MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin K Deficiency | D014813 | 5 associated lipids |
Thromboembolism | D013923 | 6 associated lipids |
Exanthema | D005076 | 11 associated lipids |
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with phylloquinone
MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin K Deficiency | D014813 | 5 associated lipids |
Thromboembolism | D013923 | 6 associated lipids |
Exanthema | D005076 | 11 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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OMORI A | [ANTIHEMOPHILIC GLOBULIN CONSUMPTION DURING BLOOD COAGULATION]. | 1963 | Nippon Naika Gakkai Zasshi | pmid:14156201 |
DOKU HC et al. | THROMBOPLASTIC ACTIVITY OF HUMAN SALIVA IN PATIENTS UNDER PROLONGED ANTICOAGULATION THERAPY. | 1964 May-Jun | J. Dent. Res. | pmid:14159035 |
STEFANINI F et al. | [CLINICAL RESEARCH ON POST-EXTRACTIVE HEMORRHAGES]. | 1963 Oct-Dec | Omnia Med Ther | pmid:14159130 |
CABASSA N and SCIASCIA R | [CHANGES IN THE ERYTHROCYTE UPTAKE OF T3-I-131 IN RATS AFTER ADMINISTRATION OF COAGULANTS (PROTAMINE SULFATE AND VITAMIN K 1)]. | 1964 Jan-Feb | Radiobiol Radioter Fis Med | pmid:14171481 |
Barr R et al. | Destruction of vitamin K1 of cultured carrot cells by ultraviolet radiation and its effect on plasma membrane electron transport reactions. | 1992 | Biochem. Int. | pmid:1417882 |
KOZINN PJ et al. | MASSIVE HEMORRHAGE--SCALPS OF NEWBORN INFANTS. | 1964 | Am. J. Dis. Child. | pmid:14186662 |
SOREL et al. | [100 HOSPITALIZED CASES OF WHOOPING COUGH. STATISTICS AND THERAPEUTIC CONSIDERATIONS]. | 1964 | Arch. Fr. Pediatr. | pmid:14195286 |
MCKENNA M et al. | A SECOND NAPHTHOQUINONE IN SPINACH CHLOROPLASTS. | 1964 | Nature | pmid:14202379 |
PIGUET B and BERTHEUIL F | [ALLERGIC CUTANEOUS COMPLICATIONS CAUSED BY A SYNTHETIC INJECTABLE VITAMIN K1 PREPARATION]. | 1964 Jul-Aug | Bull Soc Fr Dermatol Syphiligr | pmid:14210517 |
von Kries R et al. | Late hemorrhagic disease of newborn: a case with increased vitamin K requirement. | 1992 | Acta Paediatr. | pmid:1421921 |