phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Vitamin K Deficiency D014813 5 associated lipids
Thromboembolism D013923 6 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
ASANO A et al. The new synthetic 6-chromanyl phosphate of vitamin K1(20) and its behavior in an enzymatic system from Mycobacterium phlei. 1962 J. Biol. Chem. pmid:13862733
GUSTAFSSON BE et al. Effects of vitamin K-active compounds and intestinal microorganisms in vitamin K-deficient germfree rats. 1962 J. Nutr. pmid:13951405
BARNHART MI and ANDERSON GF Cellular study of drug alteration of prothrombin synthesis. 1962 Biochem. Pharmacol. pmid:13969408
ZINKHAM WH Peripheral blood and bilirubin values in normal full-term primaquine-sensitive Negro infants: effect of vitamin K. 1963 Pediatrics pmid:14003753
SHOSHKES M and ODZE M Comparison of the thrombotest with the modified Quick test. Drug-induced hypoprothrombinemia countered with phytonadione. 1963 Circulation pmid:13988686
SHOSHKES M et al. Comparison between the one-stage prothrombin time and factor VII and X complex determination in bishydroxycoumarin-induced hypoprothrombinemia countered by phytonadione. 1963 J Newark Beth Isr Hosp pmid:13988687
YOSHIDA K et al. [Effect of synthetic vitamin K1 on prothrombin, factor VII complex and factor IX in premature infants]. 1963 Paediatr Jpn pmid:14002672
HENNINGER MD et al. Restoration of ferricyanide reduction in acetone-extracted chloroplasts by beta and gamma tocopherol quinones. 1963 Biochem. Biophys. Res. Commun. pmid:13953779
ISHITE K et al. [Trial use of Kaywan in surgical hepatobiliary diseases, with special reference to hemorrhagic diathesis]. 1963 Chiryo pmid:13956881
BEYER RE The effect of ultraviolet light on mitochondria. VII. Restoration of dinitrophenol-activated adenosinetri-phosphatase by vitamin K following inhibition by farultraviolet light. 1963 Can J Biochem Physiol pmid:13967934