid:4390030 |
| Lichtenthaler HK | [Formation of excess plastidquinones in the leaves of Ficus elastica Roxb]. | 1969 | Z. Naturforsch. B | pmid:4391381 |
| Schurgers LJ et al. | Role of vitamin K and vitamin K-dependent proteins in vascular calcification. | 2001 | Z Kardiol | pmid:11374034 |
| Kolb E | [Recent discoveries on the biochemical significance of vitamin K and some characteristics of vitamin K dependent proteins]. | 1981 | Z Gesamte Inn Med | pmid:7331379 |
| Gessl H et al. | [Reducing lipid peroxidation of stored frozen trout fillet by supplementing feed with vitamin E]. | 1995 | Z Ernahrungswiss | pmid:7502541 |
| Su Q and Li Y | Interaction between warfarin and the herbal product Shengmai-yin: a case report of intracerebral hematoma. | 2010 | Yonsei Med. J. | pmid:20635460 |
| Hayakawa Y and Takamura K | [Reaction of vitamin K3 with cysteine in aqueous ethanol and consecutive determination of vitamins K (author's transl)]. | 1974 | Yakugaku Zasshi | pmid:4476774 |
| Nakata Y et al. | [Studies on photodegradation of vitamin K1. I. Determination of vitamin K1 by gas-liquid chromatography (author's transl)]. | 1976 | Yakugaku Zasshi | pmid:943509 |
| Hiroshima O et al. | [Determination of phylloquinone-2,3-epoxide and menaquinone-4-2,3-epoxide in biological materials by high performance liquid chromatography and fluorometric reaction detection (author's transl)]. | 1979 | Yakugaku Zasshi | pmid:544742 |
| Nagata M et al. | [Pharmaceutical studies on commercial phytonadion tablets and effect of polysorbate 80 on the dissolution test (author's transl)]. | 1979 | Yakugaku Zasshi | pmid:544751 |
| Sloane N | Enzymic hydroxylation of benzo(alpha)pyrene at the 6-position by vitamin K1-hydroperoxide and rat lung hydroperoxidase. | 1981 | Xenobiotica | pmid:6272502 |
| Du W et al. | Vitamin K1 enhances sorafenib-induced growth inhibition and apoptosis of human malignant glioma cells by blocking the Raf/MEK/ERK pathway. | 2012 | World J Surg Oncol | pmid:22520038 |