| MeSH term | MeSH ID | Detail |
|---|---|---|
| Vitamin K Deficiency | D014813 | 5 associated lipids |
| Thromboembolism | D013923 | 6 associated lipids |
| Exanthema | D005076 | 11 associated lipids |
Total
3
phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phylloquinone?
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with phylloquinone
PubChem Associated disorders and diseases
What pathways are associated with phylloquinone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phylloquinone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phylloquinone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phylloquinone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phylloquinone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phylloquinone?
Knock-out
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with phylloquinone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tirapelli CR et al. | Vitamin K1 attenuates hypoxia-induced relaxation of rat carotid artery. | 2002 | Pharmacol. Res. | pmid:12457620 |
| Anderson SS et al. | Electron transfer across membranes using vitamin K1 and coenzyme Q10 as carrier molecules. | 1976 | Nature | pmid:1246352 |
| Shinkarev VP et al. | Modeling of the P700+ charge recombination kinetics with phylloquinone and plastoquinone-9 in the A1 site of photosystem I. | 2002 | Biophys. J. | pmid:12496065 |
| Golbeck JH | The binding of cofactors to photosystem I analyzed by spectroscopic and mutagenic methods. | 2003 | Annu Rev Biophys Biomol Struct | pmid:12524325 |
| Essalihi R et al. | A new model of isolated systolic hypertension induced by chronic warfarin and vitamin K1 treatment. | 2003 | Am. J. Hypertens. | pmid:12559675 |
| Pereira SP et al. | Intestinal absorption of mixed micellar phylloquinone (vitamin K1) is unreliable in infants with conjugated hyperbilirubinaemia: implications for oral prophylaxis of vitamin K deficiency bleeding. | 2003 | Arch. Dis. Child. Fetal Neonatal Ed. | pmid:12598499 |
| Poli D et al. | Safety and effectiveness of low dose oral vitamin K1 administration in asymptomatic out-patients on warfarin or acenocoumarol with excessive anticoagulation. | 2003 | Haematologica | pmid:12604423 |
| Blake CJ | Committee on food nutrition. Fat-soluble vitamins. | 2003 Jan-Feb | J AOAC Int | pmid:12607754 |
| Wade Johnson T et al. | The menD and menE homologs code for 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylate synthase and O-succinylbenzoic acid-CoA synthase in the phylloquinone biosynthetic pathway of Synechocystis sp. PCC 6803. | 2003 | Biochim. Biophys. Acta | pmid:12615349 |
| Gong XM et al. | Control of electron transport in photosystem I by the iron-sulfur cluster FX in response to intra- and intersubunit interactions. | 2003 | J. Biol. Chem. | pmid:12626505 |