MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin K Deficiency | D014813 | 5 associated lipids |
Thromboembolism | D013923 | 6 associated lipids |
Exanthema | D005076 | 11 associated lipids |
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with phylloquinone
MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin K Deficiency | D014813 | 5 associated lipids |
Thromboembolism | D013923 | 6 associated lipids |
Exanthema | D005076 | 11 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Roe DE et al. | Multilaboratory comparison of growth characteristics for anaerobes, using 5 different agar media. | 2002 | Clin. Infect. Dis. | pmid:12173106 |
Roe DE et al. | Multilaboratory comparison of anaerobe susceptibility results using 3 different agar media. | 2002 | Clin. Infect. Dis. | pmid:12173107 |
Cook KK et al. | Measurement of cis and trans isomers of vitamin K1 in rat tissues by liquid chromatography with a C30 column. | 2002 Jul-Aug | J AOAC Int | pmid:12180675 |
Booth SL et al. | Phylloquinone absorption from phylloquinone-fortified oil is greater than from a vegetable in younger and older men and women. | 2002 | J. Nutr. | pmid:12221218 |
Rigby SE et al. | Photoaccumulation of the PsaB phyllosemiquinone in photosystem I of Chlamydomonas reinhardtii. | 2002 | Biochim. Biophys. Acta | pmid:12351214 |
Fregin A et al. | Homozygosity mapping of a second gene locus for hereditary combined deficiency of vitamin K-dependent clotting factors to the centromeric region of chromosome 16. | 2002 | Blood | pmid:12384421 |
Riegert-Johnson DL and Volcheck GW | The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. | 2002 | Ann. Allergy Asthma Immunol. | pmid:12392385 |
Binkley NC et al. | A high phylloquinone intake is required to achieve maximal osteocalcin gamma-carboxylation. | 2002 | Am. J. Clin. Nutr. | pmid:12399278 |
Shimizu N et al. | Shift of serum osteocalcin components between cord blood and blood at day 5 of life. | 2002 | Pediatr. Res. | pmid:12409510 |
Lindquist J and Farroha SM | Application of differential pulse polarography to the assay of vitamins. | 1975 | Analyst | pmid:124542 |